Find hotels in La Mesa from ¥8,224

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Our top choices for La Mesa hotels

Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
4.0 star property
Tocumen
8.4 out of 10, Very Good, (2316)
"The room was clean and the staff were nice! "
United States
CECILIA
The price is ¥17,131
¥18,844 total
includes taxes & fees
Dec 23 - Dec 24
Crowne Plaza Panama Airport by IHG

ORHO HOTEL BOUTIQUE PANAMA Airport

ORHO HOTEL BOUTIQUE PANAMA Airport
2.0 star property
Tocumen
9.0 out of 10, Wonderful, (34)
"It was a cool unique antique place that had modern touches. The staff was very friendly and helpful. Will definitely stay again. "
United States
Clarissa
The price is ¥18,689
¥24,258 total
includes taxes & fees
Dec 13 - Dec 14
ORHO HOTEL BOUTIQUE PANAMA Airport

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
Tocumen
8.6 out of 10, Excellent, (1848)
"Very nice hotel centered around courtyard and pool. Convenient for airport "
Canada
Miles
The price is ¥19,475
¥21,423 total
includes taxes & fees
Dec 13 - Dec 14
Riande Aeropuerto Hotel & Casino

Aloft Panama

Aloft Panama
3.5 star property
San Francisco
8.8 out of 10, Excellent, (891)
"The staff was very friendly, rooms were clean and modern."
United States
Greg
The price is ¥18,222
¥20,044 total
includes taxes & fees
Dec 21 - Dec 22
Aloft Panama

Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
4.0 star property
Cerro Viento
8.8 out of 10, Excellent, (1004)
"Conveniently located near the airport and major shopping outlets."
United States
Greg
The price is ¥15,862
¥17,448 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Courtyard by Marriott Panama Metromall

Express Inn Panama International Airport Hostel

Express Inn Panama International Airport Hostel
1.5 star property
Tocumen
6.0 out of 10, (656)
"Perfect for a quick overnight before a flight out of PTY or a land and rest location. "
United States
Cecily
The price is ¥7,709
¥8,480 total
includes taxes & fees
Dec 13 - Dec 14
Express Inn Panama International Airport Hostel

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (637)
"As usual the stay was amazing in this hotel"
United States
Jose
The price is ¥36,093
¥39,702 total
includes taxes & fees
Dec 13 - Dec 14
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco
9.6 out of 10, Exceptional, (1107)
"Extra clean room, Breakfast menu very good"
United States
Alejandro
The price is ¥18,533
¥20,386 total
includes taxes & fees
Dec 24 - Dec 25
Ramada Plaza by Wyndham Panama Punta Pacifica

Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco
8.6 out of 10, Excellent, (989)
"Was amazing food was delicious and stay was great "
United States
Amanda
The price is ¥20,885
¥22,974 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Sheraton Grand Panama

The Westin Panama

The Westin Panama
4.0 star property
Costa del Este
9.0 out of 10, Wonderful, (308)
"Hotel was great and the staff was amazing "
United States
FREDRICK L.
The price is ¥30,671
¥33,738 total
includes taxes & fees
Dec 13 - Dec 14
The Westin Panama

Arcadia Condo Suites

Arcadia Condo Suites
2.5 star property
Costa del Este
9.4 out of 10, Exceptional, (157)
"Everything was great, helpful staff, great room , clean, excellent service!"
United States
Gregory Walter
The price is ¥10,279
¥18,502 total
includes taxes & fees
Dec 15 - Dec 16
Arcadia Condo Suites

Boutique Apartments Atlapa

Boutique Apartments Atlapa
3.0 star property
San Francisco
8.0 out of 10, Very Good, (26)
"I had an excellent stay here ! It was a very amazing the host is an amazing person thank you for making My stay great❤️"
United States
Shamia
Boutique Apartments Atlapa

Boutique Apartments Panamá Coco del Mar

Boutique Apartments Panamá Coco del Mar
3.5 star property
San Francisco
7.4 out of 10, Good, (152)
"Clean room good place to stay "
United States
Gideon
The price is ¥8,074
¥30,715 total
includes taxes & fees
Dec 15 - Dec 16
Boutique Apartments Panamá Coco del Mar

B&B Lodgings

B&B Lodgings
2.5 star property
24 de Diciembre
7.8 out of 10, Good, (70)
"I givethis rating of five stars because Daisy the owner, is so wonderful. I ended up checking in late. She helped me order food. She was very very accommodating. Her English is very good. The room that I stayed in was very clean and had everything that you would need. I will stay there again When I will have to stay in Panama City. The grounds are absolutely beautiful."
United States
Stephanie
The price is ¥7,476
¥8,224 total
includes taxes & fees
Dec 15 - Dec 16
B&B Lodgings

San Francisco by Wynwood House

San Francisco by Wynwood House
3.0 star property
San Francisco
9.2 out of 10, Wonderful, (56)
"Clean and walkable location"
United States
Tamera
The price is ¥22,018
¥28,141 total
includes taxes & fees
Dec 12 - Dec 13
San Francisco by Wynwood House

Dovle Residences by HMS-Preferred Member

Dovle Residences by HMS-Preferred Member
3.0 star property
San Francisco
The price is ¥30,486
¥33,535 total
includes taxes & fees
Dec 14 - Dec 15
Dovle Residences by HMS-Preferred Member

Swette Love 10 Minutes From the Airport Tocumen

Swette Love 10 Minutes From the Airport Tocumen
2.0 star property
Las Mañanitas
The price is ¥11,727
¥14,734 total
includes taxes & fees
Dec 19 - Dec 20
Swette Love 10 Minutes From the Airport Tocumen

Living 73 Panamá by Boutique Apartments

Living 73 Panamá by Boutique Apartments
3.0 star property
San Francisco
The price is ¥6,135
¥29,666 total
includes taxes & fees
Dec 22 - Dec 23
Living 73 Panamá by Boutique Apartments

Charming 3 Bedroom Apartment in San Miguelito, Panama City

Charming 3 Bedroom Apartment in San Miguelito, Panama City
2.0 star property
José Domingo Espinar
The price is ¥11,153
¥12,268 total
includes taxes & fees
Dec 19 - Dec 20
Charming 3 Bedroom Apartment in San Miguelito, Panama City

w Bright 1BR w Private Balcony in San Francisco

w Bright 1BR w Private Balcony in San Francisco
2.0 star property
San Francisco
The price is ¥14,545
¥20,624 total
includes taxes & fees
Dec 14 - Dec 15
w Bright 1BR w Private Balcony in San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top La Mesa Hotel Reviews

More cheap stays in La Mesa

Frequently asked questions

Where is the best place to stay in La Mesa?
Crowne Plaza Panama Airport by IHG, located 9.9 mi (15.9 km) from the heart of La Mesa, is a top choice for your stay based on our traveler data. Other good options for your stay in the area are Sheraton Grand Panama and Arcadia Condo Suites. See all available top hotels, or vacation rentals in La Mesa.
What are some of the best vacation home rentals in La Mesa?
LILIA HOUSE 10 MINUTES AIRPORT: Visitors like this La Mesa vacation home rental. It has air-conditioning and laundry facilities to help you feel perfectly comfortable in your new surroundings. Kitchen amenities like a stovetop and a microwave can make your vacation run smoothly. See all vacation rentals in La Mesa.
If I need to cancel my hotel reservation in La Mesa, will I receive a refund?
Yes, the majority of room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in La Mesa.
Where can I learn more about changing or cancelling my trip to La Mesa?
To access more information about updating your trip to La Mesa or cancelling it, go to https://www.expedia.com/service/.
What is staying in La Mesa like?
Visitors to La Mesa are sure to find plenty to explore and enjoy. There are 386 hotels and other accommodations in the surrounding area. Find out more about La Mesa.
What are the top places to visit in La Mesa?
Places to visit in the wider area include Metromall Panama, Los Pueblos Commercial Center, and Estadio Rommel Fernandez. You'll also find Chagres National Park and Chepo Youth Recreation Center in the area. Check out what more to see and do in Expedia's La Mesa guide.
What's the weather like in La Mesa?
The hottest months are usually April and March with an average temp of 80°F, while the coldest months are January and February with an average of 79°F. The rainiest months in La Mesa are July, August, October, and June, with each month seeing an average of 14 inches of rainfall.

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