La Mesa Vacation Rentals

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
In two months
In three months
In four months

Vacation Rentals in La Mesa

Our top choices for La Mesa vacation rentals

Dreams Playa Bonita Panama - All Inclusive

4.0 star property
7.4 out of 10, Good, (1020)
"The resort was amazing!!"
The price is ¥31,885
¥31,885 total
includes taxes & fees
Sep 28 - Sep 29
Dreams Playa Bonita Panama - All Inclusive

Hotel Riu Plaza Panama

5.0 star property
9.0 out of 10, Wonderful, (4224)
"Very convenient location, friendly staff and all around beautiful hotel."
The price is ¥16,052
¥17,657 total
includes taxes & fees
Sep 1 - Sep 2
Hotel Riu Plaza Panama

The Westin Playa Bonita Panama

5.0 star property
8.0 out of 10, Very Good, (1008)
"Excelente hotel. "
The price is ¥23,163
¥25,479 total
includes taxes & fees
Sep 9 - Sep 10
The Westin Playa Bonita Panama

Waymore Hotel Spa & Casino

4.0 star property
9.2 out of 10, Wonderful, (449)
"Thank you really like staying there first time"
The price is ¥11,910
¥13,101 total
includes taxes & fees
Aug 31 - Sep 1
Waymore Hotel Spa & Casino

Megapolis Hotel Panamá

4.5 star property
8.4 out of 10, Very Good, (1052)
"Had a wonderful stay the staff is very friendly and attentive "
The price is ¥18,389
¥20,228 total
includes taxes & fees
Aug 31 - Sep 1
Megapolis Hotel Panamá

JW Marriott Panama

5.0 star property
8.8 out of 10, Excellent, (1005)
"Excellent location, great service, beautiful views "
The price is ¥37,373
¥41,111 total
includes taxes & fees
Sep 13 - Sep 14
JW Marriott Panama

AC Hotel by Marriott Panama City

3.5 star property
8.8 out of 10, Excellent, (676)
"Great stay"
The price is ¥13,764
¥15,140 total
includes taxes & fees
Sep 5 - Sep 6
AC Hotel by Marriott Panama City

Sheraton Grand Panama

4.0 star property
8.6 out of 10, Excellent, (939)
"A great stay. "
The price is ¥19,719
¥21,691 total
includes taxes & fees
Sep 7 - Sep 8
Sheraton Grand Panama

Marriott Panama Hotel

4.0 star property
9.0 out of 10, Wonderful, (1005)
"Had an amazing stay with my family "
The price is ¥19,741
¥21,716 total
includes taxes & fees
Sep 6 - Sep 7
Marriott Panama Hotel

Crowne Plaza Panama Airport by IHG

4.0 star property
8.4 out of 10, Very Good, (2209)
"Great staff and nice rooms"
The price is ¥16,764
¥18,440 total
includes taxes & fees
Sep 25 - Sep 26
Crowne Plaza Panama Airport by IHG

Principe Hotel and Suites

3.0 star property
9.0 out of 10, Wonderful, (1452)
"Perfect stay as always!!! "
The price is ¥8,601
¥9,461 total
includes taxes & fees
Sep 15 - Sep 16
Principe Hotel and Suites

Decapolis Hotel Panama City

4.0 star property
8.6 out of 10, Excellent, (1298)
"Easy to reach and valet parking"
The price is ¥13,973
¥15,370 total
includes taxes & fees
Aug 31 - Sep 1
Decapolis Hotel Panama City

W Panama

5.0 star property
8.8 out of 10, Excellent, (1008)
"Great hotel "
The price is ¥30,469
¥33,516 total
includes taxes & fees
Sep 14 - Sep 15
W Panama

Hyatt Regency Panama City

4.5 star property
10.0 out of 10, Exceptional, (63)
"Friendly staff.. great food and in a convenient location to allow pick up for tours"
The price is ¥24,234
¥26,657 total
includes taxes & fees
Sep 14 - Sep 15
Hyatt Regency Panama City

The Executive Hotel

3.5 star property
9.2 out of 10, Wonderful, (1012)
"Wonderful place to stay"
The Executive Hotel

Waldorf Astoria Panama

5.0 star property
9.0 out of 10, Wonderful, (1004)
"Great hotel for my recent stay in Panam "
The price is ¥32,373
¥35,610 total
includes taxes & fees
Sep 20 - Sep 21
Waldorf Astoria Panama

Studio Coliving

4.5 star property
8.0 out of 10, Very Good, (464)
"I enjoyed my stay. "
The price is ¥5,816
¥6,398 total
includes taxes & fees
Aug 31 - Sep 1
Studio Coliving

Novotel Panama City

4.0 star property
9.0 out of 10, Wonderful, (1005)
"The best hotel"
The price is ¥14,558
¥16,014 total
includes taxes & fees
Aug 31 - Sep 1
Novotel Panama City

Plaza Paitilla Inn Hotel

3.5 star property
9.4 out of 10, Exceptional, (2106)
"nice place, good breakfast"
The price is ¥23,248
¥25,573 total
includes taxes & fees
Sep 2 - Sep 3
Plaza Paitilla Inn Hotel

TRYP by Wyndham Panamá Centro

3.5 star property
9.0 out of 10, Wonderful, (1011)
"Property was clean and staff specially restaurant and housekeeping very nice. "
The price is ¥12,350
¥13,585 total
includes taxes & fees
Sep 2 - Sep 3
TRYP by Wyndham Panamá Centro
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top La Mesa Hotel Reviews

Find out more about La Mesa

Find out more about La Mesa

Search for holiday rentals in La Mesa on Expedia! You can easily find your home rentals, villas, holiday apartments in La Mesa using one of the methods below:

  • View our selection of featured holiday rentals in La Mesa
  • Use the map to find apartments and other holiday homes in the La Mesa neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in La Mesa while they last

Look no further and take a look at our great range of rental properties in La Mesa!

Frequently asked questions

Are there vacation rentals in La Mesa?

Yes, we offer vacation rentals close to well known sights in La Mesa, or you can choose a more secluded option if you're looking for a relaxing stay.

What's the top vacation rental in La Mesa?

LILIA HOUSE 10 MINUTES AIRPORT: Visitors like this La Mesa vacation home rental. It has air-conditioning and laundry facilities to help you feel perfectly comfortable in your new surroundings. Kitchen amenities like a stovetop and a microwave can make your vacation run smoothly.

What’s there to see and do in La Mesa?

While exploring the area, visit family-friendly sights like Chepo Youth Recreation Center, or get outside and enjoy nature at Chagres National Park. In the larger area, you’ll find Metromall Panama and Los Pueblos Commercial Center.

What’s a vacation rental in La Mesa like?

A vacation rental is a private property you can stay in for short or long periods in La Mesa. Vacation rentals feature amenities such as hot tubs, fire pits, and patios so your stay will be comfortable. If you're concerned about a sanitized environment, vacation rentals can offer a sense of security away from public hotel elevators and busy concierge desks while still allowing you the enjoyment of travel. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is a popular option for family trips or small group gatherings.