Find hotels near Key West National Wildlife Refuge, Key West from ￥42,981

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Our top choices for Key West National Wildlife Refuge hotels

King Room D | Balcony
Simonton Court Historic Inn & Cottages

Simonton Court Historic Inn & Cottages

Simonton Court Historic Inn & Cottages
2.5 star property
Historic Seaport, 11.4 km from Key West National Wildlife Refuge
9.8 out of 10, Exceptional, (886)
"I loved staying here! The room was great and the staff was awesome! "
United States
Tiffany
The price is ￥42,133
￥47,399 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Simonton Court Historic Inn & Cottages
Garden
Douglas House

Douglas House

Douglas House
3.0 star property
Uptown - Upper Duval, 11.9 km from Key West National Wildlife Refuge
9.6 out of 10, Exceptional, (237)
"Excellent spot, I definitely recommended"
United States
Paul
The price is ￥38,264
￥47,352 total
includes taxes & fees
Jan 13 - Jan 14, 2026
Douglas House
Front of property - evening/night
Opal Key Resort & Marina, Key West

Opal Key Resort & Marina, Key West

Opal Key Resort & Marina, Key West
4.0 star property
Old Town Key West, 11 km from Key West National Wildlife Refuge
9.2 out of 10, Wonderful, (1027)
"Our stay was great!"
United States
Richard
The price is ￥65,603
￥79,970 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Opal Key Resort & Marina, Key West
Front of property
L'Habitation Guest House

L'Habitation Guest House

L'Habitation Guest House
2.5 star property
Historic Seaport, 11.2 km from Key West National Wildlife Refuge
9.4 out of 10, Exceptional, (925)
"A great no hassle stay."
United States
Gary
The price is ￥38,206
￥42,981 total
includes taxes & fees
Jan 8 - Jan 9, 2026
L'Habitation Guest House
Queen Deluxe ADA | Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds
Almond Tree Inn Hotel - Adults Only

Almond Tree Inn Hotel - Adults Only

Almond Tree Inn Hotel - Adults Only
3.5 star property
Downtown Key West, 11.8 km from Key West National Wildlife Refuge
10.0 out of 10, Exceptional, (1000)
"Great location, spotless rooms, attentive and friendly staff, great value."
United States
David
The price is ￥54,689
￥61,526 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Almond Tree Inn Hotel - Adults Only
Outdoor pool, sun loungers
Ocean Key Resort - A Noble House Resort

Ocean Key Resort - A Noble House Resort

Ocean Key Resort - A Noble House Resort
4.0 star property
Historic Seaport, 11 km from Key West National Wildlife Refuge
9.2 out of 10, Wonderful, (1004)
"Location, large rooms"
United States
george
The price is ￥69,573
￥90,424 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Ocean Key Resort - A Noble House Resort
Exterior
Orchid Key Inn - Adults Only

Orchid Key Inn - Adults Only

Orchid Key Inn - Adults Only
3.5 star property
Uptown - Upper Duval, 11.8 km from Key West National Wildlife Refuge
9.8 out of 10, Exceptional, (1001)
"Staff awesome, good breakfast great location"
United States
Carin helen
The price is ￥54,142
￥60,910 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Orchid Key Inn - Adults Only
Carriage House | Terrace/patio
The Gardens Hotel

The Gardens Hotel

The Gardens Hotel
4.0 star property
Downtown Key West, 11.6 km from Key West National Wildlife Refuge
9.8 out of 10, Exceptional, (1002)
"Loved it. The staff were very friendly and the place was classic Key West."
United States
Ben
The price is ￥63,235
￥71,139 total
includes taxes & fees
Jan 5 - Jan 6, 2026
The Gardens Hotel
View from property
Duval House

Duval House

Duval House
3.0 star property
Downtown Key West, 11.7 km from Key West National Wildlife Refuge
9.4 out of 10, Exceptional, (1002)
"Great place! "
United States
David
The price is ￥38,986
￥47,225 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Duval House
Exterior
Coco Plum Inn

Coco Plum Inn

Coco Plum Inn
3.0 star property
Downtown Key West, 11.4 km from Key West National Wildlife Refuge
9.6 out of 10, Exceptional, (470)
"The Coco Plum Inn is a wonderful place to stay. Staff is fantastic and the location is perfect. We will definitely come back and stay at the Coco Plum Inn."
United States
Brent
The price is ￥49,179
￥55,328 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Coco Plum Inn
Fountain
Island City House Hotel

Island City House Hotel

Island City House Hotel
3.0 star property
Historic Seaport, 11.7 km from Key West National Wildlife Refuge
9.6 out of 10, Exceptional, (1000)
"Excellent stay"
United States
Emily Barbara
The price is ￥62,706
￥70,544 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Island City House Hotel
11 Gecko's Garden - Adults Only | Premium bedding, pillowtop beds, individually decorated
Tropical Inn

Tropical Inn

Tropical Inn
3.5 star property
Downtown Key West, 11.7 km from Key West National Wildlife Refuge
9.6 out of 10, Exceptional, (364)
"Nice place to stay "
United States
yulio
The price is ￥43,232
￥52,551 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Tropical Inn
Premium bedding, iron/ironing board, free WiFi, bed sheets
Weatherstation Inn

Weatherstation Inn

Weatherstation Inn
2.5 star property
Truman Annex, 11 km from Key West National Wildlife Refuge
9.4 out of 10, Exceptional, (997)
"Wonderful property safe neighborhood convenient to all activities would stay here again."
United States
William
The price is ￥55,647
￥62,603 total
includes taxes & fees
Jan 26 - Jan 27, 2026
Weatherstation Inn
Outdoor pool, sun loungers
The Conch House Heritage Inn

The Conch House Heritage Inn

The Conch House Heritage Inn
3.5 star property
Old Town Key West, 12 km from Key West National Wildlife Refuge
9.8 out of 10, Exceptional, (146)
"Check in was quick, easy. "
United States
kristen
The price is ￥55,989
￥62,988 total
includes taxes & fees
Jan 4 - Jan 5, 2026
The Conch House Heritage Inn
Outdoor pool
Silver Palms Inn

Silver Palms Inn

Silver Palms Inn
3.5 star property
Old Town Key West, 12.2 km from Key West National Wildlife Refuge
9.4 out of 10, Exceptional, (1005)
"Very friendly staff, directly in City Center. "
Germany
Philip
The price is ￥37,906
￥53,213 total
includes taxes & fees
Jan 19 - Jan 20, 2026
Silver Palms Inn
Private beach, white sand, sun loungers, beach umbrellas
Pier House Resort & Spa

Pier House Resort & Spa

Pier House Resort & Spa
4.0 star property
Historic Seaport, 11 km from Key West National Wildlife Refuge
9.0 out of 10, Wonderful, (1010)
"All accommodations were outstanding!"
United States
Bob
Pier House Resort & Spa
Exterior
La Concha Key West, Autograph Collection

La Concha Key West, Autograph Collection

La Concha Key West, Autograph Collection
4.0 star property
Historic Seaport, 11.3 km from Key West National Wildlife Refuge
9.0 out of 10, Wonderful, (298)
"Very nice staff! Clean hotel! "
United States
Tabitha Hall
The price is ￥62,471
￥75,564 total
includes taxes & fees
Jan 5 - Jan 6, 2026
La Concha Key West, Autograph Collection
Outdoor pool, sun loungers
The Mermaid & Alligator

The Mermaid & Alligator

The Mermaid & Alligator
3.5 star property
Old Town Key West, 12.1 km from Key West National Wildlife Refuge
9.8 out of 10, Exceptional, (276)
"Great place"
United States
Carol A
The Mermaid & Alligator
Exterior
The Grand Guesthouse

The Grand Guesthouse

The Grand Guesthouse
2.5 star property
Old Town Key West, 12.5 km from Key West National Wildlife Refuge
9.6 out of 10, Exceptional, (1000)
"Great stay"
United States
Ginger
The Grand Guesthouse
Outdoor pool
The Garden House

The Garden House

The Garden House
3.0 star property
Historic Seaport, 11.5 km from Key West National Wildlife Refuge
9.2 out of 10, Wonderful, (668)
"It a small convenient location and walkable to great areas. "
United States
Manuel
The price is ￥39,612
￥47,930 total
includes taxes & fees
Jan 4 - Jan 5, 2026
The Garden House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Key West National Wildlife Refuge Hotel Reviews

Hyatt Centric Key West Resort and Spa

Hyatt Centric Key West Resort and Spa

10/10 Excellent
"We didn't know there was breakfast until this survey! How did we miss it? The pet friendliness was great. Our dog was happy about the grass out front and the availability of ice. She loves ice."
Eric 2-night trip
Posted 3 days ago
Hyatt Centric Key West Resort and Spa

Hotels near other Key West National Wildlife Refuge attractions

Truman Beach

Why not spend a lazy afternoon at Truman Beach during your trip to Key West? Stroll along the seaside or discover the area's beautiful sunsets.
See properties
Fort Zachary Taylor Park, Key West. State Park in Florida, USA., Shutterstock ID 761867707, Purchase Order: SP-1891 Wave 0, Client/Licensee: Hotels.com

Fort Zachary Taylor Historic State Park

4.4/5 (1,160 reviews)
The displays of old weapons and interpretive panels in a fort at the heart of the southernmost state park in the continental U.S. provide information about the Civil War.
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Frequently asked questions

What's the area like around Key West National Wildlife Refuge?
Key West National Wildlife Refuge is located in an area of Key West known for its bar scene, biking, and lively festivals. Key West is home to 2776 hotels and other accommodations, so you can find something that's perfect for your stay.
What's the best place to stay close to Key West National Wildlife Refuge?
Pier House Resort & Spa is one of the top choices for your stay based on our traveler data, and this resort offers a full-service spa and a private beach. You'll find it 6.9 mi (11 km) from Key West National Wildlife Refuge. Other good options around the area include Hyatt Centric Key West Resort and Spa and Ocean Key Resort - A Noble House Resort.
If I need to cancel the hotel reservation for my stay near Key West National Wildlife Refuge, will I receive a refund?
Yes, most hotel room reservations are refundable if you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, it may still be possible to cancel it and receive a refund within 24 hours of booking. Plug in your dates, click on "Search", then use the "fully refundable" filter to review the best options available near Key West National Wildlife Refuge.
Where can I learn more about changing or cancelling my trip in the area near Key West National Wildlife Refuge?
For additional details about picking new dates or cancelling your stay near Key West National Wildlife Refuge, go to https://www.expedia.com/service/.