The Best Hotels Closest to Key West National Wildlife Refuge in Key West for 2026

Our top choices for Key West National Wildlife Refuge hotels

Queen Deluxe ADA | Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds

Almond Tree Inn Hotel - Adults Only

Downtown Key West, 11.8 km from Key West National Wildlife Refuge

Renee

￥41,015 total

includes taxes & fees

May 25 - May 26

Douglas House - Adults Only

Uptown - Upper Duval, 11.8 km from Key West National Wildlife Refuge

Scott

￥29,445 total

includes taxes & fees

Jun 4 - Jun 5

Orchid Key Inn - Adults Only

Uptown - Upper Duval, 11.8 km from Key West National Wildlife Refuge

Michael

￥41,246 total

includes taxes & fees

May 25 - May 26

Outdoor pool, free cabanas, sun loungers

Ocean Key Resort - A Noble House Resort

Historic Seaport, 11 km from Key West National Wildlife Refuge

Terrie

￥54,795 total

includes taxes & fees

Jun 23 - Jun 24

Queen with Pool View | Minibar, in-room safe, individually decorated, individually furnished

Simonton Court Historic Inn & Cottages

Historic Seaport, 11.4 km from Key West National Wildlife Refuge

Olha

￥26,149 total

includes taxes & fees

May 25 - May 26

Premium bedding, iron/ironing board, free WiFi, bed sheets

Weatherstation Inn

Truman Annex, 11 km from Key West National Wildlife Refuge

A. Elise

￥35,636 total

includes taxes & fees

May 25 - May 26

The Gardens Hotel

Downtown Key West, 11.6 km from Key West National Wildlife Refuge

Markus

￥36,768 total

includes taxes & fees

Jun 23 - Jun 24

L'Habitation Guest House

Historic Seaport, 11.2 km from Key West National Wildlife Refuge

Michael

￥24,015 total

includes taxes & fees

May 25 - May 26

Duval House

Downtown Key West, 11.7 km from Key West National Wildlife Refuge

gerald

￥30,105 total

includes taxes & fees

May 26 - May 27

Southernmost House - Adult Exclusive

Uptown - Upper Duval, 12.1 km from Key West National Wildlife Refuge

BOBBY J.

￥54,385 total

includes taxes & fees

Jun 7 - Jun 8

Cigar House King Suite w/ Poolside porch | Balcony view

Island City House Hotel

Historic Seaport, 11.7 km from Key West National Wildlife Refuge

Michael

￥39,447 total

includes taxes & fees

Jun 7 - Jun 8

Duval Inn

Downtown Key West, 11.6 km from Key West National Wildlife Refuge

Terry

￥35,718 total

includes taxes & fees

May 28 - May 29

The Marquesa Hotel

Old Town Key West, 11.5 km from Key West National Wildlife Refuge

Julian

￥60,708 total

includes taxes & fees

Jun 16 - Jun 17

Private beach, white sand, sun loungers, beach umbrellas

Pier House Resort & Spa

Historic Seaport, 11 km from Key West National Wildlife Refuge

Barry

￥56,102 total

includes taxes & fees

May 31 - Jun 1

11 Gecko's Garden - Adults Only | Premium bedding, pillowtop beds, individually decorated

Tropical Inn

Downtown Key West, 11.7 km from Key West National Wildlife Refuge

Akhenaton

￥46,031 total

includes taxes & fees

May 25 - May 26

Opal Key Resort & Marina, Key West

Old Town Key West, 11 km from Key West National Wildlife Refuge

Theresa

￥52,651 total

includes taxes & fees

May 26 - May 27

Westwinds Inn

Historic Seaport, 11.9 km from Key West National Wildlife Refuge

michael

￥36,263 total

includes taxes & fees

Jun 7 - Jun 8

Authors of Key West Guest House

The Meadows, 12.4 km from Key West National Wildlife Refuge

Royston

￥24,015 total

includes taxes & fees

May 27 - May 28

Hyatt Centric Key West Resort and Spa

Historic Seaport, 11.3 km from Key West National Wildlife Refuge

Lynn

￥49,784 total

includes taxes & fees

May 25 - May 26

Heron House - Adult Only

Downtown Key West, 11.5 km from Key West National Wildlife Refuge

Janet

￥26,559 total

includes taxes & fees

May 25 - May 26

View all properties

Compare popular hotels close to Key West National Wildlife Refuge

Property	Star rating	Guest rating
Almond Tree Inn Hotel - Adults Only	3.5 star property	10.0 Exceptional 1,003 reviews	View
Douglas House - Adults Only	3.0 star property	9.6 Exceptional 390 reviews	View
Orchid Key Inn - Adults Only	3.5 star property	9.8 Exceptional 1,001 reviews	View
Ocean Key Resort - A Noble House Resort	4.0 star property	9.2 Wonderful 1,005 reviews	View
Simonton Court Historic Inn & Cottages	2.5 star property	9.8 Exceptional 964 reviews	View

Top Key West National Wildlife Refuge Hotel Reviews

Southernmost Beach Resort and Guesthouses

8/10 Good

"Had a great time. Everything was great and people were very helpful and friendly."

Opal Key Resort & Marina, Key West

10/10 Excellent

"Beautiful property with very clean, spacious rooms with good lighting and well designed bathrooms. Bed was a little soft for my liking. Small balcony facing ocean but sufficient and had sunset view. Although cruise ships dock directly behind the hotel blocking views, they are only in port from 8am-4pm. Since we were not in the room during those hours it didn't bother us. I would stay here again."

Pier House Resort & Spa

8/10 Good

"Hotel was nice but for $700+ a night I expected much more. The room needed repairs and the building stayed in had no elevator. You could tell they replaced the floor in the room but didn’t finish the transitions and the area rug was dirty. The room was big and had juliet balcony's which was nice but the lock was broke on one so it wouldn’t open. The staff were great and the bartenders at the pool bar were awesome. The Cobb salad was delicious!"

Weatherstation Inn

10/10 Excellent

"A lovely old building with very comfortable rooms. The bed was huge. The bathroom was lovely, with two shower heads. Breakfast items were placed in the hallway, which included fruit, pastries and cereal bars. There was access to a coffee machine at all times, although would be lovely to have more vegan and dairy-free options available! The AC unfortunately couldn't get below 70°f, which meant we struggled with the heat a little, but otherwise the property was charming and the staff were very welcoming. Would love to stay here again."

Pegasus International Hotel

8/10 Good

"Room was nice and clean but small. Desk is open limited hours so schedule your arrival accordingly. Parking is limited and a block away but doable. Facility overall was very nice, but be prepared: the bathrooms are rediculously small. If you're a very large person you may want to rethink a stay here. In our room, if you're sitting on the toilet, your head is hitting the wall, it's that close to the wall. And the gap between the glass shower wall and the rear wall of the shower is only 18", so if you're big you may have a hard time even getting into the shower. At least that's how it was in our room."

Hotels near other Key West National Wildlife Refuge attractions

Truman Beach

Why not spend a lazy afternoon at Truman Beach during your trip to Key West? Stroll along the seaside or discover the area's beautiful sunsets.

See properties

Frequently asked questions

What's the area like around Key West National Wildlife Refuge?

Key West National Wildlife Refuge is located in an area of Key West known for its bar scene, biking, and lively festivals. Key West is home to 2685 hotels and other accommodations, so you can find something that's perfect for your stay.

What's the best place to stay close to Key West National Wildlife Refuge?

Opal Key Resort & Marina, Key West is one of the top choices for your stay based on our traveler data, and this hotel offers a marina and 3 bars. You'll find it 6.8 mi (11 km) from Key West National Wildlife Refuge. Other good options around the area include Pier House Resort & Spa and La Concha Key West, Autograph Collection.

If I need to cancel the hotel reservation for my stay near Key West National Wildlife Refuge, will I receive a refund?

Yes, most hotel room reservations are refundable if you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, it may still be possible to cancel it and receive a refund within 24 hours of booking. Plug in your dates, click on "Search", then use the "fully refundable" filter to review the best options available near Key West National Wildlife Refuge.

Where can I learn more about changing or cancelling my trip in the area near Key West National Wildlife Refuge?

For additional details about picking new dates or cancelling your stay near Key West National Wildlife Refuge, go to https://www.expedia.com/service/.

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Our top choices for Key West National Wildlife Refuge hotels

Almond Tree Inn Hotel - Adults Only

Douglas House - Adults Only

Orchid Key Inn - Adults Only

Ocean Key Resort - A Noble House Resort

Simonton Court Historic Inn & Cottages

Weatherstation Inn

The Gardens Hotel

L'Habitation Guest House

Duval House

Southernmost House - Adult Exclusive

Island City House Hotel

Duval Inn

The Marquesa Hotel

Pier House Resort & Spa

Tropical Inn

Opal Key Resort & Marina, Key West

Westwinds Inn

Authors of Key West Guest House

Hyatt Centric Key West Resort and Spa

Heron House - Adult Only

Compare popular hotels close to Key West National Wildlife Refuge

Top Key West National Wildlife Refuge Hotel Reviews

Southernmost Beach Resort and Guesthouses

Hotels near other Key West National Wildlife Refuge attractions

Truman Beach

Frequently asked questions