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Find hotels near Florida Keys National Marine Sanctuary, Key West from ¥15,862

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Aug 21 - Aug 22
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Our top choices for Florida Keys National Marine Sanctuary hotels

1. Almond Tree Inn Hotel - Adults Only

Almond Tree Inn Hotel - Adults Only
Downtown Key West, 0.9 km from Florida Keys National Marine Sanctuary
United States
Michelle
¥29,209
¥32,860 total
includes taxes & fees
Aug 23 - Aug 24
Almond Tree Inn Hotel - Adults Only

2. Key West Villas

Key West Villas
Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary
United States
Margaret
¥41,345
¥46,514 total
includes taxes & fees
Sep 3 - Sep 4
Key West Villas

3. The Mermaid & Alligator

The Mermaid & Alligator
Old Town Key West, 1.2 km from Florida Keys National Marine Sanctuary
United States
Johnny
¥31,151
¥35,045 total
includes taxes & fees
Aug 24 - Aug 25
The Mermaid & Alligator

4. Orchid Key Inn - Adults Only

Orchid Key Inn - Adults Only
Uptown - Upper Duval, 0.8 km from Florida Keys National Marine Sanctuary
United States
Nicholas
¥29,209
¥32,860 total
includes taxes & fees
Aug 23 - Aug 24
Orchid Key Inn - Adults Only

5. H2O Suites - Adults Only

H2O Suites - Adults Only
Uptown - Upper Duval, 1.1 km from Florida Keys National Marine Sanctuary
United States
Shermeka
¥44,350
¥60,624 total
includes taxes & fees
Sep 7 - Sep 8
H2O Suites - Adults Only

6. The Marquesa Hotel

The Marquesa Hotel
Old Town Key West, 1 km from Florida Keys National Marine Sanctuary
United States
Darrell
¥35,919
¥49,352 total
includes taxes & fees
Sep 8 - Sep 9
The Marquesa Hotel

7. Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly

Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly
Old Town Key West, 1.7 km from Florida Keys National Marine Sanctuary
United States
Jaime
¥16,079
¥24,107 total
includes taxes & fees
Aug 22 - Aug 23
Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly

8. Duval House

Duval House
Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary
United States
Melissa
¥16,214
¥21,659 total
includes taxes & fees
Aug 31 - Sep 1
Duval House

9. Island City House Hotel

Island City House Hotel
Historic Seaport, 1.2 km from Florida Keys National Marine Sanctuary
United States
Paul
¥23,224
¥26,128 total
includes taxes & fees
Aug 25 - Aug 26
Island City House Hotel

10. The Grand Guesthouse

The Grand Guesthouse
Old Town Key West, 1.6 km from Florida Keys National Marine Sanctuary
United States
Travis
¥21,520
¥28,184 total
includes taxes & fees
Aug 23 - Aug 24
The Grand Guesthouse

11. Santa Maria Suites

Santa Maria Suites
Uptown - Upper Duval, 1.3 km from Florida Keys National Marine Sanctuary
United States
Nila
¥44,350
¥60,624 total
includes taxes & fees
Aug 23 - Aug 24
Santa Maria Suites

12. Silver Palms Inn & Historic Homes

Silver Palms Inn & Historic Homes
Old Town Key West, 1.3 km from Florida Keys National Marine Sanctuary
United States
Shawn
¥11,763
¥23,963 total
includes taxes & fees
Sep 1 - Sep 2
Silver Palms Inn & Historic Homes

13. Marrero's Guest Mansion

Marrero's Guest Mansion
Downtown Key West, 0.7 km from Florida Keys National Marine Sanctuary
United States
Michael
¥34,812
¥39,164 total
includes taxes & fees
Aug 31 - Sep 1
Marrero's Guest Mansion

14. Ambrosia Key West

Ambrosia Key West
Old Town Key West, 1 km from Florida Keys National Marine Sanctuary
United States
Jenina
¥29,914
¥33,653 total
includes taxes & fees
Sep 1 - Sep 2
Ambrosia Key West

15. Authors of Key West Guest House

Authors of Key West Guest House
The Meadows, 1.8 km from Florida Keys National Marine Sanctuary
United States
Kasi
¥14,098
¥15,862 total
includes taxes & fees
Aug 23 - Aug 24
Authors of Key West Guest House

16. Heron House - Adult Only

Heron House - Adult Only
Downtown Key West, 0.9 km from Florida Keys National Marine Sanctuary
United States
Lindsay
¥15,594
¥22,751 total
includes taxes & fees
Aug 23 - Aug 24
Heron House - Adult Only

17. Opal Key Resort & Marina, Key West

Opal Key Resort & Marina, Key West
Old Town Key West, 0.9 km from Florida Keys National Marine Sanctuary
United States
Melissa
¥41,171
¥52,578 total
includes taxes & fees
Aug 23 - Aug 24
Opal Key Resort & Marina, Key West

18. Alexander Palms Court

Alexander Palms Court
Casa Marina, 1.4 km from Florida Keys National Marine Sanctuary
United States
Julianne
¥22,175
¥24,947 total
includes taxes & fees
Aug 24 - Aug 25
Alexander Palms Court

19. Caribbean House

Caribbean House
Bahama Village, 0.5 km from Florida Keys National Marine Sanctuary
United States
William
¥19,452
¥25,858 total
includes taxes & fees
Aug 24 - Aug 25
Caribbean House

20. The Marker Key West Harbor Resort

The Marker Key West Harbor Resort
Historic Seaport, 1.3 km from Florida Keys National Marine Sanctuary
United States
Danny Lee
¥26,452
¥39,726 total
includes taxes & fees
Sep 1 - Sep 2
The Marker Key West Harbor Resort
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Compare popular hotels close to Florida Keys National Marine Sanctuary

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Queen Deluxe ADA
Almond Tree Inn Hotel - Adults Only
10.0
Exceptional
1,020 reviews
View
Front of property
Key West Villas
9.8
Exceptional
275 reviews
View
Audubon Room - Adult Exclusive | Terrace/patio
The Mermaid & Alligator
9.8
Exceptional
313 reviews
View
Property grounds
Orchid Key Inn - Adults Only
9.8
Exceptional
1,017 reviews
View
Deluxe Suite, 1 King Bed, Private Pool | View from room
H2O Suites - Adults Only
9.8
Exceptional
641 reviews
View

Top Florida Keys National Marine Sanctuary Hotel Reviews

Pier House Resort & Spa

Pier House Resort & Spa

8/10 Good
"This place was great! The rooms are dated and don't have smart TVs, so you can't catch up on anything streaming at night, but the private beach and pool area make up for it! Everyone was very nice. I'll say we brought our 7 year old and he was one of maybe 5 children there so it's not very child friendly but he had a great time."
Anastasia 4-night trip
Posted 2 hours ago
Pier House Resort & Spa
Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

8/10 Good
"Parking and resort fees expensive for what you get."
Lorie 5-night trip
Posted 20 hours ago
Southernmost Beach Resort and Guesthouses
Duval House

Duval House

10/10 Excellent
"Fantastic location with parking. The property is like no other on Duval."
Thomas 2-night trip
Posted 22 hours ago
Duval House
Southwinds Motel

Southwinds Motel

10/10 Excellent
"This was day 16 of a US road trip and this was BY FAR my favorite stay. 1 block away from Duval St. Free drink tickets. Great bed and pillows. Microwave, fridge. Everything was GREAT! Only downside was we went to bed at 10 and the nearby bar was still playing loud live music, however the loud AC unit drowned it out lol. Ice machine could use something to make it look cleaner/better, but still produced ice just fine. Breakfast was pretty much entirely bread/muffins/cereal/bagels. Parking was not free, which is also a bummer. But being so close to everything we wanted made up for it."
Riley 1-night trip
Posted 1 day ago
Southwinds Motel
La Concha Key West, Autograph Collection

La Concha Key West, Autograph Collection

10/10 Excellent
"We had a wonderful stay at La Concha Hotel in Key West! The location on Duval Street was one of the biggest highlights..it was within perfect walking distance of so many of Key West’s attractions, restaurants, bars, and things to do, which made exploring the area incredibly convenient. Having onsite parking was also a huge benefit, especially in Key West where parking can be difficult to find. The hotel bar was excellent, and the staff throughout the hotel were incredibly friendly and welcoming. Overall, La Concha was a great choice for a Key West stay, especially if you want to be right in the heart of everything!"
Janet 1-night trip
Posted 2 days ago
La Concha Key West, Autograph Collection
Tranquility Guest House

Tranquility Guest House

10/10 Excellent
"We had a great stay. If you're looking for a quiet place of of Duval, I highly recommend this place. It's not a fancy place but the rooms are clean, the beds are comfortable and the pool is lovely. The location is fantastic! Walking distance to several nice restaurants and bars. Stores nearby. The hosts communicate very well. Anything we needed, they were on it right away with a text and let us know when to expect them. We will be booking here for our future stays."
Dianna 7-night trip
Posted 3 days ago
Tranquility Guest House
Opal Key Resort & Marina, Key West

Opal Key Resort & Marina, Key West

10/10 Excellent
"This hotel was really truly excellent. We thoroughly enjoyed our stay."
Melissa 3-night trip
Posted 6 days ago
Opal Key Resort & Marina, Key West
Weatherstation Inn

Weatherstation Inn

10/10 Excellent
"Nice place"
daniel 2-night trip
Posted 6 days ago
Weatherstation Inn
Beach Paradise in the Keys! Location! Location! 2 Blocks to Duval St

Beach Paradise in the Keys! Location! Location! 2 Blocks to Duval St

10/10 Excellent
"The Host communicated with us and made the check-in process very easy. The property has been updated and is very nice."
DAN D. 7-night trip
Posted 2 months ago
Beach Paradise in the Keys! Location! Location! 2 Blocks to Duval St

Other attractions near Florida Keys National Marine Sanctuary

A yellow exhibit labeled 'NOAA's AQUARIUS UNDERSEA LAB' with a circular window and a door.

Florida Keys Eco - Discovery Center

8.8/10 (128 reviews)
Learn about the area’s important marine ecology at this comprehensive attraction that addresses global environmental concerns, interesting for visitors of all ages.
See properties
A brick corridor with arched ceilings and benches.

Fort Zachary Taylor Historic State Park

9.0/10 (4,544 reviews)
The displays of old weapons and interpretive panels in a fort at the heart of the southernmost state park in the continental U.S. provide information about the Civil War.
See properties
A wooden signpost with directional arrows pointing to various cities and their distances.
Photo by Martin Pettersson

Truman Beach

Why not spend a lazy afternoon at Truman Beach during your trip to Key West? Stroll along the seaside or discover the area's beautiful sunsets.
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The Monroe County Courthouse with a clock tower, surrounded by trees and a clear blue sky.

Jackson Square

8.8/10 (110 reviews)
You can learn about the history of Key West with a stop at Jackson Square. Stroll along the beautiful beaches or discover the area's beautiful sunsets.
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Coffee Butler Amphitheater

You can enjoy a show at Coffee Butler Amphitheater during your trip to Key West. Discover the area's lively bars and its great live music.
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USCGC Ingham Maritime Museum

You can spend an afternoon exploring the galleries in USCGC Ingham Maritime Museum during your trip to Key West.
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Truman Waterfront Park

You can take time to visit Truman Waterfront Park during your travels to Key West. Discover the area's lively bars and its great live music.
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We Cycle Key West

You can search for that perfect souvenir at We Cycle Key West during your trip to Key West.
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Frequently asked questions

What's the area like around Florida Keys National Marine Sanctuary?
Florida Keys National Marine Sanctuary is located in an area of Key West known for its beautiful ocean views, biking, and lively festivals. If you're looking for a convenient place to stay, check out the 1492 hotels and other accommodations you'll find within a mile.
Where is the best place to stay close to Florida Keys National Marine Sanctuary?
Adjacent to Florida Keys National Marine Sanctuary, Tranquility Guest House is one of the top choices for your stay based on our traveler data, and this hotel offers an outdoor pool and free WiFi. Other good choices close by include Southernmost Beach Resort and Guesthouses and La Concha Key West, Autograph Collection.
How many hotels will I be able to find near Florida Keys National Marine Sanctuary?
Expedia has 1492 hotels and other accommodations within a mile from Florida Keys National Marine Sanctuary.
If I need to cancel the hotel reservation for my stay near Florida Keys National Marine Sanctuary, will I receive a refund?
Yes, most hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and be given a refund within 24 hours of your booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to review the best options available near Florida Keys National Marine Sanctuary.
Where can I learn more about changing or cancelling my trip in the area near Florida Keys National Marine Sanctuary?
To find more details about updating your stay near Florida Keys National Marine Sanctuary or cancelling it, head over to our customer service page.
What can I see and do near Florida Keys National Marine Sanctuary?
Florida Keys Eco - Discovery Center, Harry S. Truman Little White House, and Key West Lighthouse and Keeper's Quarters Museum feature captivating exhibits. Fort Zachary Taylor Historic State Park, Ernest Hemingway Home and Museum, and Key West Historic Seaport are some of the notable landmarks to see in the area. You can watch performances at Waterfront Playhouse, Coffee Butler Amphitheater, and Key West Film Society if you're interested in local theater.

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