Large rocks and a sandy beach with sparse vegetation.

Find hotels in Isla Santa María from ¥6,313

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Check prices for these dates

Tonight
Aug 30 - Aug 31
Tomorrow
Aug 31 - Sep 1
Next weekend
Sep 4 - Sep 6
In two weeks
Sep 11 - Sep 13

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Our top choices for Isla Santa María hotels

1. White House Galapagos

White House Galapagos
Puerto Ayora
Canada
Christianne
¥5,763
¥8,068 total
Sep 2 - Sep 3
White House Galapagos

2. Hostal Costa del Pacifico

Hostal Costa del Pacifico
Puerto Ayora
United States
Anonymous traveler
¥6,973
¥6,973 total
Sep 5 - Sep 6
Hostal Costa del Pacifico

3. Carpao Lodge

Carpao Lodge
Puerto Ayora
United Kingdom
Richard
¥4,398
¥4,398 total
Sep 18 - Sep 19
Carpao Lodge

4. Posada del Mar

Posada del Mar
Puerto Ayora
United States
Grace
¥11,664
¥11,664 total
Sep 1 - Sep 2
Posada del Mar

5. Hostal North Seymour

Hostal North Seymour
Puerto Ayora
United States
Maria del Pilar
¥8,760
¥8,760 total
Aug 31 - Sep 1
Hostal North Seymour

6. Casa del Lago Lodging House

Casa del Lago Lodging House
Puerto Ayora
United States
Jingyuan
¥9,396
¥10,805 total
Aug 31 - Sep 1
Casa del Lago Lodging House

7. HOTEL CROSSMAN

HOTEL CROSSMAN
Puerto Ayora
Canada
PENGFEI
¥10,457
¥10,457 total
Sep 7 - Sep 8
HOTEL CROSSMAN

8. La k-leta boutique guest house

La k-leta boutique guest house
Puerto Ayora
¥15,209
¥16,730 total
Aug 31 - Sep 1
La k-leta boutique guest house

9. Hostal Sir Francis Drake

Hostal Sir Francis Drake
Puerto Ayora
United States
Dr Farkas
¥8,673
¥8,673 total
Sep 6 - Sep 7
Hostal Sir Francis Drake

10. Hostal Casa Cascada

Hostal Casa Cascada
Puerto Ayora
¥2,631
¥6,313 total
Sep 30 - Oct 1
Hostal Casa Cascada

11. Hotel La Casa de Judy

Hotel La Casa de Judy
Puerto Ayora
Canada
Alexandra
¥10,172
¥12,573 total
Sep 8 - Sep 9
Hotel La Casa de Judy

12. Hotel Brisas Del Pacifico

Hotel Brisas Del Pacifico
Puerto Ayora
United States
claudia
¥7,781
¥7,781 total
Aug 31 - Sep 1
Hotel Brisas Del Pacifico

13. Capitan Max B&B

Capitan Max B&B
Puerto Ayora
Canada
Christie
¥11,765
¥11,765 total
Sep 9 - Sep 10
Capitan Max B&B

14. Ariana´S Galapagos Hostal

Ariana´S Galapagos Hostal
Puerto Ayora
Canada
Alexander
¥8,029
¥8,029 total
Aug 31 - Sep 1
Ariana´S Galapagos Hostal

15. Ocean Dreams Galapagos

Ocean Dreams Galapagos
Puerto Ayora
United States
David
¥10,777
¥16,540 total
Aug 31 - Sep 1
Ocean Dreams Galapagos

16. Hotel Palace Galapagos

Hotel Palace Galapagos
Puerto Ayora
United States
Tomoko
¥11,088
¥11,088 total
Sep 15 - Sep 16
Hotel Palace Galapagos

17. Galapagos Verde Azul

Galapagos Verde Azul
Puerto Ayora
Canada
sierra
¥13,551
¥13,551 total
Sep 6 - Sep 7
Galapagos Verde Azul

18. Suites

Suites
Puerto Ayora
United States
Judy
¥12,060
¥13,341 total
Aug 31 - Sep 1
Suites

19. Galapagos Native

Galapagos Native
Puerto Ayora
United States
Harry
¥18,154
¥18,154 total
Aug 31 - Sep 1
Galapagos Native

20. Hotel el descanso del Guia

Hotel el descanso del Guia
Puerto Ayora
United States
Keathan B.
¥11,172
¥11,172 total
Sep 30 - Oct 1
Hotel el descanso del Guia
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Stay near popular Isla Santa María attractions

A sea turtle swimming underwater.
Photo by Tove Martin

Post Office Bay

Commune with nature and explore the great outdoors at Post Office Bay during your travels in Isla Santa María. While you're in the area, wander around the natural setting.
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Two seals resting on a sandy beach with a rocky shoreline and a sunset in the background.
Photo by Delen Wong

Punta Suarez

Explore the great outdoors at Punta Suarez, a lovely green space in Isla Santa María. Wander the seaside and white-sand beaches while you're in the area.
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Learn more about Isla Santa María

Head to sights like Galápagos National Park and Post Office Bay as you discover Isla Santa María.

See all hotels in Isla Santa María
A beach with sea lions resting on the sand and a cruise ship in the distance.
Photo by Delen Wong

Top Isla Santa María Hotel Reviews

Angermeyer Waterfront Inn

Angermeyer Waterfront Inn

10/10 Excellent
"The staff is amazing! They are so helpful including Maria Soledad and Rebeca. The location is truly unique, A water taxi ride is needed to get to the hotel from downtown. It's fun and easy and only cost $1 per person. 6 options with included breakfast are all excellent. Recommend booking with breakfast."
Matt 3-night trip
Posted 1 hour ago
Angermeyer Waterfront Inn
Hotel Cucuve

Hotel Cucuve

10/10 Excellent
"Everything was up to expectations, great stay!"
Sylvia 4-night trip
Posted 1 day ago
Hotel Cucuve
Hotel La Casa de Judy

Hotel La Casa de Judy

10/10 Excellent
"This hotel was a great choice. Close enough to walk into town, great views, clean room (including bathroom) and friendly and helpful staff."
Alexandra 1-night trip
Posted 2 days ago
Hotel La Casa de Judy
Hotel Ninfa

Hotel Ninfa

10/10 Excellent
"Staff was really friendly and helpful"
Kleber 4-night trip
Posted 7 days ago
Hotel Ninfa
Hotel Fiesta

Hotel Fiesta

10/10 Excellent
"Clean, safe, very friendly staff. close to port and main shopping/dining. lovely pool, affordable drinks at bar and good breakfast."
Daniel 2-night trip
Posted 8 days ago
Hotel Fiesta
Fernandina Hotel & Spa Galápagos

Fernandina Hotel & Spa Galápagos

8/10 Good
"Everything was convenient and easy. Staff were very helpful. All went well"
Prithvish 3-night trip
Posted 10 days ago
Fernandina Hotel & Spa Galápagos
Hotel Coloma Galapagos

Hotel Coloma Galapagos

8/10 Good
"quirky simple hotel. Owner helped us carry the luggage up the stairs. it's on Baltra Ave near more locally owned businesses but close to the Malecon (walkway along the shore) and all the tourist places. Very friendly staff (Sandra & Magali) who cooked a nice breakfast for us every morning. Good reasonably priced seafood meal down the street at the Rustica. We stopped in the Bike shop also down the street about renting E-bikes and received some more restaurant suggestions. People said Buenas Dias to us in the street."
jack 3-night trip
Posted 11 days ago
Hotel Coloma Galapagos
Galapagos Verde Azul

Galapagos Verde Azul

8/10 Good
"Our room was spotless. The floors were mopped everyday. All of the wildlife in the area was magical."
Stan 6-night trip
Posted 12 days ago
Galapagos Verde Azul
Hotel el descanso del Guia

Hotel el descanso del Guia

10/10 Excellent
"Really quirky hotel which we loved. Very central and staff were great."
Gordon 3-night trip
Posted 2 weeks ago
Hotel el descanso del Guia

More cheap stays in Isla Santa María

Hotel Brisas Del Pacifico

Hotel Brisas Del Pacifico

General Rodriguez Puerto Ayora
¥7,781
¥7,781 total
Aug 31 - Sep 1
7.6/10 Good! (82 reviews)
Hotel Brisas Del Pacifico
White House Galapagos

White House Galapagos

Calle Roberto Schiess e Isla Duncan Puerto Ayora Santa Cruz
¥5,763
¥8,068 total
Sep 2 - Sep 3
9/10 Wonderful! (106 reviews)
White House Galapagos
Hostal Sir Francis Drake

Hostal Sir Francis Drake

Av. Baltra y Charles Binford Puerto Ayora Galapagos
¥8,673
¥8,673 total
Sep 6 - Sep 7
Hostal Sir Francis Drake
Lonesome George Ecolodge

Lonesome George Ecolodge

Avenida Cucuve S/N and Floreana Puerto Ayora Santa Cruz
¥16,009
¥16,009 total
Sep 2 - Sep 3
Lonesome George Ecolodge
Acacia Galapagos Boutique Hotel

Acacia Galapagos Boutique Hotel

C/ Floreana Y Matazarnos Puerto Ayora Islas Galápagos
¥30,721
¥30,721 total
Sep 7 - Sep 8
10/10 Exceptional! (42 reviews)
Acacia Galapagos Boutique Hotel
El Barranco Galapagos

El Barranco Galapagos

Los colonos Puerto Ayora Galapagos
¥32,153
¥32,153 total
Sep 6 - Sep 7
El Barranco Galapagos

Frequently asked questions

Where is the best place for a stay in Isla Santa María?
Located 38.3 mi (61.7 km) from the heart of Isla Santa María, Hotel Fiesta is a top choice for your stay based on our traveler data. Other good choices for your trip to the area are Finch Bay Galapagos Hotel and Maidith Galapagos Inn. See all available top hotels, or vacation rentals in Isla Santa María.
What are some of the best vacation rentals that Isla Santa María has to offer?
Villa Galapagos: This vacation home rental near Isla Santa María is located near the beach and offers a private yard, air-conditioning, and daily housekeeping to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave. See all vacation rentals in Isla Santa María.
If I need to cancel my hotel reservation in Isla Santa María, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Isla Santa María.
Where can I learn more about changing or cancelling my trip to Isla Santa María?
For more details about updating your trip to Isla Santa María or cancelling it, click here.
What is staying in Isla Santa María like?
Travelers to Isla Santa María will find plenty to explore and enjoy. There are 216 hotels and other accommodations in larger region. Find out more about Isla Santa María.
What should I see while I'm in Isla Santa María?
Favorite places to visit include Galápagos National Park, Post Office Bay, and Punta Suarez. Check out what more to see and do in Expedia's Isla Santa María guide.
What's the weather like in Isla Santa María?
The hottest months are usually March and February with an average temp of 79°F, while the coldest months are September and October with an average of 72°F. Average annual precipitation for Isla Santa María is 13 inches.