A river with a bridge, a town, and a forested hillside.

Find Resorts & Hotels with Spas in Hannibal, MO

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Check availability on Hannibal Resorts & Hotels with Spas

Tonight
Oct 20 - Oct 21
Tomorrow
Oct 21 - Oct 22
This weekend
Oct 23 - Oct 25
Next weekend
Oct 30 - Nov 1

Our top choices for Hannibal hotels with a spa

A wooden interior with a hot tub, a wheelchair-accessible bench, and a window.
A hotel room with a bed, a sofa, a desk, and a lamp.
An indoor swimming pool with wooden walls, a tiled floor, and a sign indicating no diving is allowed.
A Comfort Inn & Suites hotel with a stone facade, a covered entrance, and a clear blue sky.

1. Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
Hannibal
  • Serene spa sanctuary awaits in the heart of Hannibal with rejuvenating hot tub, indoor pool, and hydromassage showers.
￥12,516
￥14,914 total
includes taxes & fees
Nov 15 - Nov 16
Comfort Inn & Suites - Hannibal
A modern reception area with a marble counter, a wooden panel with a light fixture, a fireplace, and a seating area with a sofa and chairs.
A Holiday Inn hotel with a modern facade, a covered entrance, and landscaped areas with shrubs.
An outdoor patio with tables and chairs, green umbrellas, and string lights.
A spacious lobby with a fireplace, seating area, and large windows.

2. Holiday Inn Quincy East by IHG

Holiday Inn Quincy East by IHG
Quincy
  • Revitalizing spa treatments await at this hotel, where an indoor pool, cozy pillow menus, and attentive staff create a relaxing retreat.
￥17,595
￥20,055 total
includes taxes & fees
Nov 8 - Nov 9
Holiday Inn Quincy East by IHG
View all properties

Choose what matters most at spa hotels in Hannibal

Pool
Breakfast included
Hot tub
4 stars
5 stars

Top Hannibal Hotel Reviews

Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West

8/10 Good
"Room was very comfortable, staff was friendly. Breakfast was great. Very clean. Nice area. The restaurant Fiddlesticks is about 300 feet from the hotel."
Timothy 4-night trip
Posted 12 hours ago
Quality Inn & Suites Hannibal West
Best Western On The River

Best Western On The River

10/10 Excellent
"We had a beautiful view of the river. Walking distance to historic downtown. Excellent breakfast!"
Shanda 1-night trip
Posted 2 days ago
Best Western On The River
Baymont by Wyndham Hannibal

Baymont by Wyndham Hannibal

10/10 Excellent
"The staff was great and the rooms were very clean"
Linda 3-night trip
Posted 2 days ago
Baymont by Wyndham Hannibal

Frequently asked questions

Looking to vacation at a spa hotel in Hannibal?
Forget the stress of everyday life and book yourself a hotel with a spa. Travelers recommend the gourmet restaurants in Hannibal. Enjoy the shopping and riverfront during your vacation. Spa hotels are a great way to break out of your routine and add a layer of luxury to your vacation.
What is the best spa hotel in Hannibal?
Comfort Inn & Suites - Hannibal is a top spa hotel featuring a 24-hour fitness center and an indoor pool. Kick back and relax in the hot tub.
How many spa hotels are there in Hannibal?
Among Expedia's 54 accommodation options in Hannibal, there is 1 spa hotel.
What's there to see and do in Hannibal?
Take in the sights and attractions that Hannibal offers with a visit to Rockcliffe Mansion, Mark Twain Boyhood Home and Museum, and Mark Twain Memorial Lighthouse. If you have a little extra time during your trip, you might want to check out Lovers Leap and Mark Twain Cave.
What is a Hannibal spa hotel?
Spa hotels in Hannibal provide lodging and have an on-site spa offering services such as couples massages and beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.

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