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Find hotels near Fort Defiance State Park, Cairo from ￥8,966

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Check prices for these dates

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Sep 7 - Sep 8
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Sep 8 - Sep 9
This weekend
Sep 11 - Sep 13
Next weekend
Sep 18 - Sep 20

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Our top choices for Fort Defiance State Park hotels

A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a painting on the wall.
A compact room with a television on a cabinet, a microwave, a small refrigerator, a table, and a chair.
A bathroom with yellow walls, a wooden cabinet, a sink, a mirror, and a hanging towel rack.
A reception desk with a computer, a framed picture on the wall, and a vase with flowers.

1. La Center Motel

La Center Motel
17.5 km from Fort Defiance State Park
United States
Carrie
￥7,594
￥8,966 total
includes taxes & fees
Sep 20 - Sep 21
La Center Motel
A hotel room with a large bed, two bedside lamps, a framed picture of a bridge, and a wooden nightstand with a phone.
A reception area with a counter, a flat-screen TV, and a window with blinds.
A hotel with a covered entrance, a sign for the brand, and a parking lot with cars.
A reception area with a sofa, a coffee table, a potted plant, and a framed picture on the wall.

2. Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
17.5 km from Fort Defiance State Park
United States
France
￥9,297
￥10,317 total
includes taxes & fees
Sep 8 - Sep 9
Super 8 by Wyndham Charleston/Sikeston East MO
A building with a fountain and flower beds in front.
A hotel room with a beige sofa, two patterned armchairs, a ceiling fan, a flat-screen TV, and a window with curtains.
A reception area with a stone wall, wooden cabinets, and a sign for The Riverstone Hotel.
A modern kitchen with dark wooden cabinets, a central island, and a ceiling fan.

3. The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
20.2 km from Fort Defiance State Park
United States
Bobby
￥10,390
￥11,531 total
includes taxes & fees
Sep 10 - Sep 11
The Riverstone Hotel Charleston-Sikeston
A hotel lobby with a reception desk, seating area, and a large window.
A hotel room with two beds, a desk with a computer, a television, and a window with curtains.
A hotel lobby with a reception desk, two armchairs, a coffee table, and large windows with potted plants.
A hotel room with a desk, chair, television, and a lamp.

4. Quality Inn Cairo I-57

Quality Inn Cairo I-57
7.8 km from Fort Defiance State Park
United States
Susan
￥10,921
￥12,120 total
includes taxes & fees
Oct 2 - Oct 3
Quality Inn Cairo I-57
A hotel room with a large bed, a desk, a television, and a bathroom visible through an open door.
A motel with a sign reading "Eagle Inn" and a parking lot with several cars.
A hotel room with two beds, a nightstand, a lamp, and a window with curtains.
A bathroom with a sink, mirror, towel rack, shower, and toilet.

5. Eagle Inn Charleston

Eagle Inn Charleston
16.2 km from Fort Defiance State Park
United States
Jackson
￥12,030
￥13,350 total
includes taxes & fees
Sep 8 - Sep 9
Eagle Inn Charleston
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Compare popular hotels close to Fort Defiance State Park

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a painting on the wall.
La Center Motel
7.6
Good
22 reviews
View
A hotel room with a large bed, two bedside lamps, a framed picture of a bridge, and a wooden nightstand with a phone.
Super 8 by Wyndham Charleston/Sikeston East MO
6.8
665 reviews
View
A building with a fountain and flower beds in front.
The Riverstone Hotel Charleston-Sikeston
6.8
431 reviews
View
A hotel lobby with a reception desk, seating area, and a large window.
Quality Inn Cairo I-57
6.4
294 reviews
View
A hotel room with a large bed, a desk, a television, and a bathroom visible through an open door.
Eagle Inn Charleston
6.6
107 reviews
View

Top Fort Defiance State Park Hotel Reviews

The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston

10/10 Excellent
"Everything was fine for a one night stay."
Jay 1-night trip
Posted 3 hours ago
The Riverstone Hotel Charleston-Sikeston
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

10/10 Excellent
"Clean and friendly staff. Only stayed the one night so didn’t really get a chance to know the staff. But room was clean and price was decent"
Val 1-night trip
Posted 5 hours ago
Days Inn and Suites by Wyndham Sikeston
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

10/10 Excellent
"This was my second time staying at Drury hotel. I will most definitely book another stay."
Nicole 2-night trip
Posted 11 hours ago
Drury Inn & Suites Sikeston, MO
Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286

Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286

10/10 Excellent
"Super nice host, house is clean and the area is so peaceful. I have so enjoyed my stay here."
Anonymous traveler 10-night trip
Posted 15 hours ago
Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

8/10 Good
"For a older hotel. It was pleasant. Very good staff"
Mark 2-night trip
Posted 3 days ago
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Upscale & Quiet Paducah Retreat on 15 Acres!

Upscale & Quiet Paducah Retreat on 15 Acres!

10/10 Excellent
"Pretty place. Clean. Nicely set back in the woods."
Luanne S. 2-night trip
Posted 3 weeks ago
Upscale & Quiet Paducah Retreat on 15 Acres!
Next door to Wildlife Mgmt Area. Full kitchen, washer/dryer.

Next door to Wildlife Mgmt Area. Full kitchen, washer/dryer.

10/10 Excellent
"Wonderful property!"
Kimberly Y. 1-night trip
Posted 1 month ago
Next door to Wildlife Mgmt Area. Full kitchen, washer/dryer.
Cozy cabin with pond

Cozy cabin with pond

10/10 Excellent
"It was a wonderful experience and a beautiful cabin. The most perfect romantic weekend!"
Meagan R. 2-night trip
Posted 2 months ago
Cozy cabin with pond
Farm stay on 30 acres in Paducah, Kentucky

Farm stay on 30 acres in Paducah, Kentucky

10/10 Excellent
"Great place! A very quiet and peaceful setting, only about 10-12 minutes from town. House is well set up and equipped, was spotless and the host lives nearby and couldn't have been more friendly and helpful. I'd stay here again without hesitation."
John P. 3-night trip
Posted 3 months ago
Farm stay on 30 acres in Paducah, Kentucky

Other attractions near Fort Defiance State Park

Columbus-Belmont State Park

7.4/10 (23 reviews)
You can learn about the history of Columbus with a stop at Columbus-Belmont State Park.
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Ullin City Hall

6.6/10 (4 reviews)
After visiting Ullin City Hall, make a plan to see the other sights and activities in Ullin. Amble around the area's parks or experience its museums.
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Limekin Springs Trail Trailhead

You can take time to visit Limekin Springs Trail Trailhead during your travels to Ullin. Make some time to visit the shops while you're in the area.
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Front Street Studio & Art Gallery

8.6/10 (15 reviews)
You can spend time browsing the exhibits at Front Street Studio & Art Gallery during your travels in Blodgett. While in this relaxing area, you can savor the top-notch restaurants.
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Lower Cache River Access Area

You can take time to visit Lower Cache River Access Area during your travels to Cypress.
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City of Miner Convention Center

Learn about the events happening at City of Miner Convention Center during your trip to Miner. While in this relaxing area, you can savor the top-notch restaurants.
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Henry N Barkhausen Cache River Wetlands Center

8.0/10 (1 review)
You can spend time studying the exhibits at Henry N Barkhausen Cache River Wetlands Center during your travels in Cypress. Amble around the area's parks or experience its museums.
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Frequently asked questions

What's the area like around Fort Defiance State Park?
Fort Defiance State Park is located in Cairo. When you want to settle in and find a place to stay, check out some of the hotels and other accommodations that Expedia offers in the area.
What's the best place to stay close to Fort Defiance State Park?
Quality Inn Cairo I-57 is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and free parking. It's located 4.8 mi (7.8 km) from Fort Defiance State Park. Other good choices around the area include Super 8 by Wyndham Charleston/Sikeston East MO and The Riverstone Hotel Charleston-Sikeston.
If I need to cancel the hotel reservation for my stay near Fort Defiance State Park, will I receive a refund?
Yes! The majority of hotel reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If your reservation is non-refundable, you may still be able to cancel and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then filter by "fully refundable" to review the best options available near Fort Defiance State Park.
Where can I learn more about changing or cancelling my trip in the area near Fort Defiance State Park?
For more information about updating your stay near Fort Defiance State Park or cancelling it, head over to our customer service page.