Florence County Vacations & Trips

Book a Hotel + Flight or Car together to unlock savings

Photo by Deidree DeHart

  • Plan, book, travel with confidence

  • Better together

    Save up to ￥45,448 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

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    Plan, book, and manage your trip all in one place

Top destinations in Florence County

Florence. Italy. Panorama of Florence on a sunny day.
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Florence

Florence

Florence County Hotel Deals

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street Florence SC
Fully refundableReserve now, pay when you stay
The price is ￥10,607 per night from Apr 26 to Apr 27
￥10,607
￥11,880 total
Apr 26 - Apr 27
includes taxes & fees
8.6/10 Excellent! (2,620 reviews)
Excellent value.

Reviewed on Apr 11, 2026

Howard Johnson by Wyndham Florence
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road Florence SC
Fully refundable
The price is ￥14,979 per night from Apr 26 to Apr 27
￥14,979
￥16,777 total
Apr 26 - Apr 27
includes taxes & fees
9/10 Wonderful! (2,255 reviews)
Room was clean, breakfast was hot with a variety. Staff was courteous. Only downfall, pool is permanently closed

Reviewed on Apr 11, 2026

Park Inn by Radisson Florence, SC
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

2.5 out of 5
527 Woody Jones Blvd Florence SC
Fully refundable
The price is ￥17,004 per night from May 11 to May 12
￥17,004
￥19,044 total
May 11 - May 12
includes taxes & fees
9/10 Wonderful! (1,262 reviews)
Safe area, clean hotel. Coffee empty. No water in AM

Reviewed on Apr 11, 2026

Comfort Inn & Suites Florence Center Area
See all 333 properties in Florence County
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Florence County vacation package cost?
Custom build your Florence County package from just . Choose from any combination of rental cars, flights and hotels to build the trip you've been dreaming of. Be sure to add on a few activities!
How do I get a cheap travel package to Florence County?
One of the easiest ways to save money (and time) is to bundle your bookings with Expedia. Hotels, flights, activities and rental cars — we've got everything you need. Pick and choose a combination that best suits you and watch your savings pile up. We know a package deal is never one-size-fits-all. That's why we offer more than 550 airlines and 1,000,000 hotels across the world, which lets you customize your Florence County vacation.
What are the top hotels in Florence County?
Park Inn by Radisson Florence, SC and La Quinta Inn & Suites by Wyndham Florence know how to make their guests feel welcome in Florence. If you also plan to stay in Lake City, check out Days Inn by Wyndham Florence/I-95 North and Country Inn & Suites by Radisson, Florence, SC. Both are popular with travelers.
How far in advance should I book my Florence County vacation?
While not all air carriers advertise ticket prices early, you can usually look up international airfares on Expedia up to a year in advance. This is the time when you'll nab some fantastic deals. If you've left everything to the last minute, there's a chance you could get lucky. Sometimes the cheapest prices become available a few weeks before departure.
What does an Expedia Florence County travel package include?
Choose from a combination of hotels, flights and rental cars. Once you've made your booking, you can add some experiences and tours. Want to pick your airfare class? That's also possible. The choice is yours when it comes to crafting your perfect Florence County escape.
What should I know before booking a Florence County travel package?
You'll save plenty with an Expedia travel package. Bundle your airfares, rental cars and hotels and unlock fantastic discounts. You're not restricted to hotels, though. Book with us and take your pick of beachside villas, creek-side mountain cabins and even treehouses and ranches!
Can I choose my airline with a Florence County Expedia vacation package?
Yes, and with more than 550 airlines to pick from worldwide, you have plenty of choice. Search the available options and find out which airline fits your budget and needs.
If I'm not able to travel, can I cancel my Florence County vacation package?
Yes you can, and we'll help you every step of the way. You may be able to cancel and rebook your Florence County vacation package for free if you booked in the last 24 hours. However, you may incur a fee from your airline, hotel or car rental company for older bookings. If your circumstances unexpectedly change, look up our Customer Service Portal for more information.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.