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Check availability on Esquilino Luxury Hotels

This weekend
Oct 9 - Oct 11
Next weekend
Oct 16 - Oct 18

Our top choices for Esquilino luxury hotels

An outdoor dining area with wicker chairs and a round table, overlooking a historic stone wall and buildings in the background.

1. NH Collection Roma Palazzo Cinquecento

NH Collection Roma Palazzo Cinquecento
5.0 star property
Rome City Centre
9.0 out of 10, Wonderful, (1,001 reviews)
  • cleanliness
    Luxury redefined at this 5-star Rome hotel with rooftop terrace, garden-view dining, and plush rooms steps from Termini Station.
The price is ￥50,684
￥59,293 total
includes taxes & fees
Nov 8 - Nov 9
NH Collection Roma Palazzo Cinquecento
A grand hallway with marble flooring, a red carpet, and a chandelier.

2. BQ HOUSE COLOSSEUM 2Luxury Rooms

BQ HOUSE COLOSSEUM 2Luxury Rooms
Rome City Centre
8.4 out of 10, Very good, (29 reviews)
The price is ￥40,943
￥47,161 total
includes taxes & fees
Nov 3 - Nov 4
BQ HOUSE COLOSSEUM 2Luxury Rooms
A modern bedroom with a large bed, a bedside table with a lamp, a small potted plant, and a view of the outdoors through a window with sheer curtains.

3. Suite Inn Rome

Suite Inn Rome
Rome City Centre
8.6 out of 10, Excellent, (65 reviews)
The price is ￥29,047
￥34,089 total
includes taxes & fees
Nov 6 - Nov 7
Suite Inn Rome
A large, ornate wooden door with a metal grille above it, set within a classical architectural style with detailed moldings and a stone facade.

4. Vacanze Romane Laterano

Vacanze Romane Laterano
Rome Historic Centre
9.8 out of 10, Exceptional, (7 reviews)
The price is ￥47,081
￥59,268 total
includes taxes & fees
Oct 18 - Oct 19
Vacanze Romane Laterano
Terrace/patio

5. Vanella Rome Domus

Vanella Rome Domus
Rome City Centre
8.0 out of 10, Very good, (52 reviews)
The price is ￥32,482
￥37,511 total
includes taxes & fees
Oct 11 - Oct 12
Vanella Rome Domus
A courtyard with a brick structure, lush greenery, and a building with shutters in the background.

6. De Vince Luxury Suites - Roma Termini

De Vince Luxury Suites - Roma Termini
Rome City Centre
7.6 out of 10, Good, (14 reviews)
The price is ￥24,681
￥29,642 total
includes taxes & fees
Nov 2 - Nov 3
De Vince Luxury Suites - Roma Termini
A view through a window with curtains, revealing a street scene with buildings and parked cars.

7. White King Rooms

White King Rooms
Rome Historic Centre
8.8 out of 10, Excellent, (9 reviews)
The price is ￥15,429
￥19,109 total
includes taxes & fees
Nov 2 - Nov 3
White King Rooms
A window with a view of a historic building with a tower and a statue in the foreground.

8. Madonna della Neve

Madonna della Neve
Rome City Centre
8.4 out of 10, Very good, (16 reviews)
The price is ￥20,235
￥24,751 total
includes taxes & fees
Nov 5 - Nov 6
Madonna della Neve
A modern bedroom with a large bed, a desk, and a view of the outdoors through a sliding glass door.

9. Savoia Rooms Roma

Savoia Rooms Roma
Rome Historic Centre
9.4 out of 10, Exceptional, (8 reviews)
The price is ￥15,381
￥19,056 total
includes taxes & fees
Nov 2 - Nov 3
Savoia Rooms Roma
A modern gym with various exercise equipment, a large mirror, and a television.

10. Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World

Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World
5.0 star property
Rome City Centre
9.2 out of 10, Wonderful, (1,005 reviews)
  • cleanliness
    Indulge in ultimate relaxation at this five-star Roman haven featuring a full-service spa, seasonal pool, and elegant dining options.
The price is ￥97,152
￥110,407 total
includes taxes & fees
Nov 3 - Nov 4
Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Esquilino Hotel Reviews

Mecenate Palace

Mecenate Palace

8/10 Good
"Thank you!!"
Lourdes 2-night trip
Posted 4 days ago
Mecenate Palace

Frequently asked questions

Are you searching for the perfect hotel for your luxury getaway to Esquilino?
Arrange a flight into Ciampino Airport (CIA) Airport or Fiumicino - Leonardo da Vinci Intl. Airport (FCO) Airport, and then treat yourself to a stay at one of 17 luxurious hotels. During your visit, you might want to enjoy the sightseeing and museums which Esquilino is known for.
What's the best high-end place to stay in Esquilino?
NH Collection Roma Palazzo Cinquecento is a luxury hotel with a rooftop terrace and a deli, and it's a popular choice for Expedia travelers looking for an elegant place to stay. BQ HOUSE COLOSSEUM 2Luxury Rooms and Le terrazze di San Giovanni are two other upscale options for your vacation.
How many luxury hotels will I find in Esquilino?
Lie in the lap of luxury during your getaway to Esquilino in one of Expedia's 17 luxury hotels.
What's there to see and do in Esquilino?
Enjoy all that Esquilino has to offer when you visit Piazza Vittorio Emanuele II, Piazza Santa Maria Maggiore, and Basilica di Santa Croce in Gerusalemme. If you have a bit of extra time while you're in the area, you might want to check out Via Marsala and Teatro Ambra Jovinelli.
How can I get around Esquilino?
It's easier to get around town comfortably when you know your options. You can access metro transit at S Bibiana Station, Vittorio Emanuele Station, and Manzoni - Museo della Liberazione Station.

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