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Our top choices for Esquilino luxury hotels

An outdoor dining area with wicker chairs and a round table, overlooking a historic stone wall and buildings in the background.

1. NH Collection Roma Palazzo Cinquecento

NH Collection Roma Palazzo Cinquecento
5.0 star property
Rome City Centre
9.0 out of 10, Wonderful, (1,005 reviews)
  • cleanliness
    Luxury redefined at this 5-star Rome hotel with rooftop terrace, garden-view dining, and plush rooms steps from Termini Station.
The price is ￥40,714
￥48,340 total
includes taxes & fees
Nov 8 - Nov 9
NH Collection Roma Palazzo Cinquecento
A grand hallway with marble flooring, a red carpet, and a chandelier.

2. BQ HOUSE COLOSSEUM 2Luxury Rooms

BQ HOUSE COLOSSEUM 2Luxury Rooms
Rome City Centre
8.4 out of 10, Very good, (30 reviews)
The price is ￥59,346
￥67,412 total
includes taxes & fees
Oct 21 - Oct 22
BQ HOUSE COLOSSEUM 2Luxury Rooms
A modern kitchen with white cabinets, a built-in washing machine, a black sink, and a marble countertop.

3. Rhome Sweet Rhome Apt

Rhome Sweet Rhome Apt
Rome City Centre
8.0 out of 10, Very good, (6 reviews)
The price is ￥37,970
￥64,722 total
includes taxes & fees
Nov 9 - Nov 10
Rhome Sweet Rhome Apt
Terrace/patio

4. Vanella Rome Domus

Vanella Rome Domus
Rome City Centre
8.0 out of 10, Very good, (56 reviews)
The price is ￥29,635
￥34,375 total
includes taxes & fees
Nov 20 - Nov 21
Vanella Rome Domus
A courtyard with a brick structure, lush greenery, and a building with shutters in the background.

5. De Vince Luxury Suites - Roma Termini

De Vince Luxury Suites - Roma Termini
Rome City Centre
7.6 out of 10, Good, (14 reviews)
The price is ￥22,402
￥27,130 total
includes taxes & fees
Nov 20 - Nov 21
De Vince Luxury Suites - Roma Termini
A modern bedroom with a large bed, a bedside table with a lamp, a small potted plant, and a view of the outdoors through a window with sheer curtains.

6. Suite Inn Rome

Suite Inn Rome
Rome City Centre
8.6 out of 10, Excellent, (66 reviews)
The price is ￥22,350
￥26,718 total
includes taxes & fees
Nov 17 - Nov 18
Suite Inn Rome
A table with a tray containing a mug, a book, a glass of orange juice, and a small container of snacks.

7. Rhome GuestHouse

Rhome GuestHouse
Rome City Centre
9.4 out of 10, Exceptional, (42 reviews)
The price is ￥28,548
￥33,891 total
includes taxes & fees
Nov 11 - Nov 12
Rhome GuestHouse
A large, ornate wooden door with a metal grille above it, set within a classical architectural style with detailed moldings and a stone facade.

8. Vacanze Romane Laterano

Vacanze Romane Laterano
Rome Historic Centre
9.6 out of 10, Exceptional, (9 reviews)
The price is ￥25,752
￥35,791 total
includes taxes & fees
Nov 12 - Nov 13
Vacanze Romane Laterano
A modern hotel room with a large bed, a bedside table, a mirror, and a bench.

9. Domus Domas & Boutique

Domus Domas & Boutique
Rome City Centre
7.0 out of 10, Good, (50 reviews)
The price is ￥21,165
￥25,414 total
includes taxes & fees
Nov 3 - Nov 4
Domus Domas & Boutique
A view through a window with curtains, revealing a street scene with buildings and parked cars.

10. White King Rooms

White King Rooms
Rome Historic Centre
8.8 out of 10, Excellent, (10 reviews)
The price is ￥14,731
￥18,337 total
includes taxes & fees
Nov 15 - Nov 16
White King Rooms
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Esquilino Hotel Reviews

Champagne Palace Hotel

Champagne Palace Hotel

10/10 Excellent
"It’s in the perfect location, two minute walk to the main train terminal and it was only a 40 minute walk to the coliseum. It was a busy neighborhood with lots of restaurants nearby. The room itself was very nice but I had some noisy neighbours which made it hard to sleep. Otherwise it was a good stay."
Shannon 3-night trip
Posted 4 hours ago
Champagne Palace Hotel

Frequently asked questions

Are you searching for the perfect hotel for your luxury getaway to Esquilino?
Arrange a flight into Ciampino Airport (CIA) Airport or Fiumicino - Leonardo da Vinci Intl. Airport (FCO) Airport, and then treat yourself to a stay at one of 17 luxurious hotels. During your visit, you might want to enjoy the sightseeing and museums which Esquilino is known for.
What's the best high-end place to stay in Esquilino?
NH Collection Roma Palazzo Cinquecento is a luxury hotel with a rooftop terrace and a deli, and it's a popular choice for Expedia travelers looking for an elegant place to stay. BQ HOUSE COLOSSEUM 2Luxury Rooms and Le terrazze di San Giovanni are two other upscale options for your vacation.
How many luxury hotels will I find in Esquilino?
Lie in the lap of luxury during your getaway to Esquilino in one of Expedia's 17 luxury hotels.
What's there to see and do in Esquilino?
Enjoy all that Esquilino has to offer when you visit Piazza Vittorio Emanuele II, Piazza Santa Maria Maggiore, and Basilica di Santa Croce in Gerusalemme. If you have a bit of extra time while you're in the area, you might want to check out Via Marsala and Teatro Ambra Jovinelli.
How can I get around Esquilino?
It's easier to get around town comfortably when you know your options. You can access metro transit at S Bibiana Station, Vittorio Emanuele Station, and Manzoni - Museo della Liberazione Station.

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