Two men sitting on a bench in a park, reading newspapers.

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Check availability on Esquilino Luxury Hotels

This weekend
Oct 30 - Nov 1
Next weekend
Nov 6 - Nov 8

Our top choices for Esquilino luxury hotels

An outdoor dining area with wicker chairs and a round table, overlooking a historic stone wall and buildings in the background.

1. NH Collection Roma Palazzo Cinquecento

NH Collection Roma Palazzo Cinquecento
5.0 star property
Rome City Centre
9.0 out of 10, Wonderful, (1,001 reviews)
  • cleanliness
    Luxury redefined at this 5-star Rome hotel with rooftop terrace, garden-view dining, and plush rooms steps from Termini Station.
The price is ￥46,008
￥54,124 total
includes taxes & fees
Nov 8 - Nov 9
NH Collection Roma Palazzo Cinquecento
A grand hallway with marble flooring, a red carpet, and a chandelier.

2. BQ HOUSE COLOSSEUM 2Luxury Rooms

BQ HOUSE COLOSSEUM 2Luxury Rooms
Rome City Centre
8.4 out of 10, Very good, (31 reviews)
The price is ￥58,723
￥66,704 total
includes taxes & fees
Oct 27 - Oct 28
BQ HOUSE COLOSSEUM 2Luxury Rooms
A modern kitchen with white cabinets, a built-in washing machine, a black sink, and a marble countertop.

3. Rhome Sweet Rhome Apt

Rhome Sweet Rhome Apt
Rome City Centre
8.0 out of 10, Very good, (6 reviews)
The price is ￥37,544
￥63,995 total
includes taxes & fees
Nov 9 - Nov 10
Rhome Sweet Rhome Apt
A modern bedroom with a large bed, a bedside table with a lamp, a small potted plant, and a view of the outdoors through a window with sheer curtains.

4. Suite Inn Rome

Suite Inn Rome
Rome City Centre
8.6 out of 10, Excellent, (66 reviews)
The price is ￥23,603
￥28,072 total
includes taxes & fees
Nov 18 - Nov 19
Suite Inn Rome
Terrace/patio

5. Vanella Rome Domus

Vanella Rome Domus
Rome City Centre
8.0 out of 10, Very good, (57 reviews)
The price is ￥29,633
￥34,354 total
includes taxes & fees
Nov 25 - Nov 26
Vanella Rome Domus
A table with a tray containing a mug, a book, a glass of orange juice, and a small container of snacks.

6. Rhome GuestHouse

Rhome GuestHouse
Rome City Centre
9.4 out of 10, Exceptional, (42 reviews)
The price is ￥28,227
￥33,510 total
includes taxes & fees
Nov 25 - Nov 26
Rhome GuestHouse
A courtyard with a brick structure, lush greenery, and a building with shutters in the background.

7. De Vince Luxury Suites - Roma Termini

De Vince Luxury Suites - Roma Termini
Rome City Centre
7.6 out of 10, Good, (14 reviews)
The price is ￥21,509
￥26,120 total
includes taxes & fees
Nov 23 - Nov 24
De Vince Luxury Suites - Roma Termini
A modern hotel room with a large bed, a bedside table, a mirror, and a bench.

8. Domus Domas & Boutique

Domus Domas & Boutique
Rome City Centre
7.0 out of 10, Good, (50 reviews)
The price is ￥20,927
￥25,129 total
includes taxes & fees
Nov 3 - Nov 4
Domus Domas & Boutique
A large, ornate wooden door with a metal grille above it, set within a classical architectural style with detailed moldings and a stone facade.

9. Vacanze Romane Laterano

Vacanze Romane Laterano
Rome Historic Centre
9.6 out of 10, Exceptional, (9 reviews)
The price is ￥23,974
￥33,752 total
includes taxes & fees
Nov 12 - Nov 13
Vacanze Romane Laterano
A view through a window with curtains, revealing a street scene with buildings and parked cars.

10. White King Rooms

White King Rooms
Rome Historic Centre
8.8 out of 10, Excellent, (10 reviews)
The price is ￥14,799
￥18,387 total
includes taxes & fees
Nov 5 - Nov 6
White King Rooms
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Esquilino Hotel Reviews

Mecenate Palace

Mecenate Palace

10/10 Excellent
"Great location and small but comfortable room. Be warned - the beautiful top floor balcony is a hookah bar. We went up to enjoy the sunset and have a drink at one of the limited number of tables. Unfortunately, the person at the table next to us was an obnoxious, self-obsessed individual talking loudly on face-time while sucking loudly and continuously on a gurgling three foot hookah suppled by the hotel. In addition to the noise, we were subject to great wafts of sweet smelling smoke."
marc 3-night trip
Posted 3 days ago
Mecenate Palace

Frequently asked questions

Are you searching for the perfect hotel for your luxury getaway to Esquilino?
Arrange a flight into Ciampino Airport (CIA) Airport or Fiumicino - Leonardo da Vinci Intl. Airport (FCO) Airport, and then treat yourself to a stay at one of 17 luxurious hotels. During your visit, you might want to enjoy the sightseeing and museums which Esquilino is known for.
What's the best high-end place to stay in Esquilino?
NH Collection Roma Palazzo Cinquecento is a luxury hotel with a rooftop terrace and a deli, and it's a popular choice for Expedia travelers looking for an elegant place to stay. BQ HOUSE COLOSSEUM 2Luxury Rooms and Le terrazze di San Giovanni are two other upscale options for your vacation.
How many luxury hotels will I find in Esquilino?
Lie in the lap of luxury during your getaway to Esquilino in one of Expedia's 17 luxury hotels.
What's there to see and do in Esquilino?
Enjoy all that Esquilino has to offer when you visit Piazza Vittorio Emanuele II, Piazza Santa Maria Maggiore, and Basilica di Santa Croce in Gerusalemme. If you have a bit of extra time while you're in the area, you might want to check out Via Marsala and Teatro Ambra Jovinelli.
How can I get around Esquilino?
It's easier to get around town comfortably when you know your options. You can access metro transit at S Bibiana Station, Vittorio Emanuele Station, and Manzoni - Museo della Liberazione Station.

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