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Our top choices for Esquilino luxury hotels

An outdoor dining area with wicker chairs and a round table, overlooking a historic stone wall and buildings in the background.

1. NH Collection Roma Palazzo Cinquecento

NH Collection Roma Palazzo Cinquecento
5.0 star property
Rome City Centre
9.0 out of 10, Wonderful, (1,002 reviews)
  • cleanliness
    Luxury redefined at this 5-star Rome hotel with rooftop terrace, garden-view dining, and plush rooms steps from Termini Station.
The price is ￥33,129
￥39,963 total
includes taxes & fees
Dec 8 - Dec 9
NH Collection Roma Palazzo Cinquecento
A modern bedroom with a large bed, a bedside table with a lamp, a small potted plant, and a view of the outdoors through a window with sheer curtains.

2. Suite Inn Rome

Suite Inn Rome
Rome City Centre
8.6 out of 10, Excellent, (66 reviews)
The price is ￥23,648
￥28,126 total
includes taxes & fees
Nov 22 - Nov 23
Suite Inn Rome
Terrace/patio

3. Vanella Rome Domus

Vanella Rome Domus
Rome City Centre
8.0 out of 10, Very good, (59 reviews)
The price is ￥20,890
￥24,739 total
includes taxes & fees
Nov 15 - Nov 16
Vanella Rome Domus
A bottle of wine and two glasses on a wicker table with a bouquet of flowers.

4. Le terrazze di San Giovanni

Le terrazze di San Giovanni
Rome Historic Centre
8.4 out of 10, Very good, (433 reviews)
The price is ￥10,585
￥20,446 total
includes taxes & fees
Nov 16 - Nov 17
Le terrazze di San Giovanni
A grand hallway with marble flooring, a red carpet, and a chandelier.

5. BQ HOUSE COLOSSEUM 2Luxury Rooms

BQ HOUSE COLOSSEUM 2Luxury Rooms
Rome City Centre
8.4 out of 10, Very good, (32 reviews)
The price is ￥43,937
￥50,444 total
includes taxes & fees
Nov 15 - Nov 16
BQ HOUSE COLOSSEUM 2Luxury Rooms
A modern kitchen with white cabinets, a built-in washing machine, a black sink, and a marble countertop.

6. Rhome Sweet Rhome Apt

Rhome Sweet Rhome Apt
Rome City Centre
8.0 out of 10, Very good, (6 reviews)
The price is ￥37,236
￥63,699 total
includes taxes & fees
Dec 10 - Dec 11
Rhome Sweet Rhome Apt
A table with a tray containing a mug, a book, a glass of orange juice, and a small container of snacks.

7. Rhome GuestHouse

Rhome GuestHouse
Rome City Centre
9.4 out of 10, Exceptional, (42 reviews)
The price is ￥27,368
￥32,570 total
includes taxes & fees
Nov 15 - Nov 16
Rhome GuestHouse
A bedroom with a bed, bedside tables, a small table with a bowl, a plant, and a fruit bowl.

8. Domus Domas & Boutique

Domus Domas & Boutique
Rome City Centre
7.0 out of 10, Good, (50 reviews)
The price is ￥17,058
￥20,877 total
includes taxes & fees
Dec 3 - Dec 4
Domus Domas & Boutique
A modern hallway with a marble floor, recessed lighting, and a shelf with decorative items.

9. Savoia Rooms Roma

Savoia Rooms Roma
Rome Historic Centre
9.2 out of 10, Wonderful, (10 reviews)
The price is ￥10,457
￥13,616 total
includes taxes & fees
Nov 24 - Nov 25
Savoia Rooms Roma
A street view with yellow and pink buildings, parked cars, and a clear sky.

10. White King Rooms

White King Rooms
Rome Historic Centre
8.8 out of 10, Excellent, (10 reviews)
The price is ￥15,242
￥18,886 total
includes taxes & fees
Nov 29 - Nov 30
White King Rooms
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Esquilino Hotel Reviews

Hotel Emona Aquaeductus

Hotel Emona Aquaeductus

10/10 Excellent
"Best place we stayed in from Switzerland through out Italy"
Tim 2-night trip
Posted 7 days ago
Hotel Emona Aquaeductus
Champagne Palace Hotel

Champagne Palace Hotel

10/10 Excellent
"The front desk people specially afternoon guys were very helpful and i am very thankful that they were there and helped me for any problem that I had. 🙏"
thelma 8-night trip
Posted 2 weeks ago
Champagne Palace Hotel

Frequently asked questions

Are you searching for the perfect hotel for your luxury getaway to Esquilino?
Arrange a flight into Ciampino Airport (CIA) Airport or Fiumicino - Leonardo da Vinci Intl. Airport (FCO) Airport, and then treat yourself to a stay at one of 17 luxurious hotels. During your visit, you might want to enjoy the sightseeing and museums which Esquilino is known for.
What's the best high-end place to stay in Esquilino?
NH Collection Roma Palazzo Cinquecento is a luxury hotel with a rooftop terrace and a deli, and it's a popular choice for Expedia travelers looking for an elegant place to stay. BQ HOUSE COLOSSEUM 2Luxury Rooms and Le terrazze di San Giovanni are two other upscale options for your vacation.
How many luxury hotels will I find in Esquilino?
Lie in the lap of luxury during your getaway to Esquilino in one of Expedia's 17 luxury hotels.
What's there to see and do in Esquilino?
Enjoy all that Esquilino has to offer when you visit Piazza Vittorio Emanuele II, Piazza Santa Maria Maggiore, and Basilica di Santa Croce in Gerusalemme. If you have a bit of extra time while you're in the area, you might want to check out Via Marsala and Teatro Ambra Jovinelli.
How can I get around Esquilino?
It's easier to get around town comfortably when you know your options. You can access metro transit at S Bibiana Station, Vittorio Emanuele Station, and Manzoni - Museo della Liberazione Station.

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