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Check availability on Esquilino Luxury Hotels

Next weekend
Oct 2 - Oct 4
In two weeks
Oct 9 - Oct 11

Our top choices for Esquilino luxury hotels

An outdoor dining area with wicker chairs and a round table, overlooking a historic stone wall and buildings in the background.

1. NH Collection Roma Palazzo Cinquecento

NH Collection Roma Palazzo Cinquecento
5.0 star property
Rome City Centre
9.0 out of 10, Wonderful, (1,001 reviews)
  • cleanliness
    Luxury redefined at this 5-star Rome hotel with rooftop terrace, garden-view dining, and plush rooms steps from Termini Station.
The price is ￥88,506
￥100,968 total
includes taxes & fees
Oct 15 - Oct 16
NH Collection Roma Palazzo Cinquecento
A rooftop terrace with dining tables and chairs, a view of a historic building, and a decorative garland.

2. Doria Palace Boutique Hotel

Doria Palace Boutique Hotel
4.0 star property
Rome City Centre
8.8 out of 10, Excellent, (90 reviews)
The price is ￥47,586
￥55,053 total
includes taxes & fees
Oct 26 - Oct 27
Doria Palace Boutique Hotel

3. Hilton Garden Inn Rome Colosseum

Hilton Garden Inn Rome Colosseum
4.0 star property
Rome Historic Centre
8.6 out of 10, Excellent, (1,001 reviews)
The price is ￥40,476
￥47,233 total
includes taxes & fees
Oct 25 - Oct 26
Hilton Garden Inn Rome Colosseum
A multi-story building with a classical architectural style, featuring a covered entrance with a canopy, large potted plants, and a sign indicating a hotel.

4. Mecenate Palace

Mecenate Palace
4.0 star property
Rome City Centre
9.0 out of 10, Wonderful, (1,002 reviews)
The price is ￥40,390
￥47,139 total
includes taxes & fees
Oct 26 - Oct 27
Mecenate Palace
A buffet with various food items and a view of the sea.

5. Mercure Roma Centro St. John

Mercure Roma Centro St. John
4.0 star property
Rome Historic Centre
7.8 out of 10, Good, (233 reviews)
The price is ￥38,424
￥44,975 total
includes taxes & fees
Oct 18 - Oct 19
Mercure Roma Centro St. John
A modern kitchen with a central island, a large window with a view of the street, and a person working at the counter.

6. Hotel Aphrodite

Hotel Aphrodite
4.0 star property
Rome City Centre
7.8 out of 10, Good, (1,001 reviews)
The price is ￥26,920
￥32,321 total
includes taxes & fees
Sep 27 - Sep 28
Hotel Aphrodite
The entrance to Hotel Napoleon with a large wooden door, a glass window above, and a sign with the hotel's name. There are two potted plants on either side of the door.

7. Napoleon Hotel

Napoleon Hotel
4.0 star property
Rome City Centre
8.6 out of 10, Excellent, (1,041 reviews)
The price is ￥29,655
￥35,329 total
includes taxes & fees
Sep 27 - Sep 28
Napoleon Hotel
A modern interior with a geometric metal wall art piece and a vertical photo display.

8. Hotel Ariston

Hotel Ariston
4.0 star property
Rome City Centre
8.0 out of 10, Very good, (750 reviews)
The price is ￥31,941
￥37,844 total
includes taxes & fees
Oct 25 - Oct 26
Hotel Ariston
A terrace with a table, chairs, and a view of historic buildings at sunset.

9. Hotel Palladium Palace

Hotel Palladium Palace
4.0 star property
Rome City Centre
8.2 out of 10, Very good, (1,002 reviews)
The price is ￥33,237
￥39,247 total
includes taxes & fees
Oct 25 - Oct 26
Hotel Palladium Palace
The exterior of Hotel Morgana with a classic facade, large windows, and a welcoming entrance.

10. Hotel Morgana

Hotel Morgana
4.0 star property
Rome City Centre
8.2 out of 10, Very good, (1,000 reviews)
The price is ￥32,808
￥38,798 total
includes taxes & fees
Oct 25 - Oct 26
Hotel Morgana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Esquilino Hotel Reviews

Mecenate Palace

Mecenate Palace

10/10 Excellent
"We enjoyed our stay! The room was small, but very adequate. The location was wonderful. The breakfast buffet was excellent with plenty of choices of hearty or sweet foods. We would definitely stay again on another visit to Rome!"
Sharon 2-night trip
Posted 4 days ago
Mecenate Palace

Frequently asked questions

Are you searching for the perfect hotel for your luxury getaway to Esquilino?
Arrange a flight into Ciampino Airport (CIA) Airport or Fiumicino - Leonardo da Vinci Intl. Airport (FCO) Airport, and then treat yourself to a stay at one of 17 luxurious hotels. During your visit, you might want to enjoy the sightseeing and museums which Esquilino is known for.
What's the best high-end place to stay in Esquilino?
NH Collection Roma Palazzo Cinquecento is a luxury hotel with a rooftop terrace and a deli, and it's a popular choice for Expedia travelers looking for an elegant place to stay. BQ HOUSE COLOSSEUM 2Luxury Rooms and Le terrazze di San Giovanni are two other upscale options for your vacation.
How many luxury hotels will I find in Esquilino?
Lie in the lap of luxury during your getaway to Esquilino in one of Expedia's 17 luxury hotels.
What's there to see and do in Esquilino?
Enjoy all that Esquilino has to offer when you visit Piazza Vittorio Emanuele II, Piazza Santa Maria Maggiore, and Basilica di Santa Croce in Gerusalemme. If you have a bit of extra time while you're in the area, you might want to check out Via Marsala and Teatro Ambra Jovinelli.
How can I get around Esquilino?
It's easier to get around town comfortably when you know your options. You can access metro transit at S Bibiana Station, Vittorio Emanuele Station, and Manzoni - Museo della Liberazione Station.