Eastern South Dakota Vacations

Book a Hotel + Flight or Car together to unlock savings

Photo by De Smet Development Corporation

  • Plan, book, travel with confidence

  • Better together

    Save up to ￥45,448 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in Eastern South Dakota

Find the best Eastern South Dakota areas and neighborhoods for the activities you enjoy most. Learn more about Eastern South Dakota
Default Image

Downtown Sioux Falls

1 out of top 10 points of interest in this area
4.5/5(108 area reviews)

While visiting Downtown Sioux Falls, you might make a stop by sights like Washington Pavilion of Arts and Science and Michelangelo's David.

Find hotels in Downtown Sioux Falls

Find the Best Eastern South Dakota Vacation Packages

Eastern South Dakota Hotel Deals

Days Inn by Wyndham Sioux Falls Empire

Days Inn by Wyndham Sioux Falls Empire

2 out of 5
3401 Gateway Blvd, I-29 and 41st Street Exit 77, Sioux Falls, SD
Fully refundableReserve now, pay when you stay
The price is ￥9,090 per night from Nov 20 to Nov 21
￥9,090
￥10,280 total
Nov 20 - Nov 21
includes taxes & fees
7.8/10 Good! (1,035 reviews)
Clean, good breakfast. Bad...heater/ac motor kept going off and on and it was very loud, so I didn't sleep real well.

Reviewed on Nov 5, 2025

Days Inn by Wyndham Sioux Falls Empire
Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr

Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr

3 out of 5
1301 West Russell, I-29 and Exit 81, Sioux Falls, SD
Fully refundableReserve now, pay when you stay
The price is ￥9,220 per night from Nov 16 to Nov 17
￥9,220
￥10,421 total
Nov 16 - Nov 17
includes taxes & fees
7.6/10 Good! (1,427 reviews)
They were very nice

Reviewed on Nov 8, 2025

Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr
Holiday Inn Sioux Falls-City Centre by IHG

Holiday Inn Sioux Falls-City Centre by IHG

3 out of 5
100 W 8th St, Sioux Falls, SD
Fully refundable
The price is ￥15,868 per night from Nov 24 to Nov 25
￥15,868
￥20,721 total
Nov 24 - Nov 25
includes taxes & fees
8.4/10 Very Good! (1,003 reviews)
The room was very clean and nice

Reviewed on Nov 11, 2025

Holiday Inn Sioux Falls-City Centre by IHG
See all 878 properties in Eastern South Dakota
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Eastern South Dakota

Sioux Falls featuring a park and a waterfall

Falls Park

4.5/5(467 reviews)

Falls Park is just one of the places to see in Sioux Falls, so why not enjoy the other things to explore during your travels? Attend a sporting event or discover the area's beautiful waterfalls.

Falls Park
Corn Palace

Corn Palace

4/5(163 reviews)

After visiting Corn Palace, make a plan to see the other sights and activities in Mitchell. While in this family-friendly area, you can savor the top-notch restaurants.

Corn Palace

Augustana College

4/5(78 reviews)

Take a campus tour or just explore the area of Augustana College, during your trip to Sioux Falls. Attend a sporting event or discover the area's beautiful waterfalls.

Augustana College

Frequently asked questions

Can I cancel my flight booking to Eastern South Dakota due to COVID-19?
Check out our Customer Service Portal for important details about changing or canceling flights due to COVID-19. Make sure you also check the terms and conditions of your preferred airline before booking your fare to Eastern South Dakota.
What's the best way to find cheap flights to Eastern South Dakota that have flexible change policies?
At Expedia, we've been channeling our inner Olympic gymnast to provide you with the most flexible fares on the market. Simply tick the "No change fee" box right under the "Flexible change policies" subheading to find your dream flight to Eastern South Dakota.
What are some of the general tips for travelers to Eastern South Dakota during the COVID-19 outbreak?
With new safety guidelines to follow, travel looks a little different right now. Here are a few things to know before you jet off to Eastern South Dakota:
  • Before you lock in a flight, find out if any travel restrictions apply — in both your destination and origin. Get the latest updates by checking government and travel websites.
  • Requirements state you must wear a face mask throughout your travel experience, including at security checkpoints. You should be prepared to adjust your mask for ID purposes when asked by a TSA employee.
  • Do not hand your boarding pass (electronic or paper) directly to a TSA officer. Rather, you should place the pass on the scanner and then hold it up for inspection.
  • You're permitted to take one container of hand sanitizer up to 12 oz (350 ml) in your carry-on bag. You'll have to remove it for screening.
  • To minimize handling during screening, place items such as your wallet, phone and belt into your carry-on instead of the bins.
  • If you want to take food through security screening, put it in a clear plastic bag and then into a screening bin. This reduces the likelihood that a TSA agent will need to touch your food container or carry-on bag for inspection.

Which airlines fly to Eastern South Dakota?
Delta is a renowned air carrier servicing Eastern South Dakota. Look up airfares to Sioux Falls Regional Airport (FSD) and you'll have 182 Delta flights per month to select from.
How can I find cheap tickets to Eastern South Dakota?
To pick up an awesome deal to Eastern South Dakota, book ahead of time. Also think about using Expedia's "flexible dates" link above your search results. This will display prices for the days around your travel dates. In the last seven days, was the lowest price for a flight to Eastern South Dakota.
How much is a flight to Eastern South Dakota?
If you were jetting one way from (), you could've picked up a cheap fare for in the last seven days. Return flights to Eastern South Dakota ranged from only to during this same period.
What are the most popular airports to fly into in Eastern South Dakota?
Book your flight to Sioux Falls Regional Airport (FSD) and sample everything that Eastern South Dakota has to offer. As the region's main point of entry, roughly 803 flights touch down here every month.
When is the cheapest time to fly to Eastern South Dakota?
Fly out on a Tuesday to increase your chances of scoring the cheapest fare to Eastern South Dakota. Mondays are usually the next most affordable day to depart. Saturday is generally the priciest day to fly anywhere.
How much is a plane ticket to Eastern South Dakota?
In the last seven days, seats ranged between and . Check out our amazing deals to Eastern South Dakota, pick your favorite and get ready for your next fun vacation!
Which airlines with flights to Eastern South Dakota employ COVID-19 cleanliness policies?
To minimize contact between travelers and cabin crew during the ongoing pandemic, airlines have taken social distancing and other measures to the skies. A good example of these are:
  • American Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.
  • United Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.
  • Delta - this airline is known for electrostatic cleaning and cleaning with disinfectant.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.