East Cape Girardeau Vacation Rentals

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Check prices for these dates

In two weeks
Dec 26 - Dec 28
In two months
Feb 6 - Feb 8
In three months
Mar 6 - Mar 8
In four months
Apr 3 - Apr 5

Our top choices for East Cape Girardeau vacation rentals

Outdoor spa tub
Cabin in Southern Illinois - Hot Tub - Romantic Getaway -Shawnee National Forest

Cabin in Southern Illinois - Hot Tub - Romantic Getaway -Shawnee National Forest

Cabin in Southern Illinois - Hot Tub - Romantic Getaway -Shawnee National Forest
Jonesboro
10.0 out of 10, Exceptional, (268)
"Had an amazing stay!"
United States
Shauna W.
Cabin in Southern Illinois - Hot Tub - Romantic Getaway -Shawnee National Forest
Interior
The Twisted Sassafras Treehouse

The Twisted Sassafras Treehouse

The Twisted Sassafras Treehouse
Cape Girardeau
10.0 out of 10, Exceptional, (27)
"The place was awesome very clean the host was very accommodating. Nice a quiet for a relaxing stay highly recommend "
United States
Gary C.
The price is ￥32,046
￥46,875 total
includes taxes & fees
Dec 15 - Dec 16
The Twisted Sassafras Treehouse
Interior
Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO

Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO

Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO
Cape Girardeau
9.4 out of 10, Exceptional, (45)
"This place is AWESOME! It's clean, artsy, fun, and if we ever have a chance, we will certainly return!"
United States
Jordan S.
The price is ￥12,735
￥21,511 total
includes taxes & fees
Dec 14 - Dec 15
Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO
Exterior
“Brickyard”-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau

“Brickyard”-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau

“Brickyard”-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau
Cape Girardeau
10.0 out of 10, Exceptional, (28)
"Great property and a super host! He was super helpful and always willing to help with any questions we had. Would definitely rent here again!"
United States
Mark M.
“Brickyard”-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau
Dining
Cozy cabins on beautiful Horseshoe Lake

Cozy cabins on beautiful Horseshoe Lake

Cozy cabins on beautiful Horseshoe Lake
Olive Branch
9.8 out of 10, Exceptional, (35)
"Beautiful place, host was kind and and quick to respond to messages "
United States
Melissa W.
The price is ￥17,529
￥21,881 total
includes taxes & fees
Dec 26 - Dec 27
Cozy cabins on beautiful Horseshoe Lake
Living area
Little Blue Cottage on Spanish

Little Blue Cottage on Spanish

Little Blue Cottage on Spanish
Cape Girardeau
8.6 out of 10, Excellent, (48)
"I would definitely stay here again!"
United States
Bonita
The price is ￥12,595
￥15,705 total
includes taxes & fees
Dec 14 - Dec 15
Little Blue Cottage on Spanish
Microwave, oven, stovetop, dishwasher
Greenway Getaway~Charming 3-bedroom, 3 BA home in the heart of Jackson, Missouri

Greenway Getaway~Charming 3-bedroom, 3 BA home in the heart of Jackson, Missouri

Greenway Getaway~Charming 3-bedroom, 3 BA home in the heart of Jackson, Missouri
Jackson
Greenway Getaway~Charming 3-bedroom, 3 BA home in the heart of Jackson, Missouri
Smart TV
Peaceful secluded cabin located near Horseshoe Lake

Peaceful secluded cabin located near Horseshoe Lake

Peaceful secluded cabin located near Horseshoe Lake
Miller City
9.8 out of 10, Exceptional, (20)
"cute A frame in a secluded spot. Couldn’t ask for a more relaxing situation. "
United States
Jason M.
Peaceful secluded cabin located near Horseshoe Lake
Exterior
Magical Victorian near hiking / wine trail

Magical Victorian near hiking / wine trail

Magical Victorian near hiking / wine trail
Anna
10.0 out of 10, Exceptional, (4)
"The house was beautiful! We were in awe of the decor and layout. This is a must-stay if you are in southern Illinois!"
United States
Lori C.
The price is ￥32,326
￥61,169 total
includes taxes & fees
Dec 17 - Dec 18
Magical Victorian near hiking / wine trail
Interior
3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau

3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau

3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau
2.0 star property
Cape Girardeau
10.0 out of 10, Exceptional, (3)
"Cute place, clean and spacious. Convenient location. Very nice stay! Would stay again. "
United States
Rebecca E.
3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau
Exterior
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
Cape Girardeau
8.6 out of 10, Excellent, (36)
"Very nice house. The pool and hot tub were perfect for a short getaway. Tons of activities and games to keep the fanily entertained. Will definitely come back! "
United States
Emily D.
The price is ￥20,991
￥33,237 total
includes taxes & fees
Dec 15 - Dec 16
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
Interior
Historic Victorian - Walkable to Downtown Cape Girardeau - King Bed - Fast Wifi

Historic Victorian - Walkable to Downtown Cape Girardeau - King Bed - Fast Wifi

Historic Victorian - Walkable to Downtown Cape Girardeau - King Bed - Fast Wifi
Cape Girardeau
10.0 out of 10, Exceptional, (10)
"A large and comfortable house with cool historical details and just about everything you need to have a great, easy, smooth-running vacation. Great location for downtown exploring."
United States
Virginia C.
Historic Victorian - Walkable to Downtown Cape Girardeau - King Bed - Fast Wifi
Exterior
The Rested Duck Mallard Room

The Rested Duck Mallard Room

The Rested Duck Mallard Room
Olive Branch
9.2 out of 10, Wonderful, (25)
"This is an excellent place to stay. With a nice lake right across the street. If i. In the are i will stay again for sure"
United States
mike b.
The price is ￥17,529
￥21,881 total
includes taxes & fees
Dec 26 - Dec 27
The Rested Duck Mallard Room
Fridge, microwave, oven, stovetop
Historical 'Kage House' Short Term Rental located in "Old Town Cape"

Historical 'Kage House' Short Term Rental located in "Old Town Cape"

Historical 'Kage House' Short Term Rental located in "Old Town Cape"
Cape Girardeau
10.0 out of 10, Exceptional, (223)
"Property location was perfect.Deck view was great.Very clean and comfortable place."
United States
Robert M.
Historical 'Kage House' Short Term Rental located in "Old Town Cape"
Fridge, microwave, oven, stovetop
Relax in the country at Countryside Villas! - Villa A

Relax in the country at Countryside Villas! - Villa A

Relax in the country at Countryside Villas! - Villa A
Jackson
10.0 out of 10, Exceptional, (33)
"Great place to stay, felt like home away from home. "
United States
Brittany
The price is ￥23,324
￥28,727 total
includes taxes & fees
Dec 17 - Dec 18
Relax in the country at Countryside Villas! - Villa A
Fridge, microwave, oven, stovetop
River's Dawn - Modernized Historic Home - River Views - King Bed - Fast Wifi

River's Dawn - Modernized Historic Home - River Views - King Bed - Fast Wifi

River's Dawn - Modernized Historic Home - River Views - King Bed - Fast Wifi
Cape Girardeau
10.0 out of 10, Exceptional, (4)
"The home was beautiful inside and very clean. The bed was comfortable, and the area was quiet. My father and I really enjoyed our stay. I would stay there again over anywhere else I have stayed in cape. "
United States
Shawn
River's Dawn - Modernized Historic Home - River Views - King Bed - Fast Wifi
Smart TV, fireplace
Quaint, Beautiful Home next to SEMO and Hospital

Quaint, Beautiful Home next to SEMO and Hospital

Quaint, Beautiful Home next to SEMO and Hospital
Cape Girardeau
9.8 out of 10, Exceptional, (43)
"Location was perfect. The house was clean and met all our needs. Would definitely stay here again in the future."
United States
Beau L.
Quaint, Beautiful Home next to SEMO and Hospital
Interior
Charming 2-bedroom with AC, WiFi in lovely Jonesboro

Charming 2-bedroom with AC, WiFi in lovely Jonesboro

Charming 2-bedroom with AC, WiFi in lovely Jonesboro
Jonesboro
10.0 out of 10, Exceptional, (3)
"great place. wonderful host."
United States
Carla m.
The price is ￥17,166
￥39,120 total
includes taxes & fees
Dec 14 - Dec 15
Charming 2-bedroom with AC, WiFi in lovely Jonesboro
Terrace/patio
Contemporary Glamping with Native American Appeal!

Contemporary Glamping with Native American Appeal!

Contemporary Glamping with Native American Appeal!
Anna
10.0 out of 10, Exceptional, (102)
"We loved our stay! The accommodations were clean and comfortable. The cabin atmosphere very was relaxing. We will be back. "
United States
Beth C.
The price is ￥24,878
￥48,020 total
includes taxes & fees
Dec 14 - Dec 15
Contemporary Glamping with Native American Appeal!
Outdoor spa tub
Spacious 2 BR, 1 1/2 baths, hot tub, pool table, outside room, full kitchen

Spacious 2 BR, 1 1/2 baths, hot tub, pool table, outside room, full kitchen

Spacious 2 BR, 1 1/2 baths, hot tub, pool table, outside room, full kitchen
Anna
9.8 out of 10, Exceptional, (164)
"Good location to wine trail, very spacious, really enjoyed the hot tub at night!"
United States
Mary K.
Spacious 2 BR, 1 1/2 baths, hot tub, pool table, outside room, full kitchen
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top East Cape Girardeau Hotel Reviews

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

10/10 Excellent
"Very friendly staff and great breakfast"
Ray 1-night trip
Posted 3 days ago
Drury Inn & Suites Cape Girardeau

Find out more about East Cape Girardeau

Search for holiday rentals in East Cape Girardeau on Expedia! You can easily find your home rentals, villas, holiday apartments in East Cape Girardeau using one of the methods below:

  • View our selection of featured holiday rentals in East Cape Girardeau
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Look no further and take a look at our great range of rental properties in East Cape Girardeau!

Frequently asked questions

Are there vacation rentals in East Cape Girardeau?

Yes, there are vacation rentals near well known sights in East Cape Girardeau, or you can select a more secluded option if you'd like a relaxing place to stay.

What are some of the best vacation home rentals that East Cape Girardeau has to offer?

Little Blue Cottage on Spanish: This vacation home near East Cape Girardeau comes with WiFi so you can feel at home during your trip.

What’s there to see and do in East Cape Girardeau?

Explore the area and family-friendly sights such as Cape Splash Family Aquatic Center, or get out into nature at a spot like Cape Rock Park. Isle Casino Cape Girardeau and Southeast Missouri State University are a couple of places you'll find in the larger area.

What’s a vacation rental in East Cape Girardeau like?

A vacation rental is a private property you can book for a couple of days or more in East Cape Girardeau. Vacation rentals offer extras like WiFi and washers and dryers so you'll have everything you need. If you're concerned about a clean environment, a vacation rental can provide a sense of privacy away from shared hotel elevators and busy front desks while still allowing you the excitement and enjoyment of travel. You'll also get more space in a vacation rental than in a traditional hotel, which makes a vacation rental a great option for a small group gathering.