A cityscape with historic buildings, a baseball field, a pedestrian street, and modern architecture.

Find Resorts & Hotels with Spas in Durham, NC

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Check availability on Durham Resorts & Hotels with Spas

Tonight
Oct 8 - Oct 9
Tomorrow
Oct 9 - Oct 10
This weekend
Oct 9 - Oct 11
Next weekend
Oct 16 - Oct 18

Our top choices for Durham hotels with a spa

A massage therapy session in a room with a bed and a massage table.
A hotel entrance with a glass facade, a flagpole, and a person standing in front.
A hallway with wooden paneling, a tiled floor, and three spherical light fixtures.
A modern restaurant with a central bar, high ceiling, and contemporary lighting.

1. 21c Museum Hotel Durham

21c Museum Hotel Durham
Downtown Durham
  • Rejuvenate at this upscale hotel with spa treatment rooms and a sauna near Durham's arts district.
￥24,038
￥28,073 total
includes taxes & fees
Nov 8 - Nov 9
21c Museum Hotel Durham
A lobby with a central round table surrounded by armchairs, a chandelier, and a floral arrangement.
A spacious living room with large windows, multiple seating areas, and a central table with lamps.
An outdoor seating area with a view of a sunset over a forested area.
A dining area with a central table surrounded by chairs, a decorative glass sculpture, and a fireplace in the background.

2. The Umstead Hotel and Spa

The Umstead Hotel and Spa
Cary
  • Discover a spa sanctuary where deep soaking tubs and rejuvenating treatments await in this immaculate luxury resort.
￥59,649
￥67,553 total
includes taxes & fees
Oct 25 - Oct 26
The Umstead Hotel and Spa
View all properties

Choose what matters most at spa hotels in Durham

Pool
Hot tub
Breakfast included
4 stars
5 stars

Top Durham Hotel Reviews

21c Museum Hotel Durham

21c Museum Hotel Durham

10/10 Excellent
"Perfect location. Beautiful place. We especially liked the exhibits (art) throughout. The best French toast ever at brunch!"
Janice 1-night trip
Posted 7 hours ago
21c Museum Hotel Durham
Millennium Hotel Durham

Millennium Hotel Durham

10/10 Excellent
"Staff very friendly and helpful Thankyou Patrick and all of the staff. Comfy beds and atmosphere"
nathan 1-night trip
Posted 11 hours ago
Millennium Hotel Durham
Courtyard Durham Near Duke University/Downtown

Courtyard Durham Near Duke University/Downtown

10/10 Excellent
"Great room, close to downtown. Wonderfully professional staff. Would stay there again."
Deborah 1-night trip
Posted 2 days ago
Courtyard Durham Near Duke University/Downtown
La Quinta Inn & Suites by Wyndham Raleigh/Durham Southpoint

La Quinta Inn & Suites by Wyndham Raleigh/Durham Southpoint

8/10 Good
"El olor de la habitación"
Nadia Gabriela Espinal 1-night trip
Posted 3 days ago
La Quinta Inn & Suites by Wyndham Raleigh/Durham Southpoint
DoubleTree Suites by Hilton Raleigh - Durham

DoubleTree Suites by Hilton Raleigh - Durham

10/10 Excellent
"It was great"
stephanie 2-night trip
Posted 3 days ago
DoubleTree Suites by Hilton Raleigh - Durham

Frequently asked questions

Looking to vacation at a spa hotel in Durham?
Book one of our fantastic spa hotels and pamper yourself from the moment you arrive. Travelers love the array of shops and restaurants in Durham. Spa hotels are a great way to break out of your routine and add a layer of luxury to your holiday.
What's there to see and do in Durham?
Experience Durham and visit Carolina Theatre, Durham Performing Arts Center, and American Tobacco Campus. If you have extra time while you're in the area, you might want to see Durham Bulls Athletic Park and Sarah P. Duke Gardens.
What is a Durham spa hotel?
Spa hotels in Durham provide lodging and have an on-site spa offering services including massages and beauty treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.

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