A cityscape with historic buildings, a baseball field, a pedestrian street, and modern architecture.

Find Resorts & Hotels with Spas in Durham, NC

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Durham Resorts & Hotels with Spas

Tonight
Aug 23 - Aug 24
Tomorrow
Aug 24 - Aug 25
Next weekend
Aug 28 - Aug 30
In two weeks
Sep 4 - Sep 6

Our top choices for Durham hotels with a spa

A massage therapy session in a room with a bed and a massage table.
A modern lobby with a sectional sofa, a coffee table, and a decorative ceiling piece.
A modern restaurant with a central bar, high ceiling, and contemporary lighting.
A hallway with wooden paneling, a tiled floor, and three spherical light fixtures.

1. 21c Museum Hotel Durham

21c Museum Hotel Durham
Downtown Durham
  • Rejuvenate at this upscale hotel with spa treatment rooms and a sauna near Durham's arts district.
￥20,131
￥23,644 total
includes taxes & fees
Sep 12 - Sep 13
21c Museum Hotel Durham
A lobby with a central round table surrounded by armchairs, a chandelier, and a floral arrangement.
A dining area with a central table surrounded by chairs, a decorative glass sculpture, and a fireplace in the background.
An outdoor seating area with a view of a sunset over a forested area.
A spacious living room with large windows, multiple seating areas, and a central table with lamps.

2. The Umstead Hotel and Spa

The Umstead Hotel and Spa
Cary
  • Discover a spa sanctuary where deep soaking tubs and rejuvenating treatments await in this immaculate luxury resort.
￥61,110
￥69,207 total
includes taxes & fees
Sep 10 - Sep 11
The Umstead Hotel and Spa
View all properties

Choose what matters most at spa hotels in Durham

Pool
Hot tub
Breakfast included
4 stars
5 stars

Top Durham Hotel Reviews

Millennium Hotel Durham

Millennium Hotel Durham

8/10 Good
"Y"
Leonard 1-night trip
Posted 12 hours ago
Millennium Hotel Durham
Hilton Durham near Duke University

Hilton Durham near Duke University

8/10 Good
"Nice room, nice windows. But the room smelled musty, which wasn’t the case during prior stays."
Sanjeeve 1-night trip
Posted 12 hours ago
Hilton Durham near Duke University
Sheraton Imperial Hotel Raleigh-Durham Airport/RTP

Sheraton Imperial Hotel Raleigh-Durham Airport/RTP

10/10 Excellent
"The pool was nice my kids had a great time."
Ciearra 1-night trip
Posted 2 days ago
Sheraton Imperial Hotel Raleigh-Durham Airport/RTP
JB Duke Hotel

JB Duke Hotel

10/10 Excellent
"Location excellent for Duke U access"
Michael 1-night trip
Posted 3 days ago
JB Duke Hotel

Frequently asked questions

Looking to vacation at a spa hotel in Durham?
Book one of our fantastic spa hotels and pamper yourself from the moment you arrive. Travelers love the array of shops and restaurants in Durham. Spa hotels are a great way to break out of your routine and add a layer of luxury to your holiday.
What's there to see and do in Durham?
Experience Durham and visit Carolina Theatre, Durham Performing Arts Center, and American Tobacco Campus. If you have extra time while you're in the area, you might want to see Durham Bulls Athletic Park and Brightleaf Square.
What is a Durham spa hotel?
Spa hotels in Durham provide lodging and have an on-site spa offering services including massages and beauty treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.

Explore a world of travel with Expedia