Find Resorts & Hotels with Spas in Durham, NC

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Check availability on Durham Resorts & Hotels with Spas

Tonight
Dec 21 - Dec 22
Tomorrow
Dec 22 - Dec 23
Next weekend
Dec 26 - Dec 28
In two weeks
Jan 2 - Jan 4

Our top choices for Durham hotels with a spa

Aromatherapy, deep-tissue massages, Swedish massages, prenatal massages
21c Museum Hotel Durham

21c Museum Hotel Durham

21c Museum Hotel Durham
4.0 star property
Downtown Durham
8.4 out of 10, Very Good, (1000)
"Amazing staff, comfortable rooms, best shower, convenient location. "
United States
Lauren
The price is ￥25,343
￥29,553 total
includes taxes & fees
Jan 11 - Jan 12, 2026
21c Museum Hotel Durham
Sauna, hot tub, steam room, body treatments, aromatherapy
The Umstead Hotel and Spa

The Umstead Hotel and Spa

The Umstead Hotel and Spa
5.0 star property
Cary
9.6 out of 10, Exceptional, (713)
"Awesome hotel "
United States
Steven
The price is ￥56,907
￥64,447 total
includes taxes & fees
Dec 29 - Dec 30
The Umstead Hotel and Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Durham Hotel Reviews

21c Museum Hotel Durham

21c Museum Hotel Durham

10/10 Excellent
"Good hotel"
Charles 3-night trip
Posted 4 days ago
21c Museum Hotel Durham

Frequently asked questions

Looking to vacation at a spa hotel in Durham?
Book one of our fantastic spa hotels and pamper yourself from the moment you arrive. Travelers love the array of shops and restaurants in Durham. Spa hotels are a great way to break out of your routine and add a layer of luxury to your holiday.
What's there to see and do in Durham?
Experience Durham and visit Carolina Theatre, Durham Performing Arts Center, and American Tobacco Campus. If you have extra time while you're in the area, you might want to see Durham Bulls Athletic Park and Sarah P. Duke Gardens.
What is a Durham spa hotel?
Spa hotels in Durham provide lodging and have an on-site spa offering services including massages and beauty treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.