Downtown Santiago Vacations

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to ¥45,448 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in Downtown Santiago

Find the best Downtown Santiago areas and neighborhoods for the activities you enjoy most. Learn more about Downtown Santiago

Downtown Santiago Hotel Deals

Hotel Plaza San Francisco

Hotel Plaza San Francisco

4 out of 5
Alameda 816 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is ¥19,462 per night from Mar 3 to Mar 4
¥19,462
¥19,462 total
Mar 3 - Mar 4
9.2/10 Wonderful! (1,004 reviews)
Very nice amenities, friendly and helpful staff. Great location. Would definitely recommend.

Reviewed on Feb 28, 2026

Hotel Plaza San Francisco
Almacruz Hotel y Centro de Convenciones

Almacruz Hotel y Centro de Convenciones

4 out of 5
San Antonio 65 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is ¥12,453 per night from Apr 1 to Apr 2
¥12,453
¥12,453 total
Apr 1 - Apr 2
8.2/10 Very Good! (666 reviews)
Hotel staff, from front desk to bell staff, were friendly and helpful even though I don’t speak Spanish.

Reviewed on Feb 21, 2026

Almacruz Hotel y Centro de Convenciones
Le Méridien Santiago

Le Méridien Santiago

4 out of 5
Av. Libertador Bernardo O'Higgins 136 Santiago Region Metropolitana
The price is ¥15,761 per night from Mar 14 to Mar 15
¥15,761
¥15,761 total
Mar 14 - Mar 15
8.4/10 Very Good! (559 reviews)
Everything was excellent, great location, great service, great room, very nice pool and amenities, and wonderful breakfast

Reviewed on Feb 19, 2026

Le Méridien Santiago
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Downtown Santiago vacation package cost?
We make it simple to travel somewhere new, with Downtown Santiago vacation packages starting from just . You'll have the flexibility to combine your preferred airlines, hotels and car rental. For the ultimate getaway, why not add a few tours and activities to your itinerary?
How do I get a cheap travel package to Downtown Santiago?
Combine your bookings with Expedia to save big on your next big adventure. With more than 550 airlines and 1,000,000 properties around the globe, your Downtown Santiago vacation package can be tailored exactly to suit your travel style. With all those extra dollars, why not throw in some interesting activities and tours? It's an easy way to unlock even more savings. Your dream vacation in Downtown Santiago is closer than you thought!
How far in advance should I book my Downtown Santiago vacation?
Search Expedia to compare international flights as soon as possible. In many cases, you can purchase a seat up to 12 months before departure. If you don't see your preferred air carrier, or you've left things to the last moment, don't stress. Cheap fares to Downtown Santiago occasionally appear a few weeks before the date of departure.
What does an Expedia Downtown Santiago travel package include?
Flights, hotels and a cool car for your road trip adventures. Simply pick and choose your preferred bundle and get access to incredible deals. Once you've made your booking, add on some tours and experiences and watch your savings grow. When it comes to organizing your Downtown Santiago trip, the choice is all yours!
What should I know before booking a Downtown Santiago travel package?
When you book your flights, hotels and car rentals together, you'll be rewarded with amazing discounts. Whether you're organizing an outdoor getaway in a chalet or would rather stay in a luxurious city hotel, Expedia will make it happen for less.
Can I choose my airline with a Downtown Santiago Expedia vacation package?
Yes — that's the beauty of an Expedia package. You're the boss! We have access to more than 550 partner airlines all over the world, so you have loads of choice when planning your Downtown Santiago adventure.
If I'm not able to travel, can I cancel my Downtown Santiago vacation package?
You can. We get that things don't always go to plan, so we're here to help if you have to make changes to your Downtown Santiago vacation package. It may be possible to amend or cancel your itinerary at no cost if you've booked within 24 hours. Your hotel, airline or car rental company may impose a fee if your booking was made more than 24 hours ago. Take a look at our Customer Service Portal for more information. Also, check your itinerary for the nitty-gritty on change fees.

Discover the most popular places to visit in Downtown Santiago

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.