Top Downtown Hotels

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Where to stay in Downtown

Find the best Downtown areas and neighborhoods for the activities you enjoy most.

Serenity Bay

Though Serenity Bay might not have many top sights, you can venture to the surrounding area to see attractions like Keowee Key Golf Course and Lake Keowee.

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Pine Ridge Point

While Pine Ridge Point isn't home to many top sights, Lake Keowee and Keowee Key Golf Course are some notable places to visit nearby.

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Indian Oaks

While there might not be top attractions in Indian Oaks, you can explore the larger area and discover places like The Gauntlet and Seneca Historic District.

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Keowee Plantation

When in Keowee Plantation, you can plan a visit to The Gauntlet and Seneca Historic District, some noteworthy sights in the nearby area.

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Top Downtown Hotel Reviews

Quality Inn Seneca Clemson Area US-123

10/10 Excellent

"I liked the cleanliness in the room and the pool area. Fresh towels were given each day. It was a nice place to stay."

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

10/10 Excellent

"This cabin is SMALL and it is well appointed and feels bigger than it is because of the very high ceilings. The bed was comfortable, the room was very clean, the bathroom products smelled good, and the treats were a nice touch. My only real complaint is that we were supposed to receive a text the morning of our arrival with a cabin assignment and key code; we did not receive the text until 30 minutes before check in time. Had we been told that we wouldn't receive it until that time, we would not have worried. As it was, when we didn't receive it, we became concerned that we would not have a place to stay for the evening. It took a number of phone calls and chat sessions to get past AI and find some help."

The Shepherd Hotel Downtown Clemson

10/10 Excellent

"Trip to visit Clemson University campus. Room was beautifully appointed, average size but comfortable. Lobby is gorgeous, southern organic. Restaurant on site great for breakfast and dinner. Employees were calm, friendly and made on feel at home. A nice bar with an indoor area and terrace too."

Inn @ Clemson

10/10 Excellent

"Clemson Inn’s Staff was top tier. I had recently had knee surgery and was one week out supporting my son’s dreams at a football camp at Clemson. The staff was so helpful to me, it was like having my own personal concierge. I needed my ice packs really frozen and the mini fridges in the room wasn’t going to cut it so they would put my ice packs in their freezer and get them every time I needed them. They helped me with my bags. They went above and beyond for me. I’m so grateful. If my son chooses Clemson, this will be my host hotel every time I visit. Thank you to Ashley (Manager), Kenzie, Alex, Victoria and Rahul. You all are simply amazing. I can’t thank you enough."

Frequently asked questions

What is Downtown like?

Travelers to the Downtown neighborhood in Seneca will be sure to enjoy their stay. Be sure to check out The Gauntlet and Seneca Historic District as part of your Downtown travel plans.

Where is the best place to stay in Downtown?

Based on our traveler data, Quality Inn Seneca Clemson Area US-123 is one of the top choices for your stay in Downtown. This hotel offers free breakfast and free parking.

How many hotels can I expect to find in Downtown?

If you're searching for places to stay in Seneca, choose from one of Expedia's 13 hotels and other accommodations in Downtown.

If I need to cancel my hotel reservation in Downtown, will I receive a refund?

Yes! You'll find that most room reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of booking. Enter your dates, click on "Search", then you can filter by "fully refundable" to view the best deals in Downtown.

Where can I learn more about changing or cancelling my trip to Downtown?

To find more details about rescheduling or cancelling your trip to Downtown, head over to our customer service page.

What can I see and do in this Seneca neighborhood?

The Gauntlet, Seneca Historic District, and Blue Ridge Arts Center are just a few attractions to check out in Downtown. As you're discovering the neighborhood, Bertha Lee Strickland Cultural Museum and Oconee County Library Seneca Branch are some other places worth a visit. Seneca City Hall, Golden Corner Plaza, and Oconee Community Theatre are just a few of the places to visit in and around Downtown. While you're out sightseeing in Seneca, be sure to visit other sights like Applewood Shopping Center or Wyndham Plaza.

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Our top choices for Downtown hotels

1. Quality Inn Seneca Clemson Area US-123

2. The Point At Lake Hartwell

3. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

4. Fairfield Inn & Suites Seneca Clemson Univ Area

5. Super 8 by Wyndham Lavonia

6. Best Western Plus Clemson Hotel & Conference Center

7. Lakeside Lodge Clemson

8. Inn @ Clemson

9. Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

10. Rodeway Inn & Suites Walhalla

11. Liberty Hall Bed and Breakfast

12. 2 Mi to Clemson: Central Villa w/ Deck, Near Lakes

13. Hampton Inn & Suites Lavonia

14. Econo Lodge Lavonia I-85

15. Super 8 by Wyndham Anderson/Clemson Area

16. The Inn at Patrick Square

17. Quality Inn Clemson near University

18. Tru by Hilton Seneca Clemson

19. Days Inn by Wyndham Anderson

20. Comfort Inn & Suites Clemson - University Area

Where to stay in Downtown

Serenity Bay

Pine Ridge Point

Indian Oaks

Keowee Plantation

Top Downtown Hotel Reviews

Quality Inn Seneca Clemson Area US-123

Frequently asked questions