Find Boutique Hotels in Downtown Buffalo, NY

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Downtown Buffalo Boutique Hotels

Our top choices for Downtown Buffalo boutique hotels

Lobby
The Giacomo, an Ascend Collection Hotel

The Giacomo, an Ascend Collection Hotel

The Giacomo, an Ascend Collection Hotel
3.0 star property
Downtown Niagara Falls
8.6 out of 10, Excellent, (1003)
"Very friendly staff and beautiful older boutique hotel. "
United States
Tondra
The price is ￥20,039
￥22,843 total
includes taxes & fees
Jan 2 - Jan 3, 2026
The Giacomo, an Ascend Collection Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Downtown Buffalo Hotel Reviews

The Mansion On Delaware Ave

The Mansion On Delaware Ave

10/10 Excellent
"All good."
Irene 1-night trip
Posted 3 days ago
The Mansion On Delaware Ave

Explore a world of travel with Expedia

Frequently asked questions

What's there to see and do in Downtown Buffalo?
Visitors speak positively about this destination's fantastic nightlife, popular theater scene, and great live music. Chippewa District, Statler Tower, and Shea's Performing Arts Center are some of the local sights worth visiting. You might also want to consider exploring Buffalo City Hall, Kleinhans Music Hall, and Ellicott Square Building while you're here.
What's the best way to get to my boutique hotel in Downtown Buffalo?
You have a few options for transportation to and around Downtown Buffalo. The closest major airport is Buffalo Niagara Intl. Airport (BUF), which is located 8 mi (12.9 km) away, but Niagara Falls, NY (IAG-Niagara Falls Intl.) may also be an option. You can walk to nearby metro stations including Fountain Plaza Station, Lafayette Square Station, and Church Station.