Chamberlain, SD

Travel Guide

Photo by Ann Sair
Photo by Ann Sair
Photo by JG Morris
Photo by Nancy Gates
Photo by Amy Beck
Nestled on the banks of the Missouri River, Chamberlain is a town where culture thrives and the great outdoors is never far away. 

Hike through national parks, learn about the lives of the early residents of the area and camp beneath the stars when you visit peaceful Chamberlain.

Step back in time and experience first-hand the life of a Native American when you visit the Akta Lakota Museum & Cultural Center. The exhibition center features a mini theater and interactive displays that focus on both the historical life of these Plains Indians and their modern issues. Shop for local arts and crafts in the gift shop. Purchase a star quilt handmade by Lakota women.

Just outside the city, the Lewis and Clark Interpretive Center brings the two explorers’ epic journey through South Dakota to life. Review the panels and exhibits documenting the two men’s expedition. View the river from the bow of a replica keelboat. The center is located at the 264 mile marker along the I-90 interstate highway.

Experience the Great Plains at the Roam Free Park. Enjoy scenic walks and see an array of local wildlife along the banks of the river. To see the area through the eyes of an explorer, follow the short Lewis and Clark Trail, a scenic route alongside the river. Whatever your biking skill level, enjoy cycling along the trail. 

The Missouri River is the lifeblood of the town. Find a spot at the American Creek Campground on the water’s edge for a spectacular way to experience river life. Space for tents and RVs is plentiful and facilities at the site are excellent. If you are feeling active, rent a boat or kayak and enjoy a unique view of Chamberlain and neighboring Oacoma. Swim at the riverside beach or try fishing for walleye. 

For those who prefer being in the center of town, stay at one of the family-run accommodations offering excellent service. Many are within walking distance of superb local restaurants where you can refuel, ready for another day of enjoying the great outdoors.

AmericInn by Wyndham Chamberlain - Conference Center

AmericInn by Wyndham Chamberlain - Conference Center

2.5 out of 5
1981 East King Street, Chamberlain, SD
The price is ¥21,897 per night from Sep 25 to Sep 26
¥21,897
¥24,098 total
Sep 25 - Sep 26
includes taxes & fees
Book a stay at this business-friendly hotel in Chamberlain. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (1,013 reviews)
"Nice and clean rooms !"

Reviewed on Sep 15, 2025

AmericInn by Wyndham Chamberlain - Conference Center
Super 8 by Wyndham Chamberlain SD

Super 8 by Wyndham Chamberlain SD

2 out of 5
Box 36 Lakeview Heights, I 90 Exit 263, Chamberlain, SD
The price is ¥12,073 per night from Oct 8 to Oct 9
¥12,073
¥13,420 total
Oct 8 - Oct 9
includes taxes & fees
Book a stay at this business-friendly motel in Chamberlain. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8/10 Very Good! (1,013 reviews)
"Great for an overnight stay."

Reviewed on Sep 18, 2025

Super 8 by Wyndham Chamberlain SD
Best Western Lee's Motor Inn

Best Western Lee's Motor Inn

2.5 out of 5
220 W King Avenue, Chamberlain, SD
The price is ¥13,611 per night from Oct 3 to Oct 4
¥13,611
¥15,092 total
Oct 3 - Oct 4
includes taxes & fees
Book a stay at this golf hotel in Chamberlain. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in ...
8.2/10 Very Good! (964 reviews)
"The staff was very accommodating and pleasantly friendly. The breakfast area was clean and fully stocked with food and supplies. The room was quiet and for being an older place, it was very well maintained. I would not hesitate to recommend this motel to anyone."

Reviewed on Sep 16, 2025

Best Western Lee's Motor Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Log Cabin located minutes from Missouri River, airport, I-90,  and downtown.

Log Cabin located minutes from Missouri River, airport, I-90, and downtown.

Chamberlain
Book a stay at this family-friendly cabin in Chamberlain. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions Lewis and Clark Interpretive ...
10/10 Exceptional! (76 reviews)
"Just as good as last year and we all had a great time and everything on our mission trip to Crow Creek Reservation went well. Hope we can do this again in 2026. Could not think of a better place to stay."

Reviewed on Sep 2, 2025

Log Cabin located minutes from Missouri River, airport, I-90, and downtown.
Missouri River Get Away For Your Fishing, Hunting and Family Adventures

Missouri River Get Away For Your Fishing, Hunting and Family Adventures

Chamberlain
Stay at this vacation home in Chamberlain. Enjoy free WiFi, an in-room coffeemaker, and air conditioning. Popular attractions Cozard Memorial Library and Chamberlain ...
9.8/10 Exceptional! (55 reviews)
"Great place! Has everything you need for hunting and fishing!"

Reviewed on Sep 2, 2025

Missouri River Get Away For Your Fishing, Hunting and Family Adventures
Location Location Location!  On a river view acreage, sleeps up to 14, pets  ok.

Location Location Location! On a river view acreage, sleeps up to 14, pets ok.

Chamberlain
Stay at this vacation home in Chamberlain. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions Roam Free Park and Akta Lakota Museum And Cultural ...
9.8/10 Exceptional! (24 reviews)
"Easy communication, great views"

Reviewed on Aug 26, 2025

Location Location Location! On a river view acreage, sleeps up to 14, pets ok.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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