The Best Resorts & Hotels with Spas in Brindisi from ￥15,090 in 2026

Check availability on Brindisi Resorts & Hotels with Spas

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Our top choices for Brindisi hotels with a spa

Deluxe Double Room, Balcony, City View | Spa | Sauna, hot tub

1. Centrale Suites

Brindisi Historic Center

￥15,090 total

includes taxes & fees

Aug 19 - Aug 20

2. Dimora Nettare

Brindisi Historic Center

Soothe away stress at this rejuvenating affittacamere featuring Swedish, Thai, and hot stone massages near Port of Brindisi.

￥22,508 total

includes taxes & fees

Aug 31 - Sep 1

Luxury Studio Suite (1) | Egyptian cotton sheets, premium bedding, down comforters, desk

3. FILIA SOLIS - Old Town SUITEs & SPA

Brindisi Historic Center

Relax in the heart of Old Town Brindisi with private hot tubs and luxurious massages at this spa-focused aparthotel retreat.

￥24,879 total

includes taxes & fees

Aug 4 - Aug 5

4. Masseria Elysium

Mesagne

Rejuvenate at this Mediterranean farm stay offering indulgent spa services, a hot tub, and a sauna amid serene garden landscapes.

￥34,396 total

includes taxes & fees

Sep 3 - Sep 4

5. Tenuta Moreno

Mesagne

Relax and rejuvenate at this Beaux Arts hotel with a full-service spa offering aromatherapy and Ayurvedic treatments.

￥24,626 total

includes taxes & fees

Aug 5 - Aug 6

Double Room, 1 Double Bed (SPA access) | Treatment room | Couples treatment rooms, sauna, hot tub, steam room, body treatments

6. Tenute Al Bano

Cellino San Marco

Enjoy rejuvenating treatments at this rural retreat with couples spa rooms, an outdoor pool, and an attached winery for a complete escape.

￥27,117 total

includes taxes & fees

Aug 31 - Sep 1

7. Villa Neviera - Wine Resort and Spa

San Donaci

Unwind in a full-service spa villa nestled within a wine resort, where garden views and vineyard experiences create a restorative retreat.

￥20,209 total

includes taxes & fees

Aug 5 - Aug 6

Turkish bath, body treatments, hydrotherapy, aromatherapy

8. Masseria Messapia Wine Resort & SPA

Mesagne

Luxurious Turkish bath and deep-tissue massages await at this winery resort with private beach access.

￥59,205 total

includes taxes & fees

Sep 1 - Sep 2

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Breakfast included

Top Brindisi Hotel Reviews

Ostuni a Mare

10/10 Excellent

"The property is even better than advertised! It is a gorgeous resort and very convenient for young families. The little train will take you to the private beach in minutes. The 3 pools are wonderful, but the most noteworthy thing to mention is the incredible staff!!! Amazing, attentive, always busy and making sure that the guests have everything. There is nothing I did not like (except maybe the security guard at the villas’ gate who was extremely rude because we were at the wrong gate to exit)… My husband and I would come back and recommend it wholeheartedly!"

Hotel Orientale

10/10 Excellent

"The Hotel Orientale in Brindisi is a very good place to stay, The rooms are clean, the property is well maintained. The hotel is very well located - just a couple of blocks from the scenic seafront promenade that is perfect for dinning, having coffee or a gelato and watching the sunset. The hotel has a nice breakfast buffet. The hotel staff was also very attentive. Furthermore, the hotel has parking - which was a must for us as we had a car. There is Taxi stand right in front of the hotel that you can use only to unload your luggage and check in. At that time, you will give your car key to the assistant who will park the car for you. There are many stores around the hotel and places to have coffee, gelato, and snacks. Additionally, there are plenty of things to see and do in Brindisi which can take you a full day. The main sites worth visiting include: the Duomo (Cathedral of Brindisi); the Church (Chiesa) of San Giovanni; The Chiesa of San Benedetto; the Ribezzo Archeological Museum; the Palazoo Granasfei Nervagna; and the Monument to Italian Sailors (which you must take the ferry over to the other side of Brindisi less than 2 Euros per ride). All sites in Brindisi are walking distance from the hotel - but you must like to walk if you want to see the Swavian Castle from the outside- which is closed to the public as it is now a Navy base. Furthermore, if you want to visit the Castello Alfonsino - it might not be possible as it requires calling and making a reservation."

Hilton Garden Inn Lecce

10/10 Excellent

"The hotel was extremely dog friendly, which was a relief for me. When you’re traveling with your service pet and you’re constantly being questioned overseas if it’s actually a service pet or if you have a lap dog it becomes anxious making all the time. So, when I walk into a beautiful hotel that welcomes you with a smile and welcomed your pet with a smile it’s such a relief!!! Thank you for the wonderful stay."

Frequently asked questions

Looking for a spa hotel in Brindisi?

Book one of our fantastic spa hotels and treat yourself from the moment you arrive. Check out the historical sites and museums in Brindisi—your cultural tour starts here. Enjoy the theaters and natural parks during your vacation. Hotels with spas are a great way to take a break from your routine and add a layer of luxury to your vacation.

What is the best spa hotel in Brindisi?

Centrale Suites

How many spa hotels will I find in Brindisi?

Among Expedia's 195 accommodation options in Brindisi, there is 1 spa hotel.

What's there to see and do in Brindisi?

Experience Brindisi with a stop at Italian Sailor Monument, Court of Brindisi, and Port of Brindisi. If you have spare time during your trip, you might want to make a stop at Hemingway Beach and Riserva Natural Torre Guacceto.

What is a Brindisi spa hotel?

Spa hotels in Brindisi provide lodging and have a full on-site spa offering services including facials as well as body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.

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Check availability on Brindisi Resorts & Hotels with Spas

Our top choices for Brindisi hotels with a spa

1. Centrale Suites

2. Dimora Nettare

3. FILIA SOLIS - Old Town SUITEs & SPA

4. Masseria Elysium

5. Tenuta Moreno

6. Tenute Al Bano

7. Villa Neviera - Wine Resort and Spa

8. Masseria Messapia Wine Resort & SPA

9. Le Scuderie - Castello Monaci

10. Ostuni Palace Hotel Ristorante & SPA

Choose what matters most at spa hotels in Brindisi

Top Brindisi Hotel Reviews

Ostuni a Mare

Patria Palace Hotel Lecce - Leading Hotels of the World

Hotel Orientale

Hilton Garden Inn Lecce

Ostuni Palace Hotel Ristorante & SPA

Frequently asked questions

Explore a world of travel with Expedia

Find Resorts & Hotels with Spas in Brindisi

Change your mind

Treat yourself

Be picky

Check availability on Brindisi Resorts & Hotels with Spas

Our top choices for Brindisi hotels with a spa

1. Centrale Suites

2. Dimora Nettare

3. FILIA SOLIS - Old Town SUITEs & SPA

4. Masseria Elysium

5. Tenuta Moreno

6. Tenute Al Bano

7. Villa Neviera - Wine Resort and Spa

8. Masseria Messapia Wine Resort & SPA

9. Le Scuderie - Castello Monaci

10. Ostuni Palace Hotel Ristorante & SPA

Choose what matters most at spa hotels in Brindisi

Top Brindisi Hotel Reviews

Ostuni a Mare

Frequently asked questions

Explore a world of travel with Expedia