Find All Southwest Illinois Hotels
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Find All Southwest Illinois Hotels
We have found 766 Southwest Illinois Hotels
- Drury Plaza Hotel Mt. Vernon
- Drury Inn & Suites St. Louis Fairview Heights
- Super 8 by Wyndham O'Fallon
- Drury Inn & Suites St. Louis O'Fallon, IL
- Walker's Bluff Casino Resort
- Drury Inn & Suites Marion
- The Principal Hotel
- Welcome Suites
- Comfort Suites Mount Vernon
- Drury Inn & Suites St. Louis Collinsville
- Holiday Inn Express & Suites Mount Vernon by IHG
- Quality Inn & Suites near St. Louis and I-255
- Super 8 by Wyndham Troy IL/St. Louis Area
- Quality Inn O'Fallon IL - St. Louis
- Comfort Suites Fairview Heights - St. Louis
- Comfort Inn Edwardsville - St. Louis
- Red Lion Inn & Suites Pontoon Beach
- Radisson Hotel Fairview Heights - St. Louis
- Best Western Marion Hotel
- Sleep Inn O'Fallon near I-64
- Best Western Plus MidAmerica Hotel
- Quality Inn & Suites Vandalia near I-70 and Hwy 51
- Best Western Troy Hotel
- Comfort Inn Collinsville near St. Louis
- Holiday Inn Express & Suites Carbondale - University Area by IHG
- Baymont by Wyndham Marion
- Best Western Saluki Inn
- Super 8 by Wyndham Mt. Vernon IL
- Holiday Inn Express & Suites Edwardsville by IHG
- DoubleTree by Hilton Collinsville - St. Louis
- Country Inn & Suites by Radisson, Fairview Heights, IL
- Comfort Inn & Suites O'Fallon - St. Louis Area
- Holiday Inn Express Troy by IHG
- Super 8 by Wyndham Fairview Heights-St. Louis
- La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
- DoubleTree by Hilton Mt. Vernon
- Red Lion Inn & Suites Caseyville
- Best Western St. Louis Fairview Heights
- SureStay Hotel by Best Western Whittington Rend Lake
- Country Inn & Suites by Radisson, Marion, IL
- Comfort Inn & Suites Marion I-57
- Motel 6 Caseyville, IL - Caseyville Il
- Quality Inn Mount Vernon, IL
- Hampton Inn O'Fallon
- Super 8 by Wyndham Marion
- Days Inn by Wyndham Mount Vernon
- Super 8 by Wyndham Carbondale
- Best Western Plus Pontoon Beach
- Hampton Inn St. Louis - Columbia
- Motel 6 Marion, IL
- Quality Inn & Suites Marion
- Baymont by Wyndham O'Fallon St. Louis Area
- La Quinta Inn & Suites by Wyndham Pontoon Beach
- Indian Mound Motel
- Quality Inn & Suites Caseyville - St. Louis
- Motel 6 Mount Vernon, IL
- Home2 Suites by Hilton Carbondale
- Royal Relax Inn
- Fairfield Inn by Marriott St. Louis Collinsville, IL
- Holiday Inn Express & Suites O'Fallon/Shiloh by IHG
- Holiday Inn Express Hotel & Suites Marion Northeast by IHG
- Country Hearth Inn & Suites Edwardsville St. Louis
- Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
- Econo Lodge Inn & Suites Fairview Heights - St. Louis
- Extended Stay America Select Suites - St. Louis - O' Fallon, IL
- Red Roof Inn St Louis - Troy, IL
- Baymont by Wyndham Chester IL
- Holiday Inn Express & Suites Vandalia by IHG
- Quality Inn Carbondale University area
- Days Inn by Wyndham Salem, Illinois
- Fairgrounds Inn
- Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City
- Bel Air Motel
- Econo Lodge Inn & Suites Granite City - St. Louis
- Hampton Inn Carbondale
- Seasons Inn & Suites Highland
- Americas Best Value Inn West Frankfort
- Days Inn by Wyndham Pontoon Beach
- Holiday Inn Express & Suites Salem by IHG
- Super 8 by Wyndham Collinsville St. Louis
- Pinckeyville Inn and Suites
- Best Western Plus Centralia Hotel & Suites
- Quality Inn & Suites Salem near I-57
- Super 8 by Wyndham Belleville St. Louis Area
- Comfort Inn & Suites Carbondale University Area
- Country Garden & Suites
- Hilton Garden Inn St. Louis Shiloh/O'Fallon IL
- University Inn of Carbondale by Hotel O
- Motel 6 Troy, IL
- Comfort Inn & Suites Greenville I-70
- Super 8 by Wyndham Greenville
- Holiday Inn Express Hotel & Suites Sparta by IHG
- Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake
- Fairfield Inn and Suites by Marriott Marion
- Laketree Inn And Suites Marion
Let Expedia take you to the best Hotels in Southwest Illinois. You'll find the largest selection of hotel deals, discount prices, and cheap hotel rates on reservations anywhere in the world. Expedia, the leader in world travel, gives you customer reviews, maps, and the best selection of hotels near landmarks and attractions.