Find All Southwest Illinois Hotels
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Find All Southwest Illinois Hotels
We have found 745 Southwest Illinois Hotels
- Drury Inn & Suites St. Louis Fairview Heights
- Drury Inn & Suites Marion
- Drury Plaza Hotel Mt. Vernon
- Drury Inn & Suites St. Louis O'Fallon, IL
- Super 8 by Wyndham O'Fallon
- Comfort Suites Mount Vernon
- Quality Inn O'Fallon IL - St. Louis
- Comfort Suites Fairview Heights - St. Louis
- Red Lion Inn & Suites Pontoon Beach
- Americas Best Value Inn Collinsville St. Louis
- Super 8 by Wyndham Troy IL/St. Louis Area
- Country Inn & Suites by Radisson, Fairview Heights, IL
- Baymont by Wyndham Marion
- Seasons Inn & Suites Highland
- La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis
- Drury Inn & Suites St. Louis Collinsville
- Holiday Inn Express & Suites Mount Vernon by IHG
- Country Hearth Inn & Suites Edwardsville St. Louis
- Quality Inn & Suites near St. Louis and I-255
- Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City
- Walker's Bluff Casino Resort
- Sleep Inn O'Fallon near I-64
- DoubleTree by Hilton Collinsville - St. Louis
- Red Roof Inn St Louis - Troy, IL
- La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
- Best Western Plus MidAmerica Hotel
- Baymont by Wyndham O'Fallon St. Louis Area
- Super 8 by Wyndham Carbondale
- Holiday Inn Express Troy by IHG
- Best Western Plus Pontoon Beach
- Quality Inn And Suites
- Super 8 by Wyndham Fairview Heights-St. Louis
- Welcome Suites
- Best Western Marion Hotel
- Holiday Inn Express & Suites Edwardsville by IHG
- DoubleTree by Hilton Mt. Vernon
- Fairgrounds Inn
- Fairfield Inn & Suites by Marriott O'Fallon, IL
- Holiday Inn Carbondale-Conference Center by IHG
- Comfort Inn & Suites O'Fallon - St. Louis Area
- Econo Lodge & Suites Granite City
- Home2 Suites by Hilton Carbondale
- La Quinta Inn & Suites by Wyndham Pontoon Beach
- Best Western Saluki Inn
- Quality Inn & Suites Caseyville - St. Louis
- Comfort Inn & Suites Marion I-57
- The Principal Hotel
- Baymont by Wyndham Chester IL
- Econo Lodge Inn & Suites Fairview Heights - St. Louis
- Days Inn by Wyndham Mount Vernon
- Radisson Hotel Fairview Heights - St. Louis
- Holiday Inn Express & Suites - O'Fallon /Shiloh by IHG
- Comfort Inn Collinsville near St. Louis
- Super 8 by Wyndham Mt. Vernon IL
- Country Inn & Suites by Radisson, Marion, IL
- Hilton Garden Inn St. Louis Shiloh/O'Fallon IL
- Quality Inn & Suites Vandalia near I-70 and Hwy 51
- Holiday Inn Express Hotel & Suites Marion Northeast by IHG
- Holiday Inn Express Hotel & Suites Sparta by IHG
- Hampton Inn St. Louis - Columbia
- Red Lion Inn & Suites Caseyville
- Hampton Inn O'Fallon
- Hampton Inn Carbondale
- Comfort Inn Edwardsville - St. Louis
- Super 8 by Wyndham Marion
- Hampton Inn & Suites St. Louis-Edwardsville
- University Inn of Carbondale
- Super 8 by Wyndham Belleville St. Louis Area
- Motel 6 Marion, IL
- Days Inn by Wyndham Salem, Illinois
- Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
- Quality Inn & Suites Salem near I-57
- Best Western Plus Centralia Hotel & Suites
- Quality Inn Mount Vernon, IL
- Best Western Troy Hotel
- Super 8 by Wyndham Collinsville St. Louis
- Extended Stay America Select Suites - St. Louis - O' Fallon, IL
- TownePlace Suites by Marriott St. Louis O'Fallon
- Royal Relax Inn
- Loyalty Inn Maryville
- SureStay Hotel by Best Western Whittington Rend Lake
- Comfort Inn & Suites Greenville I-70
- Holiday Inn Express & Suites Vandalia by IHG
- Super 8 by Wyndham Pontoon Beach IL/St. Louis MO Area
- Motel 6 Caseyville, IL - Caseyville Il
- Motel 6 Mount Vernon, IL
- Indian Mound Motel
- Comfort Inn & Suites Carbondale University Area
- Holiday Inn Express & Suites Salem by IHG
- Best Western St. Louis Fairview Heights
- TownePlace Suites by Marriott St. Louis Edwardsville, IL
- Days Inn by Wyndham Pontoon Beach
- Super 8 by Wyndham Greenville
- Fairfield Inn by Marriott St. Louis Collinsville, IL
- Hampton Inn Collinsville
Let Expedia take you to the best Hotels in Southwest Illinois. You'll find the largest selection of hotel deals, discount prices, and cheap hotel rates on reservations anywhere in the world. Expedia, the leader in world travel, gives you customer reviews, maps, and the best selection of hotels near landmarks and attractions.