Penrose, MO
St. Louis
Popular places to visit
St. Louis Union Station
You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's acclaimed art scene or attend a baseball game.
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.
Gateway Arch
Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.
St. Louis Zoo
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
City Museum
This quirky children’s museum invites visitors to crawl through whales, climb into tree houses and whiz down three-story slides.
Forest Park
Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit.
Things to do
St. Louis Ghost Tour: Sinister Sins & Shadows
Private Tour of St. Louis's Iconic BBQ Joints & Breweries
Best of St. Louis Small Group Tour w/ Arch & River Cruise
St Louis Self-Guided Driving and Walking Audio Tour
St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour
Penrose Hotel Deals
Hyatt Regency St. Louis at The Arch
Clean, comfortable room. Great location.
Reviewed on Jan 5, 2026
Hampton Inn St. Louis-Downtown (At the Gateway Arch)
Awesome location to the Gateway National Arch, Economy Museum, and dome. Loved the friendly staff! The building was very secure and safe feeling with my family in the city. The breakfast area is very well kept and kept stocked well.
Reviewed on Jan 5, 2026
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Room was very nice, clean, staff was great!
Reviewed on Jan 5, 2026
21C Museum Hotel St Louis
Great staff and very clean room.
Reviewed on Jan 5, 2026
Clayton Plaza Hotel & Extended Stay
The room was very cozy and welcoming. The staff was great and friendly from checking in to the breakfast host to checking out.
Reviewed on Jan 5, 2026
Drury Plaza Hotel St. Louis at the Arch
The room, the service, the location, top notch.
Reviewed on Jan 5, 2026
Other neighborhoods around Penrose
Central West End
Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.
Midtown
While you're in Midtown, take in top sights like Chaifetz Arena and jump on the metro at Grand Station to see more of the city.
The Grove
The Grove might not have many top sights, but St. Louis Science Center and Missouri Botanical Gardens and Arboretum are two attractions nearby that you can check out.
Downtown West
If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.
The Gate
While there might not be top attractions in The Gate, you can explore the larger area and discover places like St. Louis Union Station and Busch Stadium.
Lafayette Square
The restaurants and shopping are a few reasons travelers visit Lafayette Square. Though there aren't many top sights in the neighborhood, you can visit St. Louis Union Station and Busch Stadium, a few notable attractions nearby.
