Penrose, MO
St. Louis
Visit Penrose
Stay near popular Penrose attractions
Things to do
Private Tour of St. Louis's Iconic BBQ Joints & Breweries
StL's Signature "Sights and Bites" - Private Tour in St. Louis
St. Louis Ghost Tour: Sinister Sins & Shadows
Lemp Haunted Neighborhood Walking Tour
Downtown St. Louis Smartphone Guided Audio Walking Tour App
Penrose Hotel Deals
Hyatt Regency St. Louis at The Arch
"There were several eating options at the hotel! I loved the views from my room and the walkability."
Reviewed on Jul 23, 2026
Clayton Plaza Hotel & Extended Stay
"Water drain in the bathroom had issues."
Reviewed on Jul 23, 2026
Hollywood Casino & Hotel St. Louis
Pear Tree Inn St. Louis Airport
"As many travelers mentioned, this was a great hotel. Renovated room was not only the cleanest but also functional -- to say nothing of plenty of hot water for a shower and drainage for the bathroom. Small refrigerator and microwave allows us to take every dinner in the room. But, the real highlight ..."
Reviewed on Jul 23, 2026
Forest Park Hotel by MDR
"Room was disgusting. Staff literally was answering their personal phones (at least 3 different times) while helping people. It smelled atrocious. Mattresses has giant stains on them. Mattresses had crumbs on them. The floor was sticky. No way the mini fridge has ever been cleaned.. stains ..."
Reviewed on Jul 22, 2026
Drury Plaza Hotel St. Louis at the Arch
"Very nice stay! Will be back next trip to St Louis"
Reviewed on Jul 23, 2026
Where to stay in Penrose
Downtown St. Louis
Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Gateway Arch or Busch Stadium might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.
Clayton
Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.
Downtown West
If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.
Central West End
The ample dining options and lush forests are just a few popular features of the neighborhood. Make a stop by World Chess Hall of Fame or Blue Strawberry while you're visiting, and jump aboard the metro at Central West End Station to get around town.
Creve Coeur
Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.
