Photo by Deidree DeHart

Find hotels in Six Mile, SC from ￥8,994

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Dec 15 - Dec 16
Tomorrow
Dec 16 - Dec 17
This weekend
Dec 19 - Dec 21
Next weekend
Dec 26 - Dec 28

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Six Mile hotels

House (1 Bedroom) | Interior
Lake Keowee Access: Idyllic Six Mile Cabin!

Lake Keowee Access: Idyllic Six Mile Cabin!

Lake Keowee Access: Idyllic Six Mile Cabin!
3.0 star property
Six Mile
The price is ￥9,972
￥41,220 total
includes taxes & fees
Dec 22 - Dec 23
Lake Keowee Access: Idyllic Six Mile Cabin!
Reception
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
2.5 star property
Anderson
9.0 out of 10, Wonderful, (582)
Just off I-85 with free breakfast, WiFi, and parking, this comfortable hotel sits close to Regal Starlight and Anderson Civic Center. The fitness center offers workout options while the helpful staff ensures a pleasant business or leisure stay.
"It was great. Room was clean and staff was friendly. "
United States
Veronica
The price is ￥16,048
￥17,812 total
includes taxes & fees
Dec 19 - Dec 20
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
Aerial view
Lakeside Lodge Clemson

Lakeside Lodge Clemson

Lakeside Lodge Clemson
2.5 star property
Seneca
9.0 out of 10, Wonderful, (1001)
Relax at this Seneca hotel featuring a seasonal outdoor pool, poolside bar, and hot tub. Located near Lake Keowee and Clemson University, guests enjoy the 24-hour fitness center, restaurant, and bar. Clean rooms, helpful staff, and free WiFi and parking complete your stay.
"Great place to stay. "
United States
Gene
The price is ￥16,983
￥21,082 total
includes taxes & fees
Dec 19 - Dec 20
Lakeside Lodge Clemson
Exterior
Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson
2.0 star property
Anderson
7.8 out of 10, Good, (1002)
Peaceful respite featuring a complimentary continental breakfast and free parking. Located near Regal Starlight and Anderson Civic Center, this hotel delivers relaxing stays with comfortable beds. Helpful staff ensures a restful experience.
"Very nice we'll stay there again"
United States
Michael
The price is ￥9,800
￥10,878 total
includes taxes & fees
Dec 17 - Dec 18
Days Inn by Wyndham Anderson
Exterior
Hampton Inn Anderson/ Alliance Business Park

Hampton Inn Anderson/ Alliance Business Park

Hampton Inn Anderson/ Alliance Business Park
2.5 star property
Anderson
9.2 out of 10, Wonderful, (806)
Free breakfast and WiFi await at this Anderson hotel near Anderson Motor Speedway. Jump into the seasonal outdoor pool or get energized in the 24-hour fitness center. Guests rave about the helpful staff and pristine rooms.
"Very comfortable stay convenient to Greenville Spartanburg Airport."
United States
Rick
The price is ￥16,079
￥17,848 total
includes taxes & fees
Dec 21 - Dec 22
Hampton Inn Anderson/ Alliance Business Park
Lobby
Baymont by Wyndham Easley/Greenville

Baymont by Wyndham Easley/Greenville

Baymont by Wyndham Easley/Greenville
2.5 star property
Easley
7.4 out of 10, Good, (752)
"Nice staff Cleanness Great price"
United States
Sharon
The price is ￥11,686
￥12,970 total
includes taxes & fees
Dec 16 - Dec 17
Baymont by Wyndham Easley/Greenville
Lobby
Microtel Inn & Suites by Wyndham Anderson/Clemson

Microtel Inn & Suites by Wyndham Anderson/Clemson

Microtel Inn & Suites by Wyndham Anderson/Clemson
2.0 star property
Anderson
8.2 out of 10, Very Good, (1001)
Set in Anderson, this welcoming hotel provides a seasonal outdoor pool and complimentary perks including WiFi, parking, and daily continental breakfast. Close to Regal Starlight and Anderson Civic Center, with Clemson University just a short drive away.
"Clean room, staff nice"
United States
Selena
The price is ￥12,449
￥13,820 total
includes taxes & fees
Dec 21 - Dec 22
Microtel Inn & Suites by Wyndham Anderson/Clemson
Lobby
Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
2.5 star property
Clemson
8.2 out of 10, Very Good, (1001)
This business-friendly hotel offers a seasonal outdoor pool and fitness center just 15 minutes from campus. Enjoy free breakfast and parking while exploring nearby African American Museum and Waterfront Park. Guests praise the helpful staff and clean rooms.
"Great stay "
United States
Linda
The price is ￥14,436
￥16,024 total
includes taxes & fees
Dec 21 - Dec 22
Comfort Inn & Suites Clemson - University Area
Reception hall
The Inn at Patrick Square

The Inn at Patrick Square

The Inn at Patrick Square
3.5 star property
Clemson
9.8 out of 10, Exceptional, (784)
Located in Clemson, this inviting inn offers complimentary perks including WiFi, wired internet, and self parking. Just a 5-minute drive from Clemson University, the hotel features clean rooms and a 24-hour front desk. Nearby attractions include the Clemson Area African American Museum.
"Clean room. Nice front desk concierge. Very cute hotel"
United States
Anisha
The price is ￥23,216
￥25,771 total
includes taxes & fees
Dec 16 - Dec 17
The Inn at Patrick Square
Free daily on-the-go breakfast
Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123
2.5 star property
Downtown
8.0 out of 10, Very Good, (665)
Tranquil haven near Clemson University with easy access to local attractions. Enjoy the seasonal outdoor pool, free WiFi, parking, and daily breakfast. Guests praise the helpful staff, clean rooms, and peaceful setting close to restaurants and stores.
"Friendly check in, clean room."
United States
connie
The price is ￥11,451
￥13,526 total
includes taxes & fees
Dec 21 - Dec 22
Quality Inn Seneca Clemson Area US-123
Free buffet breakfast
Country Inn & Suites by Radisson, Anderson, SC

Country Inn & Suites by Radisson, Anderson, SC

Country Inn & Suites by Radisson, Anderson, SC
2.5 star property
Anderson
8.4 out of 10, Very Good, (1000)
This business-friendly hotel offers free breakfast, WiFi, and parking near Lake Hartwell. Take a refreshing dip in the indoor pool or maintain your routine at the fitness center. Located within walking distance of the lake and close to local attractions.
"Clean room, staff was freiendly."
United States
Sherie
The price is ￥17,388
￥19,300 total
includes taxes & fees
Dec 22 - Dec 23
Country Inn & Suites by Radisson, Anderson, SC
Exterior
Holiday Inn Express Anderson by IHG

Holiday Inn Express Anderson by IHG

Holiday Inn Express Anderson by IHG
2.5 star property
Anderson
8.6 out of 10, Excellent, (384)
This quiet Anderson hotel offers free breakfast and parking near Anderson Motor Speedway. Enjoy a refreshing dip in the outdoor pool or workout in the fitness center. Helpful staff and peaceful atmosphere ensure a comfortable stay.
"Convenient location to I-85, quiet with nice parking area "
United States
Nancy
The price is ￥16,360
￥18,160 total
includes taxes & fees
Dec 19 - Dec 20
Holiday Inn Express Anderson by IHG
Exterior
Hilton Garden Inn Anderson

Hilton Garden Inn Anderson

Hilton Garden Inn Anderson
3.0 star property
Anderson
9.0 out of 10, Wonderful, (676)
Escape to this tranquil hotel near Anderson Civic and Sports Center with an indoor pool for year-round swimming. Comfortable rooms include refrigerators and microwaves. Enjoy Garden Grille dining, the bar, and easy access to local attractions.
"Staff were great. Room was clean."
United States
gary
The price is ￥16,079
￥17,848 total
includes taxes & fees
Dec 21 - Dec 22
Hilton Garden Inn Anderson
Reception
Quality Inn Clemson near University

Quality Inn Clemson near University

Quality Inn Clemson near University
2.5 star property
Anderson
7.0 out of 10, Good, (890)
This business-friendly hotel offers a seasonal outdoor pool, terrace, and garden. Located near Anderson Civic Center and Mall with complimentary breakfast, WiFi and parking. Reviews highlight the exceptionally helpful staff for a pleasant stay.
"Bueno was "
Mexico
Alejandro
The price is ￥7,847
￥8,709 total
includes taxes & fees
Dec 23 - Dec 24
Quality Inn Clemson near University
Two queen beds nonsmoking | In-room safe, desk, blackout drapes, iron/ironing board
Hampton Inn Easley

Hampton Inn Easley

Hampton Inn Easley
2.5 star property
Easley
9.4 out of 10, Exceptional, (681)
Enjoy a refreshing morning swim, then drive to nearby Falls Park on the Reedy or The Peace Center. This hotel offers free breakfast, WiFi, and parking. After exploring local attractions, return to comfortable accommodations with attentive staff ready to assist.
"Friendly staff, very comfortable room, excellent hot breakfast."
United States
Thomas
The price is ￥21,464
￥23,824 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Hampton Inn Easley
Outdoor pool
Baymont by Wyndham Anderson Clemson

Baymont by Wyndham Anderson Clemson

Baymont by Wyndham Anderson Clemson
2.5 star property
Anderson
7.0 out of 10, Good, (842)
Just 16 minutes from Clemson Station, this welcoming hotel offers an outdoor pool, 24-hour fitness center, and complimentary amenities including breakfast, WiFi, and parking. Clean rooms provide a peaceful retreat after exploring nearby Regal Starlight and Anderson Civic Center.
"Well lit parking and safe area around the hotel"
United States
Gregory
The price is ￥9,271
￥10,291 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Baymont by Wyndham Anderson Clemson
Property amenity
Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
2.5 star property
Clemson
8.2 out of 10, Very Good, (1004)
Located just 5 minutes from campus with nearby African American Museum and Waterfront Park, this hotel offers free breakfast and parking. Guests love the seasonal outdoor pool, helpful staff, quiet atmosphere, and clean rooms, plus easy walking to Clemson Station.
" Clean room, breakfast, staff very nice."
United States
Maria Claudia
The price is ￥14,436
￥16,022 total
includes taxes & fees
Dec 21 - Dec 22
Best Western Plus Clemson Hotel & Conference Center
Coffee service
Comfort Suites Anderson-Clemson

Comfort Suites Anderson-Clemson

Comfort Suites Anderson-Clemson
2.5 star property
Anderson
8.4 out of 10, Very Good, (1002)
Surrounded by dining, shopping, and entertainment options, this hotel offers a peaceful atmosphere for restful sleep. The 24-hour fitness center, indoor pool, and helpful staff create a comfortable experience near Anderson Civic Center.
"Clean, comfortable "
United States
Cheryl
The price is ￥16,687
￥18,524 total
includes taxes & fees
Dec 21 - Dec 22
Comfort Suites Anderson-Clemson
Meeting facility
The Abernathy of Clemson

The Abernathy of Clemson

The Abernathy of Clemson
4.0 star property
Clemson
9.6 out of 10, Exceptional, (557)
Located within a 15-minute drive of Clemson University and Lake Keowee, this hotel offers convenient amenities including free WiFi and parking. Enjoy drinks at the bar or meals at the onsite restaurant while staying near Sloan Tennis Center and Littlejohn Coliseum.
"location is amazing! "
United States
colleen
The Abernathy of Clemson
Balcony
Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
2.5 star property
Seneca
9.4 out of 10, Exceptional, (204)
Enjoy a rejuvenating stay at this Seneca hotel with an outdoor pool and fitness center. Just 10 minutes from Clemson University and a short drive to Lake Keowee and Lake Hartwell. Start each morning with complimentary breakfast before exploring nearby Golden Corner Plaza.
"Nice hotel by the lake"
United States
Mike
The price is ￥17,918
￥19,710 total
includes taxes & fees
Dec 21 - Dec 22
Fairfield Inn & Suites Seneca Clemson Univ Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Stay near popular Six Mile attractions

Keowee Springs Golf Course

Enjoy a round of golf in Six Mile at Keowee Springs Golf Course.
See properties

Mile Creek Park

Explore the great outdoors at Mile Creek Park, a lovely green space in Six Mile.
See properties

Learn more about Six Mile

Lake Keowee offers pristine waters for boating, fishing, and swimming with several public access points around Six Mile. Hikers can explore nearby Table Rock State Park's trails leading to spectacular mountain views and refreshing waterfalls.

See all hotels in Six Mile
Lake Keowee is a man–made reservoir in the United States in the state of South Carolina. It was created to serve the needs of a power utility as well as public recreational purposes. One of my favorite places to go in the summer. The water really is that color.
Photo by Deidree DeHart
Open Photo by Deidree DeHart

Top Six Mile Hotel Reviews

The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

10/10 Excellent
"This hotel is wonderful and the location is perfect! "
Allison 1-night trip
Posted 5 days ago
The Shepherd Hotel Downtown Clemson

More cheap stays in Six Mile

Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson

1007 George Smith Mill Rd Anderson SC
The price is ￥9,800 per night from Dec 17 to Dec 18
￥9,800
￥10,878 total
Dec 17 - Dec 18
includes taxes & fees
7.6/10 Good! (1,004 reviews)

Frequently asked questions

Where is the best place to stay in Six Mile?
Days Inn by Wyndham Anderson, located 17.6 mi (28.3 km) from the heart of Six Mile, is a top choice for your stay based on our traveler data. Other good options for your visit to the area are Best Western Plus Clemson Hotel & Conference Center and The Shepherd Hotel Downtown Clemson. See all available top hotels, or vacation rentals in Six Mile.
What are some of the best vacation rentals that Six Mile has to offer?
6 Bedrooms and 3 docks on a Lake Hartwell cove, 3 miles from Clemson by water.: You might want to consider this vacation home rental near Six Mile, which is located on a lake and has a fireplace, a balcony, and a barbecue grill to put you at ease in your new surroundings. It has 6 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and a selection of games. See all vacation rentals in Six Mile.
If I need to cancel my hotel reservation in Six Mile, will I receive a refund?
Yes, the majority of hotel room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, you may still be able to cancel and be given a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Six Mile.
Where can I learn more about changing or cancelling my trip to Six Mile?
To find more details about changing or cancelling your trip to Six Mile, go to https://www.expedia.com/service/.
What are some hotels with pools in Six Mile?
Days Inn by Wyndham Anderson: Offers daily, a seasonal outdoor pool, and free self parking. Best Western Plus Clemson Hotel & Conference Center and Baymont by Wyndham Easley/Greenville are two additional hotels that feature an onsite pool. View all hotels with pools in Six Mile.
What's it like to stay in Six Mile?
Travelers to Six Mile will find plenty to explore and enjoy. In Six Mile, there are 70 hotels and other accommodations to choose from. Find out more about Six Mile.
What is there to see in Six Mile?
Favorite places to visit include Lake Keowee, Keowee Springs Golf Course, and Mile Creek Park. You'll also find Keowee Key Golf Course and Littlejohn Coliseum in the area. Check out what more to see and do in Expedia's Six Mile guide.
What's the weather like in Six Mile?
The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 46°F. Average annual precipitation for Six Mile is 61 inches.

Explore a world of travel with Expedia