Find hotels in Seneca, SC from ￥9,898

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Nov 18 - Nov 19
Tomorrow
Nov 19 - Nov 20
This weekend
Nov 21 - Nov 23
Next weekend
Nov 28 - Nov 30

Filter by

Guest rating
Guest rating
Star rating

Compare 1,627 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Aerial view
Lakeside Lodge Clemson

Lakeside Lodge Clemson

2.5 star property
Seneca
9.0 out of 10, Wonderful, (1003)
"Overall great stay."
United States
Daniel
The price is ￥16,846
￥20,913 total
includes taxes & fees
Dec 15 - Dec 16
Lakeside Lodge Clemson
Exterior
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

2.0 star property
Seneca
9.8 out of 10, Exceptional, (46)
"The place was absolutely magnificent."
United States
David
The price is ￥13,755
￥21,932 total
includes taxes & fees
Dec 15 - Dec 16
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Lobby
Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson

2.5 star property
Seneca
9.2 out of 10, Wonderful, (781)
"Clean room, staff was great, will always stay at this hotel in Clemson. Best place to stay!"
United States
Gretchen
The price is ￥14,782
￥16,260 total
includes taxes & fees
Dec 12 - Dec 13
Tru by Hilton Seneca Clemson
Room, 1 King Bed, Non Smoking | Desk, free cribs/infant beds, rollaway beds, free WiFi
Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area

2.0 star property
Seneca
6.8 out of 10, (714)
"The rooms have been renovated it was nice and clean especially for the price. "
United States
Sherri
The price is ￥11,614
￥12,776 total
includes taxes & fees
Nov 24 - Nov 25
Days Inn by Wyndham Seneca / Clemson Area
Free daily on-the-go breakfast
Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123

2.5 star property
Downtown
8.0 out of 10, Very Good, (659)
"Friendly check in, clean room."
United States
connie
The price is ￥11,738
￥13,845 total
includes taxes & fees
Dec 7 - Dec 8
Quality Inn Seneca Clemson Area US-123
Exterior
Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area

2.5 star property
Seneca
9.2 out of 10, Wonderful, (655)
"Great place to stay"
United States
Jose
The price is ￥16,024
￥17,629 total
includes taxes & fees
Nov 30 - Dec 1
Hampton Inn & Suites Seneca-Clemson Area
Balcony
Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area

2.5 star property
Seneca
9.4 out of 10, Exceptional, (204)
"Nice hotel by the lake"
United States
Mike
The price is ￥18,632
￥20,497 total
includes taxes & fees
Nov 23 - Nov 24
Fairfield Inn & Suites Seneca Clemson Univ Area
Lobby
Best Western Seneca-Clemson

Best Western Seneca-Clemson

2.5 star property
Seneca
8.4 out of 10, Very Good, (632)
"Convenient for Clemson visits."
United States
Kathleen
The price is ￥14,519
￥15,972 total
includes taxes & fees
Nov 25 - Nov 26
Best Western Seneca-Clemson
Lobby
Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area

2.5 star property
Clemson
8.2 out of 10, Very Good, (1003)
"Great stay "
United States
Linda
The price is ￥15,046
￥16,702 total
includes taxes & fees
Nov 24 - Nov 25
Comfort Inn & Suites Clemson - University Area
Free daily continental breakfast
Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson

2.0 star property
Anderson
7.8 out of 10, Good, (1008)
"Rooms were clean, the property was well kept, complimentary breakfast and location is close to everything. "
United States
Kayla
The price is ￥9,721
￥10,790 total
includes taxes & fees
Dec 15 - Dec 16
Days Inn by Wyndham Anderson
Outdoor pool
Baymont by Wyndham Anderson Clemson

Baymont by Wyndham Anderson Clemson

2.5 star property
Anderson
7.0 out of 10, Good, (831)
"Clean attractive room and friendly staff. "
Canada
Lisa
The price is ￥9,239
￥10,256 total
includes taxes & fees
Dec 1 - Dec 2
Baymont by Wyndham Anderson Clemson
Property amenity
Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

2.5 star property
Clemson
8.2 out of 10, Very Good, (1006)
" Clean room, breakfast, staff very nice."
United States
Maria Claudia
The price is ￥14,386
￥15,969 total
includes taxes & fees
Nov 23 - Nov 24
Best Western Plus Clemson Hotel & Conference Center
Reception
Quality Inn Clemson near University

Quality Inn Clemson near University

2.5 star property
Anderson
7.0 out of 10, Good, (886)
"Bueno was "
Mexico
Alejandro
The price is ￥8,916
￥9,898 total
includes taxes & fees
Dec 9 - Dec 10
Quality Inn Clemson near University
Lobby
Baymont by Wyndham Easley/Greenville

Baymont by Wyndham Easley/Greenville

2.5 star property
Easley
7.4 out of 10, Good, (734)
"room was sufficient for my stay. easy check in and out"
United States
Thomas
The price is ￥11,296
￥12,540 total
includes taxes & fees
Nov 19 - Nov 20
Baymont by Wyndham Easley/Greenville
Exterior
Woodspring Suites Anderson North I-85

Woodspring Suites Anderson North I-85

2.5 star property
Anderson
7.4 out of 10, Good, (54)
"Room was wonderful. Employees were on point "
United States
Daniel
The price is ￥13,404
￥14,879 total
includes taxes & fees
Nov 19 - Nov 20
Woodspring Suites Anderson North I-85
Reception
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

2.5 star property
Anderson
9.0 out of 10, Wonderful, (578)
"It was great. Room was clean and staff was friendly. "
United States
Veronica
The price is ￥15,993
￥17,753 total
includes taxes & fees
Nov 23 - Nov 24
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
Lobby
Microtel Inn & Suites by Wyndham Anderson/Clemson

Microtel Inn & Suites by Wyndham Anderson/Clemson

2.0 star property
Anderson
8.2 out of 10, Very Good, (1002)
"Room was clean, staff was nice! "
United States
Martina
The price is ￥12,406
￥13,771 total
includes taxes & fees
Nov 23 - Nov 24
Microtel Inn & Suites by Wyndham Anderson/Clemson
Superior Room, 2 Queen Beds | In-room safe, blackout drapes, soundproofing, iron/ironing board
The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

4.0 star property
Clemson
9.8 out of 10, Exceptional, (727)
"Wonderful staff, great location"
United States
Shelly
The price is ￥26,119
￥28,992 total
includes taxes & fees
Dec 15 - Dec 16
The Shepherd Hotel Downtown Clemson
Exterior
Hilton Garden Inn Anderson

Hilton Garden Inn Anderson

3.0 star property
Anderson
9.0 out of 10, Wonderful, (665)
"Clean Room "
United States
Cynthia
The price is ￥15,950
￥17,704 total
includes taxes & fees
Dec 15 - Dec 16
Hilton Garden Inn Anderson
Lobby lounge
Inn @ Clemson

Inn @ Clemson

2.5 star property
Clemson
8.0 out of 10, Very Good, (1004)
"Very nice staff and great place to stay"
United States
Kimberley
Inn @ Clemson
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Check out family-friendly hotels in Seneca

Balcony
Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area

2.5 star property
Seneca
9.4 out of 10, Exceptional, (204)
The price is ￥18,632
￥20,497 total
includes taxes & fees
Nov 23 - Nov 24
Fairfield Inn & Suites Seneca Clemson Univ Area
View all properties

Hotels with free breakfast in Seneca you'll enjoy

Lobby
Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson

2.5 star property
Seneca
9.2 out of 10, Wonderful, (781)
The price is ￥14,782
￥16,260 total
includes taxes & fees
Dec 12 - Dec 13
Tru by Hilton Seneca Clemson
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Seneca

Find the best Seneca areas and neighborhoods for the activities you enjoy most.

Downtown

While visiting Downtown, you might make a stop by sights like Seneca Historic District and Oconee County Library Seneca Branch.

Pine Ridge Point

While Pine Ridge Point isn't home to many top sights, Lake Keowee and World of Energy are some notable places to visit nearby.

Serenity Bay

Though Serenity Bay might not have many top sights, you can venture to the surrounding area to see attractions like Keowee Key Golf Course and Lake Keowee.

Indian Oaks

While there might not be top attractions in Indian Oaks, you can explore the larger area and discover places like The Gauntlet and Seneca Historic District.

Keowee Plantation

When in Keowee Plantation, you can plan a visit to The Gauntlet and Seneca Historic District, some noteworthy sights in the nearby area.

Stay near popular Seneca attractions

Blue Ridge Field

Blue Ridge Field is just one of the places to see in Seneca, so why not enjoy the other things to explore during your travels? Amble around this family-friendly area's lakeside or attend a sporting event.
See properties

World of Energy

You can spend an afternoon exploring the galleries in World of Energy in Seneca. Amble around this family-friendly area's lakeside or attend a sporting event.
See properties

Learn more about Seneca

Nestled along Lake Keowee's shoreline, this charming town offers spectacular waterfront activities from kayaking to fishing at South Cove County Park. Nearby Stumphouse Tunnel and Issaqueena Falls provide fascinating historical exploration and refreshing natural beauty, especially during summer's humid afternoons.

See all hotels in Seneca
Lake Keowee South Carolina

Top Seneca Hotel Reviews

Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson

10/10 Excellent
"Everytime I book a room with Days Inn I alway walk into a good smelling clean room. Any problems that I might have if I ever do they don’t hesitate to fix the problem right away. They serve a free breakfast every morning from 6am to 9am that’s very good. Sam and his staff are great when it comes to good customer service as well… they treat you like family all the time. "
Aniya 1-night trip
Posted 6 days ago
Days Inn by Wyndham Anderson

More cheap stays in Seneca

Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson

1007 George Smith Mill Rd Anderson SC
The price is ￥9,721 per night from Dec 15 to Dec 16
￥9,721
￥10,790 total
Dec 15 - Dec 16
includes taxes & fees
7.6/10 Good! (1,002 reviews)

Frequently asked questions

Where is the best place for a stay in Seneca?
Lakeside Lodge Clemson is ranked highly by Expedia customers. This hotel offers a restaurant and free parking. Traveler reviews also recommend Fairfield Inn & Suites Seneca Clemson Univ Area and Best Western Seneca-Clemson as top choices for your visit. See all available top hotels, or vacation rentals in Seneca.
What's the top vacation rental in Seneca?
6 Bedrooms and 3 docks on a Lake Hartwell cove, 3 miles from Clemson by water.: Visitors give good reviews to this Seneca vacation home rental, which is located on a lake and has a fireplace, a balcony, and a barbecue grill to put you at ease in your new surroundings. It has 6 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and a selection of games. Some other homes for rent in Seneca include Lake House with Dock, Pool, and Pet Friendly. 8 Minutes from Clemson. and Luxury 4BR/4BA Lake Keowee Retreat- Mountain Cabin Vibes + Private Dock. See all vacation rentals in Seneca.
If I need to cancel my hotel reservation in Seneca, will I receive a refund?
Yes, the majority of hotel reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Seneca.
Where can I learn more about changing or cancelling my trip to Seneca?
To find more details about updating your trip to Seneca or cancelling it, click here.
What's the best place to stay for a family vacation to Seneca?
Fairfield Inn & Suites Seneca Clemson Univ Area is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Attractions in the area like Ultimate Action Sports are also fun for the whole family. Find more child-friendly accommodations in Seneca.
What's the best LGBTQ-friendly place to stay in Seneca?
Hampton Inn & Suites Seneca-Clemson Area is a top LGBTQ-friendly hotel that features free breakfast and free WiFi. Tru by Hilton Seneca Clemson is another good choice for your stay. See all available hotels listed as LGBTQ-friendly in Seneca.
What's the best pet-friendly accommodation in Seneca?
Quality Inn Seneca Clemson Area US-123 is a top hotel for people traveling with their pets, and offers a seasonal outdoor pool and free WiFi for its human guests. Other good choices to stay with your pet include Lakeside Lodge Clemson and Days Inn by Wyndham Seneca / Clemson Area. See more pet-friendly hotel accommodations in Seneca.
What are some hotels with pools in Seneca?
Quality Inn Seneca Clemson Area US-123: Features daily, a seasonal outdoor pool, and free self parking. Lakeside Lodge Clemson and Days Inn by Wyndham Seneca / Clemson Area are two additional hotels with an onsite pool. View all hotels with pools in Seneca.
What is the best accommodation for staying close to Greenville-Spartanburg International Airport (GSP)?
Wyndham Garden Greenville Airport is one of the top choices for your stay and is a popular 3-star hotel featuring free breakfast and a restaurant. It's located 3.8 mi (6.1 km) from Greenville-Spartanburg Intl. Airport. Other good options near the airport include Best Western Greenville Airport Inn and Extended Stay America - Greenville - Airport.
What is staying in Seneca like?
Visitors to Seneca are sure to enjoy the sporting events, lakeside setting, and university setting. Welcoming and scenic, this city also attracts tourists with its coffeehouses. In Seneca, there are 290 hotels and other accommodations to choose from. Find out more about Seneca.
What should I do while I'm visiting Seneca?
Cultural venues include The Gauntlet and Oconee Community Theatre. Natural beauty is on display at Lake Keowee, Lake Hartwell, and Keowee Reservoir. Exploring the waterfront is a great activity, and Keowee Key Golf Course is one place to visit. Check out what more to see and do in Expedia's Seneca guide.
What's the weather like in Seneca?
The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 46°F. Average annual precipitation for Seneca is 62 inches.

Explore a world of travel with Expedia