Find hotels in Seneca, SC from ¥9,706

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Our top choices for Seneca hotels

Lakeside Lodge Clemson

Lakeside Lodge Clemson
2.5 star property
Seneca
9.0 out of 10, Wonderful, (1,005 reviews)
"Great place to stay. "
United States
Gene
The price is ¥17,020
¥21,129 total
includes taxes & fees
Feb 11 - Feb 12
Lakeside Lodge Clemson

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123
2.5 star property
Downtown
8.0 out of 10, Very Good, (674 reviews)
"Our stay was very nice. Clean room. The outside was clean. "
United States
Gayle
The price is ¥12,160
¥14,326 total
includes taxes & fees
Feb 17 - Feb 18
Quality Inn Seneca Clemson Area US-123

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
Seneca
9.8 out of 10, Exceptional, (58 reviews)
"Excellent stay."
United States
Beonca
The price is ¥10,774
¥18,723 total
includes taxes & fees
Feb 17 - Feb 18
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Best Western Seneca-Clemson

Best Western Seneca-Clemson
2.5 star property
Seneca
8.4 out of 10, Very Good, (647 reviews)
"The stay was amazing "
United States
Tabatha
The price is ¥15,795
¥17,374 total
includes taxes & fees
Mar 8 - Mar 9
Best Western Seneca-Clemson

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
2.5 star property
Seneca
9.2 out of 10, Wonderful, (677 reviews)
"Everything was excellent "
United States
Debby
The price is ¥19,107
¥21,020 total
includes taxes & fees
Mar 1 - Mar 2
Hampton Inn & Suites Seneca-Clemson Area

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
2.5 star property
Seneca
9.4 out of 10, Exceptional, (206 reviews)
"Spotless, friendly staff, great location. "
United States
Cari
The price is ¥19,519
¥21,472 total
includes taxes & fees
Feb 15 - Feb 16
Fairfield Inn & Suites Seneca Clemson Univ Area

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
2.5 star property
Seneca
9.2 out of 10, Wonderful, (807 reviews)
"Perfect stay for a weekend. Lots of shopping and restaurants nearby. Clean safe area annd the staff was wonderful!"
United States
Cindy
The price is ¥17,158
¥18,874 total
includes taxes & fees
Feb 17 - Feb 18
Tru by Hilton Seneca Clemson

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
2.0 star property
Seneca
6.8 out of 10, (725 reviews)
"Room was clean. Quiet place to rest. Lisa at the front desk was very helpful and very nice. "
United States
Teresa
The price is ¥11,149
¥12,264 total
includes taxes & fees
Feb 22 - Feb 23
Days Inn by Wyndham Seneca / Clemson Area

Hampton Inn Hartwell

Hampton Inn Hartwell
2.5 star property
Hartwell
9.0 out of 10, Wonderful, (352 reviews)
"Great stay!"
United States
Daniel
The price is ¥13,195
¥15,960 total
includes taxes & fees
Feb 21 - Feb 22
Hampton Inn Hartwell

Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson
2.0 star property
Anderson
7.8 out of 10, Good, (1,006 reviews)
"The room was spotless, the property well kept, the staff was kind and helpful and the location was great! "
United States
Kayla
The price is ¥9,823
¥10,904 total
includes taxes & fees
Feb 15 - Feb 16
Days Inn by Wyndham Anderson

Quality Inn Clemson near University

Quality Inn Clemson near University
2.5 star property
Anderson
7.0 out of 10, Good, (895 reviews)
"Bueno was "
Mexico
Alejandro
The price is ¥7,943
¥8,817 total
includes taxes & fees
Feb 19 - Feb 20
Quality Inn Clemson near University

Baymont by Wyndham Easley/Greenville

Baymont by Wyndham Easley/Greenville
2.5 star property
Easley
7.4 out of 10, Good, (775 reviews)
"Good breakfast friendly staff "
United States
brian
The price is ¥10,119
¥11,232 total
includes taxes & fees
Mar 1 - Mar 2
Baymont by Wyndham Easley/Greenville

Hilton Garden Inn Anderson

Hilton Garden Inn Anderson
3.0 star property
Anderson
9.0 out of 10, Wonderful, (698 reviews)
"Rooms were clean, staff were friendly, and we had 2 good night’s sleep."
United States
Sadie
The price is ¥15,510
¥17,215 total
includes taxes & fees
Feb 19 - Feb 20
Hilton Garden Inn Anderson

Microtel Inn & Suites by Wyndham Anderson/Clemson

Microtel Inn & Suites by Wyndham Anderson/Clemson
2.0 star property
Anderson
8.2 out of 10, Very Good, (1,002 reviews)
"Room was clean, front desk people were very nice. "
United States
Caressa
The price is ¥11,813
¥13,112 total
includes taxes & fees
Feb 12 - Feb 13
Microtel Inn & Suites by Wyndham Anderson/Clemson

Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
2.5 star property
Clemson
8.2 out of 10, Very Good, (1,004 reviews)
"Our room was very clean and the staff were very nice and courteous!"
United States
Tina
The price is ¥15,132
¥16,799 total
includes taxes & fees
Feb 12 - Feb 13
Best Western Plus Clemson Hotel & Conference Center

Rodeway Inn & Suites Walhalla

Rodeway Inn & Suites Walhalla
2.0 star property
Walhalla
7.6 out of 10, Good, (175 reviews)
"Older hotel with great staff. It was safe and provided a great place for a stop over on the way to TN. I would definitely stay here again. "
United States
Laura
The price is ¥10,617
¥11,838 total
includes taxes & fees
Mar 12 - Mar 13
Rodeway Inn & Suites Walhalla

Hampton Inn Anderson/ Alliance Business Park

Hampton Inn Anderson/ Alliance Business Park
2.5 star property
Anderson
9.2 out of 10, Wonderful, (821 reviews)
"Staff, Just a Nice Hotel"
United States
Christopher
The price is ¥17,726
¥19,675 total
includes taxes & fees
Feb 20 - Feb 21
Hampton Inn Anderson/ Alliance Business Park

Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
2.5 star property
Clemson
8.2 out of 10, Very Good, (1,002 reviews)
"Room was extremely clean, continental breakfast was amazing with many options, and staff were very friendly. Great hotel! "
United States
Delaney
The price is ¥15,795
¥17,533 total
includes taxes & fees
Feb 17 - Feb 18
Comfort Inn & Suites Clemson - University Area

Country Inn & Suites by Radisson, Anderson, SC

Country Inn & Suites by Radisson, Anderson, SC
2.5 star property
Anderson
8.4 out of 10, Very Good, (1,000 reviews)
"Everything was clean and breakfast was a nice spread. "
United States
Sheri
The price is ¥17,122
¥19,005 total
includes taxes & fees
Mar 8 - Mar 9
Country Inn & Suites by Radisson, Anderson, SC

Comfort Suites Anderson-Clemson

Comfort Suites Anderson-Clemson
2.5 star property
Anderson
8.4 out of 10, Very Good, (1,002 reviews)
"Everything was Great very friendly people "
United States
jose
The price is ¥17,426
¥19,343 total
includes taxes & fees
Feb 15 - Feb 16
Comfort Suites Anderson-Clemson
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Seneca

Find the best Seneca areas and neighborhoods for the activities you enjoy most.

Downtown

Downtown Seneca captures the essence of small-town Southern charm with its well-preserved railroad heritage and historic brick buildings. Tree-lined streets lead to charming shops and local eateries housed in structures dating back to the 1800s. Ram Cat Alley's colorful murals tell stories of local history while the old courthouse square hosts community gatherings. This walkable district offers a peaceful retreat from big city life. Visitors can browse antique stores for railroad memorabilia, sample authentic Southern comfort food, or explore the cultural exhibits at the Bertha Lee Strickland Museum. The nearby Lake Keowee provides outdoor recreation just minutes away.

Serenity Bay

Serenity Bay offers a peaceful retreat within Saxony Forest's coastal embrace. The quiet residential streets wind through mature trees, creating a tranquil atmosphere away from tourist crowds. Nature lovers can explore nearby Lake Keowee or enjoy the neighborhood's forest trails. The area perfectly balances woodland serenity with beach proximity. Visitors should plan for self-contained vacation rentals rather than hotels. While dining options are limited within the neighborhood, the natural surroundings provide ideal conditions for relaxation and outdoor recreation.

Pine Ridge Point

Lake Keowee's serene waters lap against the shores of Pine Ridge Point, a tranquil residential haven in Seneca. Private docks stretch into crystal-clear waters where boats gently bob. Towering pines create natural privacy between lakefront homes. Visitors enjoy peaceful mornings watching mist rise over the water. This neighborhood offers an authentic lakeside living experience without tourist crowds. Vacation rentals range from cozy cabins to luxury estates with private boat slips. Days revolve around swimming, fishing, and water sports on Lake Keowee. Nature trails wind through mature forests for hiking and birdwatching.

Indian Oaks

Indian Oaks offers a tranquil retreat in suburban Seneca where mature oak trees create natural canopies over peaceful residential streets. This family-oriented community provides an authentic glimpse into American suburban living without tourist crowds. Landscaped yards and community green spaces showcase South Carolina's native beauty. Visitors can enjoy quiet morning walks on spacious sidewalks while listening to birdsong. Lake Keowee lies just beyond the neighborhood boundaries for those seeking water activities. With minimal commercial presence, Indian Oaks delivers a genuinely restful experience away from urban bustle.

Stay near popular Seneca attractions

Learn more about Seneca

Nestled along Lake Keowee's shoreline, this charming town offers spectacular waterfront activities from kayaking to fishing at South Cove County Park. Nearby Stumphouse Tunnel and Issaqueena Falls provide fascinating historical exploration and refreshing natural beauty, especially during summer's humid afternoons.

Lake Keowee South Carolina

Top Seneca Hotel Reviews

More cheap stays in Seneca

Frequently asked questions

Where is the best place for a stay in Seneca?
Tru by Hilton Seneca Clemson is ranked highly by Expedia customers. This hotel offers free breakfast and free parking. Traveler reviews also recommend Lakeside Lodge Clemson and Hampton Inn & Suites Seneca-Clemson Area as top choices for your visit. See all available top hotels, or vacation rentals in Seneca.
What's the top vacation rental in Seneca?
Quiet cove, deep water, minutes to Clemson, pet friendly, easy path to the dock: Visitors give good reviews to this Seneca vacation home rental, which is located on a lake and has a patio, a private yard, and a barbecue grill to put you at ease in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a selection of games. Some other homes for rent in Seneca include Beautiful waterfront home on a private cove in Lake Keowee w/ hot tub and Lake House with Dock, Pool, and Pet Friendly. 8 Minutes from Clemson.. See all vacation rentals in Seneca.
If I need to cancel my hotel reservation in Seneca, will I receive a refund?
Yes, the majority of hotel reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Seneca.
Where can I learn more about changing or cancelling my trip to Seneca?
To find more details about updating your trip to Seneca or cancelling it, click here.
What's the best place to stay for a family vacation to Seneca?
Fairfield Inn & Suites Seneca Clemson Univ Area is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Attractions in the area like Ultimate Action Sports are also fun for the whole family. Find more child-friendly accommodations in Seneca.
What's the best LGBTQ-friendly place to stay in Seneca?
Hampton Inn & Suites Seneca-Clemson Area is a top LGBTQ-friendly hotel that features free breakfast and free WiFi. Tru by Hilton Seneca Clemson is another good choice for your stay. See all available hotels listed as LGBTQ-friendly in Seneca.
What's the best pet-friendly accommodation in Seneca?
Lakeside Lodge Clemson is a top hotel for people traveling with their pets, and offers a restaurant and a seasonal outdoor pool for its human guests. Other good choices to stay with your pet include Days Inn by Wyndham Seneca / Clemson Area and Tru by Hilton Seneca Clemson. See more pet-friendly hotel accommodations in Seneca.
What are some hotels with pools in Seneca?
Lakeside Lodge Clemson: Hotel located near Clemson University. Features free self parking, a seasonal outdoor pool, and complimentary wireless internet access. Quality Inn Seneca Clemson Area US-123 and Hampton Inn & Suites Seneca-Clemson Area are two additional hotels with an onsite pool. View all hotels with pools in Seneca.
What is the best accommodation for staying close to Greenville-Spartanburg International Airport (GSP)?
Wyndham Garden Greenville Airport is one of the top choices for your stay and is a popular 3-star hotel featuring free breakfast and a restaurant. It's located 3.8 mi (6.1 km) from Greenville-Spartanburg Intl. Airport. Other good options near the airport include Best Western Greenville Airport Inn and Extended Stay America - Greenville - Airport.
What is staying in Seneca like?
Visitors to Seneca are sure to enjoy the sporting events, lakeside setting, and university setting. Welcoming and scenic, this city also attracts tourists with its coffeehouses. In Seneca, there are 294 hotels and other accommodations to choose from. Find out more about Seneca.
What should I do while I'm visiting Seneca?
Cultural venues include The Gauntlet and Oconee Community Theatre. Natural beauty is on display at Keowee Reservoir, Lake Keowee, and Lake Hartwell. Exploring the waterfront is a great activity, and Keowee Key Golf Course is one place to visit. Check out what more to see and do in Expedia's Seneca guide.
What's the weather like in Seneca?
The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 46°F. Average annual precipitation for Seneca is 62 inches.

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