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Check prices for these dates

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Jan 18 - Jan 19
Tomorrow
Jan 19 - Jan 20
Next weekend
Jan 23 - Jan 25
In two weeks
Jan 30 - Feb 1

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Our top choices for Santa Lucia hotels

Rooftop terrace

Caportigia Boutique Hotel

Caportigia Boutique Hotel
5.0 star property
Santa Lucia
9.4 out of 10, Exceptional, (258 reviews)
"Fine quality hotel with exceptional service. "
United States
Peter
The price is ￥16,024
￥19,460 total
includes taxes & fees
Jan 27 - Jan 28
Caportigia Boutique Hotel
Aerial view

Grande Albergo Alfeo

Grande Albergo Alfeo
4.0 star property
Santa Lucia
8.6 out of 10, Excellent, (652 reviews)
"The room was nice the location convenient. No view to speak of but centrally located"
Canada
Eric
The price is ￥13,754
￥15,680 total
includes taxes & fees
Jan 19 - Jan 20
Grande Albergo Alfeo
Classic Room | View from room

Gymnasium

Gymnasium
3.0 star property
Santa Lucia
8.8 out of 10, Excellent, (40 reviews)
"Nice kitchen area, centrally located."
United States
Richard
The price is ￥10,513
￥11,984 total
includes taxes & fees
Jan 19 - Jan 20
Gymnasium
Suite, Balcony, Sea View | Minibar, in-room safe, desk, soundproofing

Lakkios

Lakkios
3.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (63 reviews)
"Nice, central, clean, easy to park, quiet during the night, staff was welcoming, nice breakfast with view - excellent choice!"
Norway
Jon-Kåre
The price is ￥14,856
￥16,935 total
includes taxes & fees
Jan 19 - Jan 20
Lakkios
Porch

Piccolo Hotel Casa Mia

Piccolo Hotel Casa Mia
3.0 star property
Santa Lucia
8.6 out of 10, Excellent, (374 reviews)
"The staff is extremely nice and friendly and you feel welcome. "
Canada
Florentina
Piccolo Hotel Casa Mia
Coffee/tea maker, electric kettle

Nostos rooms & Apartments

Nostos rooms & Apartments
3.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (274 reviews)
"Welcoming, room, staff and area around definitely stood out!"
Canada
Aina
The price is ￥9,303
￥10,605 total
includes taxes & fees
Feb 3 - Feb 4
Nostos rooms & Apartments
Breakfast area

Giuggiulena Villa

Giuggiulena Villa
3.0 star property
Santa Lucia
10.0 out of 10, Exceptional, (126 reviews)
"Fantastic stay. Made to feel very welcome and what a lovely relaxing place to stay. Evening meal was exceptional. "
United States
Paul
The price is ￥37,886
￥43,190 total
includes taxes & fees
Jan 24 - Jan 25
Giuggiulena Villa
1 bedroom, down comforters, minibar, in-room safe

Re Dionisio Luxury Suites

Re Dionisio Luxury Suites
3.0 star property
Santa Lucia
8.8 out of 10, Excellent, (57 reviews)
"Spacious room, dated but comfortable."
United States
Kenneth
The price is ￥51,350
￥58,319 total
includes taxes & fees
Feb 10 - Feb 11
Re Dionisio Luxury Suites
View from room

Calafatari B&B

Calafatari B&B
3.0 star property
Santa Lucia
10.0 out of 10, Exceptional, (11 reviews)
"We had a lovely stay. Anna was very welcoming. We had a lovely large clean room and a nice modern bathroom. She went all out for breakfast. "
United States
Carl and Lina
Calafatari B&B
Triple Room, Balcony | Balcony

B&B Nike

B&B Nike
Santa Lucia
8.8 out of 10, Excellent, (75 reviews)
"Clean, good location. "
United States
Salvatore
The price is ￥15,560
￥17,738 total
includes taxes & fees
Feb 17 - Feb 18
B&B Nike
Exclusive Room | In-room safe, soundproofing, iron/ironing board, free WiFi

Isonzo Suites

Isonzo Suites
Santa Lucia
8.4 out of 10, Very Good, (5 reviews)
"."
Italy
Gianluca
The price is ￥10,122
￥16,975 total
includes taxes & fees
Jan 25 - Jan 26
Isonzo Suites
Suite | Soundproofing, free WiFi

Hotel Palazzo Cavalieri

Hotel Palazzo Cavalieri
4.0 star property
Santa Lucia
8.8 out of 10, Excellent, (39 reviews)
"Enjoyed our stay, nice comfortable room and bed. Very nice breakfast buffet. Within a quick 5 min walk to Ortigia Island, also walkable to train and bus station. Would stay here again."
United States
Jennifer
The price is ￥14,005
￥15,964 total
includes taxes & fees
Jan 19 - Jan 20
Hotel Palazzo Cavalieri
Double Room | Premium bedding, desk, cribs/infant beds, rollaway beds

B&B Siracusa

B&B Siracusa
Santa Lucia
9.0 out of 10, Wonderful, (59 reviews)
"Good location, very modern clean accommodation."
Canada
Malcolm
The price is ￥13,497
￥15,386 total
includes taxes & fees
Jan 19 - Jan 20
B&B Siracusa
Exterior

AmaCasa Siracusa

AmaCasa Siracusa
Santa Lucia
10.0 out of 10, Exceptional, (1 review)
"Siamo stati molto bene, la struttura internamente è abbastanza ammodernata e l'accesso è stato"
Italy
Alessandro
The price is ￥14,006
￥15,965 total
includes taxes & fees
Jan 19 - Jan 20
AmaCasa Siracusa
Lobby lounge

Regina Margherita

Regina Margherita
Santa Lucia
8.0 out of 10, Very Good, (14 reviews)
"The area is so close to the Ortigia Island where the beautiful cathedral and Doumo are. Lovely walk around the entire island and areas to go in the water If you like. Many dining options and shopping too. Wonderful area!"
United States
Laura
The price is ￥9,340
￥10,648 total
includes taxes & fees
Jan 25 - Jan 26
Regina Margherita
Free daily buffet breakfast

San Nicola Rooms Siracusa

San Nicola Rooms Siracusa
Santa Lucia
9.4 out of 10, Exceptional, (3 reviews)
"Stanza molto bella e nuova, ottimi arredi, letto comodo e cuscini comodi, belle tende, bagno bello e pulito, specchio del bagno fantastico con una luce bellissima regolabile a led. Mi sono trovato bene, il personale gentilissimo in particolare la ragazza (Lucia se non ricordo male) super cordiale!"
Italy
Davide Angelo
The price is ￥12,604
￥14,368 total
includes taxes & fees
Jan 27 - Jan 28
San Nicola Rooms Siracusa
Exterior

Agorà

Agorà
Santa Lucia
10.0 out of 10, Exceptional, (2 reviews)
"Trevligt, rent, bra service. Hade turen att få balkong. "
Sweden
Olof
The price is ￥14,244
￥16,238 total
includes taxes & fees
Jan 25 - Jan 26
Agorà
Comfort Triple Room, Balcony, Ocean View | View from room

Hotel Mediterraneo

Hotel Mediterraneo
3.0 star property
Santa Lucia
7.8 out of 10, Good, (123 reviews)
"Very friendly and helpful staff."
United States
David
The price is ￥9,266
￥10,562 total
includes taxes & fees
Feb 1 - Feb 2
Hotel Mediterraneo
Exterior

Populus

Populus
1.0 star property
Santa Lucia
7.8 out of 10, Good, (74 reviews)
"Just stay somewhere else, plain and simple."
United States
Thomas
The price is ￥12,426
￥14,166 total
includes taxes & fees
Jan 26 - Jan 27
Populus
Double Room, 1 King Bed, Sea View, Tower | In-room safe, desk, soundproofing, iron/ironing board

Casa Miranda Boutique

Casa Miranda Boutique
Santa Lucia
6.0 out of 10, (1 review)
The price is ￥29,128
￥33,875 total
includes taxes & fees
Jan 26 - Jan 27
Casa Miranda Boutique
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Santa Lucia

Find the best Santa Lucia areas and neighborhoods for the activities you enjoy most.
Temple of Apollo featuring a ruin and heritage elements

Ortigia

Travelers come to Ortigia for its seaside views, and you can see top attractions like Cathedral of Syracuse and Piazza del Duomo while you're in town.

Neapolis

While visiting Neapolis, you might make a stop by sights like Roman Amphitheatre of Syracuse and Archaeological Park of Neapolis.

Tiche

Gardens and restaurants are notable features of Tiche. You might consider a stop by Ionian Sea while you're exploring the neighborhood.

Grottasanta

Grottasanta is noteworthy for its historic sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.

Acradina

You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.

Top Santa Lucia Hotel Reviews

Domus Mariae Albergo

Domus Mariae Albergo

10/10 Excellent
"Beautiful Otigia! Most helpful staff!"
David 1-night trip
Posted 1 day ago
Domus Mariae Albergo

Frequently asked questions

What is Santa Lucia like?
Santa Lucia is a neighborhood that people enjoy for its interesting historical sites. Are you looking for Santa Lucia travel tips? Be sure to check out Porto Piccolo and Ionian Sea while you're in the neighborhood.
Where is the best place to stay in Santa Lucia?
Based on Expedia customer reviews, Caportigia Boutique Hotel is the highest ranked property in Santa Lucia. This property offers a restaurant and free parking. Other top choices in the neighborhood include Lakkios and La casa di Aneupe.
How many hotels can I expect to find in Santa Lucia?
Expedia has 289 hotels and other accommodations in Santa Lucia to choose from, making this an ideal home base for exploring the greater Syracuse area.
If I need to cancel my hotel reservation in Santa Lucia, will I receive a refund?
Yes, you'll find most hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then use the filter option "fully refundable" to get the best options available in Santa Lucia.
Where can I learn more about changing or cancelling my trip to Santa Lucia?
For more details about changing or cancelling your trip to Santa Lucia, click here.
What are the top things to see and do in Santa Lucia?
Landmarks in Santa Lucia that you won't want to miss include Syracuse Forum Ruins and Santa Lucia Bridge. Porto Piccolo and Ionian Sea are some other stops to visit in the neighborhood. A few places to visit in the area around Santa Lucia include Piazza Santa Lucia, Santa Lucia al Sepolcro Basilica, and Madonna delle Lacrime. When you're sightseeing in Syracuse, Papyrus Museum and Museo Archeologico Regionale Paolo Orsi are also worth a stop.

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