A modern building with a unique triangular roof and a central spire.

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Check prices for these dates

This weekend
Jul 17 - Jul 19
Next weekend
Jul 24 - Jul 26

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Our top choices for Santa Lucia hotels

Luxury Quadruple Room, Balcony, City View | In-room safe, desk, soundproofing, iron/ironing board

B&B IL MORO

B&B IL MORO
Santa Lucia
The price is ￥10,963
￥16,707 total
includes taxes & fees
Jul 16 - Jul 17
B&B IL MORO
Comfort Double Room | Soundproofing, free WiFi

Melody rooms

Melody rooms
Santa Lucia
The price is ￥7,155
￥8,157 total
includes taxes & fees
Jul 24 - Jul 25
Melody rooms
Terrace/patio

Le Camere Luxsury Rooms

Le Camere Luxsury Rooms
Santa Lucia
7.0 out of 10, Good, (2 reviews)
"Très belle chambre, mais forte odeur d’humidité, pas de FENÊTRE quartier type « cour des Miracles «  loin du centre historique, pas de supérette ou de restaurant dans le proche voisinage loin de toute commodité"
France
Philippe
The price is ￥9,733
￥15,313 total
includes taxes & fees
Jul 20 - Jul 21
Le Camere Luxsury Rooms
Free WiFi

B&B L'INFIORESCENZA

B&B L'INFIORESCENZA
Santa Lucia
8.0 out of 10, Very Good, (2 reviews)
"Camera pulita cuscini scomodi pareti sottilissime si sente nelle stanze intorno qualsiasi piccolissimo rumore, colazione al bar cappuccino ottimo e paste molto grandi e buone, negozi nelle vicinanze no e distanza da Ortigia 15 minuti a piedi circa."
Italy
Loris
The price is ￥6,736
￥9,787 total
includes taxes & fees
Aug 9 - Aug 10
B&B L'INFIORESCENZA
Coffee/tea maker, electric kettle

Nostos rooms & Apartments

Nostos rooms & Apartments
3.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (282 reviews)
"Room clean, air-conditioning good, beds good, staff nice. Not really sound proof, but everyone is respectful and quiet during the night. Staff isn't always at the reception, but that didn't bother us. Super central, super safe. There's no lifts though."
United Kingdom
Amanda
The price is ￥10,570
￥12,050 total
includes taxes & fees
Jul 17 - Jul 18
Nostos rooms & Apartments
Classic Room | View from room

Gymnasium

Gymnasium
3.0 star property
Santa Lucia
8.8 out of 10, Excellent, (42 reviews)
"Nice kitchen area, centrally located."
United States
Richard
The price is ￥11,326
￥12,911 total
includes taxes & fees
Jul 15 - Jul 16
Gymnasium
Porch

Piccolo Hotel Casa Mia

Piccolo Hotel Casa Mia
3.0 star property
Santa Lucia
8.6 out of 10, Excellent, (386 reviews)
"This was my favorite stay in Sicily! I love the elevator and the staff were really nice and accommodating. I also want to point out the excellent AC inside the room. I would only suggest a bottle of water inside the room and a personal tea/ coffee station."
United States
Diane
The price is ￥12,683
￥14,459 total
includes taxes & fees
Jul 24 - Jul 25
Piccolo Hotel Casa Mia
Double Room | Premium bedding, desk, cribs/infant beds, rollaway beds

B&B Siracusa

B&B Siracusa
Santa Lucia
9.0 out of 10, Wonderful, (60 reviews)
"Good location, very modern clean accommodation."
Canada
Malcolm
The price is ￥11,604
￥13,228 total
includes taxes & fees
Jul 15 - Jul 16
B&B Siracusa
Triple Room, Balcony | Balcony

B&B Nike

B&B Nike
Santa Lucia
9.0 out of 10, Wonderful, (86 reviews)
"Clean, good location. "
United States
Salvatore
The price is ￥13,434
￥15,316 total
includes taxes & fees
Jul 28 - Jul 29
B&B Nike
Exterior

Populus

Populus
1.0 star property
Santa Lucia
7.8 out of 10, Good, (75 reviews)
"Just stay somewhere else, plain and simple."
United States
Thomas
The price is ￥11,749
￥13,395 total
includes taxes & fees
Jul 15 - Jul 16
Populus
Lobby lounge

Regina Margherita

Regina Margherita
Santa Lucia
7.8 out of 10, Good, (17 reviews)
"The area is so close to the Ortigia Island where the beautiful cathedral and Doumo are. Lovely walk around the entire island and areas to go in the water If you like. Many dining options and shopping too. Wonderful area!"
United States
Laura
The price is ￥13,073
￥14,902 total
includes taxes & fees
Jul 26 - Jul 27
Regina Margherita
Comfort Triple Room, Balcony, Ocean View | View from room

Hotel Mediterraneo

Hotel Mediterraneo
3.0 star property
Santa Lucia
7.8 out of 10, Good, (124 reviews)
"Very friendly and helpful staff."
United States
David
The price is ￥14,665
￥16,718 total
includes taxes & fees
Jul 19 - Jul 20
Hotel Mediterraneo
Apartment, Balcony, Partial Sea View | Interior

Eos Serenity Suites

Eos Serenity Suites
Santa Lucia
The price is ￥20,537
￥23,412 total
includes taxes & fees
Jul 19 - Jul 20
Eos Serenity Suites
Superior Double Room | Frette Italian sheets, premium bedding, down comforters, desk

Fortuna Guest House

Fortuna Guest House
1.0 star property
Santa Lucia
9.2 out of 10, Wonderful, (19 reviews)
"The owner was really nice and helpful! Really enjoyed our stay here."
Finland
Kirsi
The price is ￥14,729
￥16,791 total
includes taxes & fees
Jul 15 - Jul 16
Fortuna Guest House
Deluxe Studio, 1 Queen Bed, Kitchen | Outdoor dining

Eos Elegant Apartment & Suites

Eos Elegant Apartment & Suites
Santa Lucia
The price is ￥16,309
￥19,786 total
includes taxes & fees
Jul 15 - Jul 16
Eos Elegant Apartment & Suites
Suite, Balcony, Sea View | Minibar, in-room safe, desk, soundproofing

Lakkios

Lakkios
3.0 star property
Santa Lucia
9.2 out of 10, Wonderful, (74 reviews)
"The room appeared to be recently remodeled and was very modern. Of the 4 hotels that we stayed at on this trip, the bed/pillows were the most comfortable. Great view of the marina from our room balcony and public parking (free) was relatively easy. "
United States
Michael
The price is ￥17,406
￥19,843 total
includes taxes & fees
Jul 21 - Jul 22
Lakkios
Exclusive Room | In-room safe, soundproofing, iron/ironing board, free WiFi

Isonzo Suites

Isonzo Suites
Santa Lucia
8.8 out of 10, Excellent, (6 reviews)
"."
Italy
Gianluca
The price is ￥15,975
￥23,683 total
includes taxes & fees
Aug 2 - Aug 3
Isonzo Suites
Rooftop terrace

Caportigia Boutique Hotel

Caportigia Boutique Hotel
5.0 star property
Santa Lucia
9.4 out of 10, Exceptional, (286 reviews)
"Beautiful hotel with good amenities"
Canada
Alessia
The price is ￥31,880
￥36,914 total
includes taxes & fees
Jul 18 - Jul 19
Caportigia Boutique Hotel
Free daily buffet breakfast

San Nicola Rooms Siracusa

San Nicola Rooms Siracusa
Santa Lucia
9.4 out of 10, Exceptional, (9 reviews)
"The breakfast was great! The hosts were super friendly and helpful!"
United States
Lin
The price is ￥16,687
￥19,024 total
includes taxes & fees
Jul 25 - Jul 26
San Nicola Rooms Siracusa
Front of property

Grande Albergo Alfeo

Grande Albergo Alfeo
4.0 star property
Santa Lucia
8.6 out of 10, Excellent, (683 reviews)
"This accommodation was very comfortable and I would highly recommend it."
Australia
Janet
The price is ￥18,900
￥21,547 total
includes taxes & fees
Jul 16 - Jul 17
Grande Albergo Alfeo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Santa Lucia

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Breakfast area
Giuggiulena Villa
3.0 star property
10.0
Exceptional
129 reviews
View
Rooftop terrace
Caportigia Boutique Hotel
5.0 star property
9.4
Exceptional
286 reviews
View
Suite, Balcony, Sea View | Minibar, in-room safe, desk, soundproofing
Lakkios
3.0 star property
9.2
Wonderful
74 reviews
View
Coffee/tea maker, electric kettle
Nostos rooms & Apartments
3.0 star property
9.0
Wonderful
282 reviews
View
Suite | Soundproofing, free WiFi
Hotel Palazzo Cavalieri
4.0 star property
9.0
Wonderful
43 reviews
View

Where to stay in Santa Lucia

Find the best Santa Lucia areas and neighborhoods for the activities you enjoy most.
A historic waterfront with a stone bridge, illuminated buildings, and a calm water body.

Ortigia

Travelers come to Ortigia for its seaside views, and you can see top attractions like Cathedral of Syracuse and Piazza del Duomo while you're in town.

Ancient ruins with a large amphitheater surrounded by trees.
Photo by William Keller
Open Photo by William Keller

Neapolis

While visiting Neapolis, you might make a stop by sights like Archaeological Park of Neapolis and Greek Theatre of Syracuse.

A natural rock arch over a body of water with people paddling in kayaks.

Grottasanta

Grottasanta is noteworthy for its historic sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.

An ancient amphitheater with stone ruins and a grassy field.

Tiche

Gardens and restaurants are notable features of Tiche. You might consider a stop by Ionian Sea while you're exploring the neighborhood.

Acradina

You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.

Top Santa Lucia Hotel Reviews

Domus Mariae Albergo

Domus Mariae Albergo

10/10 Excellent
"I had to book a new hotel last minute and the single room with balcony was available. As a solo traveller what more do you need? I am honestly very grateful I booked this room. Even though the bathroom is very old and could use a bit of lipstick and the shower was a bit of a chaotic experience I still really enjoyed my stay here. Nothing beats the sound of the ocean in the morning, the beautiful ocean view, and the ocean breeze. Ortigia was my favourite stop on my three week trip. And I have the hotel and staff there to thank for helping out with that."
Chantal 2-night trip
Posted 13 hours ago
Domus Mariae Albergo

Frequently asked questions

What is Santa Lucia like?
Santa Lucia is a neighborhood that people enjoy for its interesting historical sites. Are you looking for Santa Lucia travel tips? Be sure to check out Porto Piccolo and Ionian Sea while you're in the neighborhood.
Where is the best place to stay in Santa Lucia?
Based on our traveler data, Grande Albergo Alfeo is one of the top choices for your stay in Santa Lucia. This hotel is a short 9-minute walk from Lungomare di Ortigia, and it offers free breakfast and a restaurant. Other good choices for your stay in the area include Caportigia Boutique Hotel and Fortaleza Charme House.
How many hotels can I expect to find in Santa Lucia?
Expedia has 312 hotels and other accommodations in Santa Lucia to choose from, making this an ideal home base for exploring the greater Syracuse area.
If I need to cancel my hotel reservation in Santa Lucia, will I receive a refund?
Yes, you'll find most hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then use the filter option "fully refundable" to get the best options available in Santa Lucia.
Where can I learn more about changing or cancelling my trip to Santa Lucia?
For more details about changing or cancelling your trip to Santa Lucia, click here.
What are the top things to see and do in Santa Lucia?
Landmarks in Santa Lucia that you won't want to miss include Syracuse Forum Ruins and Santa Lucia Bridge. Porto Piccolo and Ionian Sea are some other stops to visit in the neighborhood. A few places to visit in the area around Santa Lucia include Piazza Santa Lucia, Santa Lucia al Sepolcro Basilica, and Madonna delle Lacrime. When you're sightseeing in Syracuse, Papyrus Museum and Museo Archeologico Regionale Paolo Orsi are also worth a stop.

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