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Our top choices for Santa Lucia hotels

Caportigia Boutique Hotel

Caportigia Boutique Hotel
5.0 star property
Santa Lucia
9.4 out of 10, Exceptional, (274 reviews)
"Excellent modern property, staff are all amazing. Walkable to everything."
Canada
Brian
The price is ¥32,837
¥37,967 total
includes taxes & fees
May 12 - May 13
Caportigia Boutique Hotel

Calafatari B&B

Calafatari B&B
3.0 star property
Santa Lucia
10.0 out of 10, Exceptional, (11 reviews)
"We had a lovely stay. Anna was very welcoming. We had a lovely large clean room and a nice modern bathroom. She went all out for breakfast. "
United States
Carl and Lina
The price is ¥26,585
¥30,307 total
includes taxes & fees
May 11 - May 12
Calafatari B&B

Fortaleza Charme House

Fortaleza Charme House
Santa Lucia
10.0 out of 10, Exceptional, (31 reviews)
"Great central location."
United States
Craig
The price is ¥28,708
¥32,727 total
includes taxes & fees
May 26 - May 27
Fortaleza Charme House

Nostos rooms & Apartments

Nostos rooms & Apartments
3.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (277 reviews)
"I loved this stay. Was so nice to have a kitchenette. Superb location. Staff was fantastic. Nice private terrace. Climate control worked well. Very quiet inside apartment despite being on a main street. Would absolutely stay again. "
United States
Adam
The price is ¥14,238
¥16,231 total
includes taxes & fees
Jun 7 - Jun 8
Nostos rooms & Apartments

AmaCasa Siracusa

AmaCasa Siracusa
Santa Lucia
10.0 out of 10, Exceptional, (1 review)
"Siamo stati molto bene, la struttura internamente è abbastanza ammodernata e l'accesso è stato"
Italy
Alessandro
The price is ¥13,860
¥15,801 total
includes taxes & fees
May 15 - May 16
AmaCasa Siracusa

Giuggiulena Villa

Giuggiulena Villa
3.0 star property
Santa Lucia
10.0 out of 10, Exceptional, (126 reviews)
"Fantastic stay. Made to feel very welcome and what a lovely relaxing place to stay. Evening meal was exceptional. "
United States
Paul
The price is ¥36,557
¥41,674 total
includes taxes & fees
May 13 - May 14
Giuggiulena Villa

Eos Sea View Apartment

Eos Sea View Apartment
Santa Lucia
The price is ¥33,398
¥43,308 total
includes taxes & fees
Jun 2 - Jun 3
Eos Sea View Apartment

San Nicola Rooms Siracusa

San Nicola Rooms Siracusa
Santa Lucia
9.2 out of 10, Wonderful, (7 reviews)
"Very unique property and very well maintained! Great location and walking distance to Ortigia! Staff was friendly and breakfast was nice."
Canada
Trina
The price is ¥19,162
¥21,845 total
includes taxes & fees
May 8 - May 9
San Nicola Rooms Siracusa

Hotel Palazzo Cavalieri

Hotel Palazzo Cavalieri
4.0 star property
Santa Lucia
8.8 out of 10, Excellent, (41 reviews)
"Staff was very friendly and helpful. Loved that the front desk was open 24/7 and the location and walk ability was perfect. Room was clean and spacious. The bathroom could use some updating but all worked well and we enjoyed the provided shampoos, soaps, lotions, etc. Very impressed by the included breakfast each morning. Lots of options and all was fresh and tasty. "
United States
Tiffany
The price is ¥19,572
¥22,312 total
includes taxes & fees
May 25 - May 26
Hotel Palazzo Cavalieri

Eos Serenity Suites

Eos Serenity Suites
Santa Lucia
The price is ¥21,374
¥24,366 total
includes taxes & fees
May 11 - May 12
Eos Serenity Suites

B&B Nike

B&B Nike
Santa Lucia
9.0 out of 10, Wonderful, (78 reviews)
"An unforgettable night in Siracusa! Excellent location only 10 min from Duomo via one of the 2 bridges. Free parking available as well."
United Kingdom
mariana
The price is ¥11,073
¥12,624 total
includes taxes & fees
May 13 - May 14
B&B Nike

B&B Siracusa

B&B Siracusa
Santa Lucia
9.0 out of 10, Wonderful, (59 reviews)
"Ottima camera, in posizione centrale, bene attrezzata, ricca colazione "
Italy
Marco
The price is ¥13,676
¥15,590 total
includes taxes & fees
May 11 - May 12
B&B Siracusa

Lakkios

Lakkios
3.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (65 reviews)
"Nice, central, clean, easy to park, quiet during the night, staff was welcoming, nice breakfast with view - excellent choice!"
Norway
Jon-Kåre
The price is ¥17,102
¥19,495 total
includes taxes & fees
May 10 - May 11
Lakkios

Grande Albergo Alfeo

Grande Albergo Alfeo
4.0 star property
Santa Lucia
8.6 out of 10, Excellent, (665 reviews)
"Good front desk staff, welcoming breakfast staff, clean room and good area for walking to attractions. "
Canada
Reita
The price is ¥18,035
¥20,561 total
includes taxes & fees
May 17 - May 18
Grande Albergo Alfeo

Re Dionisio Luxury Suites

Re Dionisio Luxury Suites
3.0 star property
Santa Lucia
8.8 out of 10, Excellent, (57 reviews)
"Spacious room, dated but comfortable."
United States
Kenneth
The price is ¥40,955
¥46,887 total
includes taxes & fees
May 11 - May 12
Re Dionisio Luxury Suites

Piccolo Hotel Casa Mia

Piccolo Hotel Casa Mia
3.0 star property
Santa Lucia
8.6 out of 10, Excellent, (379 reviews)
"The staff is extremely nice and friendly and you feel welcome. "
Canada
Florentina
The price is ¥16,054
¥18,303 total
includes taxes & fees
Jun 2 - Jun 3
Piccolo Hotel Casa Mia

Gymnasium

Gymnasium
3.0 star property
Santa Lucia
8.8 out of 10, Excellent, (40 reviews)
"Nice kitchen area, centrally located."
United States
Richard
The price is ¥9,573
¥10,912 total
includes taxes & fees
May 13 - May 14
Gymnasium

Isonzo Suites

Isonzo Suites
Santa Lucia
8.8 out of 10, Excellent, (6 reviews)
"."
Italy
Gianluca
The price is ¥18,563
¥26,633 total
includes taxes & fees
May 28 - May 29
Isonzo Suites

Casa Miranda Boutique

Casa Miranda Boutique
Santa Lucia
6.0 out of 10, (1 review)
The price is ¥45,273
¥51,611 total
includes taxes & fees
May 22 - May 23
Casa Miranda Boutique

Melody rooms

Melody rooms
Santa Lucia
The price is ¥6,980
¥7,957 total
includes taxes & fees
May 13 - May 14
Melody rooms
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Santa Lucia

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Rooftop terrace
Caportigia Boutique Hotel
5.0 star property
9.4
Exceptional
274 reviews
View
Coffee/tea maker, electric kettle
Nostos rooms & Apartments
3.0 star property
9.0
Wonderful
277 reviews
View
Superior Double Room | Frette Italian sheets, premium bedding, down comforters, desk
Fortuna Guest House
1.0 star property
9.2
Wonderful
16 reviews
View
Suite, Balcony, Sea View | Minibar, in-room safe, desk, soundproofing
Lakkios
3.0 star property
9.0
Wonderful
65 reviews
View
Classic Room | View from room
Gymnasium
3.0 star property
8.8
Excellent
40 reviews
View

Where to stay in Santa Lucia

Find the best Santa Lucia areas and neighborhoods for the activities you enjoy most.

Ortigia

Travelers come to Ortigia for its seaside views, and you can see top attractions like Cathedral of Syracuse and Piazza del Duomo while you're in town.

Neapolis

While visiting Neapolis, you might make a stop by sights like Archaeological Park of Neapolis and Greek Theatre of Syracuse.

Acradina

You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.

Grottasanta

Grottasanta is noteworthy for its historic sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.

Tiche

Gardens and restaurants are notable features of Tiche. You might consider a stop by Ionian Sea while you're exploring the neighborhood.

Top Santa Lucia Hotel Reviews

Frequently asked questions

What is Santa Lucia like?
Santa Lucia is a neighborhood that people enjoy for its interesting historical sites. Are you looking for Santa Lucia travel tips? Be sure to check out Porto Piccolo and Ionian Sea while you're in the neighborhood.
Where is the best place to stay in Santa Lucia?
Based on our traveler data, Grande Albergo Alfeo is one of the top choices for your stay in Santa Lucia. This hotel offers free breakfast and a restaurant. Other good choices for your stay in the area include Caportigia Boutique Hotel and Nostos rooms & Apartments.
How many hotels can I expect to find in Santa Lucia?
Expedia has 306 hotels and other accommodations in Santa Lucia to choose from, making this an ideal home base for exploring the greater Syracuse area.
If I need to cancel my hotel reservation in Santa Lucia, will I receive a refund?
Yes, you'll find most hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then use the filter option "fully refundable" to get the best options available in Santa Lucia.
Where can I learn more about changing or cancelling my trip to Santa Lucia?
For more details about changing or cancelling your trip to Santa Lucia, click here.
What are the top things to see and do in Santa Lucia?
Landmarks in Santa Lucia that you won't want to miss include Syracuse Forum Ruins and Santa Lucia Bridge. Porto Piccolo and Ionian Sea are some other stops to visit in the neighborhood. A few places to visit in the area around Santa Lucia include Piazza Santa Lucia, Santa Lucia al Sepolcro Basilica, and Madonna delle Lacrime. When you're sightseeing in Syracuse, Papyrus Museum and Museo Archeologico Regionale Paolo Orsi are also worth a stop.