Santa Isabel Vacation Rentals
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Check prices for these dates
Vacation Rentals in Santa Isabel

Private Over the Water Cabin on San Blas Island
Narganá
7.0 out of 10, Good, (6)

Paradise Over the Water Cabins in San Blas
Narganá
6.0 out of 10, (1)

BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES
Santa Isabel
10.0 out of 10, Exceptional, (30)

Caribbean getaway: beach cottage just on the sand
Palenque
10.0 out of 10, Exceptional, (1)
The price is ¥36,652
¥45,925 total
includes taxes & fees
Nov 18 - Nov 19

Caribbean Paradise - Beachfront Getaway
Palenque
The price is ¥57,956
¥76,038 total
includes taxes & fees
Nov 18 - Nov 19

Catamaran experience in paradise
Guna Yala Comarca
The price is ¥89,802
¥184,633 total
includes taxes & fees
Nov 18 - Nov 19

- SV La Francesca - san blas paradise on bord of private sailboat
San blas, Guna yala

4-bedroom beachfront paradise in Palenque with AC, pool, walking trail and more!
Palenque
The price is ¥104,321
¥124,567 total
includes taxes & fees
Nov 30 - Dec 1
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Top Santa Isabel Hotel Reviews
Caribbean getaway: beach cottage just on the sand
10/10 Excellent
Find out more about Santa Isabel
Search for holiday rentals in Santa Isabel on Expedia! You can easily find your home rentals, villas, holiday apartments in Santa Isabel using one of the methods below:
- View our selection of featured holiday rentals in Santa Isabel
- Use the map to find apartments and other holiday homes in the Santa Isabel neighbourhood you prefer
- Enter your travel dates to view the best deals on holiday rentals in Santa Isabel while they last
Look no further and take a look at our great range of rental properties in Santa Isabel!



































































