Find hotels in Santa Cruz Tlaxcala from ￥2,716

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Our top choices for Santa Cruz Tlaxcala hotels

Exterior
Molino de los Reyes

Molino de los Reyes

Molino de los Reyes
3.5 star property
Totolac
8.8 out of 10, Excellent, (8)
Unwind at this Totolac hotel offering complimentary cooked-to-order breakfast, WiFi, and parking. Explore nearby Xicotencatl National Park or visit Palacio Municipal. The convenient location puts you just 40 minutes from Puebla International Airport.
"El servicio es de lo mejor y el lugar muy bonito"
Mexico
LUZ MARIA
Molino de los Reyes
Exclusive Apartment | In-room safe, free WiFi
Departamento Sasha

Departamento Sasha

Departamento Sasha
2.0 star property
Val'Quirico
The price is ￥27,822
￥38,866 total
includes taxes & fees
Dec 15 - Dec 16
Departamento Sasha
Fountain
Hotel Posada La Casona de Cortes

Hotel Posada La Casona de Cortes

Hotel Posada La Casona de Cortes
3.0 star property
Tlaxcala
8.4 out of 10, Very Good, (198)
Immerse yourself in historic elegance at this colonial retreat near Xicotencatl Theater. Free valet parking, WiFi, and 24-hour assistance complement the peaceful garden and terrace where you can relax after exploring nearby Palacio Municipal attractions.
"Beautiful hotel"
United States
Atilio
The price is ￥6,059
￥7,150 total
includes taxes & fees
Dec 21 - Dec 22
Hotel Posada La Casona de Cortes
Bar (on property)
Hotel San Francisco Tlaxcala

Hotel San Francisco Tlaxcala

Hotel San Francisco Tlaxcala
3.5 star property
Tlaxcala
9.0 out of 10, Wonderful, (370)
This tranquil hotel offers 2 restaurants and an outdoor pool with poolside bar near Art Museum of Tlaxcala. After complimentary breakfast, explore nearby Museo de la Memoria. Guests praise the attentive staff and convenient free WiFi and parking.
"Good Hotel."
United States
Dallas
The price is ￥9,824
￥11,592 total
includes taxes & fees
Dec 23 - Dec 24
Hotel San Francisco Tlaxcala
Interior
Hotel Real Malintzi Tlaxcala

Hotel Real Malintzi Tlaxcala

Hotel Real Malintzi Tlaxcala
2.5 star property
Tlaxcala
7.2 out of 10, Good, (99)
Escape to this tranquil hotel featuring a lovely terrace and garden oasis. Located near Xicotencatl National Park and Palacio Municipal, guests enjoy free WiFi, parking, and 24-hour assistance for a hassle-free stay.
"X"
Mexico
Elvin
The price is ￥4,032
￥4,758 total
includes taxes & fees
Dec 14 - Dec 15
Hotel Real Malintzi Tlaxcala
Land view from property
HOTEL XIADANI temazcal y SPA

HOTEL XIADANI temazcal y SPA

HOTEL XIADANI temazcal y SPA
3.0 star property
Tlaxcala
9.2 out of 10, Wonderful, (51)
Tranquil retreat with soothing massages and a welcoming café near University Cultural Center. Free WiFi and parking enhance your stay while exploring Regional Museum of Tlaxcala and local attractions.
"excelente"
Mexico
Danae
The price is ￥4,136
￥4,880 total
includes taxes & fees
Jan 13 - Jan 14, 2026
HOTEL XIADANI temazcal y SPA
Meeting facility
Holiday Inn Tlaxcala by IHG

Holiday Inn Tlaxcala by IHG

Holiday Inn Tlaxcala by IHG
3.5 star property
Yauhquemehcan
9.6 out of 10, Exceptional, (239)
International dining at Mayana restaurant and a full-service spa offering hot stone massages await at this hotel. Free WiFi, convenient parking, and a fitness center enhance your stay near Basilica of Ocotlan.
"Todo excelente"
Mexico
carlos
The price is ￥14,680
￥17,323 total
includes taxes & fees
Dec 27 - Dec 28
Holiday Inn Tlaxcala by IHG
Rooftop terrace
Capital O Hotel Boutique Las Torres

Capital O Hotel Boutique Las Torres

Capital O Hotel Boutique Las Torres
3.0 star property
Tlaxcala
9.0 out of 10, Wonderful, (64)
Experience comfort in the heart of Tlaxcala, minutes from Art Museum and Museo Vivo de Artes y Tradiciones Populares. This hotel offers free WiFi, 24-hour reception, and daily housekeeping for a hassle-free cultural getaway.
"Safe and great stay. "
United States
Ashley
The price is ￥6,360
￥8,205 total
includes taxes & fees
Dec 14 - Dec 15
Capital O Hotel Boutique Las Torres
Terrace/patio
Hotel Tlaxcala

Hotel Tlaxcala

Hotel Tlaxcala
3.5 star property
Tlaxcala
8.2 out of 10, Very Good, (100)
Unwind in this centrally located hotel with easy access to Xicotencatl National Park and Palacio Municipal. Enjoy a drink at the bar after exploring local attractions, then pamper yourself with in-room massage services. Free WiFi and parking enhance your stay.
"👍"
Mexico
Gerardo
The price is ￥4,966
￥5,860 total
includes taxes & fees
Dec 14 - Dec 15
Hotel Tlaxcala
Double Room | In-room safe, desk, laptop workspace, blackout drapes
Hotel Mirante Tlaxcala

Hotel Mirante Tlaxcala

Hotel Mirante Tlaxcala
4.0 star property
Tlaxcala
9.6 out of 10, Exceptional, (91)
Surrounded by cultural landmarks like Regional Museum of Tlaxcala, this hotel offers a health club for post-sightseeing relaxation. Enjoy garden strolls, grab snacks at the deli, or unwind at the cafe with free WiFi and parking.
"Our stay in Tlaxcala was excellent. The breakfast and staff were top-notch and courteous. I will definitely stay here for future visits!"
United States
Janina
The price is ￥7,458
￥8,800 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Hotel Mirante Tlaxcala
Indoor pool
Hotel Cuamanco

Hotel Cuamanco

Hotel Cuamanco
3.0 star property
Huamantla
8.8 out of 10, Excellent, (91)
Located near Taurino Museum and Juarez Park, this hotel offers free WiFi and parking. After a refreshing swim, savor a delicious meal at the restaurant or relax with drinks at the bar. Nearby attractions make it an ideal base for exploration.
"Todo excelente "
Mexico
GABRIELA
The price is ￥4,289
￥5,061 total
includes taxes & fees
Dec 14 - Dec 15
Hotel Cuamanco
Exterior
Hotel GS Jerocs

Hotel GS Jerocs

Hotel GS Jerocs
3.0 star property
Tlaxcala
8.2 out of 10, Very Good, (349)
Experience authentic hospitality at this welcoming hotel featuring a restaurant serving Mexican cuisine, plus a bar and scenic terrace. Near Basilica of Ocotlan and Xicotencatl Theater, guests enjoy free WiFi and parking while exploring local attractions.
"Hotel is very nice and clean. The staff is very nice and accommodating."
Canada
Marisu
The price is ￥16,485
￥19,895 total
includes taxes & fees
Jan 13 - Jan 14, 2026
Hotel GS Jerocs
Indoor pool, open 7:00 AM to 10:00 PM, sun loungers
Hotel Senorial Tlaxcala

Hotel Senorial Tlaxcala

Hotel Senorial Tlaxcala
3.5 star property
Tlaxcala
8.8 out of 10, Excellent, (151)
Relax in an elegant hotel with indoor and children's pools, hot tub, and fitness center. Just minutes from Basilica of Ocotlan and Xicotencatl Theater, with easy access to cultural attractions. Free WiFi and parking enhance your Mexican adventure.
"Hotel overall was clean, safe and quiet. Ample amount of room. Staff was nice and hospitable. Definitely recommend. "
United States
Janie
Hotel Senorial Tlaxcala
Exterior
One Puebla Finsa

One Puebla Finsa

One Puebla Finsa
3.0 star property
Cuautlancingo
8.4 out of 10, Very Good, (685)
Experience Italian cuisine at Green Light restaurant in this accessible hotel just 15 minutes from Zócalo de Puebla. Free breakfast, WiFi, and parking make exploring Great Pyramid of Cholula and Outlet Puebla Premier easy and convenient.
"Excellent staff and accomodations."
United States
Terry
The price is ￥6,809
￥8,171 total
includes taxes & fees
Jan 4 - Jan 5, 2026
One Puebla Finsa
Elite Suite (Camaldoni) | Premium bedding, pillowtop beds, in-room safe, individually decorated
Villa Toscana ValQuirico Lofts & Suites Hotel Boutique

Villa Toscana ValQuirico Lofts & Suites Hotel Boutique

Villa Toscana ValQuirico Lofts & Suites Hotel Boutique
3.5 star property
Santeagueda
9.6 out of 10, Exceptional, (361)
Discover a boutique hotel in Tetlatlahuca offering complimentary WiFi and parking. Explore the countryside on hiking trails or horseback, then unwind with onsite spa services. The attentive staff receives consistent praise, and nearby Outlet Puebla Premier adds shopping convenience.
"The rooms were very nice, though the area is made to look like Italian towns tbe rooms were large and confortable highly recommend a stay at this hotel "
United States
Jose
The price is ￥22,616
￥26,687 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Villa Toscana ValQuirico Lofts & Suites Hotel Boutique
Breakfast and lunch served, Mexican cuisine
Hotel de La Loma

Hotel de La Loma

Hotel de La Loma
3.0 star property
Tlaxcala
8.8 out of 10, Excellent, (224)
This Mexican hotel offers El Mirador restaurant serving local cuisine for breakfast and lunch. Located near the Art Museum of Tlaxcala and Museo de la Memoria, guests appreciate the helpful staff and free parking during their cultural exploration.
"Great location, well situated"
United States
Anonymous traveler
The price is ￥7,989
￥9,502 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Hotel de La Loma
Comfort Loft | Individually decorated, individually furnished, free WiFi, bed sheets
Pietro Santo

Pietro Santo

Pietro Santo
2.0 star property
Santeagueda
9.4 out of 10, Exceptional, (136)
Located near Outlet Puebla Premier and Cacaxtla attractions, Pietro Santo apartments offer Smart TVs and free WiFi for a connected stay. Enjoy convenient access to Puebla Intl. Airport, just 22 minutes away, plus 24-hour front desk service.
"Very nice hotel. And excellent service. Valquirico is a wonderful destination for dining shopping and walking around. The hotel is located right in the center. "
United States
Carlos
Pietro Santo
Terrace/patio
La Bella Toscana Centro

La Bella Toscana Centro

La Bella Toscana Centro
2.0 star property
Santeagueda
9.8 out of 10, Exceptional, (95)
Enjoy the comforts of free WiFi and daily housekeeping at this convenient Tetlatlahuca hotel. Explore nearby Outlet Puebla Premier and ancient Cacaxtla ruins. The 24-hour front desk ensures assistance whenever needed.
"Excellent place to visit."
United States
Enrique
La Bella Toscana Centro
Arezzo | Terrace/patio
Porta Paradiso Albergo Boutique

Porta Paradiso Albergo Boutique

Porta Paradiso Albergo Boutique
2.5 star property
Santeagueda
9.6 out of 10, Exceptional, (121)
Immerse yourself in the entertainment district of Tetlatlahuca at this boutique hotel. Free WiFi and daily housekeeping create a comfortable stay while Outlet Puebla Premier and Cacaxtla attractions await nearby. The 24-hour front desk ensures round-the-clock service.
"Hotel is nice, very clean, comfortable and close to everything in Val’quirico."
United States
Christina
The price is ￥24,331
￥28,710 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Porta Paradiso Albergo Boutique
Apartment | Exterior
Castello di Carlo – Loft Carlo II.

Castello di Carlo – Loft Carlo II.

Castello di Carlo – Loft Carlo II.
2.0 star property
Val'Quirico
Immerse yourself in the tranquil atmosphere of this distinctive hotel with complimentary WiFi. Conveniently positioned near Outlet Puebla Premier and the ancient ruins of Cacaxtla, just 21 minutes from Puebla International Airport.
The price is ￥34,550
￥44,662 total
includes taxes & fees
Dec 15 - Dec 16
Castello di Carlo – Loft Carlo II.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Tlaxcala Hotel Reviews

Ramada Encore Puebla Mexico

Ramada Encore Puebla Mexico

10/10 Excellent
"Good"
Sandra L 1-night trip
Posted 8 days ago
Ramada Encore Puebla Mexico

More cheap stays in Santa Cruz Tlaxcala

Hotel Royal Puebla

Hotel Royal Puebla

Atilac San Felipe Hueyotlipan Puebla PUE
The price is ￥4,282 per night from Dec 14 to Dec 15
￥4,282
￥5,096 total
Dec 14 - Dec 15
includes taxes & fees
7.4/10 Good! (120 reviews)

Frequently asked questions

Where is the best place for a stay in Santa Cruz Tlaxcala?
Ramada Encore Puebla Mexico, located 17.6 mi (28.3 km) from the heart of Santa Cruz Tlaxcala, is a top choice for your stay based on our traveler data. Two other choices for your stay in the area are Marriott Puebla Hotel Meson del Angel and Plaza Poblana. See all available top hotels, or vacation rentals in Santa Cruz Tlaxcala.
What are some of the best vacation home rentals that Santa Cruz Tlaxcala has to offer?
Luxurious Casa Residencial Privada: This highly rated vacation home rental in Santa Cruz Tlaxcala offers a balcony and laundry facilities to help you feel comfortable in your new surroundings. It has 3 bedrooms in addition to a kitchen with a microwave and kitchenware. See all vacation rentals in Santa Cruz Tlaxcala.
If I need to cancel my hotel reservation in Santa Cruz Tlaxcala, will I receive a refund?
Yes, you'll find most hotel reservations are refundable if you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If your reservation is non-refundable, it might still be possible to cancel it and receive a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz Tlaxcala.
Where can I learn more about changing or cancelling my trip to Santa Cruz Tlaxcala?
To access more information about rescheduling or cancelling your trip to Santa Cruz Tlaxcala, head over to our customer service page.
How is it to stay in Santa Cruz Tlaxcala?
Visitors can enjoy all that Santa Cruz Tlaxcala has to offer including its parks. There are 213 hotels and other accommodations in the surrounding area. Find out more about Santa Cruz Tlaxcala.
What should I see while I'm in Santa Cruz Tlaxcala?
Places to visit in the wider area include Basilica of Ocotlan, Xicotencatl Theater, and La Malinche National Park. You'll also find Cacaxtla and Xicotencatl National Park in the area. Check out what more to see and do in Expedia's Santa Cruz Tlaxcala guide.
What's the weather like in Santa Cruz Tlaxcala?
The hottest months are usually April and May with an average temp of 61°F, while the coldest months are January and December with an average of 54°F. The rainiest months in Santa Cruz Tlaxcala are August, September, July, and June, with each month seeing an average of 10 inches of rainfall.

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