A beach with black volcanic rocks, clear turquoise water, and a distant shoreline with buildings.

Santa Cruz Island Vacation Rentals

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
In two months
In three months
In four months

Our top choices for Santa Cruz Island vacation rentals

1. Torre Mar Galapagos Boutique Suites

Torre Mar Galapagos Boutique Suites
3.0 star property
Puerto Ayora
9.4 out of 10, Exceptional, (27 reviews)
"The host was so nice, kind, and friendly."
United States
Maho
The price is ¥20,852
¥20,852 total
Sep 9 - Sep 10
Torre Mar Galapagos Boutique Suites

2. Suites

Suites
3.0 star property
Puerto Ayora
9.4 out of 10, Exceptional, (24 reviews)
"Check was early and friendly staff Room was super clean and comfortable"
United States
Judy
The price is ¥11,998
¥13,272 total
Sep 9 - Sep 10
Suites

3. Colmena Apartment in downtown Puerto Ayora, Santa Cruz

Colmena Apartment in downtown Puerto Ayora, Santa Cruz
Puerto Ayora
10.0 out of 10, Exceptional, (1 review)
The price is ¥18,635
¥28,279 total
Aug 30 - Aug 31
Colmena Apartment in downtown Puerto Ayora, Santa Cruz

4. Modern apartment with 18 feet ceilings and private terrace with view to a park

Modern apartment with 18 feet ceilings and private terrace with view to a park
Puerto Ayora
10.0 out of 10, Exceptional, (24 reviews)
"I highly recommend you stay here. Its is beautiful and also away from the crowd noise."
United States
Richard
The price is ¥17,918
¥24,289 total
Aug 29 - Aug 30
Modern apartment with 18 feet ceilings and private terrace with view to a park

5. Chic City Gateway: Spacious modern apartment in the Heart of Puerto Ayora

Chic City Gateway: Spacious modern apartment in the Heart of Puerto Ayora
Puerto Ayora
10.0 out of 10, Exceptional, (2 reviews)
"The place is perfect in every way, clean , spacious, great kitchen, comfortable beds, also the laundry facility is so helpful for longer stay. The host communication is excellent, immediate responds, great recommendations for the activities and local eats, location is also good , 10-15 minutes to walk to town center. we enjoyed our stay very much. highly recommend this place."
United States
Lihua
The price is ¥24,368
¥35,039 total
Sep 3 - Sep 4
Chic City Gateway: Spacious modern apartment in the Heart of Puerto Ayora

6. Galapagos Coliving Ecuador Casa Tuna

Galapagos Coliving Ecuador Casa Tuna
3.0 star property
Puerto Ayora
2.0 out of 10, (1 review)
"Beware of this scam, the owner did not receive our reservstion nor the money!"
United States
Maya
The price is ¥23,738
¥26,923 total
Aug 29 - Aug 30
Galapagos Coliving Ecuador Casa Tuna

7. TWO Bedrooms Apartment ON THE Ground Floor IN Ariana`s Galapagos Hostal

TWO Bedrooms Apartment ON THE Ground Floor IN Ariana`s Galapagos Hostal
Puerto Ayora
10.0 out of 10, Exceptional, (1 review)
"We enjoyed our 6-night stay at Ariana's. The apartment was large and comfortable. Bedroom air conditioners were whisper quiet. We especially enjoyed the rooftop terrace with its soft breezes. It’s a 20 minute walk to the big tortoise statue and a few minutes more to the Mlecon, or a 2 taxi ride."
Canada
Dean P.
The price is ¥10,990
¥15,824 total
Aug 29 - Aug 30
TWO Bedrooms Apartment ON THE Ground Floor IN Ariana`s Galapagos Hostal

8. Suite with spectacular ocean view, you will wake up to the sound of the sea.

Suite with spectacular ocean view, you will wake up to the sound of the sea.
Puerto Ayora
8.0 out of 10, Very Good, (1 review)
The price is ¥14,334
¥24,448 total
Sep 3 - Sep 4
Suite with spectacular ocean view, you will wake up to the sound of the sea.

9. Villa Galapagos

Villa Galapagos
2.5 star property
Puerto Ayora
6.0 out of 10, (1 review)
"着いて早々にダブルブッキングがわかった。これは施設というよりも、貴社のシステムの問題。前回も宿泊名簿に名前がなかったこともあり、強く改善をもとめる。"
Japan
アオアシカツオドリ
The price is ¥12,901
¥15,290 total
Sep 10 - Sep 11
Villa Galapagos

10. Spacious 6-bedroom building in superb Puerto Ayora with AC and no AC

Spacious 6-bedroom building in superb Puerto Ayora with AC and no AC
Puerto Ayora
10.0 out of 10, Exceptional, (1 review)
"Stay was great and I really enjoy Daniel’s helpful service— can’t wait to come back and stay again!"
United States
Will L.
The price is ¥15,927
¥21,501 total
Aug 30 - Aug 31
Spacious 6-bedroom building in superb Puerto Ayora with AC and no AC

11. ¡Bienvenido a tu hogar isleño en Galápagos!

¡Bienvenido a tu hogar isleño en Galápagos!
Puerto Ayora
The price is ¥13,060
¥16,245 total
Sep 11 - Sep 12
¡Bienvenido a tu hogar isleño en Galápagos!

12. Cozy 2-bedroom apartment in charming Puerto Ayora with AC, WiFi

Cozy 2-bedroom apartment in charming Puerto Ayora with AC, WiFi
Puerto Ayora
The price is ¥13,060
¥16,245 total
Sep 4 - Sep 5
Cozy 2-bedroom apartment in charming Puerto Ayora with AC, WiFi

13. TWO Bedrooms Apartment ON THE First Floor Forest View

TWO Bedrooms Apartment ON THE First Floor Forest View
Puerto Ayora
The price is ¥10,990
¥15,824 total
Aug 29 - Aug 30
TWO Bedrooms Apartment ON THE First Floor Forest View

14. 2-bedroom apartment with AC, WiFi in fabulous Puerto Ayora

2-bedroom apartment with AC, WiFi in fabulous Puerto Ayora
Puerto Ayora
The price is ¥10,830
¥14,015 total
Aug 31 - Sep 1
2-bedroom apartment with AC, WiFi in fabulous Puerto Ayora

15. FAMILY SUITE in Puerto Ayora

FAMILY SUITE in Puerto Ayora
Puerto Ayora
10.0 out of 10, Exceptional, (1 review)
"Great lodging with effective space for multiple groups of travelers. Location is perfect, off the tourist path, and easy to access by any taxis in Puerto Arroyo (just say you want to go to Parque Cascada). Groceries are available anywhere near the house, better produce quality found in the shops on Baltra Ave. Property manager is easy to communicate with and responds instantly."
United States
Nathan M.
The price is ¥31,854
¥36,314 total
Aug 29 - Aug 30
FAMILY SUITE in Puerto Ayora

16. A centrally located suite in Santa Cruz within easy reach of everything

A centrally located suite in Santa Cruz within easy reach of everything
Puerto Ayora
The price is ¥7,167
¥11,945 total
Aug 29 - Aug 30
A centrally located suite in Santa Cruz within easy reach of everything

17. NEAR THE SEE-DARWIN APARTMENT

NEAR THE SEE-DARWIN APARTMENT
Puerto Ayora
The price is ¥14,334
¥19,670 total
Aug 29 - Aug 30
NEAR THE SEE-DARWIN APARTMENT

18. Near the sea-Darwin Apartment

Near the sea-Darwin Apartment
Puerto Ayora
Near the sea-Darwin Apartment

19. Near Tortuga Bay Beach

Near Tortuga Bay Beach
Puerto Ayora
The price is ¥7,964
¥12,344 total
Sep 9 - Sep 10
Near Tortuga Bay Beach

20. Downtown Apartment

Downtown Apartment
Puerto Ayora
The price is ¥7,645
¥12,105 total
Aug 29 - Aug 30
Downtown Apartment
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Santa Cruz Island Hotel Reviews

Find out more about Santa Cruz Island

Search for holiday rentals in Santa Cruz Island on Expedia! You can easily find your home rentals, villas, holiday apartments in Santa Cruz Island using one of the methods below:

  • View our selection of featured holiday rentals in Santa Cruz Island
  • Use the map to find apartments and other holiday homes in the Santa Cruz Island neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Santa Cruz Island while they last

Look no further and take a look at our great range of rental properties in Santa Cruz Island!