Find hotels in Santa Clara from ¥6,494

Start date: Check-in selected.
To Date
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Compare 601 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Our top choices for Santa Clara hotels

Villa Botero By Casa Mojito B&B

3.0 star property
9.8 out of 10, Exceptional, (60)
"Wonderful little hotel. With only three "
Villa Botero By Casa Mojito B&B

La Maracuyá

4.0 star property
9.8 out of 10, Exceptional, (10)
"Nice place and nice ladies who run the place. Thoughtful touches "
La Maracuyá

Hotel La Compania Del Valle

5.0 star property
9.8 out of 10, Exceptional, (42)
"Great place to stay and relax Beautiful "
The price is ¥28,733
¥31,606 total
includes taxes & fees
Oct 7 - Oct 8
Hotel La Compania Del Valle

The Golden Frog Inn

3.0 star property
9.6 out of 10, Exceptional, (209)
"Staff was amazing, room was fantastic, and our experience was magical. "
The price is ¥12,990
¥14,289 total
includes taxes & fees
Oct 1 - Oct 2
The Golden Frog Inn

Cabaña Villa Victoria

2.5 star property
9.6 out of 10, Exceptional, (47)
"Great host. Lush garden view."
The price is ¥10,333
¥11,366 total
includes taxes & fees
Oct 21 - Oct 22
Cabaña Villa Victoria

The Buenaventura Golf & Beach Resort Panama, Autograph Collection

5.0 star property
9.2 out of 10, Wonderful, (661)
"Spectacular hotel right in front of the beach. Extremely friendly staff. Plenty of restaurant options with top notch food. I definitely recommend it!"
The price is ¥21,994
¥24,193 total
includes taxes & fees
Oct 21 - Oct 22
The Buenaventura Golf & Beach Resort Panama, Autograph Collection

Caracoral Hotel Boutique & Spa

3.0 star property
9.6 out of 10, Exceptional, (60)
"Beautiful hotel and wonderful staff. We really enjoyed our stay."
Caracoral Hotel Boutique & Spa

La Casita de Don Daniel

2.0 star property
9.2 out of 10, Wonderful, (42)
"An amazing stay with a host that went above and beyond. "
La Casita de Don Daniel

El litoral

3.0 star property
9.6 out of 10, Exceptional, (59)
"An excellent place to stay on a first visit to Coronado. Anne-Marie has great knowledge of the area which she is happy to share with guests."
The price is ¥18,673
¥20,540 total
includes taxes & fees
Sep 25 - Sep 26
El litoral

Manglar Lodge

3.0 star property
8.8 out of 10, Excellent, (202)
"Nice place I’d go back"
The price is ¥9,841
¥10,825 total
includes taxes & fees
Sep 25 - Sep 26
Manglar Lodge

Nomada Republic Hotel El Valle

3.0 star property
9.0 out of 10, Wonderful, (38)
"An excellent hotel with great views (on a sunny day). The drive into town is pretty short, so it's a good spot that's both convenient and quiet"
The price is ¥15,211
¥16,732 total
includes taxes & fees
Sep 25 - Sep 26
Nomada Republic Hotel El Valle

Acuarela Hostal - Hostel

2.0 star property
8.6 out of 10, Excellent, (23)
"Was a lovely lovely stay. The breakfast was excellent, and the family staff was so kind and accommodating. "
The price is ¥5,904
¥6,494 total
includes taxes & fees
Sep 25 - Sep 26
Acuarela Hostal - Hostel

Hotel Eclipse

3.0 star property
8.6 out of 10, Excellent, (67)
"The property and furnishings are showing their age. Needs upgrades and maintenance. But staff was great and did a good job keeping it clean. Didn't utilize the restaurant so cannot comment on it."
Hotel Eclipse

Mi Casa Asi de Grande

3.0 star property
8.4 out of 10, Very Good, (21)
"Staff very friendly and welcoming. The chef was very friendly. Room was clean but very dated. No hot water was the no no for my wife. Stepping back to the seventies. Felt secure."
Mi Casa Asi de Grande

San Carlos Beach Inn

3.0 star property
8.4 out of 10, Very Good, (29)
"Nice place to stay "
San Carlos Beach Inn

Casa Madre Tierra

3.0 star property
9.8 out of 10, Exceptional, (27)
"The hotel is beautiful and the staff is amazing. We had a lovely stay in a 2 room suite next to the grand salon. We had access to our own kitchen and living space. The pool was perfect for our 2 daughters. The food was outstanding. We had a lovely stay and highly recommend. "
The price is ¥24,271
¥26,881 total
includes taxes & fees
Sep 26 - Sep 27
Casa Madre Tierra

Casa Swell Coronado

2.5 star property
10.0 out of 10, Exceptional, (27)
"Lovely property, excellent hosts!"
Casa Swell Coronado

Hotel Las Catalinas Antón

2.5 star property
8.4 out of 10, Very Good, (25)
"The hotel is very unique and quaint, very warm and comfortable. The location is so charming in the old town. There was a little parade and the church bells ring with the Sunday morning. A great staff so helpful and kind. We can not wait to return. "
The price is ¥6,310
¥6,942 total
includes taxes & fees
Sep 25 - Sep 26
Hotel Las Catalinas Antón

Hotel Coronado Inn

3.0 star property
8.2 out of 10, Very Good, (77)
"Beautiful space. Friendly staff"
Hotel Coronado Inn

Hotel Campestre

3.0 star property
8.2 out of 10, Very Good, (242)
"Very relaxing hotel. The place is not luxurious, but it very serene. "
The price is ¥11,300
¥12,645 total
includes taxes & fees
Oct 9 - Oct 10
Hotel Campestre
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Santa Clara attractions

Playa Blanca
Playa Blanca

Playa Blanca

Nothing says vacation like spending a lazy day at Playa Blanca, a popular beach in Rio Hato. Amble around this family-friendly area's seaside or experience its entertainment venues.

Top Santa Clara Hotel Reviews

More cheap stays in Santa Clara

More cheap stays in Santa Clara

Frequently asked questions

Where is the best place to stay in Santa Clara?

Villa Botero By Casa Mojito B&B is one of the top choices for your stay based on our traveler data. This B&B offers an outdoor pool and free parking. Las Sirenas de Santa Clara is another good option for your visit. See all available top hotels, or vacation rentals in Santa Clara.

What's the top vacation rental in Santa Clara?

Panama Santa Clara Beach Residence: Visitors give good reviews to this Santa Clara vacation home rental, which is located on the beach and has a patio, a pool table, and a barbecue grill to put you at ease in your new surroundings. It has 4 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family. See all vacation rentals in Santa Clara.

If I need to cancel my hotel reservation in Santa Clara, will I receive a refund?

Yes! Most room reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your check-in date. If your reservation is non-refundable, you might still have the option to cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Clara.

Where can I learn more about changing or cancelling my trip to Santa Clara?

For more details about updating your trip to Santa Clara or cancelling it, click here.

What is the top LGBTQ-friendly place to stay in Santa Clara?

Villa Botero By Casa Mojito B&B is a top LGBTQ-friendly B&B that features free WiFi and free parking. See all available hotels listed as LGBTQ-friendly in Santa Clara.

What's the best pet-friendly hotel in Santa Clara?

Villa Botero By Casa Mojito B&B is a top B&B for people traveling with their pets, and offers an outdoor pool and a bar/lounge for its human guests. See more pet-friendly hotel accommodations in Santa Clara.

What are some hotels with pools in Santa Clara?

Villa Botero By Casa Mojito B&B: B&B located near Playa Blanca. Features spa services, an outdoor pool, and a snack bar/deli. Gran Evenia Bijao & Convention Center and Hotel Riu Playa Blanca - All Inclusive are two additional hotels with an onsite pool. View all hotels with pools in Santa Clara.

What is the best accommodation for staying close to Tocumen International Airport (PTY)?

Crowne Plaza Panama Airport is a popular 4-star hotel featuring a restaurant and an outdoor pool. It's located a short 0.3 mi (0.4 km) from Tocumen Intl. Airport. Other good options within close proximity to the airport include Riande Aeropuerto Hotel & Casino and Express Inn Panama International Airport Hostel.

What is staying in Santa Clara like?

Visitors can enjoy all that Santa Clara has to offer including its beaches. Tourists to the city can also enjoy its scenic landscape. A top sight in the area is Playa Blanca. In Santa Clara, there are 14 hotels and other accommodations to choose from. Find out more about Santa Clara.

What is there to see in Santa Clara?

A favorite place to visit is Santa Clara Beach. Additionally, you'll find Playa Blanca in the area. Check out what more to see and do in Expedia's Santa Clara guide.

What's the seasonal weather like in Santa Clara?

The hottest months are usually March and April with an average temp of 79°F, while the coldest months are January and December with an average of 78°F. The rainiest months in Santa Clara are October, November, September, and August, with each month seeing an average of 13 inches of rainfall.

Explore a world of travel with Expedia

Explore a world of travel with Expedia