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Find hotels in Uptown, San Antonio from ¥8,402

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Our top choices for Uptown hotels

Wyndham Garden San Antonio Airport

Wyndham Garden San Antonio Airport
3.0 star property
Uptown
9.4 out of 10, Exceptional, (1008)
"Great area."
United States
Ricardo
The price is ¥14,694
¥17,370 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Wyndham Garden San Antonio Airport

Best Western Garden Inn

Best Western Garden Inn
2.5 star property
Uptown
8.2 out of 10, Very Good, (1003)
"Clean room, friendly and helpful staff."
United States
Robyn
The price is ¥9,329
¥10,893 total
includes taxes & fees
Dec 23 - Dec 24
Best Western Garden Inn

Drury Plaza Hotel San Antonio Airport

Drury Plaza Hotel San Antonio Airport
3.0 star property
Uptown
9.4 out of 10, Exceptional, (1930)
"Rooms and public areas were nice & clean"
United States
Michelle
The price is ¥14,112
¥16,681 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Drury Plaza Hotel San Antonio Airport

Hampton Inn & Suites San Antonio-Airport

Hampton Inn & Suites San Antonio-Airport
2.5 star property
Uptown
8.4 out of 10, Very Good, (1758)
"A good stay for the money."
United States
William S
The price is ¥12,334
¥14,908 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Hampton Inn & Suites San Antonio-Airport

Crowne Plaza San Antonio Airport by IHG

Crowne Plaza San Antonio Airport by IHG
3.5 star property
Uptown
8.4 out of 10, Very Good, (1477)
"Nice courteous staff, clean room"
United States
Tina
The price is ¥11,448
¥13,531 total
includes taxes & fees
Dec 17 - Dec 18
Crowne Plaza San Antonio Airport by IHG

Red Roof Inn San Antonio - Airport

Red Roof Inn San Antonio - Airport
2.0 star property
Uptown
8.2 out of 10, Very Good, (1120)
"Staff was so friendly "
United States
Shqiprim
The price is ¥7,149
¥8,452 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Red Roof Inn San Antonio - Airport

Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

Heritage Inn & Suites San Antonio Airport, Trademark Wyndham
2.5 star property
Uptown
9.4 out of 10, Exceptional, (1508)
"The room was clean very quiet would stay again"
United States
Llewellyn
The price is ¥12,396
¥14,654 total
includes taxes & fees
Dec 14 - Dec 15
Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

Homewood Suites by Hilton San Antonio Airport

Homewood Suites by Hilton San Antonio Airport
3.0 star property
Uptown
8.6 out of 10, Excellent, (1001)
"Great stay"
United States
Meredith
The price is ¥15,557
¥18,815 total
includes taxes & fees
Jan 10 - Jan 11, 2026
Homewood Suites by Hilton San Antonio Airport

Embassy Suites by Hilton San Antonio Airport

Embassy Suites by Hilton San Antonio Airport
3.5 star property
Uptown
8.8 out of 10, Excellent, (1061)
"Great stay!"
United States
darryl
The price is ¥18,564
¥21,944 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Embassy Suites by Hilton San Antonio Airport

Spark by Hilton San Antonio Airport

Spark by Hilton San Antonio Airport
2.0 star property
Uptown
8.6 out of 10, Excellent, (1019)
"Great time staying at this location."
United States
Amy
The price is ¥9,967
¥11,834 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Spark by Hilton San Antonio Airport

Comfort Suites San Antonio North - Stone Oak

Comfort Suites San Antonio North - Stone Oak
2.5 star property
Uptown
8.6 out of 10, Excellent, (1002)
"Excellent stay, great place highly recommended "
United States
Cesar
The price is ¥11,863
¥13,851 total
includes taxes & fees
Dec 15 - Dec 16
Comfort Suites San Antonio North - Stone Oak

SureStay Plus Hotel by Best Western San Antonio North

SureStay Plus Hotel by Best Western San Antonio North
2.5 star property
Uptown
7.0 out of 10, Good, (1000)
"The staff members were very helpful and friendly, my room was clean and check-in was a smooth process "
United States
Reginald
The price is ¥7,196
¥8,402 total
includes taxes & fees
Dec 15 - Dec 16
SureStay Plus Hotel by Best Western San Antonio North

Home2 Suites by Hilton San Antonio Airport, TX

Home2 Suites by Hilton San Antonio Airport, TX
3.0 star property
Uptown
8.6 out of 10, Excellent, (1002)
"Very good stay "
United States
Roberto
The price is ¥12,334
¥14,580 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Home2 Suites by Hilton San Antonio Airport, TX

Holiday Inn Express San Antonio-Airport by IHG

Holiday Inn Express San Antonio-Airport by IHG
2.5 star property
Uptown
9.4 out of 10, Exceptional, (1007)
"Great place. Clean and friendly staff."
Mexico
Jose
The price is ¥17,093
¥20,204 total
includes taxes & fees
Dec 21 - Dec 22
Holiday Inn Express San Antonio-Airport by IHG

Courtyard by Marriott San Antonio Airport

Courtyard by Marriott San Antonio Airport
3.0 star property
Uptown
8.4 out of 10, Very Good, (1000)
"Very friendly and courteous staff, great breakfast."
United States
Viju
The price is ¥13,957
¥16,499 total
includes taxes & fees
Dec 21 - Dec 22
Courtyard by Marriott San Antonio Airport

Hilton Garden Inn San Antonio Airport South

Hilton Garden Inn San Antonio Airport South
3.0 star property
Uptown
8.4 out of 10, Very Good, (1001)
"Friendly Staff and Clean Room"
United States
Patrick
The price is ¥11,872
¥14,302 total
includes taxes & fees
Dec 21 - Dec 22
Hilton Garden Inn San Antonio Airport South

Home2 Suites by Hilton San Antonio North-Stone Oak, TX

Home2 Suites by Hilton San Antonio North-Stone Oak, TX
3.0 star property
Uptown
8.8 out of 10, Excellent, (874)
"Clean and nice rooms, very nice breakfast although not perfect"
United States
Youcai
The price is ¥12,797
¥15,126 total
includes taxes & fees
Dec 19 - Dec 20
Home2 Suites by Hilton San Antonio North-Stone Oak, TX

Marriott San Antonio Airport

Marriott San Antonio Airport
4.0 star property
Uptown
8.6 out of 10, Excellent, (1000)
"Great hotel"
United States
Kassie
The price is ¥17,407
¥20,576 total
includes taxes & fees
Dec 28 - Dec 29
Marriott San Antonio Airport

Estancia del Norte San Antonio, Tapestry Collection by Hilton

Estancia del Norte San Antonio, Tapestry Collection by Hilton
3.5 star property
Uptown
8.8 out of 10, Excellent, (1000)
"Love it- my favorite place to stay when in town!! Bartenders are the best!!!"
United States
Marisa
The price is ¥21,048
¥24,879 total
includes taxes & fees
Jan 10 - Jan 11, 2026
Estancia del Norte San Antonio, Tapestry Collection by Hilton

Hilton Garden Inn San Antonio Airport

Hilton Garden Inn San Antonio Airport
3.0 star property
Uptown
8.0 out of 10, Very Good, (1000)
"Staff is outstanding!"
United States
David
The price is ¥13,674
¥16,164 total
includes taxes & fees
Dec 21 - Dec 22
Hilton Garden Inn San Antonio Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Uptown

Find the best Uptown areas and neighborhoods for the activities you enjoy most.

Downtown San Antonio

Explore the heart of San Antonio with top attractions like the Alamo and River Walk, or enjoy kayaking and bicycling to the World Heritage Missions. Discover historic sites, theaters, and shopping at Rivercenter, all easily accessible by public transit.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Medical Center District

While visiting Medical Center District, you might make a stop by sights like USAA Corporate Office Headquarters and The San Antonio Art Institute.

Stone Oak

Travelers come to Stone Oak for its abundant dining options, and you can see top attractions like Shops at Hardy Oak and Alta Vista while you're in town.

Northwest Side

While visiting Northwest Side, you might make a stop by sights like Huebner Oaks and Crystal Ice Palace.

Top Uptown Hotel Reviews

Explore a world of travel with Expedia

Frequently asked questions

What's it like in Uptown?
Guests are sure to enjoy their time checking out all that San Antonio's Uptown neighborhood has to offer. Are you looking for Uptown travel tips? Be sure to check out Marion Koogler McNay Art Museum and Alamo Quarry Market while you're in the neighborhood.
What's the best accommodation in Uptown?
Based on Expedia customer reviews, Heritage Inn & Suites San Antonio Airport, Trademark Wyndham is the highest ranked property in Uptown. This hotel offers free breakfast and an outdoor pool. Other favorite options in the area include Wyndham Garden San Antonio Airport and Drury Plaza Hotel San Antonio Airport.
How many hotels will I be able to find in the Uptown area?
Expedia has 373 hotels and other accommodations in Uptown to choose from, making this an ideal home base for exploring the greater San Antonio area.
If I need to cancel my hotel reservation in Uptown, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it might still be possible to cancel it and get a refund within a 24-hour period of booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view the top deals on offer in Uptown.
Where can I learn more about changing or cancelling my trip to Uptown?
To find more details about picking new dates or cancelling your trip to Uptown, click here.
What can I see and do in this San Antonio neighborhood?
Uptown's sights and attractions like Toilet Seat Museum, Marion Koogler McNay Art Museum, and Parchman Stremmel Galleries offer insight into the local culture. You could also plan a visit to Alamo Quarry Market or San Antonio Zoo and Aquarium while you're in the neighborhood. A few places to visit in the area around Uptown include Harry B Orem Stadium, Quarry Golf Club, and Regal Alamo Quarry. McDermott Center and UIW Tennis Center are also worth a visit when you're out sightseeing in San Antonio.