Potosi Vacation Rentals

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Dec 10 - Dec 11
Tomorrow
Dec 11 - Dec 12
This weekend
Dec 12 - Dec 14
Next weekend
Dec 19 - Dec 21

Our top choices for Potosi vacation rentals

Outdoor dining
Lighted Hot Tub w/ 4 BD/2.5 Baths and VERY close to town.

Lighted Hot Tub w/ 4 BD/2.5 Baths and VERY close to town.

2.0 star property
Galena
10.0 out of 10, Exceptional, (72)
"The location is perfect just about a mile outside of town! The house was very clean and spacious. Beds were super comfortable. We had a great stay!"
United States
Kara D.
The price is ￥54,527
￥88,371 total
includes taxes & fees
Dec 14 - Dec 15
Lighted Hot Tub w/ 4 BD/2.5 Baths and VERY close to town.
Smart TV
Masterpiece on Main #3

Masterpiece on Main #3

2.0 star property
Downtown Dubuque
9.4 out of 10, Exceptional, (3)
"It was as pictured and the area was perfect. It downtown Dubuque and the farmers market was great and well as the Sunshine Family Restaurant. "
United States
Ann P.
Masterpiece on Main #3
Microwave, stovetop
Charming 1-bedroom apartment in fabulous Downtown Galena with WiFi, AC

Charming 1-bedroom apartment in fabulous Downtown Galena with WiFi, AC

Galena Historic District
9.4 out of 10, Exceptional, (9)
"Great location, good sleeping options "
United States
Dr. Sheila S.
The price is ￥21,811
￥35,827 total
includes taxes & fees
Dec 18 - Dec 19
Charming 1-bedroom apartment in fabulous Downtown Galena with WiFi, AC
Fridge, microwave, oven, stovetop
1157#3 / Tiny studio, Great Location, Dubuque

1157#3 / Tiny studio, Great Location, Dubuque

2.0 star property
Downtown Dubuque
9.0 out of 10, Wonderful, (12)
"Very nice property and very affordable. "
United States
Jennifer C.
The price is ￥6,699
￥16,751 total
includes taxes & fees
Dec 14 - Dec 15
1157#3 / Tiny studio, Great Location, Dubuque
Outdoor spa tub
Hot Tub 2-bedroom 2 full bath in lovely Galena countryside

Hot Tub 2-bedroom 2 full bath in lovely Galena countryside

Galena
10.0 out of 10, Exceptional, (12)
"What a beautiful property. Clean, private, and a perfect get-away for my family. My parents loved the house so much we almost had to drag them out! We loved everything about it, but my favorite part was definitely the hottub and the fire pit outside. Would definitely love to come back in the future!"
United States
Mary
The price is ￥33,873
￥66,454 total
includes taxes & fees
Dec 15 - Dec 16
Hot Tub 2-bedroom 2 full bath in lovely Galena countryside
Living area
115#303 / Vintage Meets Modern: Contemporary Loft

115#303 / Vintage Meets Modern: Contemporary Loft

Downtown Dubuque
10.0 out of 10, Exceptional, (12)
"We enjoyed our stay! Location was great for us. Very clean property. We will stay again next time we are in town. "
United States
Lydia K.
115#303 / Vintage Meets Modern: Contemporary Loft
Interior
An Artistic retreat in the heart of downtown Galena

An Artistic retreat in the heart of downtown Galena

Galena
10.0 out of 10, Exceptional, (27)
"Lovely place to stay at while visiting Galena! My wife and I absolutely loved our stay."
United States
Alex N.
The price is ￥33,534
￥41,845 total
includes taxes & fees
Dec 16 - Dec 17
An Artistic retreat in the heart of downtown Galena
Property grounds
1129#1- Market view studio/steps Millwork district

1129#1- Market view studio/steps Millwork district

Downtown Dubuque
9.6 out of 10, Exceptional, (44)
"Walking distance to restaurants and bars, clean and comfortable. We will definitely stay here again."
United States
Cindy L.
The price is ￥7,322
￥18,495 total
includes taxes & fees
Dec 14 - Dec 15
1129#1- Market view studio/steps Millwork district
Interior
Wooden Head Cabin Early1800's Log Cabin with a View and Modern Amenities

Wooden Head Cabin Early1800's Log Cabin with a View and Modern Amenities

Saint Donatus
9.2 out of 10, Wonderful, (16)
"I stayed overnight with a friend is this cabin. Everything was super cute right down to the sign at the drive entrance showing you how far you were from certain places… including the Beer Barn! Highly recommend. "
United States
Amanda B.
The price is ￥56,084
￥67,394 total
includes taxes & fees
Dec 14 - Dec 15
Wooden Head Cabin Early1800's Log Cabin with a View and Modern Amenities
Fridge, microwave, oven, stovetop
Cheerful home by Millwork District/Farmers Market

Cheerful home by Millwork District/Farmers Market

2.0 star property
Historic Millwork District
9.8 out of 10, Exceptional, (19)
"Extremely clean and well stocked house, very comfortable and enjoyable stay."
United States
Julie I.
The price is ￥15,839
￥37,587 total
includes taxes & fees
Dec 15 - Dec 16
Cheerful home by Millwork District/Farmers Market
Private kitchen
1103#201-Charming 2-bedroom apartment with AC, WiFi in brilliant Dubuque

1103#201-Charming 2-bedroom apartment with AC, WiFi in brilliant Dubuque

Downtown Dubuque
9.8 out of 10, Exceptional, (8)
"The property is conveniently located with food and entertainment close by, and the host provides all essentials, as well as thoughtful notes/labels to make it easier to feel at home."
United States
Amanda G.
The price is ￥11,291
￥28,453 total
includes taxes & fees
Dec 21 - Dec 22
1103#201-Charming 2-bedroom apartment with AC, WiFi in brilliant Dubuque
Fridge, microwave, oven, stovetop
1127 / Downtown Dubuque, first floor, free parking

1127 / Downtown Dubuque, first floor, free parking

2.0 star property
Downtown Dubuque
10.0 out of 10, Exceptional, (7)
"Great stay! The apartment was clean, comfortable, and in the perfect location. The host was friendly and easy to communicate with. I’d definitely stay here again."
United States
Emily W.
The price is ￥17,137
￥34,723 total
includes taxes & fees
Jan 9 - Jan 10, 2026
1127 / Downtown Dubuque, first floor, free parking
Fridge, microwave, oven, stovetop
Two Bedroom Apartment Overlooking Main Street with One Designated Parking Spot

Two Bedroom Apartment Overlooking Main Street with One Designated Parking Spot

Galena Historic District
9.8 out of 10, Exceptional, (10)
"Great location and Amy was great host. Loved how centrally it was to everything!"
United States
Robert B.
The price is ￥35,143
￥62,507 total
includes taxes & fees
Dec 11 - Dec 12
Two Bedroom Apartment Overlooking Main Street with One Designated Parking Spot
Fridge, microwave, oven, stovetop
The Nook: Downtown Galena Cottage w/ hot tub & fire pit!

The Nook: Downtown Galena Cottage w/ hot tub & fire pit!

Galena
10.0 out of 10, Exceptional, (130)
"Amazing yard, nice location, great communication from property manager."
United States
Brian C.
The price is ￥24,000
￥56,943 total
includes taxes & fees
Dec 16 - Dec 17
The Nook: Downtown Galena Cottage w/ hot tub & fire pit!
Fridge, microwave, oven, stovetop
Annie`s on Adair - NO Step Entry

Annie`s on Adair - NO Step Entry

Dubuque
10.0 out of 10, Exceptional, (2)
"The property was clean and comfortable with modern finishes. It was better than we expected. Possibly the best rental we have experienced."
United States
Chuck L.
The price is ￥14,021
￥36,816 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Annie`s on Adair - NO Step Entry
Fridge, microwave, oven, stovetop
One Bedroom Apartment Overlooking Main Street with One Designated Parking Spot

One Bedroom Apartment Overlooking Main Street with One Designated Parking Spot

Galena Historic District
9.8 out of 10, Exceptional, (18)
"Wonderful. The whole stay was great."
United States
Thomas
The price is ￥21,030
￥42,064 total
includes taxes & fees
Dec 11 - Dec 12
One Bedroom Apartment Overlooking Main Street with One Designated Parking Spot
Fridge, microwave, oven, stovetop
1129#3 / Ken’s place-cute / Free Parking

1129#3 / Ken’s place-cute / Free Parking

Downtown Dubuque
9.2 out of 10, Wonderful, (10)
"Very nice stay for a short while. It was great having off street parking. "
United States
elise h.
The price is ￥7,634
￥18,845 total
includes taxes & fees
Dec 14 - Dec 15
1129#3 / Ken’s place-cute / Free Parking
Microwave, oven, stovetop
Cozy Bluff St Escape - Downtown

Cozy Bluff St Escape - Downtown

Dubuque
9.4 out of 10, Exceptional, (3)
"Nicely decorated and centrally located to the downtown area! Easy check-in! "
United States
Melissa R.
The price is ￥13,408
￥32,582 total
includes taxes & fees
Dec 11 - Dec 12
Cozy Bluff St Escape - Downtown
Fridge, microwave, oven, stovetop
Large & Private w/King Bed Great Location

Large & Private w/King Bed Great Location

Dubuque
9.2 out of 10, Wonderful, (5)
"Beautiful property! "
United States
Jeffrey H.
The price is ￥12,463
￥28,790 total
includes taxes & fees
Dec 15 - Dec 16
Large & Private w/King Bed Great Location
Fridge, microwave, oven, stovetop
Amazing! 2 Bed Townhouse in the HEART of Dbq!

Amazing! 2 Bed Townhouse in the HEART of Dbq!

Dubuque
10.0 out of 10, Exceptional, (38)
"Great property. Close to what we needed to do!!"
United States
Jennifer
The price is ￥14,177
￥31,058 total
includes taxes & fees
Dec 14 - Dec 15
Amazing! 2 Bed Townhouse in the HEART of Dbq!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Potosi Hotel Reviews

Hotel Galena

Hotel Galena

10/10 Excellent
"Breakfast was good and many options available. Room was very clean and bed was comfortable. Location to main street was excellent. Only drawback was not being able to control the thermostate. When i got cold at 3 am...i didnt want to call and wake anyone to adjust the temperature. "
Kelly 3-night trip
Posted 1 day ago
Hotel Galena

Find out more about Potosi

Search for holiday rentals in Potosi on Expedia! You can easily find your home rentals, villas, holiday apartments in Potosi using one of the methods below:

  • View our selection of featured holiday rentals in Potosi
  • Use the map to find apartments and other holiday homes in the Potosi neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Potosi while they last

Look no further and take a look at our great range of rental properties in Potosi!

Frequently asked questions

Can I find a vacation rental in Potosi?

Yes, there are vacation rentals near well known attractions in Potosi, or you can choose a more remote option if you're looking for a relaxing stay. Potosi is known for its museums.

What are some of the best vacation rentals that Potosi has to offer?

Lighted Hot Tub w/ 4 BD/2.5 Baths and VERY close to town.: Visitors like this Potosi vacation home rental. It is located in a rural location and has a patio, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a selection of games and a hot tub.

What’s there to see and do in Potosi?

Mississippi River and Grant River are a couple of scenic spots to enjoy the outdoors, whereas National Brewery Museum is one of the cultural attractions. In the larger area, you’ll find Whispering Bluffs Winery and Dickeyville Grotto.

What’s a vacation rental in Potosi like?

Vacation rentals are privately owned properties where you can stay for a long or short time in Potosi. Vacation rentals offer extras like kitchens and laundry facilities so you'll feel just like you're staying in your own home. If you're concerned about cleanliness, a vacation rental can provide a sense of seclusion away from public hotel elevators and lobbies bustling with people while still allowing you the excitement and enjoyment of travel. You'll also find more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a great choice for small groups.