Find hotels in Palmyra, MO from ￥10,377

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Dec 15 - Dec 16
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Dec 16 - Dec 17
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Dec 19 - Dec 21
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Dec 26 - Dec 28

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Our top choices for Palmyra hotels

Standard Single Room, 2 Queen Beds, Non Smoking | Iron/ironing board, free WiFi, bed sheets
The Junction Inn

The Junction Inn

The Junction Inn
2.0 star property
Perry
6.4 out of 10, (37)
This roadside hotel provides a convenient 24-hour front desk and complimentary amenities. Located close to Bill Trower Memorial Park and Perry Park, it serves as a practical base for exploring local attractions.
"Clean, affordable, friendly & easy access of hwy & airport/rental car area!"
United States
Staci
The Junction Inn
Free WiFi, bed sheets
Cannon Dam Cabins

Cannon Dam Cabins

Cannon Dam Cabins
3.0 star property
Perry
9.2 out of 10, Wonderful, (13)
Charming cabins with private patios near Robert E Allen Recreation Area. Take a dip in the indoor pool after exploring Perry Park, then prepare simple meals with in-room microwaves while enjoying complimentary WiFi.
"Love this place! Great location to the launch ramp and Dog friendly. Management is amazing and kind and knowledgeable of the area. "
United States
stacy
The price is ￥16,002
￥17,022 total
includes taxes & fees
Dec 16 - Dec 17
Cannon Dam Cabins
Lobby
FairBridge Inn Express, Monroe City

FairBridge Inn Express, Monroe City

FairBridge Inn Express, Monroe City
2.0 star property
Monroe City
8.6 out of 10, Excellent, (437)
This business-friendly motel offers complimentary self-serve breakfast each morning, with the added convenience of free Wi-Fi and parking. Enjoy a practical base for exploring Monroe City in a straightforward, comfortable setting.
"Just a plain little hotel. Nothing fancy, but the place is clean, the beds are firm and the price is reasonable. Small town location limits your food choices a bit, but I don't go for the food anyway."
United States
Edward
The price is ￥15,581
￥16,921 total
includes taxes & fees
Dec 16 - Dec 17
FairBridge Inn Express, Monroe City
Desk, laptop workspace, iron/ironing board, free WiFi
Baymont by Wyndham Hannibal

Baymont by Wyndham Hannibal

Baymont by Wyndham Hannibal
2.5 star property
Hannibal
6.4 out of 10, (736)
Located near Mississippi River and West Ely Park, this hotel offers free breakfast, WiFi, and parking. Enjoy a morning swim in the indoor pool or workout at the health club. Guests praise the helpful staff and clean rooms at this business-friendly retreat.
" There actually was a pool & there actually was a hot breakfast. It didn't just say there was & not have what was listed. One of the best we've been to as of late. Would stay again if in the area. "
United States
Thomas
The price is ￥10,128
￥11,709 total
includes taxes & fees
Dec 16 - Dec 17
Baymont by Wyndham Hannibal
Exterior
Super 8 by Wyndham Hannibal

Super 8 by Wyndham Hannibal

Super 8 by Wyndham Hannibal
2.0 star property
Hannibal
7.2 out of 10, Good, (1000)
Set in peaceful surroundings, this Hannibal motel offers a seasonal outdoor pool and easy access to hiking trails. Guests praise the helpful staff and clean accommodations. Complimentary breakfast, WiFi, and parking enhance the value while nearby parks provide outdoor recreation options.
"My stay was excellent staff very friendly and breakfast was always great "
United States
Sherrie
The price is ￥9,115
￥10,468 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Super 8 by Wyndham Hannibal
Free self parking
Kennedys Red Barn Inn

Kennedys Red Barn Inn

Kennedys Red Barn Inn
2.5 star property
Perry
9.2 out of 10, Wonderful, (27)
Relax at this charming inn offering free breakfast, WiFi, and parking. After exploring nearby Robert E Allen Recreation Area, unwind in the hot tub or enjoy a meal at the on-site restaurant.
"The hosts were very accommodating and attentive to their guest needs. Wonderful place to stay!"
United States
Jeff
The price is ￥13,395
￥14,249 total
includes taxes & fees
Dec 16 - Dec 17
Kennedys Red Barn Inn
Exterior
Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
2.5 star property
Hannibal
9.6 out of 10, Exceptional, (1004)
This business-friendly hotel offers an indoor pool and fitness center near Hospital Park. Wake up to complimentary breakfast before exploring local attractions. Guests consistently praise the comfortable beds and helpful staff, plus enjoy free WiFi and parking.
"Great area"
United States
kelvin
The price is ￥15,760
￥18,258 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Sleep Inn & Suites Hannibal West
Premium bedding, pillowtop beds, desk, laptop workspace
AmericInn by Wyndham Quincy

AmericInn by Wyndham Quincy

AmericInn by Wyndham Quincy
2.0 star property
Quincy
7.6 out of 10, Good, (296)
Take a dip in the indoor pool after a busy day exploring local attractions. Located near Quincy Mall with complimentary breakfast, WiFi and parking. Just minutes from Mississippi River and Quincy Station, with helpful staff ready to assist your stay.
"Staff very friendly, room clean"
United States
Melanie
The price is ￥11,779
￥13,426 total
includes taxes & fees
Dec 21 - Dec 22
AmericInn by Wyndham Quincy
Lobby sitting area
Howard Johnson BY Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal
2.0 star property
Hannibal
7.2 out of 10, Good, (152)
This comfortable Howard Johnson hotel offers convenient amenities including an indoor pool, free WiFi, and complimentary parking. Located near West Ely Park and Sodalis Nature Preserve, guests consistently praise the friendly staff and clean accommodations for a pleasant Missouri getaway.
"The gentleman at the front desk was extremely nice and did everything to make my stay wonderful. The breakfast was awesome. The pool was sooo nice. The exercise room was great. I cannot say anything bad about this hotel. This was the first time I stayed here and I will be coming back every three months.!"
United States
Shawn
The price is ￥9,029
￥10,441 total
includes taxes & fees
Dec 16 - Dec 17
Howard Johnson BY Wyndham Hannibal
55-inch TV with cable channels, Netflix, Hulu
Riverside Inn Hannibal

Riverside Inn Hannibal

Riverside Inn Hannibal
2.5 star property
Hannibal
9.4 out of 10, Exceptional, (165)
Quaint guesthouse offering free WiFi, parking, and Netflix just 5 minutes from the Mississippi River. Explore Mark Twain Boyhood Home and Museum or catch a show at nearby Planters Barn Theater after a day of riverside wandering.
"Great place to stay!"
United States
Sandy
The price is ￥22,973
￥31,751 total
includes taxes & fees
Dec 20 - Dec 21
Riverside Inn Hannibal
Indoor pool, sun loungers
Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
2.5 star property
Hannibal
7.6 out of 10, Good, (659)
Steps from Hannibal attractions, this welcoming hotel offers an indoor pool and 24-hour fitness center. Guests consistently praise the complimentary breakfast, helpful staff, and convenient location near Sodalis Nature Preserve. Free WiFi and parking complete your stay.
"Below average facility. Needs some upgrades and could use a good cleaning. Staff was helpful."
United States
JACQUI
The price is ￥12,582
￥14,918 total
includes taxes & fees
Dec 28 - Dec 29
Comfort Inn & Suites - Hannibal
Deluxe Room | Down comforters, blackout drapes, iron/ironing board, free WiFi
Lighthouse Inn & Suites

Lighthouse Inn & Suites

Lighthouse Inn & Suites
4.0 star property
Hannibal
8.8 out of 10, Excellent, (23)
Stylish apartments with modern amenities await at this 4-star hideaway. Just 5 minutes from the Mississippi River, explore the nearby Molly Brown Museum and Mark Twain Memorial Lighthouse. Smart TVs and luxurious hydromassage showerheads enhance your experience.
"Very nice room, close enough to walk to riverfront attractions. "
United States
Robert
The price is ￥26,310
￥30,215 total
includes taxes & fees
Dec 16 - Dec 17
Lighthouse Inn & Suites
Indoor spa tub
Stoney Creek Inn Quincy

Stoney Creek Inn Quincy

Stoney Creek Inn Quincy
2.0 star property
Quincy
8.8 out of 10, Excellent, (1008)
Enjoy a serene retreat with hot tub, indoor and outdoor pools, and a sauna for total relaxation. Just minutes from Quincy Mall and regional attractions, this hotel offers free breakfast, WiFi, and parking with friendly staff to enhance your stay.
"Always love staying here"
United States
Ashlynn
Stoney Creek Inn Quincy
Room, 2 Queen Beds, Non Smoking | Desk, laptop workspace, free WiFi, bed sheets
Days Inn by Wyndham Hannibal

Days Inn by Wyndham Hannibal

Days Inn by Wyndham Hannibal
2.0 star property
Hannibal
7.4 out of 10, Good, (215)
This Hannibal hotel offers convenient access to West Ely Park and Sodalis Nature Preserve. Wake up to complimentary continental breakfast, connect with free WiFi, and enjoy hassle-free parking during your Mississippi River adventure.
"Left before breakfast great cup of coffee"
United States
David
The price is ￥9,816
￥11,273 total
includes taxes & fees
Dec 28 - Dec 29
Days Inn by Wyndham Hannibal
Front of property
Garden House Bed and Breakfast

Garden House Bed and Breakfast

Garden House Bed and Breakfast
2.0 star property
Hannibal
8.6 out of 10, Excellent, (37)
This charming Hannibal B&B offers complimentary parking and internet access, with hiking trails nearby. Explore Big River Train Town or visit Jim's Journey, then return to relax in provided bathrobes after a day of adventure.
"Overall stay was great and the host chris is great aswell nothing bad to say about any aspect of our stay!"
United States
Josh
The price is ￥16,687
￥19,164 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Garden House Bed and Breakfast
Family Suite, Multiple Beds | Premium bedding, desk, laptop workspace, iron/ironing board
Heritage Hotel Quincy

Heritage Hotel Quincy

Heritage Hotel Quincy
2.0 star property
Quincy
8.8 out of 10, Excellent, (271)
Just a short walk from the Mississippi River, this welcoming hotel offers free WiFi, complimentary breakfast, and convenient parking. Explore nearby Villa Kathrine or catch a train from Quincy Station for regional adventures.
"Room was very clean Breakfast was satisfying "
United States
Mark
The price is ￥13,252
￥15,105 total
includes taxes & fees
Dec 29 - Dec 30
Heritage Hotel Quincy
Lobby
Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West
2.5 star property
Hannibal
8.0 out of 10, Very Good, (1011)
Set near Hospital Park, this welcoming hotel offers a fitness center and terrace for active travelers. Wake up to free breakfast before exploring Mark Twain's hometown. The attentive staff receives high praise from guests who appreciate the convenient location.
"Very nice place to stay during a snow storm. "
United States
Teresa
The price is ￥12,256
￥14,199 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Quality Inn & Suites Hannibal West
Bar (on property)
Oak Hill Inn & Suites

Oak Hill Inn & Suites

Oak Hill Inn & Suites
2.5 star property
Canton
9.2 out of 10, Wonderful, (866)
"Great service & room .... highly recommend "
United States
Chad
The price is ￥16,405
￥18,699 total
includes taxes & fees
Dec 16 - Dec 17
Oak Hill Inn & Suites
Lobby sitting area
Motel 6 Hannibal, MO

Motel 6 Hannibal, MO

Motel 6 Hannibal, MO
2.0 star property
Hannibal
7.4 out of 10, Good, (1003)
"Very clean rooms and staff is very friendly "
United States
Sherrie
The price is ￥9,035
￥10,377 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Motel 6 Hannibal, MO
Indoor pool, seasonal outdoor pool, pool umbrellas, sun loungers
Best Western On The River

Best Western On The River

Best Western On The River
2.5 star property
Hannibal
8.6 out of 10, Excellent, (1003)
Peaceful riverside retreat just a 5-minute walk from Mississippi River and historic downtown Hannibal. Free breakfast energizes before exploring Mark Twain attractions nearby. Indoor and seasonal outdoor pools, hot tub, and fitness center enhance your relaxing stay.
"Great stay! Clean and cozy!!"
United States
Courtney
The price is ￥15,112
￥17,356 total
includes taxes & fees
Dec 17 - Dec 18
Best Western On The River
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Palmyra attractions

Murphy Island

Commune with nature and explore the great outdoors at Murphy Island during your travels in Palmyra. Take in the museums while you're in the area.
See properties

Flower City Park

Explore the great outdoors at Flower City Park, a lovely green space in Palmyra. Take in the museums while you're in the area.
See properties

Learn more about Palmyra

Escape to Palmyra! Enjoy its coffee and museums.

See all hotels in Palmyra
Bridge over Mississippi River, New Orleans in background

Top Palmyra Hotel Reviews

Microtel Inn & Suites by Wyndham Quincy Downtown/River Area

Microtel Inn & Suites by Wyndham Quincy Downtown/River Area

10/10 Excellent
"Easy check in"
Rickayla 2-night trip
Posted 2 days ago
Microtel Inn & Suites by Wyndham Quincy Downtown/River Area

More cheap stays in Palmyra

Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West

120 Lindsey Drive Hannibal MO
The price is ￥12,256 per night from Jan 4 to Jan 5
￥12,256
￥14,199 total
Jan 4 - Jan 5, 2026
includes taxes & fees
8/10 Very Good! (1,007 reviews)

Frequently asked questions

Where is the best place to stay in Palmyra?
Located 13.3 mi (21.4 km) from the heart of Palmyra, Stoney Creek Inn Quincy is a top choice for your stay based on our traveler data. Two other options for your visit to the area are Quality Inn & Suites Hannibal West and Sleep Inn & Suites Hannibal West. See all available top hotels, or vacation rentals in Palmyra.
What are some of the best vacation rentals in Palmyra?
Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi: Visitors like this Palmyra vacation home rental. It offers a patio, a garden, and air-conditioning to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. You and your friends and family can relax into your vacation with amenities like a selection of games. See all vacation rentals in Palmyra.
If I need to cancel my hotel reservation in Palmyra, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable if cancelled prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you have a non-refundable reservation, you may still be able to cancel and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Palmyra.
Where can I learn more about changing or cancelling my trip to Palmyra?
For more information about changing or cancelling your trip to Palmyra, head over to our customer service page.
How is it to stay in Palmyra?
Visitors can enjoy all that Palmyra has to offer including the coffeehouses, restaurants, and museums. This city also attracts tourists with its welcoming locals. In Palmyra, there are 4 hotels and other accommodations to choose from. Find out more about Palmyra.
What should I see while I'm in Palmyra?
Favorite places to visit include Mississippi River, Gardner House Museum, and Dr. J.W. Well Nature Park. A couple of additional sights to add to your agenda are Flower City Park and Bay Island. Check out what more to see and do in Expedia's Palmyra guide.
What's the seasonal weather like in Palmyra?
The hottest months are usually July and August with an average temp of 74°F, while the coldest months are January and February with an average of 34°F. Average annual precipitation for Palmyra is 48 inches.

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