Find hotels in Louisiana, MO from ￥10,375

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Dec 9 - Dec 10
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Dec 10 - Dec 11
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Dec 12 - Dec 14
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Our top choices for Louisiana hotels

Balcony
River's Edge Motel

River's Edge Motel

2.0 star property
Louisiana
9.0 out of 10, Wonderful, (355)
"Excellent stay !!! Quite "
United States
Bradley
The price is ￥12,463
￥14,150 total
includes taxes & fees
Dec 22 - Dec 23
River's Edge Motel
Interior
The Eagles Nest Inn

The Eagles Nest Inn

3.0 star property
Louisiana
9.4 out of 10, Exceptional, (19)
"The room was great. Large and attractive!! Nice bathroom. Had all the convenience you need from TV to mini frig. "
United States
Judith
The price is ￥14,897
￥16,913 total
includes taxes & fees
Dec 11 - Dec 12
The Eagles Nest Inn
Lobby
Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West

2.5 star property
Hannibal
8.0 out of 10, Very Good, (1006)
"Very nice place to stay during a snow storm. "
United States
Teresa
The price is ￥12,456
￥14,431 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Quality Inn & Suites Hannibal West
Indoor pool, seasonal outdoor pool, pool umbrellas, sun loungers
Best Western On The River

Best Western On The River

2.5 star property
Hannibal
8.6 out of 10, Excellent, (1000)
"Great stay! Clean and cozy!!"
United States
Courtney
The price is ￥15,733
￥18,070 total
includes taxes & fees
Dec 11 - Dec 12
Best Western On The River
Exterior
Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West

2.5 star property
Hannibal
9.6 out of 10, Exceptional, (1001)
"Great area"
United States
kelvin
The price is ￥15,758
￥18,256 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Sleep Inn & Suites Hannibal West
Indoor pool, sun loungers
Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal

2.5 star property
Hannibal
7.6 out of 10, Good, (659)
"Below average facility. Needs some upgrades and could use a good cleaning. Staff was helpful."
United States
JACQUI
The price is ￥12,580
￥14,915 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Comfort Inn & Suites - Hannibal
Desk, laptop workspace, iron/ironing board, free WiFi
Baymont by Wyndham Hannibal

Baymont by Wyndham Hannibal

2.5 star property
Hannibal
6.4 out of 10, (735)
" There actually was a pool & there actually was a hot breakfast. It didn't just say there was & not have what was listed. One of the best we've been to as of late. Would stay again if in the area. "
United States
Thomas
The price is ￥10,126
￥11,707 total
includes taxes & fees
Dec 11 - Dec 12
Baymont by Wyndham Hannibal
Lobby sitting area
Motel 6 Hannibal, MO

Motel 6 Hannibal, MO

2.0 star property
Hannibal
7.4 out of 10, Good, (1000)
"Very clean rooms and staff is very friendly "
United States
Sherrie
The price is ￥9,034
￥10,375 total
includes taxes & fees
Dec 19 - Dec 20
Motel 6 Hannibal, MO
Room, 2 Queen Beds, Non Smoking | Desk, laptop workspace, free WiFi, bed sheets
Days Inn by Wyndham Hannibal

Days Inn by Wyndham Hannibal

2.0 star property
Hannibal
7.4 out of 10, Good, (215)
"Left before breakfast great cup of coffee"
United States
David
The price is ￥10,095
￥11,594 total
includes taxes & fees
Dec 28 - Dec 29
Days Inn by Wyndham Hannibal
Exterior
Super 8 by Wyndham Hannibal

Super 8 by Wyndham Hannibal

2.0 star property
Hannibal
7.2 out of 10, Good, (1000)
"My stay was excellent staff very friendly and breakfast was always great "
United States
Sherrie
The price is ￥10,594
￥12,167 total
includes taxes & fees
Dec 12 - Dec 13
Super 8 by Wyndham Hannibal
Free daily on-the-go breakfast
Rodeway Inn Pittsfield

Rodeway Inn Pittsfield

2.0 star property
Pittsfield
6.8 out of 10, (125)
"Air conditioning | Pet-friendly | Clean room | Staf"
United States
Anonymous traveler
The price is ￥9,590
￥10,548 total
includes taxes & fees
Dec 14 - Dec 15
Rodeway Inn Pittsfield
Breakfast meal
William Watson Hotel

William Watson Hotel

3.0 star property
Pittsfield
9.2 out of 10, Wonderful, (346)
"Great location, restaurant downstairs, friendly staff, microwaves and refrigerator in room, historic significance "
United States
Druann
The price is ￥12,977
￥14,272 total
includes taxes & fees
Dec 19 - Dec 20
William Watson Hotel
Deluxe Room | Down comforters, blackout drapes, iron/ironing board, free WiFi
Lighthouse Inn & Suites

Lighthouse Inn & Suites

4.0 star property
Hannibal
8.8 out of 10, Excellent, (23)
"Very nice room, close enough to walk to riverfront attractions. "
United States
Robert
The price is ￥26,306
￥30,212 total
includes taxes & fees
Dec 11 - Dec 12
Lighthouse Inn & Suites
Lobby sitting area
Howard Johnson BY Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal

2.0 star property
Hannibal
7.2 out of 10, Good, (152)
"The gentleman at the front desk was extremely nice and did everything to make my stay wonderful. The breakfast was awesome. The pool was sooo nice. The exercise room was great. I cannot say anything bad about this hotel. This was the first time I stayed here and I will be coming back every three months.!"
United States
Shawn
The price is ￥9,028
￥10,439 total
includes taxes & fees
Dec 12 - Dec 13
Howard Johnson BY Wyndham Hannibal
Front of property
Garden House Bed and Breakfast

Garden House Bed and Breakfast

2.0 star property
Hannibal
8.6 out of 10, Excellent, (36)
"Overall stay was great and the host chris is great aswell nothing bad to say about any aspect of our stay!"
United States
Josh
The price is ￥16,981
￥19,502 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Garden House Bed and Breakfast
Lobby sitting area
Green Acres Hotel

Green Acres Hotel

2.5 star property
Pittsfield
8.6 out of 10, Excellent, (141)
"Great stay"
United States
Jeramy
The price is ￥16,685
￥18,349 total
includes taxes & fees
Dec 11 - Dec 12
Green Acres Hotel
Comfort Room | Premium bedding, desk, iron/ironing board, free cribs/infant beds
Monroe Street Suites

Monroe Street Suites

2.5 star property
Pittsfield
9.6 out of 10, Exceptional, (57)
"We had a great stay and would recommend others to stay here!"
United States
Brady
The price is ￥13,437
￥14,778 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Monroe Street Suites
55-inch TV with cable channels, Netflix, Hulu
Riverside Inn Hannibal

Riverside Inn Hannibal

2.5 star property
Hannibal
9.4 out of 10, Exceptional, (164)
"Great place to stay!"
United States
Sandy
The price is ￥22,970
￥31,748 total
includes taxes & fees
Dec 20 - Dec 21
Riverside Inn Hannibal
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Louisiana

Like rivers? Get away to relaxing Louisiana!

See all hotels in Louisiana
Open swing span of Louisiana railroad bridge across the upper Mississippi near the town of Louisiana in Missouri

Top Louisiana Hotel Reviews

Best Western On The River

Best Western On The River

10/10 Excellent
"Clean and well-maintained. Friendly staff. "
Theresa 2-night trip
Posted 7 days ago
Best Western On The River

More cheap stays in Louisiana

Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal

4000 Market St Hannibal MO
The price is ￥12,580 per night from Jan 2 to Jan 3
￥12,580
￥14,915 total
Jan 2 - Jan 3, 2026
includes taxes & fees
7.6/10 Good! (659 reviews)

Frequently asked questions

Where is the best place to stay in Louisiana?
The Eagles Nest Inn is a favorite property for Expedia customers. This inn is a short 3-minute walk from Mississippi River, and it offers a restaurant and free parking. Another top choice for your stay based on reviews is River's Edge Motel. See all available top hotels, or vacation rentals in Louisiana.
What are some of the best vacation rentals in Louisiana?
The Yellow Rose Historic Home: Visitors like this Louisiana vacation home rental. It offers a selection of games, a barbecue grill, and air-conditioning to help you feel perfectly comfortable in your new surroundings. It has 5 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. See all vacation rentals in Louisiana.
If I need to cancel my hotel reservation in Louisiana, will I receive a refund?
Yes! The majority of hotel reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, it might still be possible to cancel it and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Louisiana.
Where can I learn more about changing or cancelling my trip to Louisiana?
To access more information about picking new dates or cancelling your trip to Louisiana, go to https://www.expedia.com/service/.
What's the best hotel for a couple visiting Louisiana?
Come see what our Historical town has to offer! is a favorite B&B for couples, and features in-room kitchenettes and private patios. See all romantic hotels in Louisiana.
What's the best pet-friendly hotel in Louisiana?
River's Edge Motel is a top pet-friendly option for your stay. See more pet-friendly hotel accommodations in Louisiana.
What are some hotels with pools in Louisiana?
Quality Inn & Suites Hannibal West: Features a snack bar/deli, an indoor pool, and buffet. Sleep Inn & Suites Hannibal West and Best Western On The River are two additional hotels with an onsite pool. View all hotels with pools in Louisiana.
What's the best accommodation near Lambert-St. Louis International Airport (STL)?
Marriott St. Louis Airport is a popular 3.5-star hotel featuring a restaurant and an outdoor pool. It's located a short 0.3 mi (0.5 km) from Lambert-St. Louis Intl. Airport. Other good choices within close proximity to the airport include Pear Tree Inn Airport - St. Louis - St. Ann, MO and Drury Inn & Suites St. Louis Airport.
What is staying in Louisiana like?
Visitors to Louisiana are sure to enjoy the riverfront. This city also attracts tourists with its welcoming and relaxing setting. In Louisiana, there are 5 hotels and other accommodations to choose from. Find out more about Louisiana.
What should I do while I'm visiting Louisiana?
A favorite place to visit is Mississippi River. You'll also find Clarksville Riverfront Park and Clarksville State Game Refuge in the area. Check out what more to see and do in Expedia's Louisiana guide.
What's the seasonal weather like in Louisiana?
The hottest months are usually July and August with an average temp of 74°F, while the coldest months are January and February with an average of 35°F. Average annual precipitation for Louisiana is 49 inches.

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