A river with a large, rusted metal bridge and a smaller bridge in the background.

Find hotels in Louisiana, MO from ￥9,487

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
Nov 6 - Nov 8
In two weeks
Nov 13 - Nov 15

Filter by

Property class

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Louisiana hotels

A gazebo with a table and benches, surrounded by trees and a body of water.

1. River's Edge Motel

River's Edge Motel
2.0 star property
Louisiana
8.8 out of 10, Excellent, (395 reviews)
"Nice location."
United States
Jeff
The price is ￥13,865
￥15,743 total
includes taxes & fees
Nov 1 - Nov 2
River's Edge Motel
A restaurant with a bar area, wooden flooring, checkered tablecloths, and a brick wall.

2. The Eagles Nest Inn

The Eagles Nest Inn
3.0 star property
Louisiana
9.6 out of 10, Exceptional, (28 reviews)
"Cutest place to stay in Louisiana Missouri"
United States
Kimberly
The price is ￥16,208
￥18,403 total
includes taxes & fees
Nov 10 - Nov 11
The Eagles Nest Inn
A cozy living area with a leather sofa, a wooden coffee table, and a patterned armchair. A brick wall and wooden shelves with various items are visible.

3. William Watson Hotel

William Watson Hotel
3.0 star property
Pittsfield
9.4 out of 10, Exceptional, (381 reviews)
"My room was immaculate and comfortable! The staff was super sweet!! 100/10! Will definitely stay again!"
United States
Mary
The price is ￥13,393
￥14,729 total
includes taxes & fees
Nov 2 - Nov 3
William Watson Hotel
A hotel room with a large bed, a separate bathroom with a bathtub, and a desk with a chair.

4. Best Western On The River

Best Western On The River
2.5 star property
Hannibal
8.8 out of 10, Excellent, (1,005 reviews)
"fun town to stay and visit"
United States
Wei
The price is ￥17,330
￥19,990 total
includes taxes & fees
Nov 1 - Nov 2
Best Western On The River
Front of property

5. Monroe Street Suites

Monroe Street Suites
2.5 star property
Pittsfield
9.8 out of 10, Exceptional, (72 reviews)
"Best place Ive stayed period. 100 percent recommend"
United States
Isidro
The price is ￥17,410
￥19,148 total
includes taxes & fees
Nov 3 - Nov 4
Monroe Street Suites
A hallway with wooden doors leading to a dining area with a table and chairs.

6. Green Acres Hotel

Green Acres Hotel
2.5 star property
Pittsfield
8.8 out of 10, Excellent, (153 reviews)
"Enjoyed our stay at Green Acres! When we return we will definitely stay there again"
United States
Kimberly
The price is ￥23,242
￥25,561 total
includes taxes & fees
Nov 9 - Nov 10
Green Acres Hotel
A Sleep Inn & Suites building with a covered entrance, stone facade, and a flag.

7. Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
2.5 star property
Hannibal
9.6 out of 10, Exceptional, (1,001 reviews)
"Great stay- within walking distance of good restaurant and coffee shop. Breakfast included hot items with adequate seating."
United States
ELAINE
The price is ￥16,560
￥19,267 total
includes taxes & fees
Nov 25 - Nov 26
Sleep Inn & Suites Hannibal West
A hotel room with a bed, a sofa, a desk, and a lamp.

8. Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
2.5 star property
Hannibal
7.6 out of 10, Good, (771 reviews)
"Front desk helpful Clean rooms Great breakfast and lady fixing our breakfast was helpful and kept plenty of food ready for all"
United States
Jerry
The price is ￥12,170
￥14,511 total
includes taxes & fees
Nov 25 - Nov 26
Comfort Inn & Suites - Hannibal
A bakery display with various baked goods and packaged snacks.

9. Rodeway Inn Pittsfield

Rodeway Inn Pittsfield
2.0 star property
Pittsfield
6.8 out of 10, (145 reviews)
"We stay everytime we are in town"
United States
Stephanie
The price is ￥10,848
￥11,930 total
includes taxes & fees
Nov 30 - Dec 1
Rodeway Inn Pittsfield
An indoor swimming pool with a tiled floor, a rock wall, and a palm tree.

10. Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West
2.5 star property
Hannibal
8.0 out of 10, Very good, (1,000 reviews)
"Our go to hotel for years when we visit Hannibal."
United States
Gayle
The price is ￥12,476
￥14,515 total
includes taxes & fees
Nov 23 - Nov 24
Quality Inn & Suites Hannibal West
A modern hotel with a flat roof, multiple windows, and a sign indicating it is a Super 8 hotel.

11. Super 8 by Wyndham Hannibal

Super 8 by Wyndham Hannibal
2.0 star property
Hannibal
7.2 out of 10, Good, (1,001 reviews)
"Clean, safe hotel and friendly staff"
United States
Julie
The price is ￥9,729
￥11,222 total
includes taxes & fees
Dec 1 - Dec 2
Super 8 by Wyndham Hannibal
A spacious lobby with a black leather sofa, a matching armchair, a coffee table, and a chandelier.

12. Motel 6 Hannibal, MO

Motel 6 Hannibal, MO
2.0 star property
Hannibal
7.4 out of 10, Good, (1,000 reviews)
"Excellent place to stay"
United States
Jared
The price is ￥9,137
￥10,539 total
includes taxes & fees
Nov 3 - Nov 4
Motel 6 Hannibal, MO
An indoor swimming pool with a tiled ceiling, multiple levels with windows, and seating areas around the pool.

13. Baymont by Wyndham Hannibal

Baymont by Wyndham Hannibal
2.5 star property
Hannibal
6.4 out of 10, (828 reviews)
"If you are looking for a good budget Hotel this place is it. Friendly helpful staff. The room was spacious and the TV was big. Breakfast was decent. Scrambled eggs, biscuits and gravy, waffles and pastries."
United States
John
The price is ￥8,169
￥9,487 total
includes taxes & fees
Dec 1 - Dec 2
Baymont by Wyndham Hannibal
A hotel room with two beds, a wooden headboard, a nightstand with a phone, and a wall-mounted lamp.

14. Days Inn by Wyndham Hannibal

Days Inn by Wyndham Hannibal
2.0 star property
Hannibal
7.4 out of 10, Good, (294 reviews)
"Pretty good place to stay at with a great price !!"
United States
Christian
The price is ￥8,823
￥10,178 total
includes taxes & fees
Nov 4 - Nov 5
Days Inn by Wyndham Hannibal
A hotel room with a large bed, two bedside lamps, a modern bathroom, and a vibrant abstract painting on the wall.

15. Lighthouse Inn & Suites

Lighthouse Inn & Suites
4.0 star property
Hannibal
8.8 out of 10, Excellent, (47 reviews)
"The room was very clean. It had a hot tub in it and it was also very clean and worked properly. We enjoyed our stay there."
United States
Connie
The price is ￥25,101
￥34,409 total
includes taxes & fees
Nov 1 - Nov 2
Lighthouse Inn & Suites
A room with a beige leather sofa, a wooden coffee table, a floor lamp, and a patterned carpet.

16. Riverside Inn Hannibal

Riverside Inn Hannibal
2.5 star property
Hannibal
9.6 out of 10, Exceptional, (204 reviews)
"Very nice room and great view of the river. Very comfortable bed and very nice shower. Walking distance to so many restaurants and shops. We enjoyed our stay very much!"
United States
Christina
The price is ￥23,895
￥33,017 total
includes taxes & fees
Nov 1 - Nov 2
Riverside Inn Hannibal
A large indoor swimming pool with multiple levels of balconies, surrounded by seating areas and potted plants.

17. Howard Johnson BY Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal
2.0 star property
Hannibal
7.4 out of 10, Good, (187 reviews)
"Great price! Nice comfortable clean room"
United States
Debbie
The price is ￥9,075
￥10,538 total
includes taxes & fees
Dec 1 - Dec 2
Howard Johnson BY Wyndham Hannibal
A wooden staircase with a handrail, a small table with a lamp, and a chair in a room with a door and windows.

18. Garden House Bed and Breakfast

Garden House Bed and Breakfast
3.0 star property
Hannibal
8.4 out of 10, Very good, (57 reviews)
"Beautiful Queen Ann B&B, was reasonably priced and within walking distance to the river and down town Hannibal attractions."
United States
Debbie
The price is ￥15,113
￥17,433 total
includes taxes & fees
Dec 1 - Dec 2
Garden House Bed and Breakfast
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Learn more about Louisiana

Like rivers? Get away to relaxing Louisiana!

See all hotels in Louisiana
A river with a large, rusted metal bridge and a smaller bridge in the background.

Top Louisiana Hotel Reviews

Best Western On The River

Best Western On The River

10/10 Excellent
"We had a great river view from the 2nd floor. The location is close to many historical locations and the downtown. You can walk to some really good restaurants. I hope to stay here again."
Marjorie 1-night trip
Posted 12 hours ago
Best Western On The River

More cheap stays in Louisiana

Baymont by Wyndham Hannibal

Baymont by Wyndham Hannibal

4141 Market St Hannibal MO
The price is ￥8,169 per night from Dec 1 to Dec 2
￥8,169
￥9,487 total
Dec 1 - Dec 2
includes taxes & fees

Frequently asked questions

Where is the best place to stay in Louisiana?
Based on our traveler data, The Eagles Nest Inn is one of the top choices for your stay. This inn is a short 3-minute walk from Mississippi River, and it offers a restaurant and free parking. River's Edge Motel is another good option for your trip. See all available top hotels, or vacation rentals in Louisiana.
What are some of the best vacation rentals in Louisiana?
The Yellow Rose Historic Home: Visitors like this Louisiana vacation home rental. It offers a selection of games, a barbecue grill, and air-conditioning to help you feel perfectly comfortable in your new surroundings. It has 5 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. See all vacation rentals in Louisiana.
If I need to cancel my hotel reservation in Louisiana, will I receive a refund?
Yes! The majority of hotel reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, it might still be possible to cancel it and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Louisiana.
Where can I learn more about changing or cancelling my trip to Louisiana?
To access more information about picking new dates or cancelling your trip to Louisiana, go to https://www.expedia.com/service/.
What's the best hotel for a couple visiting Louisiana?
Come see what our Historical town has to offer! is a favorite B&B for couples, and features in-room kitchenettes and private patios. See all romantic hotels in Louisiana.
What's the best pet-friendly hotel in Louisiana?
River's Edge Motel is a top pet-friendly option for your stay. See more pet-friendly hotel accommodations in Louisiana.
What are some hotels with pools in Louisiana?
Quality Inn & Suites Hannibal West: Features a snack bar/deli, an indoor pool, and buffet. Best Western On The River and Comfort Inn & Suites - Hannibal are two additional hotels with an onsite pool. View all hotels with pools in Louisiana.
What's the best accommodation near Lambert-St. Louis International Airport (STL)?
Marriott St. Louis Airport is a popular 3.5-star hotel featuring a restaurant and an outdoor pool. It's located a short 0.3 mi (0.5 km) from Lambert-St. Louis Intl. Airport. Other good choices within close proximity to the airport include Pear Tree Inn Airport - St. Louis - St. Ann, MO and Drury Inn & Suites St. Louis Airport.
What is staying in Louisiana like?
Visitors to Louisiana are sure to enjoy the riverfront. This city also attracts tourists with its welcoming and relaxing setting. In Louisiana, there are 5 hotels and other accommodations to choose from. Find out more about Louisiana.
What should I do while I'm visiting Louisiana?
A favorite place to visit is Mississippi River. You'll also find Clarksville State Game Refuge and Clarksville Riverfront Park in the area. Check out what more to see and do in Expedia's Louisiana guide.
What's the seasonal weather like in Louisiana?
The hottest months are usually July and August with an average temp of 74°F, while the coldest months are January and February with an average of 35°F. Average annual precipitation for Louisiana is 49 inches.

Explore a world of travel with Expedia