The Best Hotels Closest to North Mississippi Medical Center in Tupelo for 2026

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Our top choices for North Mississippi Medical Center hotels

A modern lounge area with a neon sign, large windows, and a pool table.

A modern interior with a brick wall, large windows, and a wooden floor.

A modern living room with a blue sofa, a round coffee table, and a cityscape view through large windows.

A modern hotel with a brick facade, large windows, and a covered outdoor seating area.

1. Hotel Tupelo, a Wyndham Hotel

2.2 km from North Mississippi Medical Center

Doug

￥25,082

￥27,403 total

includes taxes & fees

Sep 27 - Sep 28

A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

A laundry area with two Whirlpool front-loading washers, a Tide detergent dispenser, and a sign indicating it's for guest use only.

A Holiday Inn & Suites hotel with a modern design, featuring a covered entrance and a parking lot.

2. Holiday Inn Hotel & Suites Tupelo North by IHG

3 km from North Mississippi Medical Center

Larry

￥18,579

￥20,297 total

includes taxes & fees

Oct 4 - Oct 5

A hotel room with a conference table, chairs, a bed, a TV, and a door leading to another room.

A vending area with various snack options and a beverage cooler.

A multi-story hotel with a covered outdoor seating area, a paved walkway, and a landscaped garden.

A hotel room with a dark wood dining table, a brown leather chair, a microwave, a refrigerator, and a corkboard on the wall.

3. Candlewood Suites Tupelo North by IHG

3 km from North Mississippi Medical Center

Rhonda

￥17,949

￥19,609 total

includes taxes & fees

Sep 27 - Sep 28

A spacious lobby with a central reception desk, large potted plants, and a modern chandelier.

A modern lounge area with wicker furniture, a large wooden pendant light, and a colorful striped carpet.

A hotel lobby with a seating area, large windows, and a fireplace.

A spacious living room with a fireplace, comfortable seating, and a coffee table with fruit.

4. Hilton Garden Inn Tupelo

2.3 km from North Mississippi Medical Center

Rhonda

￥16,655

￥18,196 total

includes taxes & fees

Oct 1 - Oct 2

A reception area with a wooden desk, a reception counter, a waiting area with brown upholstered chairs, a large window with a view of buildings, and a door marked "EXIT".

A hotel room with a green sofa, a desk with a computer and lamp, a small refrigerator, and a round mirror on the wall.

A hotel room with a desk, chair, television, minibar, and a bed.

A compact kitchen with wooden cabinets, a microwave, a toaster, and a juice dispenser. There are two red chairs and a wooden table.

5. SureStay Hotel by Best Western Tupelo North

2.8 km from North Mississippi Medical Center

Melissa

￥9,212

￥10,065 total

includes taxes & fees

Oct 4 - Oct 5

A hotel entrance with a covered waiting area, a bench, and a car parking lot.

A hotel room with two beds, each with a patterned bedspread, a bedside table with a clock, and a wall-mounted light fixture.

A gym with exercise equipment, a fan, and a door leading to another room.

A staircase with carpeted steps and a black handrail, leading to a hallway with wooden walls and a tiled floor.

6. Studio 6 Suites Tupelo, MS - North

3.1 km from North Mississippi Medical Center

David

￥9,378

￥11,033 total

includes taxes & fees

Sep 26 - Sep 27

A hotel room with a bed, a desk with a flat-screen TV, a microwave, a sink, and a mirror.

A modern kitchen with a built-in stove, a coffee machine, and a refrigerator.

A hotel lobby with a red chair, a table with stacked items, and a large window offering a view of the parking lot and trees.

A reception area with a counter, a red chair, a small table with a lamp, and a view of the parking lot outside.

7. Motel 6 Tupelo, MS - Downtown

3 km from North Mississippi Medical Center

David

￥9,919

￥10,837 total

includes taxes & fees

Sep 27 - Sep 28

A room with a green wall, a decorative wall piece, an air conditioner, and a welcome sign.

A hotel room with two beds, a nightstand, a lamp, and two framed pictures on the wall.

A reception desk with a sign detailing room rules, a coat rack, a chair, and a small table with items on it.

8. Scottish Inns

2 km from North Mississippi Medical Center

David

￥9,447

￥10,321 total

includes taxes & fees

Sep 27 - Sep 28

A hotel room with two beds, a desk, a chair, a television, and a window.

A hotel room with a blue sofa, a desk with a chair, a coffee table, and a kitchenette in the background.

A coffee station with two coffee machines, a coffee press, and various coffee-related items on a counter.

A hotel lobby with a chandelier, leather chairs, a fireplace, and a television.

9. Holiday Inn Express Hotel & Suites Tupelo by IHG

4.1 km from North Mississippi Medical Center

Fernando

￥15,902

￥17,374 total

includes taxes & fees

Oct 18 - Oct 19

An outdoor seating area with chairs and a fire pit, a brick building, and a clear sky.

An indoor swimming pool with clear blue water, surrounded by yellow and blue chairs, and a water fountain on the left.

A modern breakfast area with a counter, seating, and various food items.

A gym with exercise equipment, a spinning bike, and a bench.

10. Home2 Suites By Hilton Tupelo, Ms

4.3 km from North Mississippi Medical Center

Michael

￥18,129

￥19,806 total

includes taxes & fees

Oct 4 - Oct 5

A modern hotel lobby with a reception desk, seating area, and unique lighting fixtures.

A modern hotel building with a prominent 'tru by Hilton' sign, multiple windows, and a well-lit entrance.

A snack display in a store with various brands and types of snacks.

A breakfast buffet area with various food items and a coffee machine.

11. Tru By Hilton Tupelo

4.3 km from North Mississippi Medical Center

Justin

￥15,444

￥16,872 total

includes taxes & fees

Oct 25 - Oct 26

A spacious hotel lobby with a dining area, sofas, and a TV mounted on the wall.

A hotel room with a wooden desk, a blue sofa, a small ottoman, a chair, a lamp, and framed pictures on the wall.

A hotel room with a bed, a desk, a chair, a sofa, a TV, and a lamp.

A reception area with a stone wall, wooden reception desk, and a vending machine.

12. Comfort Suites North Tupelo

6.8 km from North Mississippi Medical Center

Peggy

￥13,915

￥15,202 total

includes taxes & fees

Oct 21 - Oct 22

A large indoor swimming pool with multiple seating areas and large windows.

A hotel with a modern design, featuring a covered entrance and a parking lot.

A reception desk with a "Welcome to Hampton" sign, a "Hilton Honors" plaque, and a view of a building through a window.

13. Hampton Inn & Suites Tupelo/Barnes Crossing

6.8 km from North Mississippi Medical Center

Tina

￥21,583

￥23,580 total

includes taxes & fees

Sep 27 - Sep 28

A hotel lobby with a reception desk, seating area with ottomans, and a patterned carpet.

A multi-story hotel with a covered entrance and a parking area.

A kitchen with granite countertops, wooden cabinets, and a tiled backsplash.

An indoor swimming pool with a clear view of the pool area, including the poolside seating and the pool's edge.

14. Best Western Plus Tupelo Inn & Suites

6.3 km from North Mississippi Medical Center

Robert

￥16,595

￥18,129 total

includes taxes & fees

Oct 1 - Oct 2

A modern, well-lit office space with multiple tables and chairs, a reception area, and large windows offering a view of greenery.

A hotel with a modern facade, a covered entrance, and a well-maintained lawn.

A modern building with large windows and a patio area with white metal furniture.

A hotel room with a bed, a sofa, a desk, and a lamp.

15. Spark by Hilton Tupelo

6.3 km from North Mississippi Medical Center

￥15,493

￥16,926 total

includes taxes & fees

Oct 1 - Oct 2

A multi-story hotel with a prominent entrance, a covered patio area, and a landscaped courtyard.

A lobby with patterned sofas, a coffee machine, a television, and a snack vending machine.

A spacious lobby with patterned seating, a stone accent wall, a flat-screen TV, and a snack bar.

A rectangular swimming pool with a tiled deck, surrounded by a brick wall and metal fencing.

16. La Quinta Inn & Suites by Wyndham Tupelo

3.6 km from North Mississippi Medical Center

Annette

￥15,436

￥16,863 total

includes taxes & fees

Sep 27 - Sep 28

A Fairfield Inn & Suites Marriott hotel with a modern facade, a covered entrance, and a parking area.

An outdoor patio with round tables and chairs, potted plants, and a building with a modern design.

A hotel lobby with a central bar area, seating arrangements, and a buffet with pastries.

17. Fairfield Inn & Suites by Marriott Tupelo

7.2 km from North Mississippi Medical Center

Kelly

￥16,239

￥17,741 total

includes taxes & fees

Oct 25 - Oct 26

A hotel room with a bed, a TV mounted on the wall, a desk with a chair, a small refrigerator, and a bedside table.

A Red Roof Inn sign on a stone wall, a vase with flowers on a table, and two leather chairs.

A coffee station with a coffee machine, disposable cups, and a coffee dispenser.

18. Red Roof Inn Tupelo

3.6 km from North Mississippi Medical Center

Harley

￥9,872

￥10,786 total

includes taxes & fees

Oct 1 - Oct 2

A Courtyard Marriott hotel entrance at night with a well-lit facade, a covered parking area, and a landscaped garden.

A hotel room with a bed, a sofa, a desk, and a TV.

A modern lobby with a reception desk, seating area, and a large abstract mural.

A modern hotel lobby with round tables, comfortable seating, a bar area, and a TV screen displaying golf.

19. Courtyard By Marriott Tupelo

3.9 km from North Mississippi Medical Center

Keyunna

￥18,280

￥19,971 total

includes taxes & fees

Oct 4 - Oct 5

A reception area with a stone wall, a painting of autumn trees, and a potted plant.

A bathroom with a toilet, grab bars, a sink, and a mirror.

A hotel room with a bed, two bedside tables with lamps, a sofa, and a small table.

A hotel with a red roof and a sign indicating it is an Americor Best Value Inn.

20. Americas Best Value Inn Tupelo Barnes Crossing

7.9 km from North Mississippi Medical Center

Lauren

￥11,022

￥12,747 total

includes taxes & fees

Sep 27 - Sep 28

View all properties

Compare popular hotels close to North Mississippi Medical Center

Property	Star rating	Guest rating
Hotel Tupelo, a Wyndham Hotel	9.6 Exceptional 699 reviews	View
Holiday Inn Hotel & Suites Tupelo North by IHG	9.2 Wonderful 1,000 reviews	View
Candlewood Suites Tupelo North by IHG	8.6 Excellent 463 reviews	View
Hilton Garden Inn Tupelo	8.0 Very good 1,002 reviews	View
SureStay Hotel by Best Western Tupelo North	7.4 Good 255 reviews	View

Top North Mississippi Medical Center Hotel Reviews

Hilton Garden Inn Tupelo

8/10 Good

"Nice place with friendly and welcoming staff. Only complaint was our room remained warmer than I like at night despite turning the thermostat down, it still stayed around the same temperature."

Red Roof Inn Tupelo

8/10 Good

"na"

Spacious Historic Downtown home that sleeps up to 10!

10/10 Excellent

"The house was the perfect size for 3 adults and a dog. It's in a nice neighborhood and was very quiet."

Comfort Inn Tupelo Central

8/10 Good

"The stay was good, the room was awful. The shower door was off the track and fell on me while I was in the shower. The drawers on the dresser would not stay closed. The phone in the room didn’t work because the cord had been chewed by something."

Baymont by Wyndham Tupelo

8/10 Good

"N/A"

Holiday Inn Hotel & Suites Tupelo North by IHG

10/10 Excellent

"What a pleasant surprise. Great stay and friendly people. WHo knew a Holiday Inn would have seriously good food. Jason, the bartender was great!"

La Quinta Inn & Suites by Wyndham Tupelo

8/10 Good

"The room was clean and well prepared. The staff were very friendly and answered questions from check in to check out. We stayed at 5 different hotels on this vacation and the staff here were the most welcoming of us and our dog. Though others "welcomed" pets they were not very welcoming, but LaQuinta was different. There were some problems with breakfast equipment, but they were working to fix it."

Holiday Inn Express Hotel & Suites Tupelo by IHG

10/10 Excellent

"clean! very friendly staff! thank you"

Motel 6 Tupelo, MS - Downtown

8/10 Good

"d"

Frequently asked questions

What's the area like around North Mississippi Medical Center?

North Mississippi Medical Center is located in a welcoming area of Tupelo known for its major shopping area. If you're looking for a convenient place to stay, check out the 7 hotels and other accommodations you'll find within a mile.

What's the best hotel to stay close to North Mississippi Medical Center?

Best Western Plus Tupelo Inn & Suites is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located 3.9 mi (6.3 km) from North Mississippi Medical Center. Other good options within a few miles include Red Roof Inn Tupelo and Holiday Inn Hotel & Suites Tupelo North by IHG.

How many hotels are there near North Mississippi Medical Center?

Expedia has 7 hotels and other accommodations within a mile from North Mississippi Medical Center.

If I need to cancel the hotel reservation for my stay near North Mississippi Medical Center, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and be given a refund within 24 hours of booking. Add your dates and click on "Search", then you can filter by "fully refundable" to review the best options available near North Mississippi Medical Center.

Where can I learn more about changing or cancelling my trip in the area near North Mississippi Medical Center?

For more information about rescheduling or cancelling your stay near North Mississippi Medical Center, click here.

What can I see and do near North Mississippi Medical Center?

You'll want to browse the exhibits at Elvis Presley Center and Oren Dunn City Museum. You might spend a leisurely day outdoors at Ballard Park and Elvis Presley Lake and Campground. Stopping by Cadence Bank Arena, Rob Leake City Park Tennis Center, or Cinemark Tupelo Movies 8 is a fun way to see all the area has to offer.

Find hotels near North Mississippi Medical Center, Tupelo from ￥10,065

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Treat yourself

Be picky

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Our top choices for North Mississippi Medical Center hotels

1. Hotel Tupelo, a Wyndham Hotel

2. Holiday Inn Hotel & Suites Tupelo North by IHG

3. Candlewood Suites Tupelo North by IHG

4. Hilton Garden Inn Tupelo

5. SureStay Hotel by Best Western Tupelo North

6. Studio 6 Suites Tupelo, MS - North

7. Motel 6 Tupelo, MS - Downtown

8. Scottish Inns

9. Holiday Inn Express Hotel & Suites Tupelo by IHG

10. Home2 Suites By Hilton Tupelo, Ms

11. Tru By Hilton Tupelo

12. Comfort Suites North Tupelo

13. Hampton Inn & Suites Tupelo/Barnes Crossing

14. Best Western Plus Tupelo Inn & Suites

15. Spark by Hilton Tupelo

16. La Quinta Inn & Suites by Wyndham Tupelo

17. Fairfield Inn & Suites by Marriott Tupelo

18. Red Roof Inn Tupelo

19. Courtyard By Marriott Tupelo

20. Americas Best Value Inn Tupelo Barnes Crossing

Compare popular hotels close to North Mississippi Medical Center

Top North Mississippi Medical Center Hotel Reviews

Hilton Garden Inn Tupelo

Red Roof Inn Tupelo

Spacious Historic Downtown home that sleeps up to 10!

Comfort Inn Tupelo Central

Baymont by Wyndham Tupelo

Holiday Inn Hotel & Suites Tupelo North by IHG

La Quinta Inn & Suites by Wyndham Tupelo

Holiday Inn Express Hotel & Suites Tupelo by IHG

Motel 6 Tupelo, MS - Downtown

Frequently asked questions