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Our top choices for Mission Bay hotels

Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina
4.0 star property
Mission Bay
8.4 out of 10, Very Good, (1,598 reviews)
"Balcony view is awesome, clean room, staff at counter and restaurant service was stunning."
United States
francisco
The price is ¥24,998
¥37,052 total
includes taxes & fees
Feb 8 - Feb 9
Hyatt Regency Mission Bay Spa and Marina

Paradise Point Resort & Spa

Paradise Point Resort & Spa
4.0 star property
Mission Bay
8.8 out of 10, Excellent, (2,402 reviews)
"Clean rooms, friendly staff, and a beautiful view all around.. "
United States
Morgan
The price is ¥22,561
¥34,253 total
includes taxes & fees
Mar 1 - Mar 2
Paradise Point Resort & Spa

The Dana on Mission Bay

The Dana on Mission Bay
3.5 star property
Mission Bay
9.0 out of 10, Wonderful, (4,067 reviews)
"Great location and grounds!"
United States
Ethan
The price is ¥25,784
¥33,251 total
includes taxes & fees
Feb 22 - Feb 23
The Dana on Mission Bay

San Diego Mission Bay Resort

San Diego Mission Bay Resort
4.0 star property
Mission Bay
8.4 out of 10, Very Good, (1,342 reviews)
"Great place for our family getaway! Loved the S’mores on the beach! "
United States
Dani
The price is ¥31,287
¥44,277 total
includes taxes & fees
Feb 16 - Feb 17
San Diego Mission Bay Resort

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection
3.0 star property
8.2 km from Mission Bay
9.0 out of 10, Wonderful, (1,025 reviews)
"Clean rooms and friendly staff"
United States
Topeka
The price is ¥13,003
¥15,077 total
includes taxes & fees
Feb 8 - Feb 9
The DEXTRO Little Italy, BW Premier Collection

Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
8 km from Mission Bay
8.4 out of 10, Very Good, (6,026 reviews)
"Great place to stay"
United States
David
The price is ¥23,854
¥33,113 total
includes taxes & fees
Feb 15 - Feb 16
Wyndham San Diego Bayside

The Sofia Hotel

The Sofia Hotel
3.5 star property
8.7 km from Mission Bay
8.6 out of 10, Excellent, (1,748 reviews)
"Great hotel "
United States
Alexander
The price is ¥16,206
¥22,532 total
includes taxes & fees
Mar 8 - Mar 9
The Sofia Hotel

DoubleTree by Hilton San Diego - Del Mar

DoubleTree by Hilton San Diego - Del Mar
4.0 star property
Carmel Valley, 17.8 km from Mission Bay
8.4 out of 10, Very Good, (2,041 reviews)
"Nice hotel, staff is great."
United States
Felipe Ramirez
The price is ¥20,441
¥23,291 total
includes taxes & fees
Mar 8 - Mar 9
DoubleTree by Hilton San Diego - Del Mar

Best Western Plus Island Palms Hotel & Marina

Best Western Plus Island Palms Hotel & Marina
3.0 star property
7 km from Mission Bay
9.0 out of 10, Wonderful, (1,581 reviews)
"Great place.very clean great for family would definitely stay there again."
United States
Joseph
The price is ¥22,325
¥25,662 total
includes taxes & fees
Mar 8 - Mar 9
Best Western Plus Island Palms Hotel & Marina

Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld
3.0 star property
2.6 km from Mission Bay
7.4 out of 10, Good, (4,170 reviews)
"Good location friendly staff"
United States
Anya
The price is ¥13,993
¥16,084 total
includes taxes & fees
Feb 8 - Feb 9
Wyndham Garden San Diego Near SeaWorld

Kings Inn San Diego

Kings Inn San Diego
2.5 star property
4.9 km from Mission Bay
8.8 out of 10, Excellent, (3,631 reviews)
"Love the Kings Inn, always on our travel list!!"
United States
Linzee
Kings Inn San Diego

Embassy Suites by Hilton San Diego Bay Downtown

Embassy Suites by Hilton San Diego Bay Downtown
4.0 star property
8.7 km from Mission Bay
9.0 out of 10, Wonderful, (1,620 reviews)
"Very easy vacation, convenient breakfast as well as location."
United States
Kathy
The price is ¥26,944
¥36,945 total
includes taxes & fees
Mar 1 - Mar 2
Embassy Suites by Hilton San Diego Bay Downtown

The Bristol Hotel San Diego

The Bristol Hotel San Diego
3.5 star property
8.7 km from Mission Bay
8.6 out of 10, Excellent, (1,485 reviews)
"Great location. Good value for money."
United States
Mohammad
The Bristol Hotel San Diego

Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego
3.0 star property
Gaslamp Quarter, 9.4 km from Mission Bay
9.4 out of 10, Exceptional, (1,004 reviews)
"Great location and stay. "
United States
Simran
The price is ¥16,272
¥23,410 total
includes taxes & fees
Feb 22 - Feb 23
Staypineapple, Hotel Z, Gaslamp San Diego

Bay Club Hotel & Marina

Bay Club Hotel & Marina
3.5 star property
6.8 km from Mission Bay
9.2 out of 10, Wonderful, (3,367 reviews)
"We had great time and enjoyed our stay "
United States
sadra
The price is ¥19,951
¥22,932 total
includes taxes & fees
Feb 24 - Feb 25
Bay Club Hotel & Marina

GreenTree Inn San Diego Mission Bay

GreenTree Inn San Diego Mission Bay
2.5 star property
Pacific Beach, 3 km from Mission Bay
8.0 out of 10, Very Good, (1,927 reviews)
"The staff was very nice and great location"
United States
Curtis
The price is ¥13,807
¥15,872 total
includes taxes & fees
Feb 12 - Feb 13
GreenTree Inn San Diego Mission Bay

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego
4.0 star property
Gaslamp Quarter, 9.7 km from Mission Bay
9.0 out of 10, Wonderful, (3,293 reviews)
"Great place to stay!"
United States
CINDY
The price is ¥31,318
¥43,894 total
includes taxes & fees
Feb 8 - Feb 9
Hard Rock Hotel San Diego

The Encinitan Hotel & Suites

The Encinitan Hotel & Suites
3.0 star property
30.9 km from Mission Bay
8.2 out of 10, Very Good, (1,362 reviews)
"Perfect location with great value. We always like to visit this hotel."
United States
todd
The Encinitan Hotel & Suites

Comfort Inn San Diego Old Town

Comfort Inn San Diego Old Town
2.5 star property
Old Town San Diego, 4 km from Mission Bay
8.2 out of 10, Very Good, (1,961 reviews)
"Room was nice and clean, staff was very accomidating and friendly."
United States
Steve
The price is ¥13,835
¥15,903 total
includes taxes & fees
Feb 22 - Feb 23
Comfort Inn San Diego Old Town

La Quinta Inn & Suites by Wyndham San Diego Mission Bay

La Quinta Inn & Suites by Wyndham San Diego Mission Bay
3.0 star property
North Pacific Beach, 3.5 km from Mission Bay
8.0 out of 10, Very Good, (1,469 reviews)
"Great staff, clean rooms "
United States
Hala
The price is ¥15,989
¥18,383 total
includes taxes & fees
Feb 8 - Feb 9
La Quinta Inn & Suites by Wyndham San Diego Mission Bay
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Mission Bay

Find the best Mission Bay areas and neighborhoods for the activities you enjoy most.

Downtown San Diego

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

Mission Beach

Spanning nearly two miles of oceanfront, this sandbar community offers sunbathing, surfing, and beach volleyball, with nearby attractions like Belmont Park's Giant Dipper Roller Coaster and SeaWorld in Mission Bay Park.

Pacific Beach

Boasting a lively nightlife scene, Pacific Beach offers miles of sandy shores, a bustling 3.2-mile boardwalk, and attractions like Crystal Pier and Kate Sessions Park. Enjoy local shops, bars, and eateries along the vibrant walkway.

Gaslamp Quarter

Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.

Ocean Beach

Ocean Beach is known for its stunning beaches, and with sights like Dog Beach and Ocean Beach Farmers Market, you won't get bored spending a day wandering around this part of San Diego.

Top Mission Bay Hotel Reviews

Frequently asked questions

What is Mission Bay like?
You'll be sure to have fun visiting San Diego's Mission Bay neighborhood. Looking for sights you might find in a travel guide about Mission Bay? Consider a visit to Mission Bay while you're in the neighborhood.
What's a favorite hotel to stay in Mission Bay?
Based on Expedia customer reviews, The Dana on Mission Bay is the highest ranked property in Mission Bay. This hotel offers a marina and 2 outdoor pools. Other favorite options in the area include San Diego Mission Bay Resort and Hyatt Regency Mission Bay Spa and Marina.
How many hotels should I expect to find in Mission Bay?
If you're searching for places to stay in San Diego, Expedia has something to meet your needs with 46 Mission Bay hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in Mission Bay, will I receive a refund?
Yes, you'll find most room reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your check-in date. If your reservation is non-refundable, you might be able to cancel it and be given a refund within a 24-hour period of your booking. Add your dates and click on "Search", then use the filter option "fully refundable" to view the best options available in Mission Bay.
Where can I learn more about changing or cancelling my trip to Mission Bay?
To find more details about updating your trip to Mission Bay or cancelling it, head over to our customer service page.
What is there to do around this San Diego neighborhood?
Enjoy a stroll along the shore at Mission and Pacific Beaches, Ski Beach, and Crown Point Shores while you're in Mission Bay. You could also plan a visit to Mission Bay or Mission Bay Golf Course while you're in the neighborhood. Mission Beach, North Cove Beach, and Bahia Point Beach are just a few of the places to visit in and around Mission Bay. When you're sightseeing in San Diego, Bay City Brewing Co. and Sail Bay are also worth a stop.