Find hotels in Mission Bay, San Diego

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Mission Bay hotels

Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina
4.0 star property
Mission Bay
8.4 out of 10, Very Good, (1597)
"Great staff"
United States
Samuel
The price is ¥22,409
¥34,044 total
includes taxes & fees
Jan 22 - Jan 23
Hyatt Regency Mission Bay Spa and Marina

San Diego Mission Bay Resort

San Diego Mission Bay Resort
4.0 star property
Mission Bay
8.4 out of 10, Very Good, (1331)
"Loved the bay front room with the large grass area right out the door!"
United States
Todd and Danielle
The price is ¥23,819
¥35,660 total
includes taxes & fees
Feb 2 - Feb 3
San Diego Mission Bay Resort

Paradise Point Resort & Spa

Paradise Point Resort & Spa
4.0 star property
Mission Bay
8.6 out of 10, Excellent, (2376)
"Great facility and amenities. We look forward to taking our family back again. "
United States
Andy
The price is ¥17,268
¥28,136 total
includes taxes & fees
Jan 20 - Jan 21
Paradise Point Resort & Spa

The Dana on Mission Bay

The Dana on Mission Bay
3.5 star property
Mission Bay
9.0 out of 10, Wonderful, (3982)
"Great spot, great hotel, great food options!"
United States
Demes SP
The price is ¥21,767
¥28,152 total
includes taxes & fees
Jan 8 - Jan 9
The Dana on Mission Bay

Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego
4.0 star property
Marina District, 9 km from Mission Bay
9.0 out of 10, Wonderful, (2872)
"Excellent stay...wonderful staff"
United States
Michelle
The price is ¥28,816
¥41,945 total
includes taxes & fees
Jan 9 - Jan 10
Manchester Grand Hyatt San Diego

Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
8 km from Mission Bay
8.4 out of 10, Very Good, (5996)
"Perfect location for leaving on a cruise!"
United States
Hope
The price is ¥21,164
¥29,990 total
includes taxes & fees
Jan 11 - Jan 12
Wyndham San Diego Bayside

Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego
3.0 star property
Gaslamp Quarter, 9.4 km from Mission Bay
9.4 out of 10, Exceptional, (1001)
"An excellent stay in an excellent area! Super clean and staff is very nice."
Canada
Emily
The price is ¥16,771
¥23,972 total
includes taxes & fees
Jan 25 - Jan 26
Staypineapple, Hotel Z, Gaslamp San Diego

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection
3.0 star property
8.2 km from Mission Bay
8.8 out of 10, Excellent, (870)
"beautiful hotel , amazing staff, & yummy breakfast!! "
United States
Makayla
The price is ¥15,576
¥18,060 total
includes taxes & fees
Jan 8 - Jan 9
The DEXTRO Little Italy, BW Premier Collection

Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld
3.0 star property
2.6 km from Mission Bay
7.4 out of 10, Good, (4145)
"Get location to the airport, safe, great staff, & overall wonderful stay"
United States
Tyler
The price is ¥13,241
¥15,220 total
includes taxes & fees
Jan 13 - Jan 14
Wyndham Garden San Diego Near SeaWorld

DoubleTree by Hilton San Diego - Del Mar

DoubleTree by Hilton San Diego - Del Mar
4.0 star property
Carmel Valley, 17.8 km from Mission Bay
8.4 out of 10, Very Good, (1944)
"Clean room, staff was friendly, great location, quiet."
United States
Vicheka
The price is ¥19,133
¥21,801 total
includes taxes & fees
Jan 25 - Jan 26
DoubleTree by Hilton San Diego - Del Mar

Hampton Inn San Diego-Downtown

Hampton Inn San Diego-Downtown
2.5 star property
7.8 km from Mission Bay
8.2 out of 10, Very Good, (2337)
"Nice and convenient place to stay!"
United States
Esperanza
The price is ¥16,710
¥19,374 total
includes taxes & fees
Jan 21 - Jan 22
Hampton Inn San Diego-Downtown

Hilton San Diego Bayfront

Hilton San Diego Bayfront
4.0 star property
Marina District, 10 km from Mission Bay
8.6 out of 10, Excellent, (1907)
"Beautiful hotel "
United States
Crystal
The price is ¥28,072
¥40,207 total
includes taxes & fees
Jan 10 - Jan 11
Hilton San Diego Bayfront

The Bristol Hotel San Diego

The Bristol Hotel San Diego
3.5 star property
8.7 km from Mission Bay
8.6 out of 10, Excellent, (1467)
"Very nice staff and clean rooms"
United States
Desserae
The Bristol Hotel San Diego

Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina
4.0 star property
Marina District, 9.2 km from Mission Bay
9.2 out of 10, Wonderful, (1968)
"Great place for families!!"
Canada
Ilijana
The price is ¥32,416
¥45,806 total
includes taxes & fees
Jan 23 - Jan 24
Marriott Marquis San Diego Marina

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego
4.0 star property
Gaslamp Quarter, 9.7 km from Mission Bay
9.0 out of 10, Wonderful, (3207)
"Beautiful hotel"
United States
Jordan M.
The price is ¥74,562
¥93,919 total
includes taxes & fees
Feb 3 - Feb 4
Hard Rock Hotel San Diego

Kings Inn San Diego

Kings Inn San Diego
2.5 star property
4.9 km from Mission Bay
8.8 out of 10, Excellent, (3591)
"Good location, friendly staff"
Canada
Natalia
Kings Inn San Diego

Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel
3.5 star property
16.7 km from Mission Bay
9.2 out of 10, Wonderful, (3631)
"The hotel and staff were great. "
United States
Rosa
The price is ¥20,201
¥22,260 total
includes taxes & fees
Jan 8 - Jan 9
Best Western Plus Marina Gateway Hotel

Embassy Suites by Hilton San Diego Bay Downtown

Embassy Suites by Hilton San Diego Bay Downtown
4.0 star property
Marina District, 8.7 km from Mission Bay
9.0 out of 10, Wonderful, (1588)
"Perfect location , friendly staff , good buffet"
United States
Patricio
The price is ¥27,458
¥37,517 total
includes taxes & fees
Feb 1 - Feb 2
Embassy Suites by Hilton San Diego Bay Downtown

Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
6 km from Mission Bay
8.4 out of 10, Very Good, (3221)
"We have stayed here before and it’s always amazing "
United States
debora
The price is ¥26,465
¥36,059 total
includes taxes & fees
Jan 11 - Jan 12
Sheraton San Diego Resort

Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy
4.0 star property
Little Italy, 8.1 km from Mission Bay
8.8 out of 10, Excellent, (197)
"Great stay"
United States
Adilene
The price is ¥21,141
¥24,513 total
includes taxes & fees
Jan 22 - Jan 23
Courtyard by Marriott San Diego Downtown Little Italy
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Mission Bay

Find the best Mission Bay areas and neighborhoods for the activities you enjoy most.

Downtown San Diego

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

Gaslamp Quarter

Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.

Pacific Beach

Boasting a lively nightlife scene, Pacific Beach offers miles of sandy shores, a bustling 3.2-mile boardwalk, and attractions like Crystal Pier and Kate Sessions Park. Enjoy local shops, bars, and eateries along the vibrant walkway.

Mission Beach

Spanning nearly two miles of oceanfront, this sandbar community offers sunbathing, surfing, and beach volleyball, with nearby attractions like Belmont Park's Giant Dipper Roller Coaster and SeaWorld in Mission Bay Park.

Ocean Beach

Ocean Beach is known for its stunning beaches, and with sights like Dog Beach and Ocean Beach, you won't get bored spending a day wandering around this part of San Diego.

Top Mission Bay Hotel Reviews

Frequently asked questions

What is Mission Bay like?
You'll be sure to have fun visiting San Diego's Mission Bay neighborhood. Looking for sights you might find in a travel guide about Mission Bay? Consider a visit to Mission Bay while you're in the neighborhood.
What's a favorite hotel to stay in Mission Bay?
Based on Expedia customer reviews, Paradise Point Resort & Spa is the highest ranked property in Mission Bay. This resort offers a marina and 5 outdoor pools. Other favorite options in the area include The Dana on Mission Bay and San Diego Mission Bay Resort.
How many hotels should I expect to find in Mission Bay?
If you're searching for places to stay in San Diego, Expedia has something to meet your needs with 46 Mission Bay hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in Mission Bay, will I receive a refund?
Yes, you'll find most room reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your check-in date. If your reservation is non-refundable, you might be able to cancel it and be given a refund within a 24-hour period of your booking. Add your dates and click on "Search", then use the filter option "fully refundable" to view the best options available in Mission Bay.
Where can I learn more about changing or cancelling my trip to Mission Bay?
To find more details about updating your trip to Mission Bay or cancelling it, head over to our customer service page.
What is there to do around this San Diego neighborhood?
Enjoy a stroll along the shore at Mission and Pacific Beaches, Ski Beach, and Crown Point Shores while you're in Mission Bay. You could also plan a visit to Mission Bay or North Cove Beach while you're in the neighborhood. Mission Beach and Hotel Circle are some favorite places to visit in the area around Mission Bay. When you're sightseeing in San Diego, Bahia Point Beach and Bay City Brewing Co. are also worth a stop.