Find hotels near Medical University of South Carolina, Charleston from ￥27,385

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Nov 30 - Dec 1
Tomorrow
Dec 1 - Dec 2
Next weekend
Dec 5 - Dec 7
In two weeks
Dec 12 - Dec 14

Filter by

Guest rating
Guest rating
Star rating

Compare 4,896 hotels close to Medical University of South Carolina with room rates, reviews, and availability. Most hotels are fully refundable.

Frette Italian sheets, premium bedding, pillowtop beds, in-room safe
86 Cannon Charleston - Adults Only

86 Cannon Charleston - Adults Only

4.5 star property
Cannonborough Elliotborough, 0.4 km from Medical University of South Carolina
10.0 out of 10, Exceptional, (72)
"The perfect place to stay if your visiting Charleston "
United States
Stephanie
The price is ￥59,091
￥67,365 total
includes taxes & fees
Dec 2 - Dec 3
86 Cannon Charleston - Adults Only
Exterior
The Iris Charleston

The Iris Charleston

3.0 star property
Cannonborough Elliotborough, 0.9 km from Medical University of South Carolina
9.8 out of 10, Exceptional, (119)
"Clean room and well located"
United States
Stephen
The price is ￥14,650
￥27,385 total
includes taxes & fees
Dec 7 - Dec 8
The Iris Charleston
Terrace/patio
The Nickel Hotel

The Nickel Hotel

4.0 star property
King Street, 0.8 km from Medical University of South Carolina
9.8 out of 10, Exceptional, (74)
"Everything about this new hotel is spot on-elegant design and a sweet and attentive staff within a private refuge-despite an often busy central downtown location."
United States
Christine
The price is ￥41,094
￥47,182 total
includes taxes & fees
Dec 7 - Dec 8
The Nickel Hotel
Front of property
French Quarter Inn

French Quarter Inn

4.0 star property
French Quarter, 1.8 km from Medical University of South Carolina
10.0 out of 10, Exceptional, (1015)
"Phenomenal stay - highly recommend"
United States
Patricia
French Quarter Inn
Terrace/patio
The Pinch Hotel

The Pinch Hotel

4.0 star property
King Street, 1.2 km from Medical University of South Carolina
9.8 out of 10, Exceptional, (170)
"Large room with great city views. Well stocked mini bar. Front desk was very friendly and helpful. Great location."
United States
Paul
The Pinch Hotel
Rooftop terrace
The Loutrel

The Loutrel

4.0 star property
French Quarter, 1.9 km from Medical University of South Carolina
10.0 out of 10, Exceptional, (1010)
"Beautiful hotel in a great location "
United States
Sean
The Loutrel
Room, 1 King Bed | Premium bedding, down comforters, memory foam beds
Luxurious Private Suites in Downtown Charleston

Luxurious Private Suites in Downtown Charleston

3.0 star property
Cannonborough Elliotborough, 0.6 km from Medical University of South Carolina
9.6 out of 10, Exceptional, (69)
"Property was very clean and had all the amenities of a hotel but a lot more room. Bed was very comfortable as well which is a rarity in my opinion. Great walking options for dining. Host was excellent with anything we needed! Did not use the pool so cannot comment."
United States
Helen
The price is ￥25,301
￥42,197 total
includes taxes & fees
Dec 1 - Dec 2
Luxurious Private Suites in Downtown Charleston
Microwave, coffee/tea maker, highchair, blender
Hilton Club Liberty Place Charleston

Hilton Club Liberty Place Charleston

3.5 star property
Ansonborough, 1.6 km from Medical University of South Carolina
9.8 out of 10, Exceptional, (877)
"Staff was friendly very clean really nice place "
United States
Salvatore
The price is ￥33,190
￥37,838 total
includes taxes & fees
Dec 7 - Dec 8
Hilton Club Liberty Place Charleston
Apartment | Laptop workspace, iron/ironing board, free WiFi, bed sheets
Perfect Location in Downtown Charleston

Perfect Location in Downtown Charleston

3.5 star property
Cannonborough Elliotborough, 0.7 km from Medical University of South Carolina
9.6 out of 10, Exceptional, (16)
"This was the cutest place and it had everything we needed! The location was amazing!! 10/10, we’re already talking about coming back! "
United States
Alexandra
The price is ￥25,301
￥89,348 total
includes taxes & fees
Dec 2 - Dec 3
Perfect Location in Downtown Charleston
Anson Suite | Frette Italian sheets, premium bedding, Tempur-Pedic beds, in-room safe
Zero George Street

Zero George Street

5.0 star property
Ansonborough, 1.6 km from Medical University of South Carolina
9.8 out of 10, Exceptional, (353)
"A delightful stay in a delightful setting. "
United States
Tommy
The price is ￥46,930
￥54,214 total
includes taxes & fees
Dec 1 - Dec 2
Zero George Street
Outdoor pool, cabanas (surcharge), pool umbrellas
Hotel Bennett

Hotel Bennett

5.0 star property
King Street, 1 km from Medical University of South Carolina
9.6 out of 10, Exceptional, (971)
"Great place to stay! Will definitely stay there again!"
United States
Leigh Regenold
The price is ￥67,001
￥76,737 total
includes taxes & fees
Dec 16 - Dec 17
Hotel Bennett
Front of property
The Spectator Hotel

The Spectator Hotel

4.0 star property
French Quarter, 1.9 km from Medical University of South Carolina
9.8 out of 10, Exceptional, (976)
"Staff was exceptional, friendly…like staying at a friends house!"
United States
Jonathan
The Spectator Hotel
Outdoor pool
The Nicholas

The Nicholas

3.0 star property
Harleston Village, 1 km from Medical University of South Carolina
9.6 out of 10, Exceptional, (31)
"We loved The Nicholas! Spacious room and bathroom! Loved the porch and the location is unmatched. We’ll be back!"
United States
Leah
The price is ￥29,518
￥38,309 total
includes taxes & fees
Dec 1 - Dec 2
The Nicholas
Egyptian cotton sheets, premium bedding, pillowtop beds, minibar
The Restoration

The Restoration

4.0 star property
King Street, 1.3 km from Medical University of South Carolina
9.6 out of 10, Exceptional, (1017)
"Great place to stay for a few nights while visiting!"
United States
Kelly
The price is ￥36,827
￥43,276 total
includes taxes & fees
Dec 1 - Dec 2
The Restoration
Charleston Flat | 1 bedroom, premium bedding, minibar, in-room safe
The Dewberry Charleston

The Dewberry Charleston

5.0 star property
Ansonborough, 1.2 km from Medical University of South Carolina
9.6 out of 10, Exceptional, (1003)
"Great location for downtown Charleston. Walkable to King Street shopping and restaurants. "
United States
Christopher
The price is ￥55,508
￥63,634 total
includes taxes & fees
Dec 8 - Dec 9
The Dewberry Charleston
Breakfast, dinner served; American cuisine, garden views
Planters Inn

Planters Inn

4.5 star property
Ansonborough, 1.6 km from Medical University of South Carolina
9.6 out of 10, Exceptional, (1019)
"Great place to stay!"
United States
Anne
The price is ￥35,968
￥41,003 total
includes taxes & fees
Dec 8 - Dec 9
Planters Inn
View from property
HarbourView Inn

HarbourView Inn

4.0 star property
French Quarter, 2.1 km from Medical University of South Carolina
9.8 out of 10, Exceptional, (1007)
"Room was very clean, location perfect. "
United States
Sandra
HarbourView Inn
Restaurant
Andrew Pinckney Inn

Andrew Pinckney Inn

4.0 star property
Ansonborough, 1.7 km from Medical University of South Carolina
9.6 out of 10, Exceptional, (1426)
"Great place to stay in Charleston! "
United States
Amy
Andrew Pinckney Inn
Restaurant
Hotel Richemont

Hotel Richemont

4.0 star property
King Street, 1.3 km from Medical University of South Carolina
9.6 out of 10, Exceptional, (52)
"Top notch hotel. Would highly recommend!"
United States
Dave
The price is ￥47,421
￥54,062 total
includes taxes & fees
Dec 8 - Dec 9
Hotel Richemont
Lobby
The Charleston Place

The Charleston Place

5.0 star property
Charleston Historic District, 1.5 km from Medical University of South Carolina
9.6 out of 10, Exceptional, (1012)
"Beautiful hotel, wonderful staff"
United States
susan
The price is ￥163,208
￥193,534 total
includes taxes & fees
Dec 31 - Jan 1, 2026
The Charleston Place
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Medical University of South Carolina Hotel Reviews

The Vendue

The Vendue

10/10 Excellent
"Staff was great. Very clean rooms."
Gerald 1-night trip
Posted 22 hours ago
The Vendue

Hotels near other Medical University of South Carolina attractions

Waring Historical Library

Learn about the local history of Charleston when you spend time at Waring Historical Library. Discover the lively bars and acclaimed art scene in this walkable area.
See properties

Macaulay Museum of Dental History

You can browse the exhibits at Macaulay Museum of Dental History, a museum with a story of its own, during your travels to Charleston. Stroll along the area's beautiful beaches, or simply savor its lively bars.
See properties

Frequently asked questions

What's the area like around Medical University of South Carolina?
Medical University of South Carolina is located in a historic area of Charleston known for its array of dining options and stunning churches. If you're looking for a convenient place to stay, check out the 1169 hotels and other accommodations you'll find within a mile.
Where is the best place to stay close to Medical University of South Carolina?
Adjacent to Medical University of South Carolina, The Ashley is one of the top choices for your stay based on our traveler data, and this B&B offers free breakfast and free parking. Other good choices close by include The Francis Marion Hotel and Hyatt Place Charleston/Historic District.
How many hotels will I be able to find near Medical University of South Carolina?
Expedia has 1169 hotels and other accommodations within a mile from Medical University of South Carolina.
If I need to cancel the hotel reservation for my stay near Medical University of South Carolina, will I receive a refund?
Yes! Most hotel reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a non-refundable reservation, you might still have the option to cancel and get a refund within 24 hours of booking. Add dates, click "Search", then filter by "fully refundable" to view the top deals on offer near Medical University of South Carolina.
Where can I learn more about changing or cancelling my trip in the area near Medical University of South Carolina?
To access more information about picking new dates or cancelling your stay near Medical University of South Carolina, go to https://www.expedia.com/service/.
What can I see and do near Medical University of South Carolina?
Study the collections at Charleston Museum, Aiken-Rhett House Museum, or Gibbes Museum of Art. Sights like Charleston Music Hall, Charleston City Market, and Dock Street Theater are landmarks to visit in the area. You can catch a show at Music Farm, Charleston Gaillard Center, and The Riviera Theater.

Explore a world of travel with Expedia