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Our top choices for Mayo hotels

A buffet with various food items, including omelets and cheese.
A reception desk with a modern design, a blue geometric wall pattern, and a wooden accent wall.
A hotel room with two beds, a desk, and a view of the outdoors.
A modern lobby with a sofa, chairs, a desk, and a map mural on the wall.

1. Holiday Inn Express Gaffney by IHG

Holiday Inn Express Gaffney by IHG
Gaffney
United States
Ron
￥13,417
￥14,624 total
includes taxes & fees
Oct 11 - Oct 12
Holiday Inn Express Gaffney by IHG
A hotel lobby with a bar area, seating with patterned upholstery, and a central coffee table.
A hotel reception desk with a 'Welcome to the Palmetto State' sign, a 'Manager On Duty' sign, and a 'Hilton Honors' sign.
A snack and beverage vending area with various snacks and drinks.
A fitness center with treadmills, a bench, and exercise equipment.

2. Hampton Inn Gaffney

Hampton Inn Gaffney
Gaffney
United States
George
￥15,600
￥17,004 total
includes taxes & fees
Oct 31 - Nov 1
Hampton Inn Gaffney
A modern living room with a fireplace, two sofas, and a coffee table.
A modern gym with various exercise equipment, motivational wall graphics, and a large window offering a view of the outdoors.
A hotel lobby with multiple seating areas, a reception desk, and a fireplace.
A hotel room with two beds, a desk, a TV, and a window with curtains.

3. Best Western Spartanburg Northwest

Best Western Spartanburg Northwest
Spartanburg
United States
Darius
￥14,625
￥16,557 total
includes taxes & fees
Nov 1 - Nov 2
Best Western Spartanburg Northwest
A modern lobby with a blue sofa, a reception desk, and a large cityscape painting.
A hotel room with two beds, a nightstand, and a wall-mounted TV.
A Best Western Plus hotel with a parking lot and multiple cars parked in front.
A modern restaurant with a bar area, large windows, and a kitchen visible in the background.

4. Best Western Plus Spartanburg

Best Western Plus Spartanburg
Spartanburg
United States
Jamie
￥14,396
￥16,298 total
includes taxes & fees
Oct 11 - Oct 12
Best Western Plus Spartanburg
Room
A modern kitchen with wooden cabinets, a built-in oven, and a coffee station.
A modern lobby with a large white reception desk, brown leather sofas, a round coffee table, and a ceiling light fixture.
A reception area with wooden reception desks, framed artwork, and a white door.

5. Days Inn by Wyndham Spartanburg

Days Inn by Wyndham Spartanburg
Boiling Springs
United States
antonio
￥11,223
￥12,457 total
includes taxes & fees
Oct 4 - Oct 5
Days Inn by Wyndham Spartanburg
A lobby with a reception desk, a clock, and an exit sign.
A multi-story building with a parking lot in front.
A laundry room with multiple washing machines and dryers, wooden flooring, and informational posters on the walls.
A clean, modern office space with vending machines, a coffee machine, and a trash can.

6. USA Economy Lodge

USA Economy Lodge
Spartanburg
United States
Brandy
￥9,092
￥10,093 total
includes taxes & fees
Oct 13 - Oct 14
USA Economy Lodge
A hotel dining area with multiple tables and chairs, a television mounted on a wall, and a kitchen area visible in the background.
A living room with a sofa, two armchairs, a coffee table, and a patterned rug.
A Sleep Inn hotel entrance with a clear sky, a flagpole, and a parking lot.
A hotel with a swimming pool, lounge chairs, and a covered seating area.

7. Sleep Inn Gaffney at I-85

Sleep Inn Gaffney at I-85
Gaffney
United States
Wendy
￥10,608
￥11,881 total
includes taxes & fees
Oct 23 - Oct 24
Sleep Inn Gaffney at I-85
A hotel room with two beds, a desk, a refrigerator, a television, and a bathroom visible through an arched doorway.
A modern bathroom with a large bathtub, a chair, and a floor lamp.
A hotel with a well-lit entrance, multiple parking spaces, and a clear view of the sky.
A reception desk with a wooden finish, a clock, and two card readers.

8. Comfort Inn & Suites Spartanburg North

Comfort Inn & Suites Spartanburg North
Spartanburg
United States
Lisa
￥13,283
￥14,745 total
includes taxes & fees
Oct 25 - Oct 26
Comfort Inn & Suites Spartanburg North
A modern reception area with a counter, seating, and a bookshelf with various items.
A multi-story hotel with a stone facade and multiple windows, featuring a parking lot and landscaped areas.
A clinical setting with medical equipment, a large mirror, and a window providing natural light.
A bar area with a long counter, bar stools, and a variety of bottles and glasses.

9. Holiday Inn Spartanburg Northwest by IHG

Holiday Inn Spartanburg Northwest by IHG
Spartanburg
United States
Carla
￥15,943
￥17,699 total
includes taxes & fees
Oct 11 - Oct 12
Holiday Inn Spartanburg Northwest by IHG
A lobby with a leather sofa, two lamps, a painting, and potted plants.
A hotel lobby with a reception desk, a waiting area with a chair, and a large window providing a view of the outside.
A swimming pool with a brick border and a metal ladder, surrounded by a fence and a house in the background.
A hotel room with two beds, a desk, a chair, a TV, and a bathroom visible through an open door.

10. Quality Inn Gaffney I-85

Quality Inn Gaffney I-85
Gaffney
United States
Betina
￥7,889
￥8,834 total
includes taxes & fees
Oct 25 - Oct 26
Quality Inn Gaffney I-85
A hotel room with a bed, a blue sofa, a wooden coffee table, a desk with a chair, and a framed abstract painting on the wall.
A hotel room with a blue sofa, a wooden coffee table, a bed with white linens, a desk with a chair, and a large window.
A large indoor swimming pool with a diving board, multiple doors, and seating areas.
A food service counter with a sign that reads "EXPRESS START".

11. Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
Spartanburg
United States
Michael
￥15,627
￥17,345 total
includes taxes & fees
Nov 1 - Nov 2
Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
A conference room with a long table, blue and orange chairs, and a reception desk in the background.
A conference room with two desks, two chairs, and a small table.
A coffee station with labeled dispensers for hot water, decaf roast, light roast, and dark roast coffee.
A gym with treadmills, elliptical machines, and weight machines.

12. Hampton Inn Spartanburg-North I-85

Hampton Inn Spartanburg-North I-85
Spartanburg
United States
Britt
￥19,286
￥21,408 total
includes taxes & fees
Nov 3 - Nov 4
Hampton Inn Spartanburg-North I-85
A modern living room with a stone accent wall, a flat-screen TV, and a blue abstract rug.
A modern lobby with a sofa, armchairs, and a coffee table. There is a reception desk and a dining area in the background.
A modern hotel with a prominent Fairfield sign, multiple floors, and a well-lit entrance.
A modern dining area with wooden flooring, round tables, and chairs. There are wall-mounted artworks and a sign that reads "LESS MONDAY MORE SUMMER".

13. Fairfield by Marriott Inn & Suites Spartanburg Downtown

Fairfield by Marriott Inn & Suites Spartanburg Downtown
Spartanburg
United States
Zachary
￥20,678
￥22,953 total
includes taxes & fees
Oct 11 - Oct 12
Fairfield by Marriott Inn & Suites Spartanburg Downtown
A hotel reception area with a digital sign indicating free Wi-Fi availability.
A hotel with a covered parking area, a brick facade, and a clear sky.
A restaurant with red chairs and a counter with food items.
A hotel room with two beds, a desk, a chair, a television, and a mirror.

14. Red Roof Inn Gaffney

Red Roof Inn Gaffney
Gaffney
United States
Belinda
￥9,821
￥10,999 total
includes taxes & fees
Oct 11 - Oct 12
Red Roof Inn Gaffney
A hotel lobby with a curved outdoor seating area, a fire pit, and a pool.
A grand hotel lobby with a marble staircase, ornate carpet, and large landscape paintings on the walls.
A modern kitchen with marble countertops, wooden shelves, and a wine station.
A spacious lobby with a high ceiling, chandeliers, a registration desk, and potted plants.

15. Spartanburg Marriott

Spartanburg Marriott
Spartanburg
United States
Daniel
￥18,626
￥20,675 total
includes taxes & fees
Oct 25 - Oct 26
Spartanburg Marriott
A hotel lobby with a reception desk, green sofa, patterned armchairs, and a potted plant.
A kitchen with wooden cabinets, a black refrigerator, and a dining area with chairs and a table.
A motel with multiple rooms, a blue awning, and a red car parked in front.
A swimming pool with lounge chairs, a lifeguard station, and a multi-story building with balconies.

16. Baymont by Wyndham Gaffney

Baymont by Wyndham Gaffney
Gaffney
United States
Kelly
￥9,518
￥10,662 total
includes taxes & fees
Oct 18 - Oct 19
Baymont by Wyndham Gaffney
An outdoor seating area with sofas, a fire pit, and string lights.
A self-service kiosk with a variety of snacks and beverages, a microwave, and a refrigerated display.
A modern lounge area with seating arrangements, a large window offering a view of the outdoors, and contemporary lighting fixtures.
A modern hotel with a multi-story structure, large windows, and a prominent vertical light strip.

17. Tru by Hilton Spartanburg

Tru by Hilton Spartanburg
Spartanburg
United States
Anthony
￥16,716
￥18,556 total
includes taxes & fees
Nov 1 - Nov 2
Tru by Hilton Spartanburg
A multi-level hotel lobby with seating areas, a fireplace, and a staircase.
A modern hotel building with a large glass facade, a covered entrance, and a sign reading "Four Points by Sheraton".
A spacious lobby with a high ceiling, modern furniture, and large windows offering views of the outdoors.
A modern coffee bar with a glass display case, seating area with round tables and chairs, and a wooden ceiling.

18. Four Points by Sheraton Spartanburg

Four Points by Sheraton Spartanburg
Spartanburg
United States
John
￥17,616
￥19,552 total
includes taxes & fees
Oct 11 - Oct 12
Four Points by Sheraton Spartanburg
A modern bedroom with a large bed, a built-in TV, and a small desk.
A reception area with a modern design, including a large number '6' sign, a coffee machine, and a TV mounted on the wall.
A laundry room with three stacked washing machines, a power outlet, and a water heater.
A motel with multiple floors, balconies, and a parking lot.

19. Motel 6 Spartanburg, Sc – Northwest / Business 85

Motel 6 Spartanburg, Sc – Northwest / Business 85
Spartanburg
United States
Tyler
￥9,122
￥10,126 total
includes taxes & fees
Oct 21 - Oct 22
Motel 6 Spartanburg, Sc – Northwest / Business 85
A rooftop bar with seating, a bar area, and a view of the cityscape at dusk.
A spacious living area with a modern sofa, armchairs, a coffee table, and a dining area with chairs and a table.
A swimming pool with steps leading up to a building entrance, surrounded by lounge chairs and umbrellas.
A modern living room with a dark-colored sofa, armchairs, a coffee table, and a bookshelf filled with decorative items.

20. AC Hotel by Marriott Spartanburg

AC Hotel by Marriott Spartanburg
Spartanburg
United States
Willow
￥26,677
￥29,611 total
includes taxes & fees
Oct 11 - Oct 12
AC Hotel by Marriott Spartanburg
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Top Mayo Hotel Reviews

Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

10/10 Excellent
"Great staff!"
Roberta 2-night trip
Posted 2 hours ago
Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
Comfort Suites At WestGate Mall

Comfort Suites At WestGate Mall

10/10 Excellent
"Every was perfect"
Nailea 1-night trip
Posted 9 hours ago
Comfort Suites At WestGate Mall
Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

10/10 Excellent
"Great place to stop, restaurants within walking distance plus mall."
Melinda 1-night trip
Posted 1 day ago
Hampton Inn & Suites Spartanburg-I-26-Westgate Mall
Best Western Spartanburg I-26

Best Western Spartanburg I-26

10/10 Excellent
"Our stay for one night was exceptional. The service and the room."
Tammy 1-night trip
Posted 1 day ago
Best Western Spartanburg I-26
Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG

Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG

10/10 Excellent
"From the check -in to check- out, everything and everyone was top notch!"
Amy 1-night trip
Posted 3 days ago
Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG
Hilton Garden Inn Spartanburg

Hilton Garden Inn Spartanburg

10/10 Excellent
"The hotel was clean and so well landscaped. We really enjoyed the restaurant. The only thing is that when we asked for towels , we had to go get them after we asked twice. also the clerk must have many tasks because the one person manning the desk was not readily available. We had to wait several times for their return. Thank you for the complimentary bottled water."
Darlene 6-night trip
Posted 4 days ago
Hilton Garden Inn Spartanburg
Best Western Plus Spartanburg

Best Western Plus Spartanburg

10/10 Excellent
"I'll keep booking here, staff is always so nice and the rooms are always clean!!"
Shannon 3-night trip
Posted 5 days ago
Best Western Plus Spartanburg
Spartanburg Marriott

Spartanburg Marriott

10/10 Excellent
"Professional and polite staff, the grounds were well maintained, ample useful and attractive all while being well located for my purposes."
Daniel 2-night trip
Posted 6 days ago
Spartanburg Marriott

More cheap stays in Mayo

Rodeway Inn Expo Center

Rodeway Inn Expo Center

2070 New Cut Rd Spartanburg SC
￥8,461
￥9,392 total
Oct 24 - Oct 25
includes taxes & fees
5.8/10 (500 reviews)
Rodeway Inn Expo Center
Motel 6 Spartanburg, Sc – Northwest / Business 85

Motel 6 Spartanburg, Sc – Northwest / Business 85

820 Hospitality Drive Spartanburg SC
￥9,122
￥10,126 total
Oct 21 - Oct 22
includes taxes & fees
Motel 6 Spartanburg, Sc – Northwest / Business 85
WoodSpring Suites Spartanburg - Duncan

WoodSpring Suites Spartanburg - Duncan

255 Frontage Rd. Duncan SC
￥10,102
￥11,367 total
Oct 4 - Oct 5
includes taxes & fees
6/10 (293 reviews)
WoodSpring Suites Spartanburg - Duncan
Comfort Suites At WestGate Mall

Comfort Suites At WestGate Mall

458 West Blackstock Road Spartanburg SC
￥14,299
￥15,872 total
Nov 1 - Nov 2
includes taxes & fees
8.4/10 Very Good! (1,002 reviews)
Comfort Suites At WestGate Mall
Best Western Spartanburg I-26

Best Western Spartanburg I-26

488 South Blackstock Road Spartanburg SC
￥15,297
￥16,980 total
Oct 11 - Oct 12
includes taxes & fees
9.2/10 Wonderful! (52 reviews)
Best Western Spartanburg I-26
Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

161 Sha Ln Spartanburg SC
￥15,627
￥17,345 total
Nov 1 - Nov 2
includes taxes & fees
8.6/10 Excellent! (1,002 reviews)
Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

Frequently asked questions

Where is the best place to stay in Mayo?
Best Western Spartanburg I-26, located 13.4 mi (21.5 km) from the heart of Mayo, is a top choice for your stay based on our traveler data. Other good options for your trip to the area are Comfort Suites At WestGate Mall and Spartanburg Marriott. See all available top hotels, or vacation rentals in Mayo.
What are some of the best vacation home rentals in Mayo?
Bungalow Home with EV charger - No Cleaning Fee: Visitors like this Mayo vacation home rental. It offers a balcony, a garden, and air-conditioning to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave. Make the most of the selection of games in this rental home to help you unwind. See all vacation rentals in Mayo.
If I need to cancel my hotel reservation in Mayo, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of check in. If your reservation is non-refundable, you may still be able to cancel and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Mayo.
Where can I learn more about changing or cancelling my trip to Mayo?
For additional details about changing or cancelling your trip to Mayo, head over to our customer service page.
How is it staying in Mayo?
Travelers to Mayo will find plenty to explore and enjoy. There are 500 hotels and other accommodations in the surrounding area. Find out more about Mayo.
What are the top places to visit in Mayo?
Places to visit in the wider area include Lake Blalock Park, Gaffney Outlet Marketplace, and G.B. Hodge Center. You'll also find Woodfin Ridge Golf Club and Asheville Highway Commons in the area. Check out what more to see and do in Expedia's Mayo guide.
What's the weather like in Mayo?
The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 46°F. Average annual precipitation for Mayo is 52 inches.

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