Photo by Amber Palmer

Find hotels near Mayo Clinic Florida, Jacksonville from ￥13,109

    Plan, book, stay with confidence
    bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Filter by

Popular filters
Popular filters
Price per night
Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Popular locations
1
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility
Traveler experience
Traveler experience

Compare 1,902 hotels close to Mayo Clinic Florida with room rates, reviews, and availability. Most hotels are fully refundable.

Salt Air Inn & Suites
BBQ/picnic area
Salt Air Inn & Suites
2.5 star property
9.8 out of 10, Exceptional, (161)
"Very best customer service I have ever had! The staff seems totally focused on the guests being happy. It was simply a pleasure staying at Salt Air. Walking distance to the beach and restaurants. A bonus is there are bicycles to use. Room was very clean and the air conditioning kept us cool. "
The price is ￥15,850
￥17,990 total
includes taxes & fees
May 14 - May 15
Salt Air Inn & Suites
The Hotel Palms
Standard Room, 2 Queen Beds, Non Smoking | Down comforters, minibar, iron/ironing board, WiFi
The Hotel Palms
3.5 star property
9.6 out of 10, Exceptional, (267)
"The staff are extremely friendly. The hotel rooms are clean and spacious. I was a bit disappointed that the desk closed before 6p. I needed ice and was not able to get any. Also, the person rooming with me did not have a parking pass. We had to call to inform them about her car so it would not get towed. All in all it was a great experience. We had left some things in the room and they held them for us until we could pick them up. "
The price is ￥33,493
￥38,015 total
includes taxes & fees
May 14 - May 15
The Hotel Palms
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
Outdoor banquet area
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
9.4 out of 10, Exceptional, (254)
"Cleanliness and transportation to and from the Mayo Clinic "
The price is ￥25,392
￥28,820 total
includes taxes & fees
Jun 2 - Jun 3
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free
Residence Inn by Marriott Jacksonville South/Bartram Park
Property amenity
Residence Inn by Marriott Jacksonville South/Bartram Park
3.0 star property
9.4 out of 10, Exceptional, (463)
"Excellent room- lots of space and storage. Clean. Check in was late due to family emergency but smooth and professional. After that, sometimes no one manned the desk or even looked up. If I asked for a clean towel (because I did not seek room clean for 4 days), I felt like I was a nuisance.No “lounge” service at all despite advertising they had one. Apparently there was no one to work it. "
The price is ￥19,488
￥22,119 total
includes taxes & fees
May 19 - May 20
Residence Inn by Marriott Jacksonville South/Bartram Park
Hampton Inn & Suites Jacksonville Deerwood Park
Studio, 2 Queen Beds, Accessible, Non Smoking | Living area | LCD TV
Hampton Inn & Suites Jacksonville Deerwood Park
2.5 star property
9.2 out of 10, Wonderful, (1004)
"Great place! Very clean. "
The price is ￥16,076
￥18,247 total
includes taxes & fees
Jun 9 - Jun 10
Hampton Inn & Suites Jacksonville Deerwood Park
Tru By Hilton Jacksonville St Johns Town Center
Breakfast area
Tru By Hilton Jacksonville St Johns Town Center
2.5 star property
9.2 out of 10, Wonderful, (589)
"First time at this or any Tru by HILTON. Very pleased with the property and the convenient location. I would consider this an economical yet minimalist hotel. Very clean, comfortable and well appointed though not lush which was the price point I was looking for. The free breakfast was more than adequate and tasty, quite a number of options. Coffee available all day. Decent workout area. Staff very pleasant and welcoming. Definitely returning on my several trips a year north from south Florida. "
The price is ￥20,915
￥23,739 total
includes taxes & fees
Jun 4 - Jun 5
Tru By Hilton Jacksonville St Johns Town Center
Four Points by Sheraton Jacksonville Beachfront
Exterior
Four Points by Sheraton Jacksonville Beachfront
3.0 star property
9.0 out of 10, Wonderful, (1003)
"Great location and property "
The price is ￥35,674
￥40,491 total
includes taxes & fees
May 19 - May 20
Four Points by Sheraton Jacksonville Beachfront
Holiday Inn Express Jacksonville Beach, an IHG Hotel
Standard Room, 2 Queen Beds, Accessible (Accessible Tub) | In-room safe, desk, laptop workspace, blackout drapes
Holiday Inn Express Jacksonville Beach, an IHG Hotel
2.5 star property
9.0 out of 10, Wonderful, (1007)
"we enjoyed a nice walk to the Beach, and enjoyed the Pool area as it was very quiet, except for the construction down the street! The staff was very pleasant and didn't hesitate to greet us every time we went by!! The breakfast was very good and the 24hr Coffee was awesome!"
The price is ￥21,342
￥24,222 total
includes taxes & fees
May 19 - May 20
Holiday Inn Express Jacksonville Beach, an IHG Hotel
Hampton Inn & Suites Jacksonville South - Bartram Park
Outdoor pool, sun loungers
Hampton Inn & Suites Jacksonville South - Bartram Park
3.0 star property
9.0 out of 10, Wonderful, (1003)
"Hotel was undergoing renovations. Our room was recently renovated and was very clean. Staff was very professional and helpful."
The price is ￥15,111
￥17,152 total
includes taxes & fees
Jun 2 - Jun 3
Hampton Inn & Suites Jacksonville South - Bartram Park
Best Western Oceanfront
On the beach
Best Western Oceanfront
3.0 star property
8.8 out of 10, Excellent, (1008)
"Awesome place to stay. So close to the beach and tons of shopping and food options. "
The price is ￥23,303
￥26,448 total
includes taxes & fees
May 27 - May 28
Best Western Oceanfront
Residence Inn by Marriott Jacksonville Butler Boulevard
Outdoor pool
Residence Inn by Marriott Jacksonville Butler Boulevard
3.0 star property
8.8 out of 10, Excellent, (745)
"Great quick stay. Most of the room looked clean. Very spacious. Did not use the couch as it had alot of stains. "
The price is ￥18,070
￥20,510 total
includes taxes & fees
May 30 - May 31
Residence Inn by Marriott Jacksonville Butler Boulevard
Tru by Hilton Jacksonville South Mandarin
Reception
Tru by Hilton Jacksonville South Mandarin
2.5 star property
8.8 out of 10, Excellent, (666)
"I like it"
The price is ￥13,109
￥14,878 total
includes taxes & fees
May 27 - May 28
Tru by Hilton Jacksonville South Mandarin
Courtyard by Marriott Jacksonville Flagler Center
Property amenity
Courtyard by Marriott Jacksonville Flagler Center
3.0 star property
8.8 out of 10, Excellent, (908)
"Staff was very accommodating, and the facility was well kept."
The price is ￥14,488
￥16,444 total
includes taxes & fees
May 27 - May 28
Courtyard by Marriott Jacksonville Flagler Center
Hampton Inn Jacksonville-I-295 East/Baymeadows
Lobby
Hampton Inn Jacksonville-I-295 East/Baymeadows
2.5 star property
8.8 out of 10, Excellent, (1005)
"I was in room 314 and there is no curtains and because you had light shades. It was light in my room 24 seven 365."
The price is ￥15,698
￥17,817 total
includes taxes & fees
Jun 1 - Jun 2
Hampton Inn Jacksonville-I-295 East/Baymeadows
Candlewood Suites Jacksonville - Mayport, an IHG Hotel
Studio Suite, 2 Queen Beds | Down comforters, desk, laptop workspace, blackout drapes
Candlewood Suites Jacksonville - Mayport, an IHG Hotel
2.5 star property
8.8 out of 10, Excellent, (168)
"Great"
The price is ￥19,091
￥21,669 total
includes taxes & fees
May 26 - May 27
Candlewood Suites Jacksonville - Mayport, an IHG Hotel
Hampton Inn Jacksonville South/I-95 at JTB
Lobby
Hampton Inn Jacksonville South/I-95 at JTB
2.5 star property
8.8 out of 10, Excellent, (1003)
"It was a clean, comfortable room as to be expected. We stayed here on the way to our destination and booked again on the way back soley because the breakfast was so good. Lol."
The price is ￥18,405
￥20,889 total
includes taxes & fees
Jun 9 - Jun 10
Hampton Inn Jacksonville South/I-95 at JTB
Courtyard by Marriott Jacksonville Butler Boulevard
Terrace/patio
Courtyard by Marriott Jacksonville Butler Boulevard
3.0 star property
8.6 out of 10, Excellent, (515)
"Check in was fast and easy, safe family environment."
The price is ￥16,684
￥18,936 total
includes taxes & fees
Jun 2 - Jun 3
Courtyard by Marriott Jacksonville Butler Boulevard
Holiday Inn Express Hotel & Suites Jacksonville - South, an IHG Hotel
Outdoor pool
Holiday Inn Express Hotel & Suites Jacksonville - South, an IHG Hotel
2.5 star property
8.6 out of 10, Excellent, (688)
"We liked that we weren’t far from eating and shopping establishments, but the hotel was more private. Not in a busy area. Staff was helpful! Breakfast was good! "
The price is ￥13,241
￥15,028 total
includes taxes & fees
Jun 2 - Jun 3
Holiday Inn Express Hotel & Suites Jacksonville - South, an IHG Hotel
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
Terrace/patio
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
3.0 star property
8.4 out of 10, Very Good, (639)
"NICE PROPERTY "
The price is ￥25,081
￥28,466 total
includes taxes & fees
May 25 - May 26
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
Holiday Inn Express and Suites Jacksonville East, an IHG Hotel
Premium bedding, pillowtop beds, in-room safe, desk
Holiday Inn Express and Suites Jacksonville East, an IHG Hotel
2.5 star property
8.4 out of 10, Very Good, (1003)
"The older guy that checked us in was awesome . Very helpful ."
The price is ￥15,578
￥17,680 total
includes taxes & fees
Jun 2 - Jun 3
Holiday Inn Express and Suites Jacksonville East, an IHG Hotel
Don't see what you're looking for?
See all available properties in Mayo Clinic Florida
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What's the area like around Mayo Clinic Florida?

Mayo Clinic Florida is located in a welcoming area of Jacksonville known for its beautiful beaches and surfing. If you're looking for a convenient place to stay, check out the 26 hotels and other accommodations you'll find within a mile.

What's the best place to stay close to Mayo Clinic Florida?

Adjacent to Mayo Clinic Florida, Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Another good choice is Residence Inn By Marriott Jacksonville - Mayo Clinic Area, located just 0.7 mi (1.1 km) away.

How many hotels will I find near Mayo Clinic Florida?

Expedia has 26 hotels and other accommodations within a mile from Mayo Clinic Florida.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Florida, will I receive a refund?

Yes, you'll find most hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Add your dates and click on "Search", then you can filter by "fully refundable" to review the best deals available near Mayo Clinic Florida.

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Florida?

To access more information about picking new dates or cancelling your stay near Mayo Clinic Florida, head over to our customer service page.

What can I see and do near Mayo Clinic Florida?

You can enjoy live performances at Wilson Center For the Arts and Players by the Sea. Spend some time exploring the natural beauty of Huguenot Park, Oceanfront Park, and South Beach Park and Sunshine Playground. Lounge by the water at Northeast Florida Beaches and Ponte Vedra Beach.