
Find hotels near Mayo Clinic Florida, Jacksonville from ¥19,992
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for Mayo Clinic Florida hotels

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
Residence Inn By Marriott Jacksonville - Mayo Clinic Area1.1 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (480 reviews)
The price is ¥25,410
¥28,841 total
includes taxes & fees
Apr 19 - Apr 20

Hilton Jacksonville At Mayo Clinic
Hilton Jacksonville At Mayo Clinic0.8 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (189 reviews)
The price is ¥29,947
¥33,989 total
includes taxes & fees
Apr 19 - Apr 20

TownePlace Suites by Marriott Jacksonville East
TownePlace Suites by Marriott Jacksonville EastGolden Glades - The Woods, 3.1 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (598 reviews)
The price is ¥19,657
¥22,310 total
includes taxes & fees
Apr 12 - Apr 13

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo ClinicGolden Glades - The Woods, 3.1 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,003 reviews)
The price is ¥17,615
¥19,992 total
includes taxes & fees
Apr 19 - Apr 20

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG2.6 km from Mayo Clinic Florida
8.8 out of 10, Excellent, (1,006 reviews)
The price is ¥17,899
¥20,315 total
includes taxes & fees
Apr 12 - Apr 13

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches0.4 km from Mayo Clinic Florida
8.4 out of 10, Very Good, (768 reviews)
The price is ¥25,810
¥29,295 total
includes taxes & fees
Apr 18 - Apr 19

Holiday Inn Express Jacksonville Beach by IHG
Holiday Inn Express Jacksonville Beach by IHG4.6 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,006 reviews)
The price is ¥19,497
¥22,129 total
includes taxes & fees
Apr 26 - Apr 27

The Hotel Palms Poolside
The Hotel Palms Poolside7.8 km from Mayo Clinic Florida
9.8 out of 10, Exceptional, (457 reviews)
The price is ¥28,860
¥32,756 total
includes taxes & fees
Apr 27 - Apr 28

Element Jacksonville Beach
Element Jacksonville Beach5.4 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (543 reviews)
The price is ¥28,446
¥32,286 total
includes taxes & fees
Apr 12 - Apr 13

Margaritaville Jacksonville Beach
Margaritaville Jacksonville Beach5.9 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (3,809 reviews)
The price is ¥27,184
¥30,855 total
includes taxes & fees
Apr 12 - Apr 13

The Hotel Palms Courtyard
The Hotel Palms Courtyard7.8 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (294 reviews)
The price is ¥30,295
¥34,385 total
includes taxes & fees
Apr 14 - Apr 15

Hampton Inn Jacksonville Beach/Oceanfront
Hampton Inn Jacksonville Beach/Oceanfront6.3 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (2,656 reviews)
The price is ¥31,320
¥35,548 total
includes taxes & fees
Apr 14 - Apr 15

Hyatt Place Jacksonville / St. Johns Town Center
Hyatt Place Jacksonville / St. Johns Town CenterSouthside, 8.6 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,002 reviews)
The price is ¥18,218
¥20,677 total
includes taxes & fees
Apr 19 - Apr 20

Best Western Oceanfront
Best Western Oceanfront5.7 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,008 reviews)
The price is ¥23,906
¥27,133 total
includes taxes & fees
Apr 29 - Apr 30

AC Hotel Jacksonville St Johns Town Center
AC Hotel Jacksonville St Johns Town CenterSouthside, 8.1 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (185 reviews)
The price is ¥28,606
¥32,469 total
includes taxes & fees
Apr 4 - Apr 5

Tru By Hilton Jacksonville St Johns Town Center
Tru By Hilton Jacksonville St Johns Town CenterSouthside, 8.7 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (877 reviews)
The price is ¥19,548
¥22,188 total
includes taxes & fees
Apr 5 - Apr 6

Holiday Inn Express & Suites Jacksonville - Town Center by IHG
Holiday Inn Express & Suites Jacksonville - Town Center by IHGSouthside, 7.7 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (1,005 reviews)
The price is ¥19,558
¥22,198 total
includes taxes & fees
Apr 20 - Apr 21

Four Points by Sheraton Jacksonville Beachfront
Four Points by Sheraton Jacksonville Beachfront5.6 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,002 reviews)
The price is ¥35,158
¥39,904 total
includes taxes & fees
Apr 26 - Apr 27

Springhill Suites By Marriott Jacksonville Beach Oceanfront
Springhill Suites By Marriott Jacksonville Beach Oceanfront5.8 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (657 reviews)
The price is ¥30,524
¥34,646 total
includes taxes & fees
Apr 5 - Apr 6

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass8.5 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,004 reviews)
The price is ¥27,875
¥31,080 total
includes taxes & fees
Apr 5 - Apr 6
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Compare popular hotels close to Mayo Clinic Florida
Property | Star rating | Guest rating | Breakfast included | Pool | Spa | Pet friendly | WiFi included | |
|---|---|---|---|---|---|---|---|---|
![]() Residence Inn By Marriott Jacksonville - Mayo Clinic Area | 9.4 Exceptional 480 reviews | View | ||||||
![]() Hilton Jacksonville At Mayo Clinic | 9.4 Exceptional 189 reviews | View | ||||||
![]() TownePlace Suites by Marriott Jacksonville East | 9.2 Wonderful 598 reviews | View | ||||||
![]() Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic | 9.0 Wonderful 1,003 reviews | View | ||||||
![]() Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG | 8.8 Excellent 1,006 reviews | View |
Top Mayo Clinic Florida Hotel Reviews

Hilton Jacksonville At Mayo Clinic
10/10 Excellent
Hotels near other Mayo Clinic Florida attractions
Frequently asked questions
Explore a world of travel with Expedia
- Hotels near Mayport Naval Station
- Hotels near Jacksonville University
- Hotels near South Ponte Vedra Beach
- Atlantic Beach Hotels
- Scuba Diving Hotels in Jacksonville
- Hotels near Jacksonville Naval Air Station
- Cabin Rentals in Jacksonville
- Resorts & Hotels with Spas in Jacksonville
- Southbank Hotels
- Cheap Hotels in Jacksonville Beach
- Beach Hotels in Jacksonville Coast
- Apartments in Jacksonville
- Pousadas in Neptune Beach
- Hotels near Omni Amelia Island Resort Golf
- Cheap Hotels in Phoenix
- All-Inclusive Hotel Hotels in Dolphin's Cove
- Hotels with smoking rooms in Northside
- Beach Hotels in Amelia Island
- Resorts & Hotels with Spas in Jacksonville Coast
- Hotels with WiFi in Jacksonville
- All-Inclusive Hotel Hotels in Southeast Jacksonville
- Vacation Homes in Jacksonville Beach
- Palaces in Jacksonville
- Cruise Ships in Jacksonville
- Historic Hotels in Amelia Island
- Inns in Green Cove Springs
- Cabin Rentals in Jacksonville Beach
- Arlington Hotels
- All-Inclusive Hotel Hotels in American Beach
- Town Houses in Ponte Vedra Beach
- Resorts in Neptune Beach
- Vacation Homes in Fleming Island
- Hotels near Metropolitan Park
- Romantic Hotels in Jacksonville
- Cheap Hotels in Downtown Jacksonville
- Hotels with smoking rooms in Mandarin
- Jacksonville Beach Hotels
- Aparthotels in Jacksonville Beach
- Cheap Hotels in Jacksonville
- Beach Hotels in Ponte Vedra Beach
- Pet-Friendly Hotels in Jacksonville Beach
- Jacksonville Hotels
- Hotels near Riverside Park
- Pet-Friendly Hotels in Orange Park
- Hotels near Eagle Harbor Golf Club
- Hotels near Jacksonville Station
- Pet-Friendly Hotels in Jacksonville
- Hotels near Jacksonville Executive at Craig
- B&B in St. Johns
- Resorts in Jacksonville Beach
- Beach Hotels in Atlantic Beach
- Hotels near Mickler Beach
- Orange Park Hotels
- Pet-Friendly Hotels in Downtown Jacksonville
- Hotels near St. Johns Town Center
- Villas in Ponte Vedra Beach
- Farmstay in Jacksonville
- Hotels with Early Check-in in American Beach
- Hotels near Atlantic Beach
- Hotels with Waterslides in American Beach
- Residences in Ponte Vedra
- Beach Hotels in Downtown Jacksonville
- Downtown Jacksonville Hotels
- Condo Rentals in Amelia Island
- Beach Hotels in Jacksonville
- Riverside Hotels
- Resorts & Hotels with Spas in Southeast Jacksonville
- Cheap Hotels in Southbank
- Hotels near Sawgrass Village
- Mayport Hotels
- Inns in Jacksonville
- Hotels with a Pool in Amelia Island
- Boutique Hotels in San Marco
- Hotels near TPC Sawgrass
- Motels in Jacksonville Beach
- Inns in Jacksonville Beach
- Baymeadows Hotels
- Rv Parks in Jacksonville
- San Jose Hotels
- Resorts & Hotels with Spas in Green Cove Springs
- Hotel with a Concierge Hotels in Amelia Island
- Hotels near Daily's Place
- Resorts in Ponte Vedra Beach
- Resorts in Ponte Vedra
- Residences in Neptune Beach
- Historic Hotels in Orange Park
- Luxury Hotels in Phoenix
- Luxury Hotels in Downtown Jacksonville
- Beach Hotels in American Beach
- Cottages in Atlantic Beach
- Deerwood Hotels
- Hotels near Adventure Landing
- Phoenix Hotels
- Luxury Hotels in Jacksonville
- Hotels with Early Check-in in Southbank








































































