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Our top choices for Lyon hotels

A two-story brick building with large windows and a green door, featuring outdoor seating and a signboard.
A window with the text "TRAVELERS HOTEL" and a reflection of a bar area with stools and a counter.
A dining area with a table and four chairs, a potted plant, and a lamp.
A spacious lobby with a green door, a beige sofa, a wooden coffee table, and a large window offering a view of the outside.

1. Travelers Hotel

Travelers Hotel
Clarksdale
United States
Reade
￥23,384
￥25,489 total
includes taxes & fees
Oct 13 - Oct 14
Travelers Hotel
A hotel dining area with a large wooden table, multiple chairs, a television, and wall-mounted lights.
A Hampton Inn with a modern beige facade, a flag, and a covered entrance.
A reception desk with a wooden finish, a framed welcome sign, and a lamp.
A rectangular swimming pool with a blue interior, surrounded by a brick border and a metal railing.

2. Hampton Inn Clarksdale

Hampton Inn Clarksdale
Clarksdale
United States
Judy
￥20,526
￥22,372 total
includes taxes & fees
Nov 1 - Nov 2
Hampton Inn Clarksdale
A lobby with patterned carpet, two sofas, a round coffee table, a plant, and a framed picture on the wall.
A hotel with a covered outdoor area, columns, and a clear sky.
A self-service beverage station with various drink dispensers and a refrigerator.
A fitness room with an elliptical trainer, a treadmill, and a stationary bike.

3. Quality Inn Clarksdale

Quality Inn Clarksdale
Clarksdale
United States
Blu
￥12,165
￥13,260 total
includes taxes & fees
Oct 22 - Oct 23
Quality Inn Clarksdale
A spacious living area with a sofa, armchairs, and a coffee table. Large windows with curtains provide a view of the outdoors.
A compact black refrigerator with a microwave on top, a small wooden table, and a potted plant.
A hotel reception area with a reception desk, a framed picture, a door with a keypad, and a blue mat at the entrance.
A hotel room with two beds, a desk with a computer, a chair, a television, and two lamps.

4. Americas Best Value Inn & Suites Clarksdale

Americas Best Value Inn & Suites Clarksdale
Clarksdale
United States
Darren
￥12,588
￥13,721 total
includes taxes & fees
Oct 2 - Oct 3
Americas Best Value Inn & Suites Clarksdale
A bar area with wooden bar stools and shelves with bottles and glasses.
A hallway with a white wall, wooden floor, a sofa, a lamp, and a rug.
A shower area with three white shower curtains tied to a central rod, beige tiled walls, and a tiled floor.
A modern lounge area with a flat-screen TV, ceiling fans, and guitars on the wall.

5. Auberge Clarksdale Blues Hostel

Auberge Clarksdale Blues Hostel
Clarksdale
United States
Brian
￥17,449
￥19,020 total
includes taxes & fees
Oct 2 - Oct 3
Auberge Clarksdale Blues Hostel
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Top Lyon Hotel Reviews

The Sunflower Penthouse on the River in Clarksdale

The Sunflower Penthouse on the River in Clarksdale

8/10 Good
"Great place to stay."
Mark W. 2-night trip
Posted 4 days ago
The Sunflower Penthouse on the River in Clarksdale
Quality Inn Clarksdale

Quality Inn Clarksdale

10/10 Excellent
"Nice place overall, clean and quiet and the front desk was very nice…"
Obie 1-night trip
Posted 4 days ago
Quality Inn Clarksdale
Hampton Inn Clarksdale

Hampton Inn Clarksdale

10/10 Excellent
"Staff was so helpful and very friendly and personable."
Jimmy 2-night trip
Posted 11 days ago
Hampton Inn Clarksdale
Only a mile from historic downtown Clarksdale!

Only a mile from historic downtown Clarksdale!

10/10 Excellent
"Nice & quiet place to stay. Perfect for our anniversary weekend."
Jeni H. 1-night trip
Posted 11 days ago
Only a mile from historic downtown Clarksdale!
Get to BLUES-in' at Rusty's Roost, adjacent to downtown Clarksdale, MS

Get to BLUES-in' at Rusty's Roost, adjacent to downtown Clarksdale, MS

10/10 Excellent
"Very clean, very nice and comfortable, very pet friendly, washer and dryer worked well, host was very attentive, and property is very close to everything in clarksdale!!Very pleased!!"
STEPHANIE P. 3-night trip
Posted 1 month ago
Get to BLUES-in' at Rusty's Roost, adjacent to downtown Clarksdale, MS
Sunset Log Cabin

Sunset Log Cabin

10/10 Excellent
"Libby is a very professional and responsive host. The place was perfect for my needs, allowed my dog, easy to get to town, yet also a bit on outskirts so not surrounded by hustle and bustle. Pleasant, rustic vibe, relaxing, and would definitely stay again."
Matt S. 2-night trip
Posted 1 month ago
Sunset Log Cabin
Casa D’Amore!!!! Adorable home less than 1/2 mile from downtown Clarksdale

Casa D’Amore!!!! Adorable home less than 1/2 mile from downtown Clarksdale

10/10 Excellent
"My go to place to stay when I visit Clarksdale. Has everything you need. Very quiet street and close to everything downtown."
KENNETH M. 5-night trip
Posted 2 months ago
Casa D’Amore!!!! Adorable home less than 1/2 mile from downtown Clarksdale
The Governors Mansion in Clarksdale Mississippi. A Step Back in Time

The Governors Mansion in Clarksdale Mississippi. A Step Back in Time

10/10 Excellent
"There was a total of 15 of us, Siblings with our children. We had a great time with thoroughly enjoyed the pool and all the laughter just hanging out playing games and eating meals together. A great place for a lot of people."
Marietta M. 2-night trip
Posted 2 months ago
The Governors Mansion in Clarksdale Mississippi. A Step Back in Time
Cottage on riverbank one mile from Clarksdale in gated community

Cottage on riverbank one mile from Clarksdale in gated community

10/10 Excellent
"The property was very clean, comfortable and check in was so easy, the hospitality was amazing, we really enjoyed ourselves and will be visiting again!!!"
Bridget I. 3-night trip
Posted 3 months ago
Cottage on riverbank one mile from Clarksdale in gated community

More cheap stays in Lyon

Quality Inn Clarksdale

Quality Inn Clarksdale

818 South State Street Clarksdale MS
￥12,165
￥13,260 total
Oct 22 - Oct 23
includes taxes & fees
7.2/10 Good! (780 reviews)
Quality Inn Clarksdale
Americas Best Value Inn & Suites Clarksdale

Americas Best Value Inn & Suites Clarksdale

350 South State Street Clarksdale MS
￥12,588
￥13,721 total
Oct 2 - Oct 3
includes taxes & fees
6/10 (432 reviews)
Americas Best Value Inn & Suites Clarksdale
Auberge Clarksdale Blues Hostel

Auberge Clarksdale Blues Hostel

164 Delta Ave Clarksdale MS
￥17,449
￥19,020 total
Oct 2 - Oct 3
includes taxes & fees
9.6/10 Exceptional! (110 reviews)
Auberge Clarksdale Blues Hostel
Hampton Inn Clarksdale

Hampton Inn Clarksdale

15000 New Africa Rd Clarksdale MS
￥20,526
￥22,372 total
Nov 1 - Nov 2
includes taxes & fees
8.2/10 Very Good! (411 reviews)
Hampton Inn Clarksdale
Travelers Hotel

Travelers Hotel

212 3rd St Clarksdale MS
￥23,384
￥25,489 total
Oct 13 - Oct 14
includes taxes & fees
Travelers Hotel
High Cotton Condos

High Cotton Condos

249 Delta Ave Clarksdale MS
Get rates
8.8/10 Excellent! (6 reviews)
High Cotton Condos

Frequently asked questions

What's the best place for a stay in Lyon?
Quality Inn Clarksdale, located 3.2 mi (5.2 km) from the heart of Lyon, is a top choice for your stay based on our traveler data. Other good options for your trip to the area are Hampton Inn Clarksdale and Travelers Hotel. See all available top hotels, or vacation rentals in Lyon.
What are some of the best vacation rentals that Lyon has to offer?
Casa D'Amore!!!! Adorable home less than 1/2 mile from downtown Clarksdale: This vacation home rental outside of Lyon is equipped with a fireplace, air-conditioning, and laundry facilities to help you feel comfortable during your stay. Kitchen amenities include a fridge, a stovetop, and a microwave. See all vacation rentals in Lyon.
If I need to cancel my hotel reservation in Lyon, will I receive a refund?
Yes! The majority of hotel reservations are fully refundable if cancelled prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, you might be able to still cancel and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Lyon.
Where can I learn more about changing or cancelling my trip to Lyon?
For additional details about updating your trip to Lyon or cancelling it, head over to our customer service page.
What is staying in Lyon like?
Travelers to Lyon will find plenty to explore and enjoy. There are 31 hotels and other accommodations in the surrounding area. Find out more about Lyon.
What should I do while I'm visiting Lyon?
Places to visit in the wider area include Delta Blues Museum, Ground Zero Blues Club, and Rock N' Roll & Blues Heritage Museum. You'll also find The Crossroads and The Holy Moly Theatre in the area. Check out what more to see and do in Expedia's Lyon guide.
What's the seasonal weather like in Lyon?
The hottest months are usually July and August with an average temp of 79°F, while the coldest months are January and February with an average of 47°F. The rainiest months in Lyon are April, March, May, and December, with each month seeing an average of 7 inches of rainfall.

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