Find hotels in Lake Nona Medical City, Orlando from ￥8,428

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Nov 21 - Nov 22
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Discover 27,505 Lake Nona Medical City hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Lounge
Aloft Orlando Lake Nona

Aloft Orlando Lake Nona

3.0 star property
Lake Nona Medical City
9.8 out of 10, Exceptional, (248)
"Beautiful hotel and excellent location. "
United States
Samue
The price is ￥17,945
￥20,187 total
includes taxes & fees
Nov 30 - Dec 1
Aloft Orlando Lake Nona
Outdoor pool
Courtyard Orlando Lake Nona

Courtyard Orlando Lake Nona

3.0 star property
Lake Nona Medical City
9.6 out of 10, Exceptional, (584)
"Great stay"
United States
Romulo
The price is ￥21,200
￥24,088 total
includes taxes & fees
Nov 27 - Nov 28
Courtyard Orlando Lake Nona
Outdoor pool
Residence Inn Orlando Lake Nona

Residence Inn Orlando Lake Nona

3.0 star property
Lake Nona Medical City
9.6 out of 10, Exceptional, (324)
"Good hotel "
China
lily
The price is ￥26,760
￥30,406 total
includes taxes & fees
Dec 21 - Dec 22
Residence Inn Orlando Lake Nona
Lobby
La Quinta Inn & Suites by Wyndham Orlando UCF

La Quinta Inn & Suites by Wyndham Orlando UCF

3.0 star property
25.4 km from Lake Nona Medical City
8.6 out of 10, Excellent, (2673)
"Great location and friendly staff!"
United States
Loren
The price is ￥14,584
￥16,407 total
includes taxes & fees
Nov 24 - Nov 25
La Quinta Inn & Suites by Wyndham Orlando UCF
Terrace/patio
The Delaney Hotel

The Delaney Hotel

3.5 star property
South Orange, 20.2 km from Lake Nona Medical City
9.6 out of 10, Exceptional, (1004)
"All around wonderful stay"
United States
Caleb
The Delaney Hotel
Premium bedding, in-room safe, desk, blackout drapes
Ramada by Wyndham Suites Orlando Airport

Ramada by Wyndham Suites Orlando Airport

3.0 star property
Airport North, 10.4 km from Lake Nona Medical City
8.2 out of 10, Very Good, (5103)
"Great place to stay close to airport "
United States
Rebekah
The price is ￥14,016
￥15,770 total
includes taxes & fees
Dec 17 - Dec 18
Ramada by Wyndham Suites Orlando Airport
Pillowtop beds, in-room safe, desk, blackout drapes
Wingate by Wyndham - Orlando International Airport

Wingate by Wyndham - Orlando International Airport

3.0 star property
Airport North, 11 km from Lake Nona Medical City
8.8 out of 10, Excellent, (3709)
"Good room, good breakfast and convenient to the airport."
United States
Mark
The price is ￥12,711
￥14,301 total
includes taxes & fees
Nov 24 - Nov 25
Wingate by Wyndham - Orlando International Airport
Exterior
Country Inn & Suites by Radisson, Orlando Airport, FL

Country Inn & Suites by Radisson, Orlando Airport, FL

3.0 star property
Airport North, 11 km from Lake Nona Medical City
7.8 out of 10, Good, (4241)
"We had a great stay. The room, breakfast, and staff were great. "
United States
Jeidyn
The price is ￥11,031
￥12,409 total
includes taxes & fees
Dec 16 - Dec 17
Country Inn & Suites by Radisson, Orlando Airport, FL
6 outdoor pools, free cabanas, pool umbrellas
Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando

Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando

4.0 star property
22.5 km from Lake Nona Medical City
9.2 out of 10, Wonderful, (3956)
"Nice place to stay for family. "
United States
Niketan Chhaganbhai
The price is ￥15,615
￥17,568 total
includes taxes & fees
Dec 16 - Dec 17
Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando
Property grounds
SPOT X Hotel Orlando/Intl Dr by The Red Collection

SPOT X Hotel Orlando/Intl Dr by The Red Collection

3.0 star property
21 km from Lake Nona Medical City
8.6 out of 10, Excellent, (2890)
"One of the best hotel!"
United States
Li
The price is ￥9,805
￥13,863 total
includes taxes & fees
Nov 25 - Nov 26
SPOT X Hotel Orlando/Intl Dr by The Red Collection
Lobby lounge
Aloft Orlando Lake Buena Vista

Aloft Orlando Lake Buena Vista

3.0 star property
21.7 km from Lake Nona Medical City
8.8 out of 10, Excellent, (1871)
"Great stay"
United States
Ramprasad
The price is ￥11,019
￥12,398 total
includes taxes & fees
Nov 24 - Nov 25
Aloft Orlando Lake Buena Vista
Outdoor pool, sun loungers
Wyndham Garden Orlando Airport

Wyndham Garden Orlando Airport

3.0 star property
Belle Isle, 11.9 km from Lake Nona Medical City
9.0 out of 10, Wonderful, (3969)
"Would stay again! "
United States
Matthew
The price is ￥11,900
￥13,389 total
includes taxes & fees
Dec 15 - Dec 16
Wyndham Garden Orlando Airport
Outdoor pool, pool umbrellas, sun loungers
Kompose Boutique Resort at Theme Parks

Kompose Boutique Resort at Theme Parks

3.0 star property
30.8 km from Lake Nona Medical City
9.4 out of 10, Exceptional, (1808)
"Great stay."
United States
Jasmin
The price is ￥7,475
￥14,736 total
includes taxes & fees
Dec 1 - Dec 2
Kompose Boutique Resort at Theme Parks
Outdoor pool
DoubleTree by Hilton at the Entrance to Universal Orlando

DoubleTree by Hilton at the Entrance to Universal Orlando

4.0 star property
Florida Center, 21.7 km from Lake Nona Medical City
8.4 out of 10, Very Good, (6872)
"Great stay "
United States
Anthony
The price is ￥15,324
￥17,240 total
includes taxes & fees
Dec 17 - Dec 18
DoubleTree by Hilton at the Entrance to Universal Orlando
Outdoor pool, open 9 AM to 10 PM, sun loungers
Orlando Palms Hotel

Orlando Palms Hotel

2.5 star property
14.9 km from Lake Nona Medical City
7.6 out of 10, Good, (2204)
"Great stay"
United States
Christian Mitchel
The price is ￥5,822
￥8,428 total
includes taxes & fees
Dec 10 - Dec 11
Orlando Palms Hotel
Meeting facility
Hampton Inn & Suites Orlando Intl Dr N

Hampton Inn & Suites Orlando Intl Dr N

2.5 star property
International Drive District, 21.6 km from Lake Nona Medical City
9.2 out of 10, Wonderful, (1046)
"Second time staying at this hotel and loved it great hotel for family and close to the main attractions "
United States
Kadeisha
The price is ￥13,726
￥15,441 total
includes taxes & fees
Dec 21 - Dec 22
Hampton Inn & Suites Orlando Intl Dr N
Property entrance
Holiday Inn Express & Suites Orlando - Lake Buena Vista by IHG

Holiday Inn Express & Suites Orlando - Lake Buena Vista by IHG

3.0 star property
21.6 km from Lake Nona Medical City
8.8 out of 10, Excellent, (2240)
"Every thing was good, it was an enjoyable stay ! "
United States
Cheyenne
The price is ￥12,593
￥14,167 total
includes taxes & fees
Nov 23 - Nov 24
Holiday Inn Express & Suites Orlando - Lake Buena Vista by IHG
4 outdoor pools, open 5:30 AM to midnight, cabanas (surcharge)
Rosen Shingle Creek

Rosen Shingle Creek

4.5 star property
16.9 km from Lake Nona Medical City
9.4 out of 10, Exceptional, (4253)
"Great resort "
United States
Camille
The price is ￥14,879
￥16,738 total
includes taxes & fees
Dec 19 - Dec 20
Rosen Shingle Creek
View from property
Avanti International Resort

Avanti International Resort

4.0 star property
International Drive District, 20.8 km from Lake Nona Medical City
7.8 out of 10, Good, (4232)
"Great room, helpful cleaners, wonderful pool, great location"
United Kingdom
Gabrielle
The price is ￥8,936
￥13,242 total
includes taxes & fees
Dec 14 - Dec 15
Avanti International Resort
Outdoor pool, free cabanas, pool umbrellas
Holiday Inn & Suites Orlando I-Drive Theme Parks by IHG

Holiday Inn & Suites Orlando I-Drive Theme Parks by IHG

3.0 star property
20.9 km from Lake Nona Medical City
9.0 out of 10, Wonderful, (1656)
"Good place to stay "
United States
Arturo
The price is ￥13,097
￥14,735 total
includes taxes & fees
Dec 14 - Dec 15
Holiday Inn & Suites Orlando I-Drive Theme Parks by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Lake Nona Medical City

Find the best Lake Nona Medical City areas and neighborhoods for the activities you enjoy most. Learn more about Lake Nona Medical City
Learn more about Lake Nona Medical City
International Drive showing landscape views

International Drive District

Adventure activities, iconic attractions, shopping and world-class dining destinations make this famous street one of Orlando’s most popular tourist attractions.

Magic Kingdom® Park showing rides and interior views as well as a couple
Photo by ©Disney
Open Photo by ©Disney

Bay Lake

Home to all four Walt Disney World Resort theme parks and one water park, this city offers endless entertainment, including Disney's Fort Wilderness Resort & Campground and Magnolia and Palm Golf Courses.

Downtown Orlando

Downtown Orlando

Orlando's historic core boasts art galleries, retail, restaurants, and nightclubs, with attractions like Lake Eola Park, Linton E. Allen Memorial Fountain, and performing arts theaters, all accessible via public transportation.

Universal Studios Orlando featuring signage, a city and night scenes

Florida Center

While visiting Florida Center, you might make a stop by sights like Universal Orlando Resort and Universal Studios Florida.

Champions Gate

Abundant dining options and pristine golf courses are well-reviewed features of Champions Gate. Make a stop by top sights like ChampionsGate Golf Club while you're exploring the area.

Top Lake Nona Medical City Hotel Reviews

Wyndham I-Drive Avanti Resort & Conference Center

Wyndham I-Drive Avanti Resort & Conference Center

10/10 Excellent
"Convenient location!"
Hailey Ann 4-night trip
Posted 1 day ago
Wyndham I-Drive Avanti Resort & Conference Center

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Frequently asked questions

What's it like in Lake Nona Medical City?
Lake Nona Medical City is a neighborhood that travelers like for its restaurants.
What's a favorite place to stay in Lake Nona Medical City?
Based on Expedia customer reviews, Aloft Orlando Lake Nona is the highest ranked property in Lake Nona Medical City. This hotel offers a restaurant and an outdoor pool. Other favorite options in the area include Residence Inn Orlando Lake Nona and Courtyard Orlando Lake Nona.
How many hotels are there in Lake Nona Medical City?
Expedia has 5 Lake Nona Medical City hotels and other accommodations, and one might make a good home base for venturing out into the greater Orlando area.
If I need to cancel my hotel reservation in Lake Nona Medical City, will I receive a refund?
Yes, the majority of hotel reservations are fully refundable if cancelled prior to the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a non-refundable reservation, you might still have the option to cancel and get a refund within 24 hours of your booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to review the best options available in Lake Nona Medical City.
Where can I learn more about changing or cancelling my trip to Lake Nona Medical City?
For more information about changing or cancelling your trip to Lake Nona Medical City, click here.
What is there to do around this Orlando neighborhood?
Eagle Creek Golf Club, USTA National Campus, and Austin-Tindall Regional Park are just a few of the places to visit in and around Lake Nona Medical City. When you're sightseeing around the area, Lake Hart and Kissimmee Bay Country Club are a couple of other sights to visit.