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Compare 1,355 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Our top choices for Keowee hotels

Tru by Hilton Seneca Clemson

2.5 star property
9.2 out of 10, Wonderful, (761)
"Staff and property were top-notch! "
The price is ¥16,662
¥18,329 total
includes taxes & fees
Aug 31 - Sep 1
Tru by Hilton Seneca Clemson

Woodspring Suites Anderson North I-85

2.5 star property
6.4 out of 10, (22)
"Very nice and clean property. Staff was so nice and helpful. Made check in so easy"
The price is ¥11,718
¥13,007 total
includes taxes & fees
Aug 24 - Aug 25
Woodspring Suites Anderson North I-85

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

2.5 star property
9.0 out of 10, Wonderful, (559)
"My daughter and I stayed at the property for one night, as we traveled back home. The room was wonderfully clean, the beds comfortable, and the front desk staff was warm and accommodating. I noticed that the hotel even offered board games to play with friends or family. "
The price is ¥15,278
¥16,960 total
includes taxes & fees
Aug 31 - Sep 1
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Fairfield Inn & Suites Seneca Clemson Univ Area

2.5 star property
9.4 out of 10, Exceptional, (184)
"Beautiful clean hotel. Staff was very welcoming. Breakfast area was very clean with many options. The river view is so beautiful. "
The price is ¥18,955
¥20,852 total
includes taxes & fees
Sep 1 - Sep 2
Fairfield Inn & Suites Seneca Clemson Univ Area

Baymont by Wyndham Anderson Clemson

2.5 star property
7.0 out of 10, Good, (812)
"Excellent stay "
The price is ¥10,086
¥11,195 total
includes taxes & fees
Sep 12 - Sep 13
Baymont by Wyndham Anderson Clemson

Lakeside Lodge Clemson

2.5 star property
9.0 out of 10, Wonderful, (998)
"Great place to stay in Clemson"
The price is ¥16,016
¥20,081 total
includes taxes & fees
Aug 31 - Sep 1
Lakeside Lodge Clemson

Inn @ Clemson

2.5 star property
8.0 out of 10, Very Good, (1002)
"It was very clean. A nice place to stay "
The price is ¥12,425
¥13,790 total
includes taxes & fees
Sep 1 - Sep 2
Inn @ Clemson

Quality Inn Clemson near University

2.5 star property
7.0 out of 10, Good, (863)
"Great customer service "
The price is ¥8,952
¥9,937 total
includes taxes & fees
Aug 24 - Aug 25
Quality Inn Clemson near University

Hampton Inn & Suites Seneca-Clemson Area

2.5 star property
9.4 out of 10, Exceptional, (629)
"The staff were very friendly and helpful. The room was clean and the breakfast was great!"
The price is ¥17,986
¥19,785 total
includes taxes & fees
Aug 24 - Aug 25
Hampton Inn & Suites Seneca-Clemson Area

Days Inn by Wyndham Seneca / Clemson Area

2.0 star property
6.8 out of 10, (693)
"The property was near the area that I needed to be in. It has ample shops and restaurants in the area "
The price is ¥10,591
¥11,650 total
includes taxes & fees
Sep 8 - Sep 9
Days Inn by Wyndham Seneca / Clemson Area

Best Western Plus Clemson Hotel & Conference Center

2.5 star property
8.2 out of 10, Very Good, (1007)
"The hotel was very quiet, clean and staff was very friendly!"
The price is ¥15,634
¥17,354 total
includes taxes & fees
Sep 3 - Sep 4
Best Western Plus Clemson Hotel & Conference Center

Clemson University's James F. Martin Inn

3.0 star property
9.6 out of 10, Exceptional, (924)
"Terrific Place to stay"
The price is ¥21,894
¥24,302 total
includes taxes & fees
Aug 31 - Sep 1
Clemson University's James F. Martin Inn

Comfort Inn & Suites Clemson - University Area

2.5 star property
8.2 out of 10, Very Good, (1003)
"Awesome place to stay"
The price is ¥14,988
¥16,636 total
includes taxes & fees
Aug 31 - Sep 1
Comfort Inn & Suites Clemson - University Area

The Shepherd Hotel Downtown Clemson

4.0 star property
9.8 out of 10, Exceptional, (665)
"Exceptional property and amenities, great for a quick trip or an extended stay. We highly recommend The Shepherd Hotel for any occasion."
The price is ¥26,302
¥29,195 total
includes taxes & fees
Sep 1 - Sep 2
The Shepherd Hotel Downtown Clemson

Hilton Garden Inn Anderson

3.0 star property
9.0 out of 10, Wonderful, (640)
"Breakfast was good staff was great "
The price is ¥13,869
¥15,395 total
includes taxes & fees
Sep 14 - Sep 15
Hilton Garden Inn Anderson

Country Inn & Suites by Radisson, Anderson, SC

2.5 star property
8.4 out of 10, Very Good, (1001)
"It was a good place to stay good people "
The price is ¥16,186
¥17,965 total
includes taxes & fees
Sep 2 - Sep 3
Country Inn & Suites by Radisson, Anderson, SC

Quality Inn Seneca Clemson Area US-123

2.5 star property
8.0 out of 10, Very Good, (632)
"Ok hotel for a quick stay "
The price is ¥11,770
¥14,403 total
includes taxes & fees
Aug 31 - Sep 1
Quality Inn Seneca Clemson Area US-123

Comfort Suites Anderson-Clemson

2.5 star property
8.4 out of 10, Very Good, (995)
"RESTAURANTS, HOTEL WAS GREAT STAFF WAS AWESOME I WOULD DEFINITELY RECOMMEND. "
The price is ¥16,554
¥18,375 total
includes taxes & fees
Aug 31 - Sep 1
Comfort Suites Anderson-Clemson

Microtel Inn & Suites by Wyndham Anderson/Clemson

2.0 star property
8.2 out of 10, Very Good, (1000)
"Great place to stay!"
The price is ¥11,852
¥13,157 total
includes taxes & fees
Aug 24 - Aug 25
Microtel Inn & Suites by Wyndham Anderson/Clemson

Days Inn by Wyndham Clemson

3.5 star property
7.0 out of 10, Good, (180)
"Great place "
The price is ¥11,214
¥12,449 total
includes taxes & fees
Aug 26 - Aug 27
Days Inn by Wyndham Clemson
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Keowee

Head to sights like Lake Hartwell as you discover the local area in Keowee.

Top Keowee Hotel Reviews

Frequently asked questions

What's the best place to stay in Keowee?

Based on our traveler data, Tru by Hilton Seneca Clemson is one of the top choices for your stay. This hotel is a short 5-minute walk from Lake Hartwell, and it offers free breakfast and free parking. Other good choices for your trip to the area are Best Western Plus Clemson Hotel & Conference Center and Lakeside Lodge Clemson. See all available top hotels, or vacation rentals in Keowee.

What's the top vacation rental in Keowee?

Lake Jocassee retreat on two acres!! New hot tub, Devil’s Fork State Park: Visitors like this Keowee vacation home rental. It is located on a lake and has a balcony, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a hot tub. See all vacation rentals in Keowee.

If I need to cancel my hotel reservation in Keowee, will I receive a refund?

Yes, most room reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Keowee.

Where can I learn more about changing or cancelling my trip to Keowee?

To find more details about picking new dates or cancelling your trip to Keowee, go to https://www.expedia.com/service/.

What's the best LGBTQ-friendly accommodation in Keowee?

Tru by Hilton Seneca Clemson is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. See all available hotels listed as LGBTQ-friendly in Keowee.

What's the best pet-friendly place to stay in Keowee?

Tru by Hilton Seneca Clemson is a top hotel for people traveling with their pets, and offers a fitness center and laundry facilities for its human guests. See more pet-friendly hotel accommodations in Keowee.

What are some accommodations with pools in Keowee?

Best Western Plus Clemson Hotel & Conference Center: Hotel located near Clemson University. Offers free self parking, a seasonal outdoor pool, and a 24-hour fitness center. Lakeside Lodge Clemson and Days Inn by Wyndham Anderson are a couple of other choices that offer an onsite pool. View all hotels with pools in Keowee.

How is it to stay in Keowee?

Travelers to Keowee will find plenty to explore and enjoy. In Keowee, there are 12 hotels and other accommodations to choose from. Find out more about Keowee.

What should I do while I'm visiting Keowee?

A favorite place to visit is Lake Hartwell. You'll also find Littlejohn Coliseum and Memorial Stadium in the area. Check out what more to see and do in Expedia's Keowee guide.

What's the weather like in Keowee?

The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 46°F. Average annual precipitation for Keowee is 61 inches.