Find hotels in Irene, SD from ¥10,802

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Irene hotels

Super 8 by Wyndham Beresford

Super 8 by Wyndham Beresford
2.0 star property
Beresford
6.4 out of 10, (285)
Located near Sioux Falls Regional Airport, this motel offers free breakfast, WiFi and parking. Business travelers appreciate the friendly service and comfortable rooms, making it an ideal stopover during long journeys.

"Easy check in from online reservation last minute. Room was clean, toilet was really wobbly and breakfast was ok. "
United States
Patrick
The price is ¥9,781
¥10,631 total
includes taxes & fees
Dec 26 - Dec 27
Super 8 by Wyndham Beresford

Fairfield Inn & Suites by Marriott Yankton

Fairfield Inn & Suites by Marriott Yankton
2.5 star property
Yankton
9.4 out of 10, Exceptional, (156)
This Yankton hotel features an indoor pool and complimentary continental breakfast. Located near Fantle Memorial Park and Fox Run Plaza, guests appreciate the helpful staff and free parking at this welcoming property.

"Great place to stay "
United States
Elizabeth
The price is ¥15,286
¥16,933 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Fairfield Inn & Suites by Marriott Yankton

Yankton Inn

Yankton Inn
2.0 star property
Yankton
7.6 out of 10, Good, (273)
Near Crockett Park and Riverside Park, this business-friendly hotel offers complimentary continental breakfast, WiFi, and parking. Guests consistently praise the helpful staff, making it an ideal choice for travelers exploring Yankton.

"Clean room, low pet fee, quiet."
United States
Joseph
The price is ¥13,008
¥14,456 total
includes taxes & fees
Dec 23 - Dec 24
Yankton Inn

Lewis and Clark Resort

Lewis and Clark Resort
2.5 star property
Yankton
8.8 out of 10, Excellent, (284)
Situated on the shores of Lewis and Clark Recreation Area, this beachfront hotel offers a seasonal outdoor pool and marina access. Enjoy waterfront meals at the restaurant or refreshing drinks at the bar after exploring nearby attractions.

"Beautiful view, easy check in, and spacious accommodations! We loved our stay and can’t wait to come back!"
United States
Jessica
The price is ¥14,759
¥15,600 total
includes taxes & fees
Dec 23 - Dec 24
Lewis and Clark Resort

Econo Lodge Inn & Suites Yankton

Econo Lodge Inn & Suites Yankton
2.0 star property
Yankton
7.2 out of 10, Good, (708)
Start your day with a complimentary breakfast before exploring nearby Fox Run Plaza and Augusta Park. This peaceful hotel offers free WiFi and parking, with a morning swim or evening soak to bookend your adventures.

"Yes the room was clean staff was great"
United States
John
The price is ¥12,068
¥13,434 total
includes taxes & fees
Dec 29 - Dec 30
Econo Lodge Inn & Suites Yankton

Best Western Kelly Inn

Best Western Kelly Inn
2.5 star property
Yankton
8.0 out of 10, Very Good, (649)
Wake up to a complimentary breakfast at this Yankton hotel, where an indoor pool awaits after exploring nearby Crockett Park. Grab American cuisine at Minervas Grill and Bar, then unwind in the hot tub or fitness center.

"Very comfortable room and quiet we luv staying at your hotel oyr dog luvs it too breakfast is wonderful also luv hit tub!!!"
United States
Valerie
The price is ¥15,456
¥17,117 total
includes taxes & fees
Dec 29 - Dec 30
Best Western Kelly Inn

Holiday Inn Express & Suites Yankton by IHG

Holiday Inn Express & Suites Yankton by IHG
2.5 star property
Yankton
9.2 out of 10, Wonderful, (415)
Discover warm hospitality at this Yankton retreat with a welcoming indoor pool for morning swims. Free breakfast, WiFi and parking enhance your stay, while the fitness center keeps routines on track. Augusta Park awaits nearby.

"Yes, clean room "
United States
Evyonne
The price is ¥15,933
¥18,422 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Holiday Inn Express & Suites Yankton by IHG

Comfort Inn Yankton SD

Comfort Inn Yankton SD
2.5 star property
Yankton
8.8 out of 10, Excellent, (671)
Located near Fox Run Plaza and Golf Course, this welcoming hotel offers a complimentary continental breakfast, free WiFi, and on-site parking. Guests can maintain routines at the fitness center while enjoying the friendly service that previous visitors have praised.

"Affordable with very clean, comfortable rooms, super friendly staff and a nice breakfast. "
United States
Roberta
The price is ¥13,945
¥15,474 total
includes taxes & fees
Dec 29 - Dec 30
Comfort Inn Yankton SD
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Irene Hotel Reviews

More cheap stays in Irene

Frequently asked questions

What's the best place for a stay in Irene?
Comfort Inn Yankton SD, located 18 mi (29 km) from the heart of Irene, is a top choice for your stay based on our traveler data. Other good choices for your stay in the area are Fairfield Inn & Suites by Marriott Yankton and Best Western Kelly Inn. See all available top hotels, or vacation rentals in Irene.
What are some of the best vacation rentals that Irene has to offer?
Gavins Point Lakehouse: This vacation home rental near Irene is located in the mountains and has a fireplace, a balcony, and air-conditioning to put you at ease in your new surroundings. It has 5 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and a selection of games. See all vacation rentals in Irene.
If I need to cancel my hotel reservation in Irene, will I receive a refund?
Yes! Most room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, it might still be possible to cancel it and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Irene.
Where can I learn more about changing or cancelling my trip to Irene?
To find more details about rescheduling or cancelling your trip to Irene, go to https://www.expedia.com/service/.
What is the best hotel near Sioux Falls Regional Airport (FSD)?
AeroStay Hotel is a popular hotel, featuring free breakfast and free WiFi. It's located a short 0.1 mi (0.1 km) from Sioux Falls Regional Airport. Other good options close to the airport are Ramada by Wyndham Sioux Falls Airport Hotel & Suites and AmericInn by Wyndham Sioux Falls North.
What is staying in Irene like?
Travelers to Irene will find plenty to explore and enjoy. There are 63 hotels and other accommodations in the surrounding area. Find out more about Irene.
What should I see while I'm in Irene?
Places to visit in the wider area include Mead Museum, Fantle Memorial Park, and Crockett Park. You'll also find Lincoln Park and Aviation Park in the area. Check out what more to see and do in Expedia's Irene guide.
What's the weather like in Irene?
The hottest months are usually July and August with an average temp of 72°F, while the coldest months are January and February with an average of 26°F. The snowiest months in Irene are January, December, October, and March, with each month seeing an average of 8 inches of snowfall.