A river with a bridge, a town, and a forested hillside.

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Check availability on Hannibal Luxury Hotels

Tonight
Sep 2 - Sep 3
Tomorrow
Sep 3 - Sep 4
This weekend
Sep 4 - Sep 6
Next weekend
Sep 11 - Sep 13

Our top choices for Hannibal luxury hotels

Room
Deluxe Suite | Living area
Superior Suite | Private kitchen
Pool

1. Lighthouse Inn & Suites

Lighthouse Inn & Suites
Hannibal
￥28,678
￥33,080 total
includes taxes & fees
Sep 10 - Sep 11
Lighthouse Inn & Suites
View all properties

Top Hannibal Hotel Reviews

Best Western On The River

Best Western On The River

8/10 Good
"This hotel is very close to all the downtown attractions within walking distance. Very clean. We were looking forward to enjoying time in the hot tub in the evening but it broke down the day we arrived. We were very disappointed to say the least. The beds were very comfortable."
Mary 2-night trip
Posted 6 hours ago
Best Western On The River

Frequently asked questions

Are you searching for the perfect hotel for your luxury trip to Hannibal?
Use Expedia to arrange your flight to Quincy, IL (UIN-Quincy Regional-Baldwin Field) airport, and then choose from a variety of places to stay that will deliver the luxury you seek. Amenities are important when you plan a trip, so we make it easy to find what you'd like to make your stay relaxing and comfortable. If you want an upscale hotel with a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Hannibal has to offer. During your visit, you might want to enjoy the museums which Hannibal is known for.
When can I expect good weather in Hannibal?
Planning for the weather is a good way to make your trip to Hannibal relaxing and enjoyable, especially when you're splurging. The hottest months are usually July and August with an average temp of 74°F, while the coldest months are January and February with an average of 34°F. Average annual precipitation for Hannibal is 47 inches.
What's there to see and do in Hannibal?
Take in some sights and attractions while you're in Hannibal by visiting Rockcliffe Mansion, Mark Twain Boyhood Home and Museum, and Mark Twain Memorial Lighthouse. If you have extra time while you're in the area, you might want to stop by Mark Twain Cave and Mississippi River.

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