A historic downtown street with vintage buildings, a church steeple, and a prominent clock tower.

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Check prices for these dates

Next weekend
Oct 30 - Nov 1
In two weeks
Nov 6 - Nov 8
In one month
Nov 20 - Nov 22
In two months
Dec 18 - Dec 20

Our top choices for Great River Road guest houses

A multi-story building with a grand entrance, large windows, and a well-lit facade at night.

1. Grand Center Inn

Grand Center Inn
3.0 star property
Grand Center
9.4 out of 10, Exceptional, (105 reviews)
"Lovely room, easy check in, close to Fox, comfy bed"
United States
Leon and Janis
The price is ￥24,688
￥29,115 total
includes taxes & fees
Oct 29 - Oct 30
Grand Center Inn
A modern living room with a brick wall, a sofa, a coffee table, and a TV.

2. Cozy, Fun, and One-Of-A-Kind!

Cozy, Fun, and One-Of-A-Kind!
Shaw
9.2 out of 10, Wonderful, (149 reviews)
"Great place to stay super cozy"
United States
Riley C.
The price is ￥9,733
￥21,373 total
includes taxes & fees
Oct 25 - Oct 26
Cozy, Fun, and One-Of-A-Kind!
A park with picnic tables and chairs, a large tree, and a lake in the background.

3. Little Bluff Inn

Little Bluff Inn
2.5 star property
Downtown Trempealeau
10.0 out of 10, Exceptional, (173 reviews)
"Wonderful family run boutique hotel."
United States
DAVID
The price is ￥14,607
￥16,624 total
includes taxes & fees
Oct 28 - Oct 29
Little Bluff Inn
An outdoor patio with a fire feature, wooden deck, and a view of trees.

4. Trailside Inn

Trailside Inn
2.0 star property
Lanark
8.2 out of 10, Very good, (38 reviews)
"Room wad clean and comfortable, as were the beds, quiet area. Overall enjoyed my stay and I'll use them again if I'm in the area."
United States
Jon
The price is ￥15,516
￥17,220 total
includes taxes & fees
Nov 2 - Nov 3
Trailside Inn
A spacious room with a high ceiling, wooden beams, and a large window displaying a sign for The Rushford Inn.

5. The Rushford Inn

The Rushford Inn
3.0 star property
Rushford
9.4 out of 10, Exceptional, (9 reviews)
"Perfect location to have a reunion."
United States
sonja
The price is ￥22,428
￥24,083 total
includes taxes & fees
Oct 28 - Oct 29
The Rushford Inn
A room with a beige leather sofa, a wooden coffee table, a floor lamp, and a patterned carpet.

6. Riverside Inn Hannibal

Riverside Inn Hannibal
2.5 star property
Hannibal
9.6 out of 10, Exceptional, (203 reviews)
"Very nice room and great view of the river. Very comfortable bed and very nice shower. Walking distance to so many restaurants and shops. We enjoyed our stay very much!"
United States
Christina
The price is ￥23,544
￥32,583 total
includes taxes & fees
Oct 26 - Oct 27
Riverside Inn Hannibal
A two-story house with a porch, surrounded by well-maintained lawns and trees.

7. Aurora Staples Inn

Aurora Staples Inn
3.0 star property
Stillwater
9.6 out of 10, Exceptional, (266 reviews)
"Lovely home in a great location. Would definitely stay here again."
United States
Amy
The price is ￥30,629
￥34,268 total
includes taxes & fees
Nov 1 - Nov 2
Aurora Staples Inn
A hotel room with two beds, a nightstand, and two wall-mounted lamps.

8. The Sawmill Inn

The Sawmill Inn
3.0 star property
Houston
9.0 out of 10, Wonderful, (14 reviews)
"Nice size kitchen living room and bedroom."
United States
Josie
The price is ￥22,428
￥23,970 total
includes taxes & fees
Nov 2 - Nov 3
The Sawmill Inn
A cozy kitchen with wooden beams, a central island, bar stools, and a dining table.

9. Cozy A-Frame house in heart of the midwest!!!

Cozy A-Frame house in heart of the midwest!!!
Quincy
9.8 out of 10, Exceptional, (183 reviews)
"We had an awesome stay! The place was super clean and had everything we could need at the property! "
United States
Melanie B.
The price is ￥20,375
￥33,719 total
includes taxes & fees
Oct 25 - Oct 26
Cozy A-Frame house in heart of the midwest!!!
A white house with green shutters, a front porch, and a small garden.

10. Steele Cottage

Steele Cottage
3.0 star property
Vicksburg
9.0 out of 10, Wonderful, (198 reviews)
"Large clean first floor easy access for us Seniors. Big Bathroom. Great custom Breakfast at Duff nearby. Plan to return next October."
United States
Richard
The price is ￥14,239
￥15,664 total
includes taxes & fees
Nov 1 - Nov 2
Steele Cottage
A living room with a sofa, armchair, small table, and a rug.

11. Canton River House, Steps from Culver-Stockton

Canton River House, Steps from Culver-Stockton
Canton
10.0 out of 10, Exceptional, (2 reviews)
"Perfect little cozy house. I enjoyed spending time with my son who is 8 hours away in college. House was perfect, temperature was great, clean, bedding towels everything you need! Highly recommend you stay here!"
United States
Whitney S.
The price is ￥14,145
￥28,704 total
includes taxes & fees
Nov 3 - Nov 4
Canton River House, Steps from Culver-Stockton
A bedroom with a wooden headboard, a quilted bedspread, and a nightstand.

12. Honnoll's High Cotton Guesthouse

Honnoll's High Cotton Guesthouse
Cleveland
9.8 out of 10, Exceptional, (72 reviews)
"We had a lovely stay, and our host was very nice and communicative. We definitely recommend this stay!"
United States
Ashley K.
The price is ￥19,435
￥31,495 total
includes taxes & fees
Oct 26 - Oct 27
Honnoll's High Cotton Guesthouse
A modern bar area with a long counter, multiple stools, and a variety of glassware and bottles on shelves.

13. The Inn at Cedar Grove

The Inn at Cedar Grove
3.5 star property
Vicksburg
9.0 out of 10, Wonderful, (199 reviews)
"Friendly staff"
United States
kent
The price is ￥22,022
￥24,224 total
includes taxes & fees
Nov 8 - Nov 9
The Inn at Cedar Grove
A historic building with a sign reading "American House 1854."

14. American House 1854- Stagecoach Stop Suite, 2 Bedrooms, Kitchenette, Sleeps 6

American House 1854- Stagecoach Stop Suite, 2 Bedrooms, Kitchenette, Sleeps 6
McGregor
10.0 out of 10, Exceptional, (30 reviews)
"Great host great location "
United States
Pamela H.
The price is ￥22,428
￥48,467 total
includes taxes & fees
Oct 26 - Oct 27
American House 1854- Stagecoach Stop Suite, 2 Bedrooms, Kitchenette, Sleeps 6
A two-story building with a covered porch, a brick wall on the left, and a white fence with greenery.

15. The Carriage House on St. Charles

The Carriage House on St. Charles
3.5 star property
Central City
8.8 out of 10, Excellent, (400 reviews)
"Wonderful property in the heart of New Orleans! The staff were exceptional! Very responsive and helpful. Very comfortable beds, nice clean room, great location!"
United States
Jessica
The price is ￥14,134
￥22,253 total
includes taxes & fees
Nov 3 - Nov 4
The Carriage House on St. Charles
A brown leather armchair with a cushion that has text, positioned in front of a window with white curtains.

16. The Natchez Pearl

The Natchez Pearl
3.0 star property
Natchez
9.6 out of 10, Exceptional, (213 reviews)
"Walking distance to many historic attractions. Excellent room."
United States
Duane
The price is ￥19,583
￥38,234 total
includes taxes & fees
Oct 29 - Oct 30
The Natchez Pearl
A living room with two grey sofas, a patterned rug, and a chandelier.

17. WG Creole House 1850

WG Creole House 1850
3.0 star property
Central City
9.2 out of 10, Wonderful, (559 reviews)
"Had a new Orleans charm that you can't get from hotel. Great location and the aints stadiums and a bus straight to the airport is less than 12 minutes away walking distance!"
United States
Irving
The price is ￥10,165
￥11,259 total
includes taxes & fees
Nov 23 - Nov 24
WG Creole House 1850
A row of three-story buildings with balconies, a central building with a porch, and a green railing in the foreground.

18. The Mansion on Royal

The Mansion on Royal
3.0 star property
Faubourg Marigny
7.2 out of 10, Good, (46 reviews)
"Perfect room for a short quick getaway. "
United States
Brian
The price is ￥11,633
￥27,767 total
includes taxes & fees
Oct 26 - Oct 27
The Mansion on Royal
A building with a porch, outdoor seating, and a flag.

19. Gorgeous loft in the heart of LeClaire, Iowa

Gorgeous loft in the heart of LeClaire, Iowa
Le Claire
10.0 out of 10, Exceptional, (112 reviews)
"Beautiful view of Downtown LeClaire and walking distance to everything that you would like to do. Beautiful property!"
United States
Aaron
The price is ￥27,428
￥45,640 total
includes taxes & fees
Oct 25 - Oct 26
Gorgeous loft in the heart of LeClaire, Iowa
A rustic log cabin with a porch, wooden furniture, and a large tree in the foreground.

20. Pecan Grove Cottages

Pecan Grove Cottages
3.0 star property
Martin
10.0 out of 10, Exceptional, (82 reviews)
"What a great place to stay! "
United States
Amy
The price is ￥28,368
￥33,687 total
includes taxes & fees
Oct 29 - Oct 30
Pecan Grove Cottages
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Great River Road Hotel Reviews

AmericInn by Wyndham Prairie du Chien

AmericInn by Wyndham Prairie du Chien

10/10 Excellent
"We enjoyed our stay!"
Angie 2-night trip
Posted 4 days ago
AmericInn by Wyndham Prairie du Chien

Find out more about Great River Road

Great River Road Guest Houses information

Number of reviews
2,190
Accommodation
0 Guest Houses
Lowest Price
￥11,259
Highest Price
￥48,467