A beach with palm trees, people relaxing on chairs, and colorful kayaks.

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Check availability on Florida Keys Luxury Hotels

Tonight
Sep 6 - Sep 7
Tomorrow
Sep 7 - Sep 8
Next weekend
Sep 11 - Sep 13
In two weeks
Sep 18 - Sep 20

Our top choices for Florida Keys luxury hotels

1. The Islands of Islamorada

The Islands of Islamorada
Matecumbe
¥61,386
¥78,902 total
includes taxes & fees
Sep 15 - Sep 16
The Islands of Islamorada

2. Villas At Hawks Cay Resort

Villas At Hawks Cay Resort
Marathon
  • Indulge in oceanfront splendor at this Florida Keys resort with 5 pools, private beach, and full-service spa treatments.
¥59,223
¥76,296 total
includes taxes & fees
Sep 13 - Sep 14
Villas At Hawks Cay Resort

3. Ocean Key Resort - A Noble House Resort

Ocean Key Resort - A Noble House Resort
Key West Historic District
¥34,401
¥50,832 total
includes taxes & fees
Sep 28 - Sep 29
Ocean Key Resort - A Noble House Resort

4. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
  • Beachfront luxury awaits at this Key Largo resort with spa treatments and ocean views.
¥39,846
¥53,442 total
includes taxes & fees
Sep 20 - Sep 21
Playa Largo Resort & Spa, Autograph Collection

5. Opal Key Resort & Marina, Key West

Opal Key Resort & Marina, Key West
Old Town Key West
¥40,471
¥51,685 total
includes taxes & fees
Sep 7 - Sep 8
Opal Key Resort & Marina, Key West

6. Pier House Resort & Spa

Pier House Resort & Spa
Key West Historic District
¥40,774
¥56,770 total
includes taxes & fees
Sep 13 - Sep 14
Pier House Resort & Spa

7. Santa Maria Suites

Santa Maria Suites
Old Town Key West
  • Lavish Key West retreat features luxury suites, designer touches, 2 pools, and vibrant bar scene.
¥43,597
¥59,594 total
includes taxes & fees
Sep 7 - Sep 8
Santa Maria Suites

8. Hyatt Centric Key West Resort and Spa

Hyatt Centric Key West Resort and Spa
Key West Historic District
¥31,096
¥45,882 total
includes taxes & fees
Sep 28 - Sep 29
Hyatt Centric Key West Resort and Spa

9. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
¥34,221
¥44,749 total
includes taxes & fees
Sep 7 - Sep 8
Reefhouse Resort & Marina

10. Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
Key Largo
  • Beach luxury reimagined at Key Largo resort with private sands, refreshing pools, and coastal dining.
¥37,030
¥50,274 total
includes taxes & fees
Sep 28 - Sep 29
Baker's Cay Resort Key Largo, Curio Collection by Hilton
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Find out more about Florida Keys

Florida Keysand its attractions for luxury travelers

In the Florida Keys, luxury travelers can indulge in a variety of high-end experiences that blend relaxation with adventure. Begin your journey in Key West, where you can visit the historic Ernest Hemingway Home and Museum, offering a glimpse into the life of the iconic author while surrounded by lush gardens. For a unique aquatic experience, charter a private yacht to explore the stunning coral reefs of the Florida Keys National Marine Sanctuary, where snorkeling and diving unveil vibrant underwater ecosystems. Gourmet dining awaits at the renowned Latitudes, perched on Sunset Key, where you can savor fresh seafood while watching the sun dip below the horizon. For those seeking relaxation, indulge in a spa day at a luxury resort like the Ocean Key Resort & Spa, where you can enjoy rejuvenating treatments with ocean views. Staying in the upscale area of Islamorada allows travelers to enjoy a slower pace with beachfront resorts like the Moorings Village, providing an intimate setting with lush tropical gardens and private beach access, perfect for families seeking both adventure and pampering. With attentive service and exquisite surroundings, the Florida Keys present a captivating escape for travelers.

Top Florida Keys Hotel Reviews

Waterside Suites & Marina

Waterside Suites & Marina

8/10 Good
"Great suite. Very comfortable and inviting"
Laurence 1-night trip
Posted 10 hours ago
Waterside Suites & Marina
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton

10/10 Excellent
"AMAZING STAY! Book here for a couple, family or solo trip. Amazing amenities , private beach, pool and restaurants on site. The grounds are gorgeous and clean. Staff super friendly and rooms are great. Nicky at front desk was a great help Look no further for beautiful sunsets and sunrises"
Irene 1-night trip
Posted 12 hours ago
Baker's Cay Resort Key Largo, Curio Collection by Hilton
Chesapeake Beach Resort

Chesapeake Beach Resort

10/10 Excellent
"On arrival, was met by friendly staff, who made us very very welcome! Room was fantastic and very clean! Breakfast was amazing... overall had a great stay, in future will stay longer."
Daniel 1-night trip
Posted 13 hours ago
Chesapeake Beach Resort
The Pelican Key Largo Cottages

The Pelican Key Largo Cottages

10/10 Excellent
"-"
Julie 1-night trip
Posted 17 hours ago
The Pelican Key Largo Cottages
Reefhouse Resort & Marina

Reefhouse Resort & Marina

8/10 Good
"We enjoyed our stay here, were upgraded to a partial view room, and noticed to have been among the only people in the pool or dining area when we took did these activities. The staff was attentive, but seemed bothered by the lack of business that they were having, and we felt like a bit of an afterthought at times despite enjoying the resort being “to ourselves”."
Brian 1-night trip
Posted 1 day ago
Reefhouse Resort & Marina
Fairfield Inn & Suites by Marriott Marathon Florida Keys

Fairfield Inn & Suites by Marriott Marathon Florida Keys

8/10 Good
"Pool area was really nice, breakfast was ok but not much variety. Room was good, had everything you needed"
Lucy 1-night trip
Posted 3 days ago
Fairfield Inn & Suites by Marriott Marathon Florida Keys

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