A beach with palm trees, people relaxing on chairs, and colorful kayaks.

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Check availability on Florida Keys Luxury Hotels

Tonight
Sep 24 - Sep 25
Tomorrow
Sep 25 - Sep 26
This weekend
Sep 25 - Sep 27
Next weekend
Oct 2 - Oct 4

Our top choices for Florida Keys luxury hotels

1. The Islands of Islamorada

The Islands of Islamorada
Matecumbe
¥64,100
¥82,119 total
includes taxes & fees
Oct 1 - Oct 2
The Islands of Islamorada

2. Villas At Hawks Cay Resort

Villas At Hawks Cay Resort
Marathon
  • Indulge in oceanfront splendor at this Florida Keys resort with 5 pools, private beach, and full-service spa treatments.
¥59,674
¥76,877 total
includes taxes & fees
Sep 27 - Sep 28
Villas At Hawks Cay Resort

3. Santa Maria Suites

Santa Maria Suites
Old Town Key West
  • Lavish Key West retreat features luxury suites, designer touches, 2 pools, and vibrant bar scene.
¥43,929
¥60,047 total
includes taxes & fees
Sep 27 - Sep 28
Santa Maria Suites

4. Opal Key Resort & Marina, Key West

Opal Key Resort & Marina, Key West
Old Town Key West
¥40,780
¥52,078 total
includes taxes & fees
Sep 28 - Sep 29
Opal Key Resort & Marina, Key West

5. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
  • Beachfront luxury awaits at this Key Largo resort with spa treatments and ocean views.
¥41,625
¥55,553 total
includes taxes & fees
Oct 8 - Oct 9
Playa Largo Resort & Spa, Autograph Collection

6. Hyatt Centric Key West Resort and Spa

Hyatt Centric Key West Resort and Spa
Key West Historic District
¥32,920
¥48,074 total
includes taxes & fees
Sep 28 - Sep 29
Hyatt Centric Key West Resort and Spa

7. Ocean Key Resort - A Noble House Resort

Ocean Key Resort - A Noble House Resort
Key West Historic District
¥30,585
¥46,631 total
includes taxes & fees
Sep 30 - Oct 1
Ocean Key Resort - A Noble House Resort

8. Pier House Resort & Spa

Pier House Resort & Spa
Key West Historic District
¥34,810
¥50,143 total
includes taxes & fees
Sep 30 - Oct 1
Pier House Resort & Spa

9. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
¥31,333
¥41,548 total
includes taxes & fees
Sep 28 - Sep 29
Reefhouse Resort & Marina

10. Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
Key Largo
  • Beach luxury reimagined at Key Largo resort with private sands, refreshing pools, and coastal dining.
¥42,081
¥56,065 total
includes taxes & fees
Oct 1 - Oct 2
Baker's Cay Resort Key Largo, Curio Collection by Hilton
View all properties

Find out more about Florida Keys

Florida Keysand its attractions for luxury travelers

In the Florida Keys, luxury travelers can indulge in a variety of high-end experiences that blend relaxation with adventure. Begin your journey in Key West, where you can visit the historic Ernest Hemingway Home and Museum, offering a glimpse into the life of the iconic author while surrounded by lush gardens. For a unique aquatic experience, charter a private yacht to explore the stunning coral reefs of the Florida Keys National Marine Sanctuary, where snorkeling and diving unveil vibrant underwater ecosystems. Gourmet dining awaits at the renowned Latitudes, perched on Sunset Key, where you can savor fresh seafood while watching the sun dip below the horizon. For those seeking relaxation, indulge in a spa day at a luxury resort like the Ocean Key Resort & Spa, where you can enjoy rejuvenating treatments with ocean views. Staying in the upscale area of Islamorada allows travelers to enjoy a slower pace with beachfront resorts like the Moorings Village, providing an intimate setting with lush tropical gardens and private beach access, perfect for families seeking both adventure and pampering. With attentive service and exquisite surroundings, the Florida Keys present a captivating escape for travelers.

Top Florida Keys Hotel Reviews

The Pelican Key Largo Cottages

The Pelican Key Largo Cottages

10/10 Excellent
"The place had character and culture that modern sterile resorts do not."
Wayne 1-night trip
Posted 5 hours ago
The Pelican Key Largo Cottages
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

8/10 Good
"Room was OK with killer water view!"
Rick 3-night trip
Posted 8 hours ago
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
Bayside Inn Key Largo

Bayside Inn Key Largo

10/10 Excellent
"The staff was great very friendly. The place is located really nice beautiful sunset. Had a great time."
Marco 1-night trip
Posted 8 hours ago
Bayside Inn Key Largo
Chesapeake Beach Resort

Chesapeake Beach Resort

10/10 Excellent
"This facility was clean and well managed. The 2 pools were perfect. The beach area was well maintained. We utilized the free kayaks two days in a row. The breakfast was delicious and had made to order pancakes and omelets. The staff was very friendly. I highly recommend this resort."
Holly 4-night trip
Posted 9 hours ago
Chesapeake Beach Resort
Amara Cay Resort

Amara Cay Resort

10/10 Excellent
"."
OLGA 1-night trip
Posted 9 hours ago
Amara Cay Resort
Hampton Inn Key Largo Manatee Bay

Hampton Inn Key Largo Manatee Bay

10/10 Excellent
"Nice hotel, continuing to update. Enjoyed the outdoor bar and sunset view. Beautiful location for sunset"
ANNA 1-night trip
Posted 2 days ago
Hampton Inn Key Largo Manatee Bay
Sunset Cove Beach Resort

Sunset Cove Beach Resort

8/10 Good
"Takes pets for reasonable rate; but no pool"
Deborah 2-night trip
Posted 2 days ago
Sunset Cove Beach Resort
Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection

10/10 Excellent
"Todo perfecto solo q en los Restaurantes no hay desayuno incluido, y los Plato’s están por en ima de la media de sus precios y en realidad no vale la pens pagarlos en ima de eso se demoran mucho"
Raul 2-night trip
Posted 2 days ago
Playa Largo Resort & Spa, Autograph Collection
Fairfield Inn & Suites by Marriott Marathon Florida Keys

Fairfield Inn & Suites by Marriott Marathon Florida Keys

10/10 Excellent
"We had a good time"
melinda 5-night trip
Posted 2 days ago
Fairfield Inn & Suites by Marriott Marathon Florida Keys

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