A beach with palm trees, people relaxing on chairs, and colorful kayaks.

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Check availability on Florida Keys Luxury Hotels

Tonight
Sep 17 - Sep 18
Tomorrow
Sep 18 - Sep 19
This weekend
Sep 18 - Sep 20
Next weekend
Sep 25 - Sep 27

Our top choices for Florida Keys luxury hotels

1. The Islands of Islamorada

The Islands of Islamorada
Matecumbe
¥62,828
¥80,490 total
includes taxes & fees
Sep 21 - Sep 22
The Islands of Islamorada

2. Villas At Hawks Cay Resort

Villas At Hawks Cay Resort
Marathon
  • Indulge in oceanfront splendor at this Florida Keys resort with 5 pools, private beach, and full-service spa treatments.
¥58,794
¥75,743 total
includes taxes & fees
Sep 20 - Sep 21
Villas At Hawks Cay Resort

3. Opal Key Resort & Marina, Key West

Opal Key Resort & Marina, Key West
Old Town Key West
¥40,179
¥51,311 total
includes taxes & fees
Sep 21 - Sep 22
Opal Key Resort & Marina, Key West

4. Santa Maria Suites

Santa Maria Suites
Old Town Key West
  • Lavish Key West retreat features luxury suites, designer touches, 2 pools, and vibrant bar scene.
¥43,602
¥59,601 total
includes taxes & fees
Sep 21 - Sep 22
Santa Maria Suites

5. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
  • Beachfront luxury awaits at this Key Largo resort with spa treatments and ocean views.
¥39,851
¥53,448 total
includes taxes & fees
Oct 1 - Oct 2
Playa Largo Resort & Spa, Autograph Collection

6. Ocean Key Resort - A Noble House Resort

Ocean Key Resort - A Noble House Resort
Key West Historic District
¥34,405
¥50,838 total
includes taxes & fees
Sep 30 - Oct 1
Ocean Key Resort - A Noble House Resort

7. Hyatt Centric Key West Resort and Spa

Hyatt Centric Key West Resort and Spa
Key West Historic District
¥35,990
¥51,309 total
includes taxes & fees
Oct 5 - Oct 6
Hyatt Centric Key West Resort and Spa

8. Casa Marina Key West, Curio Collection by Hilton

Casa Marina Key West, Curio Collection by Hilton
Old Town Key West
  • Beachfront luxury graces historic Key West resort with private shore access and spa treatments.
¥34,405
¥49,255 total
includes taxes & fees
Sep 27 - Sep 28
Casa Marina Key West, Curio Collection by Hilton

9. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
¥33,973
¥44,425 total
includes taxes & fees
Sep 20 - Sep 21
Reefhouse Resort & Marina

10. Pier House Resort & Spa

Pier House Resort & Spa
Key West Historic District
¥30,867
¥45,546 total
includes taxes & fees
Sep 30 - Oct 1
Pier House Resort & Spa
View all properties

Find out more about Florida Keys

Florida Keysand its attractions for luxury travelers

In the Florida Keys, luxury travelers can indulge in a variety of high-end experiences that blend relaxation with adventure. Begin your journey in Key West, where you can visit the historic Ernest Hemingway Home and Museum, offering a glimpse into the life of the iconic author while surrounded by lush gardens. For a unique aquatic experience, charter a private yacht to explore the stunning coral reefs of the Florida Keys National Marine Sanctuary, where snorkeling and diving unveil vibrant underwater ecosystems. Gourmet dining awaits at the renowned Latitudes, perched on Sunset Key, where you can savor fresh seafood while watching the sun dip below the horizon. For those seeking relaxation, indulge in a spa day at a luxury resort like the Ocean Key Resort & Spa, where you can enjoy rejuvenating treatments with ocean views. Staying in the upscale area of Islamorada allows travelers to enjoy a slower pace with beachfront resorts like the Moorings Village, providing an intimate setting with lush tropical gardens and private beach access, perfect for families seeking both adventure and pampering. With attentive service and exquisite surroundings, the Florida Keys present a captivating escape for travelers.

Top Florida Keys Hotel Reviews

Amara Cay Resort

Amara Cay Resort

10/10 Excellent
"amazing clean stay."
MICHAEL 2-night trip
Posted 1 hour ago
Amara Cay Resort
Sunset Cove Beach Resort

Sunset Cove Beach Resort

10/10 Excellent
"The staff was super friendly and helpful. The room was spotless. Comfy bed and clean room. The beach area and the property are amazing. Lighting at night is incredible. The whole place comes alive. Breakfast u see the tiki has coffee, oj and treats. Will definitely be back"
Jesus 2-night trip
Posted 2 hours ago
Sunset Cove Beach Resort
The Pelican Key Largo Cottages

The Pelican Key Largo Cottages

10/10 Excellent
"This is so peaceful. We have been 5x now and if you are looking for quaint and peaceful this is it. Very clean very nice people. Literally the only drawback is we cannot bring our jetskis, but get it."
kimberly 1-night trip
Posted 2 hours ago
The Pelican Key Largo Cottages
Chesapeake Beach Resort

Chesapeake Beach Resort

8/10 Good
"It was great."
Clay 1-night trip
Posted 3 hours ago
Chesapeake Beach Resort
Waterside Suites & Marina

Waterside Suites & Marina

8/10 Good
"The water in the outdoor pool was so hot and limited seats. Probably need a cooling system. Loved the location and watching the boats. The townhome was excellent minus the coffee filters. Also, would not recommend for people with disabilities. There were no elevators going up to the townhome on 2nd floor and also the room in the townhome was on the second floor. The front desk person was super nice. Would stay here again if we were staying long term."
Sandra 3-night trip
Posted 4 hours ago
Waterside Suites & Marina
Hawks Cay Resort

Hawks Cay Resort

8/10 Good
"The place are beautiful!!! The staff were very nice and welcoming!!! We booked the 3 bedroom premium villa which is upgraded and little bigger it was really cool we love it , the only thing was that we had an issue with the Wifi we complained the moment we found out they said we send someone no one come!!! We keeping asking and asking we went to the front desk we will send the IT guy in hour we were there for 5 days he never come!!!!! The Arcade room and fitness room Was open 8-5 nothing to do after 5pm very disappointed, the water park was closed the Dolphin was closed no Dolphin!!! Restaurant is little over priced!!!! The place is very beautiful !!!"
EYAL 4-night trip
Posted 12 hours ago
Hawks Cay Resort
Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection

10/10 Excellent
"we enjoyed our stay, everything deserved 5 stars"
Tanya 4-night trip
Posted 1 day ago
Playa Largo Resort & Spa, Autograph Collection
Hampton Inn Key Largo Manatee Bay

Hampton Inn Key Largo Manatee Bay

10/10 Excellent
"Easy check in, clean room, great breakfast, delightful beach and outdoor pool. We will return in the Fall since we loved our stay."
Carla 3-night trip
Posted 1 day ago
Hampton Inn Key Largo Manatee Bay
Lime Tree Bay Resort

Lime Tree Bay Resort

10/10 Excellent
"100% recommended"
Jairo 1-night trip
Posted 1 day ago
Lime Tree Bay Resort

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