Find Resorts & Hotels with Spas in Florence, SC

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Florence Resorts & Hotels with Spas

Tonight
Dec 30 - Dec 31
Tomorrow
Dec 31 - Jan 1
This weekend
Jan 2 - Jan 4
Next weekend
Jan 9 - Jan 11

Our top choices for Florence hotels with a spa

Sports facility
Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton
3.0 star property
Florence
8.8 out of 10, Excellent, (607)
"Special place. Great staff with an outstanding restaurant "
United States
John D
The price is ￥20,335
￥22,774 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Hotel Florence, Tapestry Collection by Hilton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Florence Hotel Reviews

Residence Inn Marriott Florence

Residence Inn Marriott Florence

10/10 Excellent
"Staff was very friendly The room Is spacious and very clean . There is plenty of green space outside for our dog !"
Harriet 1-night trip
Posted 4 days ago
Residence Inn Marriott Florence
Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton

10/10 Excellent
"Very nice facility; lots of character. Convenient parking. Good breakfast. Very pleasant staff. Would definitely return. "
Holt 1-night trip
Posted 7 days ago
Hotel Florence, Tapestry Collection by Hilton

Frequently asked questions

Looking to vacation at a spa hotel in Florence?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Travelers highly recommend the restaurants in Florence. Be sure to pay a visit to the museums during your stay. Spa hotels are a great way to break out of your routine and add a layer of luxury to your holiday.
What is the best spa hotel in Florence?
Hotel Florence, Tapestry Collection by Hilton is a top spa hotel featuring a 24-hour fitness center, a bar, and a restaurant. Enjoy a facial, detox wrap, or Swedish massage at the onsite spa.
How many spa hotels are there in Florence?
Among Expedia's 109 accommodation options in Florence, there is 1 spa hotel.
What's there to see and do in Florence?
Enjoy all that Florence has to offer when you visit Florence Museum, Florence National Cemetery, and Dr. Eddie Floyd Tennis Center. If you have extra time while you're in the area, you might want to see Magnolia Mall and Florence Veterans Park.
What is a Florence spa hotel?
Spa hotels in Florence provide lodging and have an on-site spa which offers services like couples massages as well as body treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.