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Discover 772 East Seneca hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

M Hotel Buffalo
Reception hall

M Hotel Buffalo

3.5 star property
7.2 out of 10, Good, (2197)
"Very nice Hotel at a reasonable price. "
M Hotel Buffalo
Sleep Inn & Suites Buffalo Airport
Lobby

Sleep Inn & Suites Buffalo Airport

2.5 star property
8.0 out of 10, Very Good, (1764)
"The hotel is nice & close to the airport."
The price is ￥10,407
￥11,837 total
includes taxes & fees
Oct 26 - Oct 27
Sleep Inn & Suites Buffalo Airport
Quality Inn Near Walden Galleria Mall
Free daily continental breakfast

Quality Inn Near Walden Galleria Mall

2.5 star property
8.0 out of 10, Very Good, (1045)
"Staff is great and place is clean"
The price is ￥15,374
￥17,487 total
includes taxes & fees
Oct 1 - Oct 2
Quality Inn Near Walden Galleria Mall
Best Western Galleria Inn & Suites
Desk, blackout drapes, iron/ironing board, free cribs/infant beds

Best Western Galleria Inn & Suites

2.5 star property
6.6 out of 10, (1017)
"Great stay"
The price is ￥16,442
￥18,703 total
includes taxes & fees
Sep 30 - Oct 1
Best Western Galleria Inn & Suites
Days Inn by Wyndham Tonawanda/Buffalo
Standard Room, 2 Queen Beds, Non Smoking | Premium bedding, desk, laptop workspace, blackout drapes

Days Inn by Wyndham Tonawanda/Buffalo

2.0 star property
6.0 out of 10, (853)
"Great spot for a weekend shopping trip "
The price is ￥11,690
￥13,297 total
includes taxes & fees
Oct 13 - Oct 14
Days Inn by Wyndham Tonawanda/Buffalo
Buffalo Airport Hotel
Courtyard view

Buffalo Airport Hotel

3.0 star property
8.0 out of 10, Very Good, (2695)
"Nice place to stay"
The price is ￥16,537
￥18,811 total
includes taxes & fees
Sep 30 - Oct 1
Buffalo Airport Hotel
Holiday Inn Express & Suites Tonawanda - Buffalo Area by IHG
Free daily self-serve breakfast

Holiday Inn Express & Suites Tonawanda - Buffalo Area by IHG

2.5 star property
8.8 out of 10, Excellent, (609)
"We enjoyed staying there"
The price is ￥20,032
￥22,786 total
includes taxes & fees
Oct 7 - Oct 8
Holiday Inn Express & Suites Tonawanda - Buffalo Area by IHG
Garden Place Hotel
Reception

Garden Place Hotel

3.5 star property
7.8 out of 10, Good, (1934)
"Super nice staff, beautiful hotel, quiet…perfect place to stay!"
Garden Place Hotel
Hyatt Place Buffalo/Amherst
Exterior

Hyatt Place Buffalo/Amherst

3.0 star property
9.0 out of 10, Wonderful, (1083)
"Clean, comfortable and great staff!"
The price is ￥24,068
￥27,378 total
includes taxes & fees
Oct 13 - Oct 14
Hyatt Place Buffalo/Amherst
La Quinta Inn by Wyndham Buffalo Airport
Exterior

La Quinta Inn by Wyndham Buffalo Airport

3.0 star property
7.8 out of 10, Good, (1262)
"Good place to stay for an overnight "
The price is ￥13,976
￥15,898 total
includes taxes & fees
Oct 7 - Oct 8
La Quinta Inn by Wyndham Buffalo Airport
Sleep Inn
Indoor pool

Sleep Inn

2.5 star property
8.8 out of 10, Excellent, (1125)
"Location was great!"
The price is ￥14,486
￥16,477 total
includes taxes & fees
Oct 13 - Oct 14
Sleep Inn
Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG
Property entrance

Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG

2.5 star property
8.2 out of 10, Very Good, (1018)
"Second time staying in the hotel. It's everything you need."
The price is ￥17,640
￥20,066 total
includes taxes & fees
Oct 21 - Oct 22
Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG
Homewood Suites by Hilton Buffalo Airport
Fireplace

Homewood Suites by Hilton Buffalo Airport

3.0 star property
8.4 out of 10, Very Good, (1010)
"Friendly staff, clean rooms, tasty breakfast."
The price is ￥24,149
￥27,469 total
includes taxes & fees
Oct 19 - Oct 20
Homewood Suites by Hilton Buffalo Airport
Candlewood Suites Buffalo - Amherst by IHG
Terrace/patio

Candlewood Suites Buffalo - Amherst by IHG

2.5 star property
8.6 out of 10, Excellent, (924)
"My stay was very pleasant and comfortable"
The price is ￥15,995
￥18,195 total
includes taxes & fees
Oct 1 - Oct 2
Candlewood Suites Buffalo - Amherst by IHG
Hyatt Regency Buffalo / Hotel and Conference Center
Indoor pool

Hyatt Regency Buffalo / Hotel and Conference Center

3.5 star property
8.0 out of 10, Very Good, (1581)
"Rooms were clean, hotel accessible, staff AMAZING!!! "
The price is ￥19,326
￥22,563 total
includes taxes & fees
Oct 19 - Oct 20
Hyatt Regency Buffalo / Hotel and Conference Center
Hampton Inn Buffalo - Amherst, NY
Exterior

Hampton Inn Buffalo - Amherst, NY

2.5 star property
9.4 out of 10, Exceptional, (1874)
"Great stay, very convenient "
The price is ￥16,093
￥18,307 total
includes taxes & fees
Oct 7 - Oct 8
Hampton Inn Buffalo - Amherst, NY
Fairbridge Inn Express Buffalo Airport Williamsville
Exterior

Fairbridge Inn Express Buffalo Airport Williamsville

2.0 star property
4.6 out of 10, (1024)
"Basic room but for the price paid overall very happy. "
The price is ￥9,014
￥10,254 total
includes taxes & fees
Oct 13 - Oct 14
Fairbridge Inn Express Buffalo Airport Williamsville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in East Seneca

Find the best East Seneca areas and neighborhoods for the activities you enjoy most.
Buffalo showing a city, a monument and a skyscraper

Downtown Buffalo

Experience the city's rich culture with visits to the oldest urban parks system in the US, Albright–Knox Art Gallery, and Shea's Performing Arts Center. Enjoy annual festivals and explore nearby universities.

Delaware Park showing a lake or waterhole

North Buffalo

The live music and zoo are just a few things visitors like about North Buffalo. Buffalo Zoo and Buffalo AKG Art Museum are worthwhile spots to check out, and you can hop on the metro at Amherst Street Station or Lasalle Station to get around the larger area.

Elmwood Village

Travelers come to Elmwood Village for its live music, and you can see top attractions like Blue Sky Mausoleum and Ujima Theatre Company while you're in town.

Allentown

Embracing bohemian and hipster culture, this artistic community offers vibrant nightlife, diverse dining, and antique shopping. Explore the Allentown Historic District, including the renowned Kleinhans Music Hall.

Willert Park

Willert Park might not have many top sights, but Shea's Performing Arts Center and Burt Flickinger Athletic Center are two attractions nearby that you can check out.

Top East Seneca Hotel Reviews

Hyatt Regency Buffalo / Hotel and Conference Center

Hyatt Regency Buffalo / Hotel and Conference Center

10/10 Excellent
"Nothing to add"
Matthew 2-night trip
Posted 3 days ago
Hyatt Regency Buffalo / Hotel and Conference Center

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What is East Seneca like?

Travelers will be sure to enjoy their time in West Seneca's East Seneca neighborhood.

If I need to cancel my hotel reservation in East Seneca, will I receive a refund?

Yes! Most hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If your reservation is non-refundable, you may still be able to cancel and be given a refund within a 24-hour period of booking. Add dates, click "Search", then use the filter option "fully refundable" to view the best deals available in East Seneca.

Where can I learn more about changing or cancelling my trip to East Seneca?

For more information about updating your trip to East Seneca or cancelling it, go to https://www.expedia.com/service/.

What is there to do in this West Seneca neighborhood?

A few places to visit in the area around East Seneca include Southgate Plaza, Harvest Hill Golf Course, and Charles E. Burchfield Nature and Art Center. You might also plan a visit to Enjoy The Journey Art Gallery when you're sightseeing in West Seneca.