Find Luxury Hotels in Central United States
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check availability on Central United States Luxury Hotels
Top Central United States Luxury Hotels
Our top choices for Central United States luxury hotels

The St. Anthony, A Luxury Collection Hotel, San Antonio
The St. Anthony, A Luxury Collection Hotel, San Antonio
8.8 out of 10, Excellent, (1008)
The price is ¥26,483
¥31,305 total
includes taxes & fees
Sep 25 - Sep 26

Hotel Viata
Hotel Viata
9.4 out of 10, Exceptional, (634)
The price is ¥30,922
¥39,050 total
includes taxes & fees
Sep 27 - Sep 28

Trump International Hotel & Tower Chicago
Trump International Hotel & Tower Chicago
9.4 out of 10, Exceptional, (1724)
The price is ¥68,242
¥80,109 total
includes taxes & fees
Oct 5 - Oct 6

The Pfister Hotel
The Pfister Hotel
9.6 out of 10, Exceptional, (1749)
The price is ¥27,354
¥32,250 total
includes taxes & fees
Oct 16 - Oct 17

The Langham, Chicago
The Langham, Chicago
9.8 out of 10, Exceptional, (1005)
The price is ¥89,880
¥105,509 total
includes taxes & fees
Oct 5 - Oct 6

Omni Dallas Hotel
Omni Dallas Hotel
9.0 out of 10, Wonderful, (2985)
The price is ¥36,841
¥43,863 total
includes taxes & fees
Sep 26 - Sep 27

The Peninsula Chicago
The Peninsula Chicago
9.8 out of 10, Exceptional, (1008)
The price is ¥92,469
¥108,549 total
includes taxes & fees
Sep 21 - Sep 22

The Gwen, a Luxury Collection Hotel, Michigan Avenue Chicago
The Gwen, a Luxury Collection Hotel, Michigan Avenue Chicago
9.4 out of 10, Exceptional, (1002)
The price is ¥64,011
¥79,483 total
includes taxes & fees
Oct 19 - Oct 20
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Central United States Hotel Reviews

MotorCity Casino Hotel
10/10 Excellent
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Top neighborhoods for Luxury Hotels
More Hotel Options in Central United States
- Adults Only Resorts & Hotels in Central United States
- Adventure Hotels in Central United States
- All-inclusive Hotel in Central United States
- Beach Hotels in Central United States
- Boutique Hotels in Central United States
- Business Hotels in Central United States
- Casinos in Central United States
- Cheap Hotels in Central United States
- Family Hotels in Central United States
- Gay friendly Hotels in Central United States
- Golf Hotels in Central United States
- Green Hotels in Central United States
- Historic Hotels in Central United States
- Hotel Wedding Venues in Central United States
- Hotel with a Concierge in Central United States
- Hotels with Bars in Central United States
- Hotels with Early Check-in in Central United States
- Hotels with Free Parking in Central United States
- Hotels with Hot Tubs in Central United States
- Hotels with Waterslides in Central United States
- Hotels with WiFi in Central United States
- Hotels with a Lazy River in Central United States
- Hotels with a Pool in Central United States
- Hotels with an Indoor Pool in Central United States
- Hotels with smoking rooms in Central United States
- Pet-friendly Hotels in Central United States
- Resorts & Hotels with Spas in Central United States
- Romantic Hotels in Central United States
- Shopping Hotels in Central United States
- Ski Hotels in Central United States
- Waterpark Hotels in Central United States
- Winery Hotels in Central United States
More Accommodation Types in Central United States
- Vacation Homes in United States of America
- Condo Rentals in United States of America
- Apartments in United States of America
- Cabin Rentals in United States of America
- Cottages in United States of America
- Villas in United States of America
- Resorts in United States of America
- Motels in United States of America
- Aparthotels in United States of America
- B&B in United States of America
- Guest Houses in United States of America
- Chalets in United States of America
- Farmstay in United States of America
- Lodges in United States of America
- RV Parks in United States of America
- Houseboats in United States of America
- Town Houses in United States of America
- Inns in United States of America
- Hostels in United States of America
- Condo Resorts in United States of America
- Castles in United States of America
- Residences in United States of America
- Holiday Park Resorts in United States of America
- Ranches in United States of America
- Safari Tentalow in United States of America
- Treehouses in United States of America
- Country Houses in United States of America
- Capsule Hotels in United States of America
- Riads in United States of America
Hotels near popular Central United States Attractions
- Hotels near Wrigley Field
- Hotels near River Walk
- Hotels near Dollywood
- Hotels near Great Smoky Mountains National Park
- Hotels near Mall of America
- Hotels near Port of Galveston Cruise Terminal
- Hotels near Bourbon Street
- Hotels near Cedar Point
- Hotels near Lackland Air Force Base
- Hotels near Naval Base Great Lakes
Central United States Hotels by Star Rating
Explore more hotels
- Comfort Inn Downtown Nashville - Music City Center
- Best Western Downtown Plus Music Row
- Omni Dallas Hotel
- MotorCity Casino Hotel
- Magnolia Hotel Dallas Downtown
- Gaylord Opryland Resort & Convention Center
- The Westin Dallas Fort Worth Airport
- Hollywood Casino at Greektown
- Cambria Hotel Nashville Midtown
- Hollywood Casino & Hotel St. Louis
- Thousand Hills Resort Hotel
- Riverwalk Plaza
- citizenM Austin Downtown
- Hyatt Vacation Club at Wild Oak Ranch, San Antonio
- Moody Gardens Hotel, Spa and Convention Center
- Kozy Houston North
- Sonesta Columbus Downtown
- Beachfront Palms Hotel Galveston
More ways to book
Expedia's Latest Trends
Hotels
Flights
Cars
Packages