Find Resorts & Hotels with Spas in Cairo, IL

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Top Cairo Resorts & Hotels with Spas

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Recommended hotels in Cairo

Quality Inn Cairo I-57

2.5 star property
6.6 out of 10, (269)
"The room smelled like pee and the carpets, hallway and room were filthy. The shower was filthy with paint peeling and mold on the ceiling "
The price is ¥10,158
¥11,273 total
includes taxes & fees
Oct 14 - Oct 15
Quality Inn Cairo I-57

Super 8 by Wyndham Charleston/Sikeston East MO

2.0 star property
6.6 out of 10, (593)
"Thank you!!!"
The price is ¥8,513
¥9,449 total
includes taxes & fees
Sep 29 - Sep 30
Super 8 by Wyndham Charleston/Sikeston East MO

Cozy cabins on beautiful Horseshoe Lake

9.8 out of 10, Exceptional, (34)
"Lovely and homely little get away spot"
The price is ¥15,472
¥19,567 total
includes taxes & fees
Sep 29 - Sep 30
Cozy cabins on beautiful Horseshoe Lake

Quality Inn Charleston - Sikeston

2.5 star property
6.8 out of 10, (403)
"I consistently choose to stay there due to positive past encounters."
The price is ¥9,821
¥10,899 total
includes taxes & fees
Oct 6 - Oct 7
Quality Inn Charleston - Sikeston

Eagle Inn Charleston

2.0 star property
6.8 out of 10, (101)
"Comfortable bed, easy access to room"
The price is ¥9,536
¥10,584 total
includes taxes & fees
Sep 29 - Sep 30
Eagle Inn Charleston

The Rested Duck Mallard Room

9.2 out of 10, Wonderful, (24)
"Great location and we are looking forward to a return trip. "
The price is ¥15,472
¥19,567 total
includes taxes & fees
Sep 29 - Sep 30
The Rested Duck Mallard Room

Charming 3-bedroom house near ball park in quiet neighborhood

10.0 out of 10, Exceptional, (10)
"Quaint stay to see Grand and kids. "
The price is ¥13,454
¥24,006 total
includes taxes & fees
Sep 29 - Sep 30
Charming 3-bedroom house near ball park in quiet neighborhood

Peaceful secluded cabin located near Horseshoe Lake

9.8 out of 10, Exceptional, (18)
"Wasent long enough!"
The price is ¥18,836
¥29,469 total
includes taxes & fees
Sep 29 - Sep 30
Peaceful secluded cabin located near Horseshoe Lake

The Perch - Tiny home perfect for a couples retreat or solo travelers

The price is ¥9,567
¥17,444 total
includes taxes & fees
Sep 30 - Oct 1
The Perch - Tiny home perfect for a couples retreat or solo travelers

Charming Home just minutes from Interstate and Mall

10.0 out of 10, Exceptional, (20)
"We enjoyed staying here very much. Clean and close to where we wanted to be!"
The price is ¥16,444
¥27,976 total
includes taxes & fees
Oct 1 - Oct 2
Charming Home just minutes from Interstate and Mall
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Cairo Hotel Reviews

Frequently asked questions

Looking for a spa hotel in Cairo?
Treat yourself to some time in a luxurious spa hotel and you won't regret it. Check out the historical sites and restaurants in Cairo—your day trip starts here. Enjoy the opera and riverfront during your vacation. Hotels with spas are the perfect way to break out of your routine and add a layer of luxury to your vacation.
What's there to see and do in Cairo?
Enjoy Cairo with a stop at Mississippi River, Fort Defiance State Park, and Columbus-Belmont State Park. If you have a little extra time during your trip, you might want to check out Ullin City Hall and Ballard Wildlife Management Area.
What is a Cairo spa hotel?
Spa hotels in Cairo provide lodging and have an on-site spa offering services including couples massages and beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.