Find 5 Star Hotels in St. Charles, MO from ¥18,381

Start date: Check-in selected.
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on St. Charles 5 Star Hotels

This weekend
Next weekend

Compare St. Charles 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Our top choices for St. Charles 5-star hotels

The Ritz-Carlton, St. Louis

5.0 star property
9.2 out of 10, Wonderful, (546)
"Room was very spacious. The property was immaculate and the service was attentive without be over bearing."
The price is ¥76,319
¥88,904 total
includes taxes & fees
Sep 21 - Sep 22
The Ritz-Carlton, St. Louis

Four Seasons Hotel St Louis

5.0 star property
9.4 out of 10, Exceptional, (1004)
"We’ve stayed at this hotel several times and keep coming back. Great hotel staff and property. "
The price is ¥62,496
¥73,076 total
includes taxes & fees
Sep 2 - Sep 3
Four Seasons Hotel St Louis
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in St. Charles.
Still don't see what you're looking for?
See all properties in St. Charles.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about St. Charles

Stroll down Historic Main Street, where 1812-era charm meets modern boutiques and eateries. Bike the scenic Katy Trail or try your luck at Ameristar Casino before exploring the Lewis & Clark Boathouse.

Top St. Charles Hotel Reviews

Frequently asked questions

How much does it cost to stay in a 5-star hotel in St. Charles?
The amount you pay for a 5-star hotel in St. Charles can vary depending on when you prefer to travel and how long you plan to stay, among a range of factors. Use our price per night filter and other search tools to score the best deal on a high-end stay.

  • Search for the lowest price per night from ¥18,381

What makes a hotel 5 stars in St. Charles?
In St. Charles, a hotel needs to offer a certain number of upscale amenities to earn 5 stars. These can include on-site gyms, saunas and spas, gourmet restaurants, premium bedding, luxury toiletries and more. What also sets 5-star hotels apart is their exceptional service. You'll enjoy things like in-room massages, nightly turn-down services and concierge services. Some may even offer special touches like a welcome gift.
Are there any 5-star all-inclusive resorts in St. Charles?
Find a luxury stay that includes your room, meals, activities and entertainment in St. Charles with our filter tool. Search for resorts with a 5-star rating and select the "All inclusive" filter. Make sure you check what's included in the price. That way, you're ready to take advantage of the premium perks on offer when you arrive.