Find 5 Star Hotels in St. Charles, MO from ¥18,381
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Our top choices for St. Charles 5-star hotels

The Ritz-Carlton, St. Louis
The Ritz-Carlton, St. Louis
9.2 out of 10, Wonderful, (546)
The price is ¥76,319
¥88,904 total
includes taxes & fees
Sep 21 - Sep 22

Four Seasons Hotel St Louis
Four Seasons Hotel St Louis
9.4 out of 10, Exceptional, (1004)
The price is ¥62,496
¥73,076 total
includes taxes & fees
Sep 2 - Sep 3
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Explore similar 4-star hotels
Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in St. Charles.

Renaissance St. Louis Airport Hotel
9801 Natural Bridge Road, St. Louis, MO
The price is ¥18,675 per night from Sep 14 to Sep 15
¥18,675
¥21,847 total
Sep 14 - Sep 15
includes taxes & fees
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Learn more about St. Charles
Stroll down Historic Main Street, where 1812-era charm meets modern boutiques and eateries. Bike the scenic Katy Trail or try your luck at Ameristar Casino before exploring the Lewis & Clark Boathouse.

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