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Find 5 Star Hotels in Santa Cruz from ￥20,354
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Our top choices for Santa Cruz 5-star hotels
9.2 out of 10, Wonderful, (157)
"If I could rate this place 11/10 I would. Despite the fact the hotel and surrounding grounds are incredible, the staff and experiences are what make this place. We have never been somewhere with such exceptional service. Would highly recommend the trip out of Santiago to anyone visiting Chile"
Amy
The price is ￥109,489
￥109,489 total
Jan 7 - Jan 8, 2026
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Explore similar 4-star hotels
Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Santa Cruz.
Santa Cruz Plaza
Plaza De Armas 286 Santa Cruz O'Higgins
The price is ￥20,354 per night from Jan 13 to Jan 14
￥20,354
￥20,354 total
Jan 13 - Jan 14, 2026
8.6/10 Excellent! (335 reviews)
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Learn more about Santa Cruz
Nestled in the heart of wine country, Santa Cruz invites visitors to taste world-class Colchagua Valley wines at family-owned vineyards. Museum of Colchagua showcases impressive pre-Columbian artifacts while the Plaza de Armas offers local crafts and regional foods on weekends.
