A vineyard with rows of grapevines.

Find 5 Star Hotels in Santa Cruz from ￥21,456

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Check availability on Santa Cruz 5 Star Hotels

Tonight
Sep 26 - Sep 27
Tomorrow
Sep 27 - Sep 28
Next weekend
Oct 2 - Oct 4
In two weeks
Oct 9 - Oct 11

Our top choices for Santa Cruz 5-star hotels

A modern bathroom with a large window, a curved bathtub, and a view of a valley.
A wooden deck with a pool, lounge chairs, and umbrellas overlooking a lake with mountains in the background.
A modern building with a unique architectural design, featuring a large, curved roof structure and a well-lit interior.
A modern bedroom with a large bed, a sofa, a small table, and a desk. The room has large windows offering a view of mountains and trees.

1. Vik Chile

Vik Chile
San Vicente
United Kingdom
Andre
￥120,996
￥120,996 total
Oct 18 - Oct 19
Vik Chile
A modern, well-lit building with a glass facade, a wooden deck with lounge chairs, and a hanging light fixture.
A modern bedroom with a bed, bedside table, and a glass table with two wine glasses and a bottle.
A modern bathroom with a wooden vanity, a large mirror, and a hanging light fixture.
A vineyard with rows of grapevines, a swimming pool, and several modern buildings.

2. Vibo Wine Lodge

Vibo Wine Lodge
Santa Cruz
Vibo Wine Lodge
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Santa Cruz.
Santa Cruz Plaza

Santa Cruz Plaza

Plaza De Armas 286 Santa Cruz O'Higgins
￥22,082
￥22,082 total
Sep 28 - Sep 29
8.8/10 Excellent! (373 reviews)
Santa Cruz Plaza
Hotel Cava Colchagua

Hotel Cava Colchagua

Barreales´s Way Santa Cruz O'Higgins
￥21,456
￥21,456 total
Sep 30 - Oct 1
9/10 Wonderful! (177 reviews)
Hotel Cava Colchagua
Barrica Lodge

Barrica Lodge

Ruta I-706 Santa Cruz
Get ratesBarrica Lodge
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Santa Cruz

Nestled in the heart of wine country, Santa Cruz invites visitors to taste world-class Colchagua Valley wines at family-owned vineyards. Museum of Colchagua showcases impressive pre-Columbian artifacts while the Plaza de Armas offers local crafts and regional foods on weekends.

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A vineyard with rows of grapevines, terraced fields, and mountains in the background.

Top Santa Cruz Hotel Reviews